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List of works by Andrew Elefanty

10 Factors involved in leukaemogenesis and haemopoiesis ⬇️

scientific article published on September 1, 1997

1010 - CHARACTERIZING HOXA-EXPRESSING ENDOTHELIAL AND HAEMATOPOIETIC POPULATIONS DERIVED FROM HUMAN PLURIPOTENT STEM CELLS

scholarly article

3176 – MULTIPOTENT RAG1+ PROGENITORS EMERGE DIRECTLY FROM HEMOGENIC ENDOTHELIUM IN HUMAN PSC DERIVED HEMOPOIETIC ORGANOIDS ⬇️

scholarly article

A Cas9 Variant for Efficient Generation of Indel-Free Knockin or Gene-Corrected Human Pluripotent Stem Cells

scientific article published on 03 August 2016

A Pro-Endocrine Pancreatic Islet Transcriptional Program Established During Development Is Retained in Human Gallbladder Epithelial Cells

scientific article published on 12 January 2022

A method for genetic modification of human embryonic stem cells using electroporation

scientific article published on January 2007

A mouse carrying the green fluorescent protein gene targeted to the Pdx1 locus facilitates the study of pancreas development and function.

scientific article published in June 2006

A protocol describing the use of a recombinant protein-based, animal product-free medium (APEL) for human embryonic stem cell differentiation as spin embryoid bodies

scientific article published in January 2008

A protocol for removal of antibiotic resistance cassettes from human embryonic stem cells genetically modified by homologous recombination or transgenesis

scientific article published on 01 January 2008

A targeted NKX2.1 human embryonic stem cell reporter line enables identification of human basal forebrain derivatives.

scientific article published on March 2011

ALPK3-deficient cardiomyocytes generated from patient-derived induced pluripotent stem cells and mutant human embryonic stem cells display abnormal calcium handling and establish that ALPK3 deficiency underlies familial cardiomyopathy.

scientific article published on 22 April 2016

APELIN promotes hematopoiesis from human embryonic stem cells

scientific article published on 18 May 2012

Aberrant hematopoiesis in mice with inactivation of the gene encoding SOCS-1

scientific article published on 01 June 1999

An INSULIN-GFP/GLUCAGON-mCherry reporter line for the study of human pancreatic endocrine cell development

scientific article published on 28 September 2021

Analysis of mitochondrial function and localisation during human embryonic stem cell differentiation in vitro.

scientific article

Apoptosis and beta-cell destruction in pancreatic islets of NOD mice with spontaneous and cyclophosphamide-accelerated diabetes

scientific article published on 01 November 1998

Blood cells form from phenotypically distinct precursors during human blast colony differentiation

scientific article published in 2015

Brachyury and related Tbx proteins interact with the Mixl1 homeodomain protein and negatively regulate Mixl1 transcriptional activity

scientific article

Building better beta cells

scientific article published on 01 April 2008

CD13 and ROR2 Permit Isolation of Highly Enriched Cardiac Mesoderm from Differentiating Human Embryonic Stem Cells

scientific article published on January 2016

CD90 Marks a Mesenchymal Program in Human Thymic Epithelial Cells <i>In Vitro</i> and <i>In Vivo</i>

scientific article published on 16 March 2022

CRISPR/Cas9 gene editing of a SOX9 reporter human iPSC line to produce two TRPV4 patient heterozygous missense mutant iPSC lines, MCRIi001-A-3 (TRPV4 p.F273L) and MCRIi001-A-4 (TRPV4 p.P799L)

scientific article published on 03 August 2020

Characterization of hematopoietic progenitor cells that express the transcription factor SCL, using a lacZ "knock-in" strategy

scientific article

Defined substrates for pluripotent stem cells: are we there yet? ⬇️

scientific article published on December 1, 2010

Derivation of endothelial cells from human embryonic stem cells in fully defined medium enables identification of lysophosphatidic acid and platelet activating factor as regulators of eNOS localization

scientific article

Derivation of insulin-producing beta-cells from human pluripotent stem cells

scientific article

Differentiating embryonic stem cells pass through 'temporal windows' that mark responsiveness to exogenous and paracrine mesendoderm inducing signals

scientific article

Differentiation of human embryonic stem cells and induced pluripotent stem cells to cardiomyocytes: a methods overview

scientific article

Differentiation of human embryonic stem cells in serum-free medium reveals distinct roles for bone morphogenetic protein 4, vascular endothelial growth factor, stem cell factor, and fibroblast growth factor 2 in hematopoiesis

scientific article published on 7 June 2007

Differentiation of human embryonic stem cells to HOXA+ hemogenic vasculature that resembles the aorta-gonad-mesonephros.

