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List of works by Kazuhiro Nishimura

Acrolein stimulates the synthesis of IL-6 and C-reactive protein (CRP) in thrombosis model mice and cultured cells.

scientific article published on July 2013

Aggravation of brain infarction through an increase in acrolein production and a decrease in glutathione with aging

scientific article published on 29 March 2016

Brain infarction correlates more closely with acrolein than with reactive oxygen species.

scientific article published on 25 December 2010

Cloning and Expression of Recombinant Chondroitinase ACII and Its Comparison to the Arthrobacter aurescens Enzyme.

scientific article

Defective function of GABA-containing synaptic vesicles in mice lacking the AP-3B clathrin adaptor.

scientific article

Design and synthesis of N1,N8-diacetylspermidine analogues having a linker with desired functional groups

scientific article published on 01 January 2019

Design, synthesis, and biological evaluation of tricyclic heterocycle-tetraamine conjugates as potent NMDA channel blockers

scientific article published on 27 June 2007

Design, synthesis, and evaluation of polyamine-memantine hybrids as NMDA channel blockers

scientific article published on 16 December 2017

Docosahexaenoic acid inhibits cancer cell growth via p27Kip1, CDK2, ERK1/ERK2, and retinoblastoma phosphorylation.

scientific article

Enhancement of the synthesis of RpoN, Cra, and H-NS by polyamines at the level of translation in Escherichia coli cultured with glucose and glutamate.

scientific article published on 12 January 2007

Functional significance of eIF5A and its hypusine modification in eukaryotes

scientific article

Identification and functions of amino acid residues in PotB and PotC involved in spermidine uptake activity.

scientific article published on 11 October 2010

Identification of acrolein-conjugated protein in plasma of patients with brain infarction.

scientific article published on 16 December 2009

Independent roles of eIF5A and polyamines in cell proliferation.

scientific article published on February 2005

Inhibition of cell growth through inactivation of eukaryotic translation initiation factor 5A (eIF5A) by deoxyspergualin.

scientific article published on May 2002

Intense correlation between brain infarction and protein-conjugated acrolein.

scientific article published on 6 August 2009

Inverse correlation between stroke and urinary 3-hydroxypropyl mercapturic acid, an acrolein-glutathione metabolite.

scientific article published on 26 January 2012

KLF4 is required for suppression of histamine synthesis by polyamines during bone marrow-derived mast cell differentiation

scientific article published on 26 February 2020

Methotrexate differentially affects growth of suspension and adherent cells.

scientific article published on May 2004

Polyamine oxidase and acrolein as novel biochemical markers for diagnosis of cerebral stroke.

scientific article

Polyamines release the let-7b-mediated suppression of initiation codon recognition during the protein synthesis of EXT2.

scientific article published on 21 September 2016

Polyphenol extract from Phellinus igniarius protects against acrolein toxicity in vitro and provides protection in a mouse stroke model

scientific article published on 26 March 2015

Role of polyamines at the G1/S boundary and G2/M phase of the cell cycle ⬇️

scientific article published on March 14, 2013

Selective structural change of bulged-out region of double-stranded RNA containing bulged nucleotides by spermidine.

scientific article published on 7 April 2008

Structural Changes of Regulatory Domain Heterodimer of N-Methyl-d-aspartate Receptor Subunits GluN1 and GluN2B through the Binding of Spermine and Ifenprodil ⬇️

scientific article published on June 28, 2012

Structural and functional relationship among diamines in terms of inhibition of cell growth.

scientific article published in October 2004

Structural characterization and immunomodulatory effects of polysaccharides from Phellinus linteus and Phellinus igniarius on the IL-6/IL-10 cytokine balance of the mouse macrophage cell lines (RAW 264.7).

scientific article published on 20 July 2015

Structure and activity of mouse S-adenosylmethionine decarboxylase gene promoters and properties of the encoded proteins ⬇️

scientific article published on June 15, 1998

TATA-binding protein-associated factor 7 regulates polyamine transport activity and polyamine analog-induced apoptosis.

scientific article published on 12 April 2004

Toxic acrolein production due to Ca(2+) influx by the NMDA receptor during stroke.

scientific article published on 14 November 2015

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