List of works - Stephen Cannon

A calcium channel mutant mouse model of hypokalemic periodic paralysis ⬇️

scientific article published on November 26, 2012

A four-electrode method to study dynamics of ion activity and transport in skeletal muscle fibers

scientific article published on 18 July 2019

A proposed mutation, Val781Ile, associated with hyperkalemic periodic paralysis and cardiac dysrhythmia is a benign polymorphism ⬇️

scientific article published on August 1, 1997

A sodium channel knockin mutant (NaV1.4-R669H) mouse model of hypokalemic periodic paralysis ⬇️

scientific article published on September 1, 2011

An atypical CaV1.1 mutation reveals a common mechanism for hypokalemic periodic paralysis.

scientific article published on 14 November 2017

Beneficial effects of bumetanide in a CaV1.1-R528H mouse model of hypokalaemic periodic paralysis

scientific article published on 18 October 2013

Bilateral third nerve palsy and temporal arteritis.

scientific article

Bumetanide prevents transient decreases in muscle force in murine hypokalemic periodic paralysis.

scientific article published on 20 February 2013

Disrupted coupling of gating charge displacement to Na+ current activation for DIIS4 mutations in hypokalemic periodic paralysis

scientific article

Enhanced slow inactivation by V445M: a sodium channel mutation associated with myotonia

scientific article

Gating behaviour of sodium currents in adult mouse muscle recorded with an improved two-electrode voltage clamp.

scientific article published on 6 December 2010

Human sodium channel gating defects caused by missense mutations in S6 segments associated with myotonia: S804F and V1293I ⬇️

scientific article published on August 1, 1998

Identification and functional characterization of Kir2.6 mutations associated with non-familial hypokalemic periodic paralysis.

scientific article

Kv4.2 autism and epilepsy mutation enhances inactivation of closed channels but impairs access to inactivated state after opening.

scientific article

Leaky sodium channels from voltage sensor mutations in periodic paralysis, but not paramyotonia

scientific article

Mice with an NaV1.4 sodium channel null allele have latent myasthenia, without susceptibility to periodic paralysis

scientific article published on 05 April 2016

Mind the magnesium, in dantrolene suppression of malignant hyperthermia.

scientific article published on 25 April 2017

Modification of the Na+ current conducted by the rat skeletal muscle ? subunit by coexpression with a human brain ? subunit ⬇️

scientific article published on April 1, 1993

Myasthenic congenital myopathy from recessive mutations at a single residue in Na1.4

scientific article published on 01 March 2019

New territory opened by periodic paralysis associated with mitochondrial DNA mutation.

scientific article published on 23 October 2013

Nondystrophic myotonia: challenges and future directions.

scientific article published on 18 December 2013

Paradoxical depolarization of BA2+- treated muscle exposed to low extracellular K+: insights into resting potential abnormalities in hypokalemic paralysis.

scientific article

Pathomechanisms in channelopathies of skeletal muscle and brain

scientific article (publication date: 21 July 2006)

Randomized, placebo-controlled trials of dichlorphenamide in periodic paralysis.

scientific article published on 10 February 2016

Recovery from acidosis is a robust trigger for loss of force in murine hypokalemic periodic paralysis

scientific article published on 07 February 2019

Resurgent and Gating Pore Currents Induced by De Novo SCN2A Epilepsy Mutations

scientific article published on 01 September 2019

Review of the Diagnosis and Treatment of Periodic Paralysis.

scientific article published on 10 November 2017

Skeletal muscle channelopathy: a new risk for sudden infant death syndrome.

scientific article published on 28 March 2018

Skeletal muscle-specific T-tubule protein STAC3 mediates voltage-induced Ca2+ release and contractility

scientific journal article

Slow inactivation of the NaV1.4 sodium channel in mammalian cells is impeded by co-expression of the beta1 subunit

scientific article

Small fiber neuropathy: a bit less idiopathic?

scientific article published on 25 April 2012

Sodium Channelopathies of Skeletal Muscle.

scientific article published on 23 September 2017

Sodium channels gone wild: resurgent current from neuronal and muscle channelopathies.

scientific article

Stac3 enhances expression of human CaV1.1 in Xenopus oocytes and reveals gating pore currents in HypoPP mutant channels.

scientific article published on 31 January 2018

Targeted mutation of mouse skeletal muscle sodium channel produces myotonia and potassium-sensitive weakness.

