List of works - Maria T Abreu

6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease.

scientific article published in April 2002

A Noninvasive Method to Assess Mucosal Healing in Patients* With Crohn’s Disease.

scientific article published in May 2018

A Personalized Approach to Managing Inflammatory Bowel Disease

scientific article published on May 2016

A call for investment in education of US minorities in the 21(st) century.

scientific article published on 21 March 2013

A pilot study of adalimumab in infliximab-allergic patients

scientific article published on 01 July 2004

Aberrant expression of the polarity complex atypical PKC and non-muscle myosin IIA in active and inactive inflammatory bowel disease.

scientific article

An evidence-based systematic review on medical therapies for inflammatory bowel disease

scientific article published on April 2011

Anti-TNF failures in Crohn's disease.

scientific article published on January 2011

Antibiotic therapy in inflammatory bowel disease: a systematic review and meta-analysis.

scientific article published on 15 March 2011

Antibodies to I2 predict clinical response to fecal diversion in Crohn's disease

scientific article published on 01 December 2006

Antibodies to tumor necrosis factor-alpha in the treatment of Crohn's disease.

scientific article

Back to the beginning: restarting infliximab in inflammatory bowel disease patients with prior loss of response

scientific article published on 13 April 2014

Biological markers in inflammatory bowel disease: practical consideration for clinicians.

scientific article

Biomarkers in inflammatory bowel disease.

scientific article

Certolizumab pegol in patients with moderate to severe Crohn's disease and secondary failure to infliximab

scientific article published on 6 May 2010

Chromoendoscopy Is More Effective Than Standard Colonoscopy in Detecting Dysplasia During Long-term Surveillance of Patients With Colitis.

scientific article published on December 2015

Chromoendoscopy and Advanced Imaging Technologies for Surveillance of Patients with IBD.

scientific article

Chromoendoscopy-targeted biopsies are superior to standard colonoscopic surveillance for detecting dysplasia in inflammatory bowel disease patients: a prospective endoscopic trial.

scientific article published in September 2008

Clinical outcomes of patients with ulcerative colitis and co-existing Clostridium difficile infection.

scientific article

Colorectal Tumors From Different Racial and Ethnic Minorities Have Similar Rates of Mismatch Repair Deficiency.

scientific article published on April 2016

Combination therapy with infliximab and immunomodulators: is the glass half empty?

scientific article published on 13 May 2008

Commentary: Golimumab in Moderate-to-Severe Ulcerative Colitis

scientific article published on July 2014

Concentrations of 6-thioguanine nucleotide correlate with trough levels of infliximab in patients with inflammatory bowel disease on combination therapy.

scientific article

Cox-2 is regulated by Toll-like receptor-4 (TLR4) signaling: Role in proliferation and apoptosis in the intestine.

scientific article published on September 2006

Crohn's disease in patients who fail infliximab therapy: what does the future hold?

scientific article published on January 2007

DDS Perspective: My Take on Therapeutic Drug Monitoring in IBD

scientific article published on 01 December 2019

DDS Profile: Maria T. Abreu, MD

scientific article published on 01 December 2019

Deciphering the genetic code of gastrointestinal diseases among African Americans

scientific article published on 25 September 2015

Defining subtypes of Crohn's disease patients: the ground work for translational research in inflammatory bowel disease.

scientific article published in January 2003

Design issues and outcomes in IBD clinical trials

scientific article

Developing an instrument to assess the endoscopic severity of ulcerative colitis: the Ulcerative Colitis Endoscopic Index of Severity (UCEIS)

scientific article

Development of Advanced Imaging Criteria for the Endoscopic Identification of Inflammatory Polyps.

scientific article

Diagnosis of colitis: making the initial diagnosis.

scientific article published on March 2007

Diet and Inflammatory Bowel Disease.

scientific article published on August 2015

Diet as Adjunctive Treatment for Inflammatory Bowel Disease: Review and Update of the Latest Literature

scientific article published on 01 June 2019

Diet as a Trigger or Therapy for Inflammatory Bowel Diseases.

scientific article

Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors

scientific article published on 27 June 2017

Early clinical experience with adalimumab in treatment of inflammatory bowel disease with infliximab-treated and naïve patients.

scientific article published on 22 October 2008

Early hepatic nodular hyperplasia and submicroscopic fibrosis associated with 6-thioguanine therapy in inflammatory bowel disease.