scientific article published on 17 October 2016

Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells

scientific article published on May 2013

Directed differentiation of human embryonic stem cells as spin embryoid bodies and a description of the hematopoietic blast colony forming assay

scientific article published on 01 January 2008

Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidney

scientific article published on 15 December 2013

ESTOOLS, a project funded by the European Commission(FP6), gathers expertise on human embryonic stem cells in 10 countries of the European Research Area

scientific article published on 01 March 2009

Efficient Cre-mediated deletion in cardiac progenitor cells conferred by a 3'UTR-ires-Cre allele of the homeobox gene Nkx2-5.

scientific article

Efficient endoderm induction from human pluripotent stem cells by logically directing signals controlling lineage bifurcations.

scientific article

Efficient generation of NKX6-1+ pancreatic progenitors from multiple human pluripotent stem cell lines

scientific article

Efficient generation of adipocytes in a dish ⬇️

scientific article published on 02 February 2012

Efficiently Specified Ventral Midbrain Dopamine Neurons from Human Pluripotent Stem Cells Under Xeno-Free Conditions Restore Motor Deficits in Parkinsonian Rodents.

scientific article

Endocrine cells develop within pancreatic bud-like structures derived from mouse ES cells differentiated in response to BMP4 and retinoic acid

scientific article published on 3 August 2007

Enforced Expression of HOXB4 in Human Embryonic Stem Cells Enhances the Production of Hematopoietic Progenitors but Has No Effect on the Maturation of Red Blood Cells.

scientific article published on 28 June 2016

Enforced expression of Mixl1 during mouse ES cell differentiation suppresses hematopoietic mesoderm and promotes endoderm formation

scientific journal article

Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system

scientific article (publication date: 21 November 2016)

ErythRED, a hESC line enabling identification of erythroid cells

scientific article

Expansion of human embryonic stem cells in vitro

scientific article published on 01 May 2008

Expression from a betageo gene trap in the Slain1 gene locus is predominantly associated with the developing nervous system.

scientific article published on January 2010

Expression of BCR – ABL in M1 myeloid leukemia cells induces differentiation without arresting proliferation

scientific article published on 01 January 1999

Expression of RUNX1-ETO Rapidly Alters the Chromatin Landscape and Growth of Early Human Myeloid Precursor Cells

scientific article published on 01 May 2020

Expression pattern of the stem cell leukaemia gene in the CNS of the embryonic and adult mouse.

scientific article

FOXN1 (GFP/w) reporter hESCs enable identification of integrin-β4, HLA-DR, and EpCAM as markers of human PSC-derived FOXN1(+) thymic epithelial progenitors.

scientific article

Five years of Stem Cell Research — Reflections on progress in the field ⬇️

scientific article published on November 1, 2012

Forced aggregation of defined numbers of human embryonic stem cells into embryoid bodies fosters robust, reproducible hematopoietic differentiation.

scientific article published on 24 May 2005

Fourier transform infrared microspectroscopy identifies early lineage commitment in differentiating human embryonic stem cells

scientific article published on 2 December 2009

Fourier transform infrared microspectroscopy reveals that tissue culture conditions affect the macromolecular phenotype of human embryonic stem cells

scientific article published on 7 June 2013

Fourier transform infrared microspectroscopy reveals unique phenotypes for human embryonic and induced pluripotent stem cell lines and their progeny.

scientific article published on 25 April 2013

Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development.

scientific article published on May 2013

Fusion of Regionally Specified hPSC-Derived Organoids Models Human Brain Development and Interneuron Migration

scientific article published on 26 July 2017

GAPTrap: A Simple Expression System for Pluripotent Stem Cells and Their Derivatives

scientific article published on September 2016

Generating GABAergic cerebral cortical interneurons from mouse and human embryonic stem cells.

scientific article published on 13 December 2011

Generation of RAB39B knockout isogenic human embryonic stem cell lines to model RAB39B-mediated Parkinson's disease.

scientific article published on 21 February 2018

Generation of a SOX9-tdTomato reporter human iPSC line, MCRIi001-A-2, using CRISPR/Cas9 editing

scientific article published on 19 December 2019

Generation of a heterozygous COL1A1 (c.3969_3970insT) osteogenesis imperfecta mutation human iPSC line, MCRIi001-A-1, using CRISPR/Cas9 editing

scientific article published on 23 April 2019

Generation of a heterozygous COL2A1 (p.R989C) spondyloepiphyseal dysplasia congenita mutation iPSC line, MCRIi001-B, using CRISPR/Cas9 gene editing

scientific article published on 11 May 2020

Generation of human embryonic stem cell reporter knock-in lines by homologous recombination

scientific article published on 01 November 2009

Generation of human female reproductive tract epithelium from human embryonic stem cells.

