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List of works by Timothy M. Lohman

5'-Single-stranded/duplex DNA junctions are loading sites for E. coli UvrD translocase

scientific article published on 28 September 2010

A Dimer of Escherichia coli UvrD is the active form of the helicase in vitro

scientific article published in January 2003

A nonuniform stepping mechanism for E. coli UvrD monomer translocation along single-stranded DNA

scientific article published on May 2007

A novel chlorophyll protein complex in the repair cycle of photosystem II

scientific article published on 08 October 2019

ATP-dependent translocation of proteins along single-stranded DNA: models and methods of analysis of pre-steady state kinetics

scientific article

Active displacement of RecA filaments by UvrD translocase activity.

scientific article published on 30 March 2015

Are the intrinsically disordered linkers involved in SSB binding to accessory proteins?

scientific article published on 01 September 2019

Asymmetric regulation of bipolar single-stranded DNA translocation by the two motors within Escherichia coli RecBCD helicase

scientific article published on 27 November 2012

Autoinhibition of Escherichia coli Rep monomer helicase activity by its 2B subdomain

scientific article

Bacillus stearothermophilus PcrA monomer is a single-stranded DNA translocase but not a processive helicase in vitro.

scientific article published on 12 July 2007

Binding of the Dimeric Deinococcus radiodurans Single-Stranded DNA Binding Protein to Single-Stranded DNA

scientific article published on September 28, 2010

Binding specificity of Escherichia coli single-stranded DNA binding protein for the chi subunit of DNA pol III holoenzyme and PriA helicase

scientific article published on May 2010

Chemo-mechanical pushing of proteins along single-stranded DNA.

scientific article published on 16 May 2016

DNA unwinding step-size of E. coli RecBCD helicase determined from single turnover chemical quenched-flow kinetic studies

scientific article

DNA-binding orientation and domain conformation of the E. coli rep helicase monomer bound to a partial duplex junction: single-molecule studies of fluorescently labeled enzymes.

scientific article published in February 2004

Defining Single Molecular Forces Required for Notch Activation Using Nano Yoyo.

scientific article published on 11 May 2016

Development of a single-stranded DNA-binding protein fluorescent fusion toolbox

scientific article published on 06 May 2020

Diffusion of human replication protein A along single-stranded DNA.

scientific article

Direct imaging of single UvrD helicase dynamics on long single-stranded DNA

scientific article

Dynamic structural rearrangements between DNA binding modes of E. coli SSB protein.

scientific article published on 5 April 2007

E. coli SSB tetramer binds the first and second molecules of (dT)(35) with heat capacities of opposite sign

scientific article published on 12 May 2011

Effects of monovalent anions on a temperature-dependent heat capacity change for Escherichia coli SSB tetramer binding to single-stranded DNA

scientific article published on April 2006

Effects of temperature and ATP on the kinetic mechanism and kinetic step-size for E.coli RecBCD helicase-catalyzed DNA unwinding

scientific article

Ensemble methods for monitoring enzyme translocation along single stranded nucleic acids

scientific article published on 03 April 2010

Erratum: SSB protein diffusion on single-stranded DNA stimulates RecA filament formation

scientific article published in Nature

Fluorescence Methods to Study DNA Translocation and Unwinding Kinetics by Nucleic Acid Motors

scientific article published on January 1, 2012

General Methods for Analysis of Sequential “n-step” Kinetic Mechanisms: Application to Single Turnover Kinetics of Helicase-Catalyzed DNA Unwinding

scientific article published on October 1, 2003

Glutamate promotes SSB protein-protein Interactions via intrinsically disordered regions

scientific article published on 3 August 2017

Influence of DNA end structure on the mechanism of initiation of DNA unwinding by the Escherichia coli RecBCD and RecBC helicases

scientific article

Initiation and re-initiation of DNA unwinding by the Escherichia coli Rep helicase

scientific article published in October 2002

Intrinsically disordered C-terminal tails of E. coli single-stranded DNA binding protein regulate cooperative binding to single-stranded DNA.

scientific article published on 3 January 2015

Is a fully wrapped SSB-DNA complex essential for Escherichia coli survival?

scientific article published on 15 April 2016

Kinetic mechanism for formation of the active, dimeric UvrD helicase-DNA complex

scientific article

Kinetic mechanism of direct transfer of Escherichia coli SSB tetramers between single-stranded DNA molecules

scientific article published in October 2002

Kinetics of motor protein translocation on single-stranded DNA.