scientific article

Editorial: migration studies to determine risk and cause of inflammatory bowel disease-authors' reply.

scientific article published in August 2017

Endoscopy in Inflammatory Bowel Disease

scientific article published on 01 October 2016

Epithelial Toll-like receptors and their role in gut homeostasis and disease

scientific article published on 26 February 2020

Exercise attenuates PCB-induced changes in the mouse gut microbiome.

scientific article

Exposing the Achilles Heel of Antibiotic Therapy for Pouchitis Using Microbial Function and Composition

scientific article published on 19 December 2019

Extracorporeal photopheresis for the treatment of refractory Crohn's disease: results of an open-label pilot study

scientific article published in June 2009

Fluid supplementation accelerates epithelial repair during chemical colitis

scientific article published on 19 April 2019

Gastrointestinal malignancy and the microbiome.

scientific article published on 07 January 2014

Genetic Characterization and Influence on Inflammatory Bowel Disease Expression in a Diverse Hispanic South Florida Cohort

scientific article

Genetics in Diagnosing and Managing Inflammatory Bowel Disease ⬇️

scientific article published on February 24, 2012

Gut microbes in Crohn's disease: getting to know you better?

scientific article published on 01 February 2008

Harnessing the power of bacteria to protect the gut

scientific article published on 01 August 2008

Higher Adalimumab Levels Are Associated with Histologic and Endoscopic Remission in Patients with Crohn's Disease and Ulcerative Colitis

scientific article published on 8 January 2016

Higher infliximab trough levels are associated with perianal fistula healing in patients with Crohn's disease.

scientific article published on 17 February 2017

Hispanics Coming to the US Adopt US Cultural Behaviors and Eat Less Healthy: Implications for Development of Inflammatory Bowel Disease

article

Host-microbe interactions in the small bowel

scientific article

Immunologic regulation of toll-like receptors in gut epithelium.

scientific article

In silico and Ex vivo approaches identify a role for toll-like receptor 4 in colorectal cancer

scientific article

Increased toll-like receptor 4 in cerebral endothelial cells contributes to the astrocyte swelling and brain edema in acute hepatic encephalopathy.

scientific article

Inflammatory Cytokine Profile in Crohn's Disease Nonresponders to Optimal Antitumor Necrosis Factor Therapy

scientific article published on 6 March 2018

Inflammatory bowel disease is associated with an increased incidence of cardiovascular events.

scientific article

Inflammatory bowel disease is presenting sooner after immigration in more recent US immigrants from Cuba.

scientific article published on 19 May 2017

Infliximab in the treatment of medically refractory indeterminate colitis

scientific article published on 01 October 2003

Initiation of inflammatory tumorigenesis by CTLA4 insufficiency due to type 2 cytokines.

scientific article

Innate immunity in the small intestine

scientific article published on 01 March 2012

Intestinal Epithelial Toll-Like Receptor 4 Signaling Affects Epithelial Function and Colonic Microbiota and Promotes a Risk for Transmissible Colitis

scientific article

Intestinal exposure to PCB 153 induces inflammation via the ATM/NEMO pathway

scientific article published on 29 November 2017

Investigation of Microbiota Alterations and Intestinal Inflammation Post-Spinal Cord Injury in Rat Model

scientific article published on 07 June 2018

Is genetic testing in IBD ready for prime time?

scientific article published in February 2004

Letter: Cuban immigrants to the US developing IBD have a progressive shortening of the lag between time of arrival and disease onset. Authors' reply.

scientific article published in October 2017

Lipopolysaccharide potentiates polychlorinated biphenyl-induced disruption of the blood-brain barrier via TLR4/IRF-3 signaling

scientific article

Measurement of vitamin D levels in inflammatory bowel disease patients reveals a subset of Crohn's disease patients with elevated 1,25-dihydroxyvitamin D and low bone mineral density

scientific article published on August 2004

Mesalamine (5-aminosalicylic acid) therapy well tolerated in a patient with aspirin hypersensitivity and ulcerative colitis.

scientific article

Morphine tolerance is attenuated in germfree mice and reversed by probiotics, implicating the role of gut microbiome

scientific article published on 17 June 2019

New insights into the pathogenesis of inflammatory bowel disease.

