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List of works by Takuya Fujita

A transcutaneous vaccination system using a hydrogel patch for viral and bacterial infection.

scientific article

Absorption and safety of alendronate, a nitrogen-containing bisphosphonate, after intrapulmonary administration in rats.

scientific article published on 8 September 2010

Amino acids suppress apoptosis induced by sodium laurate, an absorption enhancer.

scientific article published in December 2009

An Openable Artificial Intestinal Tract System Enables the Evaluation of Drug Absorption in Caco-2 Cells through the Reduction in Thickness of the Unstirred Water Layer.

scientific article published in January 2019

Assessment of contribution of BCRP to intestinal absorption of various drugs using portal-systemic blood concentration difference model in mice

scientific article published on 17 January 2020

Bottom-Up Physiologically Based Oral Absorption Modeling of Free Weak Base Drugs

scientific article published on 03 September 2020

CC-chemokine ligand 17 gene therapy induces tumor regression through augmentation of tumor-infiltrating immune cells in a murine model of preexisting CT26 colon carcinoma.

scientific article

Carrageenans can regulate the pulmonary absorption of antiasthmatic drugs and their retention in the rat lung tissues without any membrane damage.

scientific article published in April 2005

Cloning and Functional Expression of a cDNA Encoding a Mammalian Sodium-dependent Vitamin Transporter Mediating the Uptake of Pantothenate, Biotin, and Lipoate ⬇️

scientific article published on March 27, 1998

Colon-specific delivery and enhanced colonic absorption of [Asu(1,7)]-eel calcitonin using chitosan capsules containing various additives in rats

scientific article published on 01 April 2006

Colon-specific delivery of budesonide with azopolymer-coated pellets: therapeutic effects of budesonide with a novel dosage form against 2,4,6-trinitrobenzenesulphonic acid-induced colitis in rats

scientific article published on 01 March 1999

Control of pulmonary absorption of water-soluble compounds by various viscous vehicles.

scientific article published in September 2004

Creation and X-ray structure analysis of the tumor necrosis factor receptor-1-selective mutant of a tumor necrosis factor-alpha antagonist

scientific article

Dendritic cells transduced with gp100 gene by RGD fiber-mutant adenovirus vectors are highly efficacious in generating anti-B16BL6 melanoma immunity in mice.

scientific article published in October 2003

Development of magnetic anionic liposome/atelocollagen complexes for efficient magnetic drug targeting

scientific article published in November 2017

Development of oligoarginine–drug conjugates linked to new peptidic self-cleavable spacers toward effective intestinal absorption

article

Dextran sodium sulfate alters cytokine production in macrophages in vitro

scientific article published in November 2016

Effect of Mechanical Agitation on Cationic Liposome Transport across an Unstirred Water Layer in Caco-2 Cells.

scientific article published in January 2016

Effect of surface charge, particle size, and modification by polyethylene glycol of liposomes on their association with Caco-2 cells across an unstirred water layer.

scientific article published in January 2018

Efficient antigen gene transduction using Arg-Gly-Asp fiber-mutant adenovirus vectors can potentiate antitumor vaccine efficacy and maturation of murine dendritic cells ⬇️

scientific article published on November 1, 2001

Enhanced macrophage delivery to the colon using magnetic lipoplexes with a magnetic field

scientific article published on 01 December 2019

Enhanced transdermal delivery of phenylalanyl-glycine by chemical modification with various fatty acids.

scientific article published in January 2003

Enhancement of intestinal transport of thyrotropin-releasing hormone via a carrier-mediated transport system by chemical modification with lauric acid

scientific article published on 01 August 1996

Enhancement of the small intestinal uptake of phenylalanyl-glycine via a H+/oligopeptide transport system by chemical modification with fatty acids ⬇️

scientific article published on 01 January 1997

Excellent absorption enhancing characteristics of NO donors for improving the intestinal absorption of poorly absorbable compound compared with conventional absorption enhancers

scientific article published on 01 June 2006

Exon‐Intron Structure, Analysis of Promoter Region, and Chromosomal Localization of the Human Type 1 σ Receptor Gene ⬇️

scientific article published on February 1, 1998

Extra-Renal Elimination of Uric Acid via Intestinal Efflux Transporter BCRP/ABCG2 ⬇️

scientific article published on February 10, 2012

Factors involved in the maturation of murine dendritic cells transduced with adenoviral vector variants

scientific article published on 12 February 2008

Functional characterization and cloning of amino acid transporter B(0,+) (ATB(0,+)) in primary cultured rat pneumocytes.

scientific article published in March 2008

Functional characterization of Na+ -coupled citrate transporter NaC2/NaCT expressed in primary cultures of neurons from mouse cerebral cortex.

scientific article published on 6 March 2006

Functional characterization of Na+-independent choline transport in primary cultures of neurons from mouse cerebral cortex.

