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List of works by Reinhold Schäfer

Assay Establishment and Validation of a High-Throughput Screening Platform for Three-Dimensional Patient-Derived Colon Cancer Organoid Cultures

scientific article

Atypical protein kinase C zeta exhibits a proapoptotic function in ovarian cancer.

scientific article

DNA copy number changes define spatial patterns of heterogeneity in colorectal cancer.

scientific article

Discovery and Validation of Novel Biomarkers for Detection of Epithelial Ovarian Cancer

scientific article published on 12 July 2019

Effects of RAL signal transduction in KRAS- and BRAF-mutated cells and prognostic potential of the RAL signature in colorectal cancer

scientific article published on May 2015

Epigenetic regulation of Amphiregulin and Epiregulin in colorectal cancer

scientific article published on 07 November 2018

Heterogeneous pathway activation and drug response modelled in colorectal-tumor-derived 3D cultures

article

Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.

scientific article published on 10 February 2017

Network quantification of EGFR signaling unveils potential for targeted combination therapy.

scientific article published on January 2013

Non-Canonical Hedgehog Signaling Is a Positive Regulator of the WNT Pathway and Is Required for the Survival of Colon Cancer Stem Cells.

scientific article published in December 2017

Ras-mediated deregulation of the circadian clock in cancer

scientific article

Reduced replication origin licensing selectively kills KRAS-mutant colorectal cancer cells via mitotic catastrophe

scientific article published on 01 July 2020

The class II tumour suppressor gene H-REV107-1 is a target of interferon-regulatory factor-1 and is involved in IFNgamma-induced cell death in human ovarian carcinoma cells.

scientific article

The role of the cancer stem cell marker CD271 in DNA damage response and drug resistance of melanoma cells.

scientific article

Transgenic expression of oncogenic BRAF induces loss of stem cells in the mouse intestine, which is antagonized by β-catenin activity

scientific article published on 11 August 2014

Uncoupling of EGFR-RAS signaling and nuclear localization of YBX1 in colorectal cancer

scientific article published on 18 January 2016

Up-regulation of lysyl oxidase in spontaneous revertants of H-ras-transformed rat fibroblasts

scientific article published on October 1, 1993

VIST - a Variant-Information Search Tool for precision oncology

scientific article published on 16 August 2019