scientific article

Optimizing therapy with 6-mercaptopurine and azathioprine: to measure or not to measure? ⬇️

scientific article published on September 1, 2010

Pathogen recognition receptors, cancer and inflammation in the gut.

scientific article

Practical techniques for detection of Toll-like receptor-4 in the human intestine.

scientific article published on January 2009

Predictive factors for clinically actionable computed tomography findings in inflammatory bowel disease patients seen in the emergency department with acute gastrointestinal symptoms.

scientific article published on 23 November 2013

Pro-inflammatory human Th17 cells selectively express P-glycoprotein and are refractory to glucocorticoids.

scientific article published on 06 January 2014

Radiation induces proinflammatory dysbiosis: transmission of inflammatory susceptibility by host cytokine induction.

scientific article

Reclassifying Pseudopolyps in Inflammatory Bowel Disease: Histologic and Endoscopic Description in the New Era of Mucosal Healing ⬇️

scientific article published on 15 October 2019

Regulation of Toll-like receptor 4-associated MD-2 in intestinal epithelial cells: a comprehensive analysis.

scientific article

Reliability and initial validation of the ulcerative colitis endoscopic index of severity

scientific article

Rifaximin for the treatment of active pouchitis: a randomized, double-blind, placebo-controlled pilot study

scientific article published on 01 October 2007

Role of vascular endothelial growth factor and angiopoietin systems in serum of Crohnʼs disease patients

scientific article published on 01 January 2008

STRIDE-II: An Update on the Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) Initiative of the International Organization for the Study of IBD (IOIBD): Determining Therapeutic Goals for Treat-to-Target strategies in IBD

scientific article published on 21 December 2020

Safety and efficacy of adalimumab (D2E7) in Crohn's disease patients with an attenuated response to infliximab

scientific article published on 01 January 2005

Selective leukocyte apheresis for the treatment of inflammatory bowel disease.

scientific article

Serologies in Crohn's disease: can we change the gray zone to black and white?

scientific article published on 01 August 2006

Serum Amyloid A as a Surrogate Marker for Mucosal and Histologic Inflammation in Patients with Crohn's Disease.

scientific article published on 7 December 2016

Stool phospholipid signature is altered by diet and tumors

scientific article

TLR4 activates the β-catenin pathway to cause intestinal neoplasia

scientific article

The Impact of Clinical Information on the Assessment of Endoscopic Activity: Characteristics of the Ulcerative Colitis Endoscopic Index Of Severity [UCEIS].

scientific article published on 8 May 2015

The Microbiota and the Immune Response: What Is the Chicken and What Is the Egg?

scientific article published on 05 April 2019

The Viral Mimetic Polyinosinic:Polycytidylic Acid Alters the Growth Characteristics of Small Intestinal and Colonic Crypt Cultures

scientific article

The Xenobiotic Transporter Mdr1 Enforces T Cell Homeostasis in the Presence of Intestinal Bile Acids.

scientific article published in December 2017

The Ying and Yang of bacterial signaling in necrotizing enterocolitis

scientific article published on 21 November 2009

The association of tissue anti-TNF drug levels with serological and endoscopic disease activity in inflammatory bowel disease: the ATLAS study.

scientific article published on 10 February 2015

The genetics and pathogenesis of inflammatory bowel disease

scientific article published on August 2013

The impact of Hispanic ethnicity and race on post-surgical complications in patients with inflammatory bowel disease.

scientific article

The impact of anesthesia providers on major morbidity following screening colonoscopies.

scientific article published on 28 May 2015

The incidence and risk factors for developing depression after being diagnosed with inflammatory bowel disease: a cohort study.

scientific article published on 3 March 2014

The innate immune system and inflammatory bowel disease.

scientific article

The multimatrix mesalamine formulation.

scientific article published on April 2007

The myeloid differentiation factor 88 (MyD88) is required for CD4+ T cell effector function in a murine model of inflammatory bowel disease.

scientific article published on February 2008

The pathogenesis of inflammatory bowel disease: translational implications for clinicians.

scientific article

The role of prostaglandin E2 (PGE 2) in toll-like receptor 4 (TLR4)-mediated colitis-associated neoplasia

scientific article

The spectrum of gastrointestinal toxicity and effect on disease activity of selective cyclooxygenase-2 inhibitors in patients with inflammatory bowel disease.

scientific article published in July 2004

Therapeutic drug monitoring in patients with inflammatory bowel disease

scientific article

Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function.

