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List of works by Tim Mitchison

A High Content Screen in Macrophages Identifies Small Molecule Modulators of STING-IRF3 and NFkB Signaling.

scientific article published on 19 March 2018

A chemical method for fast and sensitive detection of DNA synthesis in vivo

scholarly article

A dynamic view of the proteomic landscape during differentiation of ReNcell VM cells, an immortalized human neural progenitor line

scientific article published on 19 February 2019

A new method reveals microtubule minus ends throughout the meiotic spindle

scientific article

Analysis of mitosis and antimitotic drug responses in tumors by in vivo microscopy and single-cell pharmacodynamics.

scientific article published on 28 June 2011

Caspase-11 regulates cell migration by promoting Aip1-Cofilin-mediated actin depolymerization

scientific article published on 11 February 2007

Chemical genetics to identify NFAT inhibitors: potential of targeting calcium mobilization in immunosuppression

scholarly article

Co-movement of astral microtubules, organelles and F-actin by dynein and actomyosin forces in frog egg cytoplasm

scientific article published on 07 December 2020

Cytoskeleton: what does GTP do for septins?

scientific article

Direct observation of microtubule dynamics at kinetochores in Xenopus extract spindles: implications for spindle mechanics

scientific article

Disassembly of Actin and Keratin Networks by Aurora B Kinase at the Midplane of Cleaving Xenopus laevis Eggs

scientific article published on 06 June 2019

Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils

scientific article published in July 2003

Eg5 causes elongation of meiotic spindles when flux-associated microtubule depolymerization is blocked

scientific article published in November 2004

Exo1: a new chemical inhibitor of the exocytic pathway

scientific article

Fascin-mediated propulsion of Listeria monocytogenes independent of frequent nucleation by the Arp2/3 complex

scientific article

Immunofluorescence of Microtubule Assemblies in Amphibian Oocytes and Early Embryos

scientific article published on 01 January 2019

Is inflammatory micronucleation the key to a successful anti-mitotic cancer drug?

scientific article published in November 2017

Mammalian septins nomenclature

scientific article

Meiotic spindle: sculpted by severing

scientific article published in November 2006

Microtubule Growth Rates Are Sensitive to Global and Local Changes in Microtubule Plus-End Density

scientific article published on 07 June 2020

Microtubule dynamic instability

scientific article published on 01 July 2006

Microtubule plus-end dynamics in Xenopus egg extract spindles

scientific article

Multidimensional drug profiling by automated microscopy

scientific article published in November 2004

Nonredundant functions of Kinesin-13s during meiotic spindle assembly.

scientific article

NuSAP, a mitotic RanGTP target that stabilizes and cross-links microtubules

scientific article

Physical basis of large microtubule aster growth

scientific article

Poleward microtubule flux is a major component of spindle dynamics and anaphase a in mitotic Drosophila embryos

scientific article published in October 2002

Rapid actin monomer-insensitive depolymerization of Listeria actin comet tails by cofilin, coronin, and Aip1.

scientific article

Reassembly of contractile actin cortex in cell blebs

scientific article

Tankyrase-1 polymerization of poly(ADP-ribose) is required for spindle structure and function

scientific article

Targeting cell division: small-molecule inhibitors of FtsZ GTPase perturb cytokinetic ring assembly and induce bacterial lethality

scholarly article

The kinesin Eg5 drives poleward microtubule flux in Xenopus laevis egg extract spindles

scientific article

The majority of the Saccharomyces cerevisiae septin complexes do not exchange guanine nucleotides

scientific article

Toward synthetic cells

scientific article

Tubulin mRNA stability is sensitive to change in microtubule dynamics caused by multiple physiological and toxic cues

article

Vertebrate shugoshin links sister centromere cohesion and kinetochore microtubule stability in mitosis

scientific article

XRHAMM functions in ran-dependent microtubule nucleation and pole formation during anastral spindle assembly

scientific article

shinyDepMap, a tool to identify targetable cancer genes and their functional connections from Cancer Dependency Map data

scientific article published on 08 February 2021

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