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List of works by A Kuno

(1)H, (13)C, and (15)N chemical shift assignment of the C-terminal 15 kDa domain of a novel galactose-binding protein from the earthworm Lumbricus terrestris.

scientific article

A combined strategy for glycan profiling: a model study with pyridylaminated oligosaccharides

scientific article published on 21 July 2006

A hepatitis C virus (HCV) internal ribosome entry site (IRES) domain III-IV-targeted aptamer inhibits translation by binding to an apical loop of domain IIId

scientific article

A novel glycobiomarker, Wisteria floribunda agglutinin macrophage colony-stimulating factor receptor, for predicting carcinogenesis of liver cirrhosis.

scientific article published on 5 October 2015

A novel serum marker, glycosylated Wisteria floribunda agglutinin-positive Mac-2 binding protein (WFA(+)-M2BP), for assessing liver fibrosis.

scientific article published on 7 March 2014

A novel strategy for mammalian cell surface glycome profiling using lectin microarray.

scientific article published on 10 August 2007

A serum "sweet-doughnut" protein facilitates fibrosis evaluation and therapy assessment in patients with viral hepatitis

scientific article

A standardized method for lectin microarray-based tissue glycome mapping

scientific article

A strategy for discovery of cancer glyco-biomarkers in serum using newly developed technologies for glycoproteomics.

scientific article

A unique N-glycan on human transferrin in CSF: a possible biomarker for iNPH

scientific article published on 03 April 2011

A versatile technology for cellular glycomics using lectin microarray.

scientific article published in January 2010

Alteration of matrix metalloproteinase-3 O-glycan structure as a biomarker for disease activity of rheumatoid arthritis.

scientific article published on 21 May 2016

An Improved Method for Cell Type-Selective Glycomic Analysis of Tissue Sections Assisted by Fluorescence Laser Microdissection ⬇️

scientific article published on 06 February 2019

Application of a glycoproteomics-based biomarker development method: alteration in glycan structure on colony stimulating factor 1 receptor as a possible glycobiomarker candidate for evaluation of liver cirrhosis

scientific article

Application of lectin microarray to crude samples: differential glycan profiling of lec mutants.

scientific article published on March 2006

Assessment of tumor characteristics based on glycoform analysis of membrane-tethered MUC1

scientific article published on 01 October 2017

Assessment of tumor characteristics based on glycoform analysis of membrane-tethered MUC1.

scientific article

Association between Wisteria floribunda agglutinin-positive Mac-2 binding protein and the fibrosis stage of non-alcoholic fatty liver disease

scientific article published on 18 October 2014

Beta3GnT2 (B3GNT2), a major polylactosamine synthase: analysis of B3GNT2-deficient mice

scientific article published on 01 January 2010

Characterization of an exo-beta-1,3-galactanase from Clostridium thermocellum

scientific article

Clinicopathological characteristics and diagnostic performance of Wisteria floribunda agglutinin positive Mac-2-binding protein as a preoperative serum marker of liver fibrosis in hepatocellular carcinoma

scientific article

Comparison of LecT-Hepa and FibroScan for assessment of liver fibrosis in hepatitis B virus infected patients with different ALT levels.

scientific article published on 13 July 2012

Crystal structure of Streptomyces olivaceoviridis E-86 beta-xylanase containing xylan-binding domain

scientific article

Crystal structures of decorated xylooligosaccharides bound to a family 10 xylanase from Streptomyces olivaceoviridis E-86

scientific article

Crystal structures of the sugar complexes of Streptomyces olivaceoviridis E-86 xylanase: sugar binding structure of the family 13 carbohydrate binding module

scientific article

Crystallization and preliminary X-ray crystallographic studies of the C-terminal domain of galactose-binding lectin EW29 from the earthworm Lumbricus terrestris.

scientific article published on 23 September 2004

Crystallographic snapshots of an entire reaction cycle for a retaining xylanase from Streptomyces olivaceoviridis E-86

scientific article

Current Technologies for Complex Glycoproteomics and Their Applications to Biology/Disease-Driven Glycoproteomics

scientific article published on 25 October 2018

Determination of tryptophan tRNA recognition sites for tryptophanyl-tRNA synthetase from hyperthermophilic archaeon, Aeropyrum pernix K1

scientific article published on 01 January 2004

Development and Applications of the Lectin Microarray.

scientific article published on January 2015

Development of a lectin microarray based on an evanescent-field fluorescence principle

scientific article published on 01 January 2006

Differential glycan analysis of an endogenous glycoprotein: toward clinical implementation--from sample pretreatment to data standardization.

scientific article

Differential glycan profiling by lectin microarray targeting tissue specimens

scientific article published on 01 January 2010

Elevated serum levels of Wisteria floribunda agglutinin-positive human Mac-2 binding protein predict the development of hepatocellular carcinoma in hepatitis C patients.