scientific article

Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis

scientific article published on 01 May 2005

Toll-like receptors (TLRs) and Nod-like receptors (NLRs) in inflammatory disorders.

scientific article published on August 2009

Transcriptional Behavior of Regulatory T Cells Predicts IBD Patient Responses to Vedolizumab Therapy

scientific article published in 2022

Translational research in inflammatory bowel disease.

scientific article published on December 2006

Treating Inflammatory Bowel Disease in Pregnancy: The Issues We Face Today.

scientific article published on 30 June 2015

Treatment With Infliximab Is Associated With Increased Markers of Bone Formation in Patients With Crohn??s Disease

scientific article published on 01 January 2006

United States-Cuba Research Collaborations: Opening Bridges for Gastroenterology

scientific article published on 18 March 2017

Update on idiopathic colitides.

scientific article published on January 2013

Updates in mucosal immunology for inflammatory bowel diseases

scientific article published on 01 November 2018

Use of Cancer Stem Cells to Investigate the Pathogenesis of Colitis-associated Cancer

scientific article

Ustekinumab as Induction and Maintenance Therapy for Ulcerative Colitis

scientific article published on 01 September 2019

What are toll-like receptors and what role may they have in IBD?

scientific article published on 01 October 2008

What is the role and significance of serum and stool biomarkers in the diagnosis of IBD?

scientific article published on 01 October 2008

[The role of translational research in inflammatory bowel disease]

scientific article published on 01 April 2007

List of works by Maria T Abreu

6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease.

A Noninvasive Method to Assess Mucosal Healing in Patients* With Crohn’s Disease.

A Personalized Approach to Managing Inflammatory Bowel Disease

A call for investment in education of US minorities in the 21(st) century.

A pilot study of adalimumab in infliximab-allergic patients

Aberrant expression of the polarity complex atypical PKC and non-muscle myosin IIA in active and inactive inflammatory bowel disease.

An evidence-based systematic review on medical therapies for inflammatory bowel disease

Anti-TNF failures in Crohn's disease.

Antibiotic therapy in inflammatory bowel disease: a systematic review and meta-analysis.

Antibodies to I2 predict clinical response to fecal diversion in Crohn's disease

Antibodies to tumor necrosis factor-alpha in the treatment of Crohn's disease.

Back to the beginning: restarting infliximab in inflammatory bowel disease patients with prior loss of response

Biological markers in inflammatory bowel disease: practical consideration for clinicians.

Biomarkers in inflammatory bowel disease.

Certolizumab pegol in patients with moderate to severe Crohn's disease and secondary failure to infliximab

Chromoendoscopy Is More Effective Than Standard Colonoscopy in Detecting Dysplasia During Long-term Surveillance of Patients With Colitis.

Chromoendoscopy and Advanced Imaging Technologies for Surveillance of Patients with IBD.

Chromoendoscopy-targeted biopsies are superior to standard colonoscopic surveillance for detecting dysplasia in inflammatory bowel disease patients: a prospective endoscopic trial.

Clinical outcomes of patients with ulcerative colitis and co-existing Clostridium difficile infection.

Colorectal Tumors From Different Racial and Ethnic Minorities Have Similar Rates of Mismatch Repair Deficiency.

Combination therapy with infliximab and immunomodulators: is the glass half empty?

Commentary: Golimumab in Moderate-to-Severe Ulcerative Colitis

Concentrations of 6-thioguanine nucleotide correlate with trough levels of infliximab in patients with inflammatory bowel disease on combination therapy.

Cox-2 is regulated by Toll-like receptor-4 (TLR4) signaling: Role in proliferation and apoptosis in the intestine.

Crohn's disease in patients who fail infliximab therapy: what does the future hold?

DDS Perspective: My Take on Therapeutic Drug Monitoring in IBD

DDS Profile: Maria T. Abreu, MD

Deciphering the genetic code of gastrointestinal diseases among African Americans

Defining subtypes of Crohn's disease patients: the ground work for translational research in inflammatory bowel disease.

Design issues and outcomes in IBD clinical trials

Developing an instrument to assess the endoscopic severity of ulcerative colitis: the Ulcerative Colitis Endoscopic Index of Severity (UCEIS)

Development of Advanced Imaging Criteria for the Endoscopic Identification of Inflammatory Polyps.

