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List of works by Johnathan D Tune

ATP-dependent K(+) channels contribute to local metabolic coronary vasodilation in experimental diabetes.

scientific article published in April 2002

Adaptations in the balance between coronary blood flow and myocardial metabolism in endurance athletes

scientific article published on 01 November 2008

Alpha-adrenergic vasoconstrictor tone limits right coronary blood flow in exercising dogs.

scientific article published in April 2004

Benefits of Empagliflozin Beyond Enhancing Myocardial Energetics?

scientific article published on 01 August 2019

Bi-ventricular pacing improves pump function only with adequate myocardial perfusion in canine hearts with pseudo-left bundle branch block

scientific article published on 19 June 2012

Biphasic alterations in coronary smooth muscle Ca(2+) regulation in a repeat cross-sectional study of coronary artery disease severity in metabolic syndrome

scientific article published on 26 March 2016

Bromoenol Lactone Inhibits Voltage-Gated Ca2+and Transient Receptor Potential Canonical Channels ⬇️

scientific article published on July 27, 2011

C-reactive protein does not relax vascular smooth muscle: effects mediated by sodium azide in commercially available preparations.

scientific article published on 24 November 2004

Cardiovascular and hemodynamic effects of glucagon-like peptide-1.

scientific article

Cardiovascular consequences of metabolic syndrome.

scientific article published on 9 January 2017

Combination GLP-1 and Insulin Treatment Fails to Alter Myocardial Fuel Selection vs. Insulin Alone in Type 2 Diabetes

scientific article published on 01 September 2018

Comparison of isoflurane and α-chloralose in an anesthetized swine model of acute pulmonary embolism producing right ventricular dysfunction

scientific article

Contribution of BK(Ca) channels to local metabolic coronary vasodilation: Effects of metabolic syndrome.

scientific article

Contribution of IKCa channels to the control of coronary blood flow.

scientific article published on 18 April 2011

Contribution of adenosine A(2A) and A(2B) receptors to ischemic coronary dilation: role of K(V) and K(ATP) channels ⬇️

scientific article published on November 1, 2010

Contribution of electromechanical coupling between Kv and Ca v1.2 channels to coronary dysfunction in obesity.

scientific article

Contribution of hydrogen sulfide to the control of coronary blood flow

scientific article published on February 2014

Contribution of voltage-dependent K+ and Ca2+ channels to coronary pressure-flow autoregulation.

scientific article published on 31 March 2012

Control of coronary blood flow during exercise.

scientific article

Coronary Vasomotor Reactivity to Endothelin-1 in the Prediabetic Metabolic Syndrome

scientific article published in January 2006

Coronary arteriolar vasoconstriction to angiotensin II is augmented in prediabetic metabolic syndrome via activation of AT1 receptors.

scientific article published on 14 January 2005

Coronary blood flow regulation in the prediabetic metabolic syndrome.

scientific article published on 16 May 2003

Critical contribution of KV1 channels to the regulation of coronary blood flow

scientific article published on 5 August 2016

Disentangling the Gordian knot of local metabolic control of coronary blood flow

scientific article published on 08 November 2019

Dysfunction of cardiac ryanodine receptors in the metabolic syndrome

scientific article published on 21 June 2006

Effects of leptin on cardiovascular physiology

scientific article published on July 2007

Elevated right atrial pressure does not reduce collateral blood flow to ischemic myocardium ⬇️

scientific article published on November 1, 1997

Epicardial perivascular adipose tissue as a therapeutic target in obesity-related coronary artery disease

scientific article published in February 2012

Experimental animal models of coronary microvascular dysfunction

scientific article published on 01 March 2020

Flipped classroom model improves graduate student performance in cardiovascular, respiratory, and renal physiology.

scientific article published in December 2013

Functional contribution of P2Y1 receptors to the control of coronary blood flow.

scientific article published on 22 September 2011

Glucagon-Like Peptide 1 Receptor Activation Augments Cardiac Output and Improves Cardiac Efficiency in Obese Swine After Myocardial Infarction

scientific article published on 8 May 2017

Glucagon-like peptide-1 (7-36) but not (9-36) augments cardiac output during myocardial ischemia via a Frank-Starling mechanism.

scientific article

H2O2-induced redox-sensitive coronary vasodilation is mediated by 4-aminopyridine-sensitive K+ channels

scientific article published in November 2006

Heart of the matter: Coronary dysfunction in metabolic syndrome ⬇️

scientific article published on July 13, 2011

Hydrogen Peroxide

scientific article published in December 2006

Impaired capsaicin-induced relaxation of coronary arteries in a porcine model of the metabolic syndrome.