scientific article

The common missense mutation D489N in TRIM32 causing limb girdle muscular dystrophy 2H leads to loss of the mutated protein in knock-in mice resulting in a Trim32-null phenotype

scientific journal article

The non-dystrophic myotonias: molecular pathogenesis, diagnosis and treatment.

scientific article

The position of the fast-inactivation gate during lidocaine block of voltage-gated Na+ channels

scientific article

β-Catenin stabilization in skeletal muscles, but not in motor neurons, leads to aberrant motor innervation of the muscle during neuromuscular development in mice

scientific article

List of works by Stephen Cannon

A calcium channel mutant mouse model of hypokalemic periodic paralysis ⬇️

A four-electrode method to study dynamics of ion activity and transport in skeletal muscle fibers

A proposed mutation, Val781Ile, associated with hyperkalemic periodic paralysis and cardiac dysrhythmia is a benign polymorphism ⬇️

A sodium channel knockin mutant (NaV1.4-R669H) mouse model of hypokalemic periodic paralysis ⬇️

An atypical CaV1.1 mutation reveals a common mechanism for hypokalemic periodic paralysis.

Beneficial effects of bumetanide in a CaV1.1-R528H mouse model of hypokalaemic periodic paralysis

Bilateral third nerve palsy and temporal arteritis.

Bumetanide prevents transient decreases in muscle force in murine hypokalemic periodic paralysis.

Disrupted coupling of gating charge displacement to Na+ current activation for DIIS4 mutations in hypokalemic periodic paralysis

Enhanced slow inactivation by V445M: a sodium channel mutation associated with myotonia

Gating behaviour of sodium currents in adult mouse muscle recorded with an improved two-electrode voltage clamp.

Human sodium channel gating defects caused by missense mutations in S6 segments associated with myotonia: S804F and V1293I ⬇️

Identification and functional characterization of Kir2.6 mutations associated with non-familial hypokalemic periodic paralysis.

Kv4.2 autism and epilepsy mutation enhances inactivation of closed channels but impairs access to inactivated state after opening.

Leaky sodium channels from voltage sensor mutations in periodic paralysis, but not paramyotonia

Mice with an NaV1.4 sodium channel null allele have latent myasthenia, without susceptibility to periodic paralysis

Mind the magnesium, in dantrolene suppression of malignant hyperthermia.

Modification of the Na+ current conducted by the rat skeletal muscle ? subunit by coexpression with a human brain ? subunit ⬇️

Myasthenic congenital myopathy from recessive mutations at a single residue in Na1.4

New territory opened by periodic paralysis associated with mitochondrial DNA mutation.

Nondystrophic myotonia: challenges and future directions.

Paradoxical depolarization of BA2+- treated muscle exposed to low extracellular K+: insights into resting potential abnormalities in hypokalemic paralysis.

Pathomechanisms in channelopathies of skeletal muscle and brain

Randomized, placebo-controlled trials of dichlorphenamide in periodic paralysis.

Recovery from acidosis is a robust trigger for loss of force in murine hypokalemic periodic paralysis

Resurgent and Gating Pore Currents Induced by De Novo SCN2A Epilepsy Mutations

Review of the Diagnosis and Treatment of Periodic Paralysis.

Skeletal muscle channelopathy: a new risk for sudden infant death syndrome.

Skeletal muscle-specific T-tubule protein STAC3 mediates voltage-induced Ca2+ release and contractility

Slow inactivation of the NaV1.4 sodium channel in mammalian cells is impeded by co-expression of the beta1 subunit

Small fiber neuropathy: a bit less idiopathic?

Sodium Channelopathies of Skeletal Muscle.

Sodium channels gone wild: resurgent current from neuronal and muscle channelopathies.

Stac3 enhances expression of human CaV1.1 in Xenopus oocytes and reveals gating pore currents in HypoPP mutant channels.

Targeted mutation of mouse skeletal muscle sodium channel produces myotonia and potassium-sensitive weakness.

The common missense mutation D489N in TRIM32 causing limb girdle muscular dystrophy 2H leads to loss of the mutated protein in knock-in mice resulting in a Trim32-null phenotype

The non-dystrophic myotonias: molecular pathogenesis, diagnosis and treatment.

The position of the fast-inactivation gate during lidocaine block of voltage-gated Na+ channels

β-Catenin stabilization in skeletal muscles, but not in motor neurons, leads to aberrant motor innervation of the muscle during neuromuscular development in mice