List of works by Libor Macůrek

A comprehensive evaluation of pathogenic mutations in primary cutaneous melanomas, including the identification of novel loss-of-function variants

scientific article published on 19 November 2019

ATM/Wip1 activities at chromatin control Plk1 re-activation to determine G2 checkpoint duration.

scientific article published on 12 June 2017

Association of brain gamma-tubulins with alpha beta-tubulin dimers.

scientific article published in August 2002

Aurora-A and hBora join the game of Polo.

scientific article published on June 2009

Bora and Aurora-A continue to activate Plk1 in mitosis

scientific article published on 11 December 2013

CHEK2 Germline Variants in Cancer Predisposition: Stalemate Rather than Checkmate

scientific article published on 12 December 2020

Checkpoint control and cancer.

scientific article published on 03 October 2011

Checkpoint recovery in cells: how a molecular understanding can help in the fight against cancer

scientific article

Cyclin A2 localises in the cytoplasm at the S/G2 transition to activate PLK1

scientific article published on 05 January 2021

Dynein, Lis1 and CLIP-170 counteract Eg5-dependent centrosome separation during bipolar spindle assembly.

scientific article

Expression of human BRCA1Δ17-19 alternative splicing variant with a truncated BRCT domain in MCF-7 cells results in impaired assembly of DNA repair complexes and aberrant DNA damage response.

scientific article

FAM110A promotes mitotic spindle formation by linking microtubules with actin cytoskeleton

scientific article published on 16 July 2024

MRE11 stability is regulated by CK2-dependent interaction with R2TP complex

scientific article published on 24 April 2017

Multigene Panel Germline Testing of 1333 Czech Patients with Ovarian Cancer

scientific article published on 13 April 2020

Nuclear localisation of 53BP1 is regulated by phosphorylation of the nuclear localisation signal.

scientific article published on 30 March 2018

Persistent repair intermediates induce senescence

scientific article published in Nature Communications

Phosphorylation of PLK3 Is Controlled by Protein Phosphatase 6

scientific article published on 20 June 2020

Polo-like kinase 1 inhibits DNA damage response during mitosis

scientific article

Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery

scientific article

Substrate recognition and function of the R2TP complex in response to cellular stress

scientific article

Truncated PPM1D Prevents Apoptosis in the Murine Thymus and Promotes Ionizing Radiation-Induced Lymphoma

scientific article published on 10 September 2020

WIP1 Promotes Homologous Recombination and Modulates Sensitivity to PARP Inhibitors

scientific article published on 15 October 2019

WIP1 phosphatase as pharmacological target in cancer therapy.

scientific article

Wip1 confers G2 checkpoint recovery competence by counteracting p53-dependent transcriptional repression. ⬇️

scientific article

p21 limits S phase DNA damage caused by the Wee1 inhibitor MK1775

scientific article published on 03 April 2019

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