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List of works by Antje-Christine Walz

Aerobic sn-glycerol-3-phosphate dehydrogenase from Escherichia coli binds to the cytoplasmic membrane through an amphipathic alpha-helix

scientific article

Combining Nonclinical Experiments with Translational PKPD Modeling to Differentiate Erlotinib and Gefitinib.

scientific article published on 16 September 2016

Developing Exposure/Response Models for Anticancer Drug Treatment: Special Considerations

scientific article published on 21 January 2015

First-in-human phase I clinical trial of RG7356, an anti-CD44 humanized antibody, in patients with advanced, CD44-expressing solid tumors.

scientific article published on 5 August 2016

Influence of molecular size on tissue distribution of antibody fragments

scientific article published on 23 October 2015

Model-based assessment of erlotinib effect in vitro measured by real-time cell analysis.

scientific article

No dose adjustment on coadministration of the PDE4 inhibitor roflumilast with a weak CYP3A, CYP1A2, and CYP2C19 inhibitor: an investigation using cimetidine

scientific article published on 19 May 2010

PKPD modeling of acquired resistance to anti-cancer drug treatment.

scientific article published on 31 October 2017

Preclinical optimization of MDM2 antagonist scheduling for cancer treatment by using a model-based approach

scientific article published on 8 May 2014

Predicting In Vivo Efficacy from In Vitro Data: Quantitative Systems Pharmacology Modeling for an Epigenetic Modifier Drug in Cancer

scientific article published on 16 January 2020

Predicting tumor killing and T-cell activation by T-Cell Bispecific antibodies as a function of target expression: combining in vitro experiments with systems modeling

scientific article published on 09 December 2020

Recent developments in using mechanistic cardiac modelling for drug safety evaluation

scientific article

Translational PK/PD modeling to increase probability of success in drug discovery and early development

scientific article published on September 2016

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