scientific article

Engineering of mucin-type human glycoproteins in yeast cells.

scholarly article

Evidence that Agaricus bisporus agglutinin (ABA) has dual sugar-binding specificity.

scientific article published on 21 June 2006

Functional glycosylation of human podoplanin: glycan structure of platelet aggregation-inducing factor.

scientific article published on 11 January 2007

Glycobiomarker, Fucosylated Short-Form Secretogranin III Levels Are Increased in Serum of Patients with Small Cell Lung Carcinoma.

scientific article

Glycomic Signatures of Plasma IgG Improve Preoperative Prediction of the Invasiveness of Small Lung Nodules

scientific article published on 20 December 2019

Glycoproteomic discovery of serological biomarker candidates for HCV/HBV infection-associated liver fibrosis and hepatocellular carcinoma.

scientific article published on 30 April 2013

Glycoproteomics approach for identifying Glycobiomarker candidate molecules for tissue type classification of non-small cell lung carcinoma.

scientific article published on 22 September 2014

Glycoproteomics-based cancer marker discovery adopting dual enrichment with Wisteria floribunda agglutinin for high specific glyco-diagnosis of cholangiocarcinoma.

scientific article published on 21 April 2013

Hepatic stellate cells secreting WFA+ -M2BP: Its role in biological interactions with Kupffer cells

scientific article published on 22 December 2016

High Throughput ELISAs to Measure a Unique Glycan on Transferrin in Cerebrospinal Fluid: A Possible Extension toward Alzheimer's Disease Biomarker Development

scientific article

Highly Sensitive Glycan Profiling of Hepatitis B Viral Particles and a Simple Method for Dane Particle Enrichment

scientific article published on 20 August 2018

IgA nephropathy caused by unusual polymerization of IgA1 with aberrant N-glycosylation in a patient with monoclonal immunoglobulin deposition disease.

scientific article

Influenza A Virus-Induced Expression of a GalNAc Transferase, GALNT3, via MicroRNAs Is Required for Enhanced Viral Replication

scientific article published on 4 December 2015

Inhibition of tumor cell-induced platelet aggregation using a novel anti-podoplanin antibody reacting with its platelet-aggregation-stimulating domain

scientific journal article

LM-GlycomeAtlas Ver. 1.0: A Novel Visualization Tool for Lectin Microarray-Based Glycomic Profiles of Mouse Tissue Sections

scientific article published on 15 August 2019

LecT-Hepa facilitates estimating treatment outcome during interferon therapy in chronic hepatitis C patients.

scientific article

LecT-Hepa, a glyco-marker derived from multiple lectins, as a predictor of liver fibrosis in chronic hepatitis C patients.

scientific article published on October 2012

LecT-Hepa: A triplex lectin-antibody sandwich immunoassay for estimating the progression dynamics of liver fibrosis assisted by a bedside clinical chemistry analyzer and an automated pretreatment machine.

scientific article published on 30 May 2011

Lectin Bead Array in a Single Tip Facilitates Fully Automatic Glycoprotein Profiling

scientific article published on 22 August 2019

Lectin Microarray-Based Sero-Biomarker Verification Targeting Aberrant O-Linked Glycosylation on Mucin 1.

scientific article published on 7 July 2015

Lectin microarray analyses reveal host cell-specific glycan profiles of the hemagglutinins of influenza A viruses

scientific article published on 29 November 2018

Lectin microarray technology identifies specific lectins related to lymph node metastasis of advanced gastric cancer

scientific article

Lectin-based structural glycomics: a practical approach to complex glycans.

scientific article published on May 2011

Leucyl/Phenylalanyl-tRNA-protein transferase-mediated chemoenzymatic coupling of N-terminal Arg/Lys units in post-translationally processed proteins with non-natural amino acids

scientific article

Leucyl/phenylalanyl (L/F)-tRNA-protein transferase-mediated N-terminal specific labelling of a protein in vitro

scientific article published on 01 January 2003

Mac-2 binding protein glycan isomer (M2BPGi) is a new serum biomarker for assessing liver fibrosis: more than a biomarker of liver fibrosis.

scientific article published on 9 January 2018

Mechanism by which the lectin actinohivin blocks HIV infection of target cells

scientific article

Molecular recognition of proline tRNA by prolyl-tRNA synthetase from hyperthermophilic archaeon, Aeropyrum pernix K1

scientific article published on 01 January 2003

Multilectin-assisted fractionation for improved single-dot tissue glycome profiling in clinical glycoproteomics

scientific article published on 01 February 2014

NMR analysis on the sialic acid-binding mechanism of an R-type lectin mutant by natural evolution-mimicry

scientific article published on 26 May 2016

NMR structure and dynamics of the C-terminal domain of R-type lectin from the earthworm Lumbricus terrestris

scientific article

NMR studies on the interaction of sugars with the C-terminal domain of an R-type lectin from the earthworm Lumbricus terrestris.