scientific article

Impaired cardiometabolic responses to glucagon-like peptide 1 in obesity and type 2 diabetes mellitus

scientific article published on 14 June 2013

Impaired function of coronary BK(Ca) channels in metabolic syndrome

scientific article published on 11 September 2009

Impairment of exercise hyperaemia in familial hypercholesterolaemia: complex interplay of vasodilators vs. vasoconstrictors

scientific article published on 15 April 2014

Increased lymphatic flow in the thoracic duct during manipulative intervention

scientific article published on 01 October 2005

Inhibition of sodium-glucose cotransporter-2 preserves cardiac function during regional myocardial ischemia independent of alterations in myocardial substrate utilization

scientific article published on 19 April 2019

Insulin improves cardiac contractile function and oxygen utilization efficiency during moderate ischemia without compromising myocardial energetics.

scientific article published on October 1998

Intermittent hypoxic training protects canine myocardium from infarction.

scientific article published in September 2004

Intracoronary glucagon-like peptide 1 preferentially augments glucose uptake in ischemic myocardium independent of changes in coronary flow.

scientific article published on 16 February 2012

KV7 channels contribute to paracrine, but not metabolic or ischemic, regulation of coronary vascular reactivity in swine

scientific article published on 29 January 2016

Lean and Obese Coronary Perivascular Adipose Tissue Impairs Vasodilation via Differential Inhibition of Vascular Smooth Muscle K+ Channels

scientific article published on 2 April 2015

Leptin and mechanisms of endothelial dysfunction and cardiovascular disease.

scientific article published on December 2008

Leptin augments coronary vasoconstriction and smooth muscle proliferation via a Rho-kinase-dependent pathway

scientific article

Leptin-induced endothelial dysfunction: a target for therapeutic interventions.

scientific article published on January 2014

Local metabolic hypothesis is not sufficient to explain coronary autoregulatory behavior

scientific article published on 02 August 2018

Matching coronary blood flow to myocardial oxygen consumption.

scientific article published in July 2004

Mechanisms underlying capsaicin effects in canine coronary artery: implications for coronary spasm

scientific article

Mutual reinforcement of pathophysiological host-microbe interactions in intestinal stasis models.

scientific article published on March 2017

Nitric oxide contributes to oxygen demand-supply balance in hypoperfused right ventricle.

scientific article published in December 2004

Nitric oxide contributes to right coronary vasodilation during systemic hypoxia.

scientific article published on 28 October 2004

Nitric oxide modulates right ventricular flow and oxygen consumption during norepinephrine infusion.

scientific article published in February 2002

Obesity alters molecular and functional cardiac responses to ischemia/reperfusion and glucagon-like peptide-1 receptor agonism.

scientific article published on 27 May 2016

On the record. Looking at ordinary people's tales of living with their mental illness. Interview by Alita Buttress.

scientific article published in September 2011

Periadventitial adipose tissue impairs coronary endothelial function via PKC-beta-dependent phosphorylation of nitric oxide synthase.

scientific article published on 29 May 2009

Perivascular adipose tissue and coronary vascular disease

scientific article

ROCK as a molecular bond connecting coronary microvascular and cardiac remodelling.

scientific article published in September 2017

Regulation of 130-kDa smooth muscle myosin light chain kinase expression by an intronic CArG element.

scientific article published on 22 October 2013

Regulation of Coronary Blood Flow.

scientific article published on 16 March 2017

Regulation of myocardial oxygen delivery in response to graded reductions in hematocrit: role of K+ channels.

scientific article published on 30 September 2017

Resistin impairs endothelium-dependent dilation to bradykinin, but not acetylcholine, in the coronary circulation

scientific article published in December 2006

Role of endothelin in alpha-adrenoceptor coronary vasoconstriction.

scientific article published on 9 December 2004

Sensitization of coronary alpha-adrenoceptor vasoconstriction in the prediabetic metabolic syndrome

scientific article published on 01 October 2006

Small-Group Activity to Reinforce the Impact of Valvular Defects and Heart Failure on Cardiac Pressure-Volume Relationships

scientific article published on 06 February 2018

The effect of aging on adrenergic and nonadrenergic receptor expression and responsiveness in canine skeletal muscle

scientific article published on 22 December 2011

Voltage-dependent K+ channels regulate the duration of reactive hyperemia in the canine coronary circulation.

scientific article

Withdrawal of vasoconstrictor influences in local metabolic coronary vasodilation

scientific article published on 14 July 2006

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