scientific article published on January 2010

Large domain movements upon UvrD dimerization and helicase activation

scientific article published on 30 October 2017

Mechanism of ATP-dependent translocation of E.coli UvrD monomers along single-stranded DNA.

scientific article published in December 2004

Microsecond dynamics of protein-DNA interactions: direct observation of the wrapping/unwrapping kinetics of single-stranded DNA around the E. coli SSB tetramer

scientific article

Modulation of Escherichia coli UvrD Single-Stranded DNA Translocation by DNA Base Composition

scientific article published in October 2017

Multiple C-terminal tails within a single E. coli SSB homotetramer coordinate DNA replication and repair

scientific article published on 07 September 2013

PcrA helicase dismantles RecA filaments by reeling in DNA in uniform steps

scientific article

Plasmodium falciparum SSB Tetramer Binds Single-Stranded DNA Only in a Fully Wrapped Mode

scientific article (publication date: 20 July 2012)

Plasmodium falciparum SSB Tetramer Wraps Single-Stranded DNA with Similar Topology but Opposite Polarity to E. coli SSB

scientific article

Polar destabilization of DNA duplexes with single-stranded overhangs by the Deinococcus radiodurans SSB protein.

scientific article published in December 2006

Probing single-stranded DNA conformational flexibility using fluorescence spectroscopy

scientific article

Processive DNA Unwinding by RecBCD Helicase in the Absence of Canonical Motor Translocation

scientific article published on 12 July 2016

Protein Environment and DNA Orientation Affect Protein-Induced Cy3 Fluorescence Enhancement

scientific article published on 07 June 2019

Protein structure. Direct observation of structure-function relationship in a nucleic acid-processing enzyme

scientific article

Regulation of Nearest-Neighbor Cooperative Binding of E. coli SSB Protein to DNA

scientific article published on 28 October 2019

Regulation of Rep helicase unwinding by an auto-inhibitory subdomain

scientific article published on 01 March 2019

Regulation of UvrD Helicase Activity by MutL

article

Regulation of single-stranded DNA binding by the C termini of Escherichia coli single-stranded DNA-binding (SSB) protein

scientific article

Repetitive shuttling of a motor protein on DNA.

scientific article

Rotations of the 2B Sub-domain of E. coli UvrD Helicase/Translocase Coupled to Nucleotide and DNA Binding

scientific article

SSB as an organizer/mobilizer of genome maintenance complexes

scientific article published on 01 September 2008

SSB binding to ssDNA using isothermal titration calorimetry

scientific article

SSB functions as a sliding platform that migrates on DNA via reptation.

scientific article

SSB protein diffusion on single-stranded DNA stimulates RecA filament formation.

scientific article published on 11 October 2009

SSB-DNA binding monitored by fluorescence intensity and anisotropy

scientific article published on January 2012

Self-assembly of Escherichia coli MutL and its complexes with DNA

scientific article

Self-association equilibria of Escherichia coli UvrD helicase studied by analytical ultracentrifugation

scientific article

Single-Stranded DNA Translocation of E. coli UvrD Monomer Is Tightly Coupled to ATP Hydrolysis

scientific article published on February 14, 2012

Single-molecule nanopositioning: structural transitions of a helicase-DNA complex during ATP hydrolysis

scientific article

Single-molecule views of protein movement on single-stranded DNA.

scientific article published on 23 February 2012

Srs2 prevents Rad51 filament formation by repetitive motion on DNA.

scientific article published on January 2013

Stopped-flow studies of the kinetics of single-stranded DNA binding and wrapping around the Escherichia coli SSB tetramer

scientific article

Structural Mechanisms of Cooperative DNA Binding by Bacterial Single-Stranded DNA-Binding Proteins

scientific article published on 22 November 2018

Structural dynamics of E. coli single-stranded DNA binding protein reveal DNA wrapping and unwrapping pathways.

scientific article

The 2B domain of the Escherichia coli Rep protein is not required for DNA helicase activity

scientific article

The C-terminal domain of full-length E. coli SSB is disordered even when bound to DNA.

scientific article published on 28 May 2004

The Primary and Secondary Translocase Activities within E. coli RecBC Helicase Are Tightly Coupled to ATP Hydrolysis by the RecB Motor

scientific article published on July 20, 2012

Ultrafast redistribution of E. coli SSB along long single-stranded DNA via intersegment transfer

scientific article

UvrD helicase activation by MutL involves rotation of its 2B subdomain

scientific article published on 30 July 2019