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List of works by Sidney Strickland

A critical role for plasminogen in inflammation

scientific article published on 01 April 2020

A novel Aβ-fibrinogen interaction inhibitor rescues altered thrombosis and cognitive decline in Alzheimer's disease mice

scientific article

A novel detection method of cleaved plasma high-molecular-weight kininogen reveals its correlation with Alzheimer's pathology and cognitive impairment

scientific article published on 04 August 2018

A possible new role for Aβ in vascular and inflammatory dysfunction in Alzheimer's disease.

scientific article published on May 2016

Ablation of astrocytic laminin impairs vascular smooth muscle cell function and leads to hemorrhagic stroke.

scientific article published on 15 July 2013

Abnormal clotting of the intrinsic/contact pathway in Alzheimer disease patients is related to cognitive ability

scientific article published on 01 May 2018

Activation of the factor XII-driven contact system in Alzheimer's disease patient and mouse model plasma

scientific article

Advantage of knowing nature's secrets

Alzheimer's disease peptide beta-amyloid interacts with fibrinogen and induces its oligomerization.

scientific article

Aminopyrimidine Class Aggregation Inhibitor Effectively Blocks Aβ-Fibrinogen Interaction and Aβ-Induced Contact System Activation.

scientific article published on 2 February 2018

An antibody against HK blocks Alzheimer's disease peptide β-amyloid-induced bradykinin release in human plasma

scientific article published on 28 October 2019

An extracellular proteolytic cascade promotes neuronal degeneration in the mouse hippocampus

scientific article published on 01 January 1997

Analysis of β-Amyloid-induced Abnormalities on Fibrin Clot Structure by Spectroscopy and Scanning Electron Microscopy

scientific article published on 30 November 2018

Astrocytic laminin regulates pericyte differentiation and maintains blood brain barrier integrity.

scientific article published on 3 March 2014

Aβ delays fibrin clot lysis by altering fibrin structure and attenuating plasminogen binding to fibrin.

scientific article published on 11 January 2012

Biochemical and structural analysis of the interaction between β-amyloid and fibrinogen.

scientific article published on 7 July 2016

Blood will out: vascular contributions to Alzheimer's disease.

scientific article published in February 2018

Blood-derived plasminogen drives brain inflammation and plaque deposition in a mouse model of Alzheimer's disease

article published in the Proceedings of the National Academy of Sciences of the United States of America

Both laminin and Schwann cell dystroglycan are necessary for proper clustering of sodium channels at nodes of Ranvier.

scientific article published on October 2005

Cerebral amyloid angiopathy-linked β-amyloid mutations promote cerebral fibrin deposits via increased binding affinity for fibrinogen

scientific article published on 09 June 2020

Chronic Hypertension Leads to Neurodegeneration in the TgSwDI Mouse Model of Alzheimer's Disease

scientific article published on 4 May 2015

Cortical deficiency of laminin gamma1 impairs the AKT/GSK-3beta signaling pathway and leads to defects in neurite outgrowth and neuronal migration.

scientific article

Cytoplasmic polyadenylation of Toll mRNA is required for dorsal-ventral patterning in Drosophila embryogenesis ⬇️

scientific article published on August 1, 1998

Disruption of laminin in the peripheral nervous system impedes nonmyelinating Schwann cell development and impairs nociceptive sensory function.

scientific article published on June 2009

Dissociation of mRNA cytoplasmic polyadenylation from translational activation by structural modification of the 5'-UTR

scientific article

Exogenous tissue plasminogen activator enhances peripheral nerve regeneration and functional recovery after injury in mice.

scientific article published in January 2006

Extracellular proteases in neuronal function and degeneration

scientific article published on January 1, 1996

Fibrin depletion decreases inflammation and delays the onset of demyelination in a tumor necrosis factor transgenic mouse model for multiple sclerosis.

scientific article

Fibrin deposited in the Alzheimer's disease brain promotes neuronal degeneration

scientific article published on 31 October 2014

Fibrin inhibits peripheral nerve remyelination by regulating Schwann cell differentiation

scientific article published on 01 March 2002

Fibrin is a regulator of Schwann cell migration after sciatic nerve injury in mice

scientific article published on 01 March 2003

Fibrinogen and beta-amyloid association alters thrombosis and fibrinolysis: a possible contributing factor to Alzheimer's disease

scientific article

Fibrinogen in the Nervous System: Glia Beware.