scientific article

Novel glycobiomarker for ovarian cancer that detects clear cell carcinoma.

scientific article published on 14 February 2014

O-Glycan-Altered Extracellular Vesicles: A Specific Serum Marker Elevated in Pancreatic Cancer

scientific article published on 31 August 2020

Optimization of evanescent-field fluorescence-assisted lectin microarray for high-sensitivity detection of monovalent oligosaccharides and glycoproteins

scientific article published on 01 August 2008

Polylactosamine on glycoproteins influences basal levels of lymphocyte and macrophage activation.

scholarly article

Purification and characterization of the recombinant Thermus sp. strain T2 alpha-galactosidase expressed in Escherichia coli

scientific article

Rational affinity purification of native Streptomyces family 10 xylanase.

scientific article

Regulation of adult neural progenitor cells by Galectin-1/beta1 Integrin interaction.

scientific article published on 29 March 2010

Response to the letter by Dr. Naoya Yamada, and Dr. Koichi Mizuta regarding our manuscript: "Mac-2 binding protein glycan isomer (M2BPGi) is a new serum biomarker for assessing liver fibrosis: more than a biomarker of liver fibrosis"

scientific article published on 01 February 2019

Serum WFA+ -M2BP levels for evaluation of early stages of liver fibrosis in patients with chronic hepatitis B virus infection.

scientific article published on 14 June 2016

Serum Wisteria Floribunda Agglutinin-Positive Mac-2 Binding Protein Values Predict the Development of Hepatocellular Carcinoma among Patients with Chronic Hepatitis C after Sustained Virological Response.

scientific article published on 12 June 2015

Serum Wisteria Floribunda Agglutinin-Positive Sialylated Mucin 1 as a Marker of Progenitor/Biliary Features in Hepatocellular Carcinoma

scientific article

Significant enhancement in the binding of p-nitrophenyl-beta-D-xylobioside by the E128H mutant F/10 xylanase from Streptomyces olivaceoviridis E-86.

scientific article

Site-directed incorporation of non-natural amino acid into Streptomyces xylanase.

scientific article published on January 2004

Strategy for glycoproteomics: identification of glyco-alteration using multiple glycan profiling tools.

scientific article

Structure and function of a family 10 beta-xylanase chimera of Streptomyces olivaceoviridis E-86 FXYN and Cellulomonas fimi Cex.

scientific article published on 12 April 2004

Structure-inhibition analysis of RNA aptamers that bind to HCV IRES

scientific article published on 01 January 2003

Studies on crenarchaeal tyrosylation accuracy with mutational analyses of tyrosyl-tRNA synthetase and tyrosine tRNA from Aeropyrum pernix

scientific article published on 29 September 2012

Substrate specificity of the alpha-L-arabinofuranosidase from Trichoderma reesei

scientific article published on 01 November 1998

Sugar-complex structures of the C-half domain of the galactose-binding lectin EW29 from the earthworm Lumbricus terrestris

scientific article

Synthesis of a novel histidine analogue and its efficient incorporation into a protein in vivo.

scientific article published in September 2003

Tailoring a novel sialic acid-binding lectin from a ricin-B chain-like galactose-binding protein by natural evolution-mimicry

scientific article

Verification of WFA-Sialylated MUC1 as a Sensitive Biliary Biomarker for Human Biliary Tract Cancer

scientific article

Visualization of galectin-3 oligomerization on the surface of neutrophils and endothelial cells using fluorescence resonance energy transfer

scientific article published on 02 November 2006

Wisteria floribunda agglutinin positive human Mac-2-binding protein as a predictor of hepatocellular carcinoma development in chronic hepatitis C patients

scientific article

Wisteria floribunda agglutinin staining for the quantitative assessment of cardiac fibrogenic activity in a mouse model of dilated cardiomyopathy

scientific article published on 28 June 2019

Wisteria floribunda agglutinin-positive mucin 1 is a sensitive biliary marker for human cholangiocarcinoma.

scientific article published in July 2010

Wisteria floribunda agglutinin-sialylated mucin core polypeptide 1 is a sensitive biomarker for biliary tract carcinoma and intrahepatic cholangiocarcinoma: a multicenter study.

scientific article published on 29 June 2016

[Glycan biomaker in CSF]

scientific article published on 01 November 2010

[Polylactosamine on glycoproteins regulates immune response]

scientific article published on 01 September 2008

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