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List of works by Simone Engelender

AF-6 Protects Against Dopaminergic Dysfunction and Mitochondrial Abnormalities in Drosophila Models of Parkinson's Disease.

scientific article published on 10 August 2017

AF-6 is a positive modulator of the PINK1/parkin pathway and is deficient in Parkinson's disease.

scientific article published on 07 February 2013

Convergence of Parkin, PINK1, and α-Synuclein on Stress-induced Mitochondrial Morphological Remodeling

scientific article published on 10 April 2015

Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies

scientific article published on 10 April 2017

Glycogen synthase kinase 3beta modulates synphilin-1 ubiquitylation and cellular inclusion formation by SIAH: implications for proteasomal function and Lewy body formation.

scientific article published on 20 September 2005

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Huntingtin-associated protein 1 (HAP1) binds to a Trio-like polypeptide, with a rac1 guanine nucleotide exchange factor domain ⬇️

scientific article published on September 1, 1997

Huntington's Disease and Dentatorubral‐Pallidoluysian Atrophy: Proteins, Pathogenesis and Pathology ⬇️

scientific article published on July 1, 1997

Lipid and immune abnormalities causing age-dependent neurodegeneration and Parkinson's disease

scientific article published on 22 July 2019

Mutation analysis of the seven in absentia homolog 1 (SIAH1) gene in Parkinson's disease

scientific article published on 06 June 2006

Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation

scientific article

Phosphorylation of Parkin by the cyclin-dependent kinase 5 at the linker region modulates its ubiquitin-ligase activity and aggregation.

scientific article published on 27 February 2007

SUMOylation and ubiquitination reciprocally regulate α-synuclein degradation and pathological aggregation

scientific article published on 27 November 2017

Site-specific differences in proteasome-dependent degradation of monoubiquitinated α-synuclein.

scientific article published on October 2013

Synphilin-1 is developmentally localized to synaptic terminals, and its association with synaptic vesicles is modulated by alpha-synuclein

scientific article

Synphilin-1A inhibits seven in absentia homolog (SIAH) and modulates alpha-synuclein monoubiquitylation and inclusion formation.

scientific article published on 17 February 2009

Synphilin-1A: an aggregation-prone isoform of synphilin-1 that causes neuronal death and is present in aggregates from alpha-synucleinopathy patients

scientific article

The Ca2+-ATPase Isoforms of Platelets Are Located in Distinct Functional Ca2+ Pools and Are Uncoupled by a Mechanism Different from That of Skeletal Muscle Ca2+-ATPase ⬇️

scientific article published on 01 September 1995

The NMDA receptor activation by d-serine and glycine is controlled by an astrocytic Phgdh-dependent serine shuttle

scientific article published on 23 September 2019

The PINK1, synphilin-1 and SIAH-1 complex constitutes a novel mitophagy pathway.

scientific article published on 22 June 2016

The Threshold Theory for Parkinson's Disease.

scientific article published on 25 November 2016

Ubiquitination of alpha-synuclein and autophagy in Parkinson's disease.

scientific article

α-Synuclein fate: proteasome or autophagy?

scientific article published on 24 February 2012

α-Synuclein ubiquitination and novel therapeutic targets for Parkinson's disease.

scientific article published on January 2014

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