scientific article published in December 2017

Hyperhomocysteinemia exacerbates Alzheimer's disease pathology by way of the β-amyloid fibrinogen interaction

scientific article published on 19 April 2016

Inflaming the Brain

scientific article published on 01 March 2019

Interactions of β-amyloid peptide with fibrinogen and coagulation factor XII may contribute to Alzheimer's disease

scientific article published on 28 June 2017

Involvement of tissue plasminogen activator in stress responsivity during acute cocaine withdrawal in mice.

scientific article published on 28 July 2010

Knockdown of circulating C1 inhibitor induces neurovascular impairment, glial cell activation, neuroinflammation, and behavioral deficits

scientific article published on 18 March 2019

Laminin gamma1 is critical for Schwann cell differentiation, axon myelination, and regeneration in the peripheral nerve

scientific article

Laminin is required for Schwann cell morphogenesis

scientific article

Laminin regulates PDGFRβ(+) cell stemness and muscle development.

scientific article

Localization and regulation of the tissue plasminogen activator-plasmin system in the hippocampus.

scientific article published in March 2002

Long-Term Dabigatran Treatment Delays Alzheimer's Disease Pathogenesis in the TgCRND8 Mouse Model

scientific article published on 01 October 2019

Mapping of Drosophila Mutations Using Site-Specific Male Recombination ⬇️

scientific article published on May 1, 1998

Membrane depolarization induces calcium-dependent secretion of tissue plasminogen activator.

scientific article

Mesenchymal stem cells facilitate axon sorting, myelination, and functional recovery in paralyzed mice deficient in Schwann cell-derived laminin.

scientific article

Modulation of sympathetic activity by tissue plasminogen activator is independent of plasminogen and urokinase

scientific article published on 11 April 2007

Nanos and pumilio establish embryonic polarity in Drosophila by promoting posterior deadenylation of hunchback mRNA ⬇️

scientific article published on August 1, 1997

Neuronal Death in the Hippocampus Is Promoted by Plasmin-Catalyzed Degradation of Laminin ⬇️

scientific article published on December 26, 1997

Neuronal death in the central nervous system demonstrates a non-fibrin substrate for plasmin ⬇️

scientific article published on September 2, 1997

Neutrophil adhesion in brain capillaries reduces cortical blood flow and impairs memory function in Alzheimer's disease mouse models

scientific article published on 11 February 2019

Plasmin deficiency leads to fibrin accumulation and a compromised inflammatory response in the mouse brain

scientific article

Plasminogen mediates communication between the peripheral and central immune systems during systemic immune challenge with lipopolysaccharide

scientific article published on 28 August 2019

Proteolytic fragments of laminin promote excitotoxic neurodegeneration by up-regulation of the KA1 subunit of the kainate receptor

scientific article

Regulation of Schwann cell function by the extracellular matrix.

scientific article

Removal of tissue plasminogen activator does not protect against neuronal degeneration in the cerebellum of the weaver mouse ⬇️

scientific article published on October 24, 1997

Stress-induced spine loss in the medial amygdala is mediated by tissue-plasminogen activator.

scientific article published on 16 October 2006

The APOE ε4/ε4 Genotype Potentiates Vascular Fibrin(Ogen) Deposition in Amyloid-Laden Vessels in the Brains of Alzheimer's Disease Patients ⬇️

scientific article published on 08 May 2013

The Alzheimer's disease peptide β-amyloid promotes thrombin generation through activation of coagulation factor XII.

scientific article published on 28 November 2015

The Alzheimer's disease peptide β-amyloid promotes thrombin generation through activation of coagulation factor XII: reply.

scientific article

The GluK4 kainate receptor subunit regulates memory, mood, and excitotoxic neurodegeneration.

scientific article

The Possible Role of Tissue-Type Plasminogen Activator (tPA) and tPA Blockers in the Pathogenesis and Treatment of Alzheimer's Disease ⬇️

scientific article published on January 1, 2003

The cellular origin of laminin determines its role in blood pressure regulation

scientific article

The plasminogen activator system modulates sympathetic nerve function.

scientific article

The tissue plasminogen activator-plasminogen proteolytic cascade accelerates amyloid-beta (Abeta) degradation and inhibits Abeta-induced neurodegeneration.

scientific article

Tissue plasminogen activator (tPA) increase neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice ⬇️

scientific article published on February 1, 1998

Tissue plasminogen activator in the bed nucleus of stria terminalis regulates acoustic startle.

scientific article published on 26 August 2005

Tissue plasminogen activator is required for the development of fetal alcohol syndrome in mice.

scientific article

Tissue plasminogen activator modulates the cellular and behavioral response to cocaine.

scholarly article

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