Diagnosis of colitis: making the initial diagnosis.

Diet and Inflammatory Bowel Disease.

Diet as Adjunctive Treatment for Inflammatory Bowel Disease: Review and Update of the Latest Literature

Diet as a Trigger or Therapy for Inflammatory Bowel Diseases.

Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors

Early clinical experience with adalimumab in treatment of inflammatory bowel disease with infliximab-treated and naïve patients.

Early hepatic nodular hyperplasia and submicroscopic fibrosis associated with 6-thioguanine therapy in inflammatory bowel disease.

Editorial: migration studies to determine risk and cause of inflammatory bowel disease-authors' reply.

Endoscopy in Inflammatory Bowel Disease

Epithelial Toll-like receptors and their role in gut homeostasis and disease

Exercise attenuates PCB-induced changes in the mouse gut microbiome.

Exposing the Achilles Heel of Antibiotic Therapy for Pouchitis Using Microbial Function and Composition

Extracorporeal photopheresis for the treatment of refractory Crohn's disease: results of an open-label pilot study

Fluid supplementation accelerates epithelial repair during chemical colitis

Gastrointestinal malignancy and the microbiome.

Genetic Characterization and Influence on Inflammatory Bowel Disease Expression in a Diverse Hispanic South Florida Cohort

Genetics in Diagnosing and Managing Inflammatory Bowel Disease ⬇️

Gut microbes in Crohn's disease: getting to know you better?

Harnessing the power of bacteria to protect the gut

Higher Adalimumab Levels Are Associated with Histologic and Endoscopic Remission in Patients with Crohn's Disease and Ulcerative Colitis

Higher infliximab trough levels are associated with perianal fistula healing in patients with Crohn's disease.

Hispanics Coming to the US Adopt US Cultural Behaviors and Eat Less Healthy: Implications for Development of Inflammatory Bowel Disease

Host-microbe interactions in the small bowel

Immunologic regulation of toll-like receptors in gut epithelium.

In silico and Ex vivo approaches identify a role for toll-like receptor 4 in colorectal cancer

Increased toll-like receptor 4 in cerebral endothelial cells contributes to the astrocyte swelling and brain edema in acute hepatic encephalopathy.

Inflammatory Cytokine Profile in Crohn's Disease Nonresponders to Optimal Antitumor Necrosis Factor Therapy

Inflammatory bowel disease is associated with an increased incidence of cardiovascular events.

Inflammatory bowel disease is presenting sooner after immigration in more recent US immigrants from Cuba.

Infliximab in the treatment of medically refractory indeterminate colitis

Initiation of inflammatory tumorigenesis by CTLA4 insufficiency due to type 2 cytokines.

Innate immunity in the small intestine

Intestinal Epithelial Toll-Like Receptor 4 Signaling Affects Epithelial Function and Colonic Microbiota and Promotes a Risk for Transmissible Colitis

Intestinal exposure to PCB 153 induces inflammation via the ATM/NEMO pathway

Investigation of Microbiota Alterations and Intestinal Inflammation Post-Spinal Cord Injury in Rat Model

Is genetic testing in IBD ready for prime time?

Letter: Cuban immigrants to the US developing IBD have a progressive shortening of the lag between time of arrival and disease onset. Authors' reply.

Lipopolysaccharide potentiates polychlorinated biphenyl-induced disruption of the blood-brain barrier via TLR4/IRF-3 signaling

Measurement of vitamin D levels in inflammatory bowel disease patients reveals a subset of Crohn's disease patients with elevated 1,25-dihydroxyvitamin D and low bone mineral density

Mesalamine (5-aminosalicylic acid) therapy well tolerated in a patient with aspirin hypersensitivity and ulcerative colitis.

Morphine tolerance is attenuated in germfree mice and reversed by probiotics, implicating the role of gut microbiome

New insights into the pathogenesis of inflammatory bowel disease.

Optimizing therapy with 6-mercaptopurine and azathioprine: to measure or not to measure? ⬇️

Pathogen recognition receptors, cancer and inflammation in the gut.

Practical techniques for detection of Toll-like receptor-4 in the human intestine.

Predictive factors for clinically actionable computed tomography findings in inflammatory bowel disease patients seen in the emergency department with acute gastrointestinal symptoms.

Pro-inflammatory human Th17 cells selectively express P-glycoprotein and are refractory to glucocorticoids.