scientific article published on 18 October 2005

Functional characterization of Zn2(+)-sensitive GABA transporter expressed in primary cultures of astrocytes from rat cerebral cortex

scientific journal article

Functional expression and adaptive regulation of Na+ -dependent neutral amino acid transporter SNAT2/ATA2 in normal human astrocytes under amino acid starved condition.

scientific article

Functional expression of taurine transporter and its up-regulation in developing neurons from mouse cerebral cortex.

scientific article published on 28 March 2006

Generation of HepG2 Cells with High Expression of Multiple Drug-Metabolizing Enzymes for Drug Discovery Research Using a PITCh System

Halothane attenuates the cerebroprotective action of several Na+ and Ca2+ channel blockers via reversal of their ion channel blockade.

scientific article published in October 2002

Identification of a Potential Substrate Binding Domain in the Mammalian Peptide Transporters PEPT1 and PEPT2 Using PEPT1-PEPT2 and PEPT2-PEPT1 Chimeras ⬇️

scientific article published on May 8, 1998

Identity of the high-affinity sodium/carboxylate cotransporter NaC3 as the N-acetyl-L-aspartate transporter

scientific article published on January 2006

Improvement of absorption enhancing effects of n-dodecyl-beta-D-maltopyranoside by its colon-specific delivery using chitosan capsules.

scientific article

Improvement of intestinal absorption of water-soluble macromolecules by various polyamines: intestinal mucosal toxicity and absorption-enhancing mechanism of spermine.

scientific article

Improvement of pulmonary absorption of insulin and other water-soluble compounds by polyamines in rats

scientific article published on 27 June 2007

Influence of Physicochemical Properties and PEG Modification of Magnetic Liposomes on Their Interaction with Intestinal Epithelial Caco-2 Cells.

scientific article

Interaction of kyotorphin and brain peptide transporter in synaptosomes prepared from rat cerebellum: implication of high affinity type H+/peptide transporter PEPT2 mediated transport system.

scientific article published in August 1999

Intranasal immunization with poly(γ-glutamic acid) nanoparticles entrapping antigenic proteins can induce potent tumor immunity.

scientific article published on 22 March 2011

Modulation of intestinal P-glycoprotein function by polyethylene glycols and their derivatives by in vitro transport and in situ absorption studies.

scientific article published on 24 February 2006

Nitric oxide donors can enhance the intestinal transport and absorption of insulin and [Asu(1,7)]-eel calcitonin in rats.

scientific article published in September 2005

Oligoarginine-based prodrugs with self-cleavable spacers for caco-2 cell permeation.

scientific article published on November 2008

Oseltamivir (Tamiflu) efflux transport at the blood-brain barrier via P-glycoprotein.

scientific article

P-glycoprotein restricts the penetration of oseltamivir across the blood-brain barrier.

scientific article published on 26 November 2007

Permeability characteristics of tetragastrins across intestinal membranes using the Caco-2 monolayer system: comparison between acylation and application of protease inhibitors

scientific article published on September 1, 1998

Pharmaceutical stability of colloidal saccharated iron oxide injection in normal saline.

scientific article

Pharmacokinetic Modeling and Monte Carlo Simulation to Predict Interindividual Variability in Human Exposure to Oseltamivir and Its Active Metabolite, Ro 64-0802.

scientific article

Pharmacokinetic interaction study of sulphasalazine in healthy subjects and the impact of curcumin as an in vivo inhibitor of BCRP ⬇️

scientific article published on July 1, 2012

Prediction Accuracy of Mechanism-Based Oral Absorption Model for Dogs

scientific article published on 21 March 2019

Quantitative evaluation of the impact of active efflux by p-glycoprotein and breast cancer resistance protein at the blood-brain barrier on the predictability of the unbound concentrations of drugs in the brain using cerebrospinal fluid concentratio

scientific article published on 20 September 2011

Studies on the intestinal absorption characteristics of sulfasalazine, a breast cancer resistance protein (BCRP) substrate.

scientific article published on 3 July 2012

Susceptibility of ebiratide to proteolysis in rat intestinal fluid and homogenates and its protection by various protease inhibitors

scientific article published on 01 January 1994

Transport characteristics of 5-aminosalicylic acid into colonic epithelium: Involvement of sodium-coupled monocarboxylate transporter SMCT1-mediated transport system

scientific article published on 31 January 2020

Tumor suppressive efficacy through augmentation of tumor-infiltrating immune cells by intratumoral injection of chemokine-expressing adenoviral vector.

scientific article published on April 2006

Two oligopeptide transporters from Caenorhabditis elegans:molecular cloning and functional expression ⬇️

scientific article published on June 1, 1998

What kinds of substrates show P-glycoprotein-dependent intestinal absorption? Comparison of verapamil with vinblastine

scientific article published on 01 June 2006

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