scientific article

Generation of iPSC lines from peripheral blood mononuclear cells from 5 healthy adults

scientific article published on 27 December 2018

Generation of megakaryocytic progenitors from human embryonic stem cells in a feeder- and serum-free medium.

scientific article

Human acquired naevi are clonal

scientific article published on 01 December 1998

Human chondrogenic paraxial mesoderm, directed specification and prospective isolation from pluripotent stem cells

scientific article published on 13 June 2012

Human definitive haemogenic endothelium and arterial vascular endothelium represent distinct lineages

scientific article

Human embryonic stem cell derived mesenchymal progenitors express cardiac markers but do not form contractile cardiomyocytes.

scientific article

Human haematopoietic stem cell development: from the embryo to the dish

scientific article

Human yolk sac-like haematopoiesis generates RUNX1- and GFI1/1B-dependent blood and SOX17-positive endothelium

scientific article published on 07 October 2020

In the absence of apoptosis, myeloid cells arrest when deprived of growth factor, but remain viable by consuming extracellular glucose

scientific article published on 15 February 2019

In this issue...

scientific article published on 01 November 2007

Inaugural issue of Stem Cell Research

scientific article published on 01 October 2007

Induced pluripotent stem cell macrophages present antigen to proinsulin-specific T cell receptors from donor-matched islet-infiltrating T cells in type 1 diabetes

scientific article published on 12 September 2019

Inhibition of DYRK1A disrupts neural lineage specification in human pluripotent stem cells

scientific article published on 8 September 2017

Integrin αvβ5 heterodimer is a specific marker of human pancreatic beta cells

scientific article published on 15 April 2021

Isolation of human lymphatic endothelial cells by multi-parameter fluorescence-activated cell sorting

scientific article

Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1.

scientific article published on November 1998

Long-Term Maintenance of Human Pluripotent Stem Cells on cRGDfK-Presenting Synthetic Surfaces.

scientific article published on 15 January 2018

Magnetic Resonance Imaging of Iron Oxide-Labeled Human Embryonic Stem Cell-Derived Cardiac Progenitors

scientific article

Mapping human haematopoietic stem cells from haemogenic endothelium to birth

scientific article published on 13 April 2022

Microbioreactor arrays for full factorial screening of exogenous and paracrine factors in human embryonic stem cell differentiation.

scientific article

Mimicry of embryonic circulation enhances the hoxa hemogenic niche and human blood development

scientific article published in 2022

Mixl1 and oct4 proteins are transiently co-expressed in differentiating mouse and human embryonic stem cells.

scientific article published in December 2005

Mixl1 is required for axial mesendoderm morphogenesis and patterning in the murine embryo

scientific journal article

Multipotent RAG1+ progenitors emerge directly from haemogenic endothelium in human pluripotent stem cell-derived haematopoietic organoids

scientific article published on 06 January 2020

NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network

scientific article published on 10 April 2018

NKX2-5(eGFP/w) hESCs for isolation of human cardiac progenitors and cardiomyocytes.

scientific article published on 23 October 2011

On the streets of San Francisco: highlights from the ISSCR Annual Meeting 2010.

scientific article published in October 2010

One final word…

scientific article published on 27 December 2014

Overcoming Monocarboxylate Transporter 8 (MCT8)-Deficiency to Promote Human Oligodendrocyte Differentiation and Myelination

scientific article published on 19 October 2017

PGC-1α and reactive oxygen species regulate human embryonic stem cell-derived cardiomyocyte function.

scientific article published on 12 December 2013

Pancreas differentiation of mouse ES cells

scientific article published in August 2007

Pancreatic differentiation from pluripotent stem cells: tweaking the system.

scientific article

Pdgfrα and Flk1 are direct target genes of Mixl1 in differentiating embryonic stem cells.

scientific article

Productive Infection of Human Embryonic Stem Cell-Derived NKX2.1+ Respiratory Progenitors with Human Rhinovirus.

scientific article published on 14 April 2015

RUNX1 AND GROUP F SOX GENES ARE REQUIRED AT DISTINCT STAGES FOR HUMAN HAEMATOPOIETIC DEVELOPMENT

scholarly article

RUNX1-ETO RAPIDLY REPROGRAMS THE EPIGENETIC LANDSCAPE IN HUMAN EMBRYONIC DEFINITIVE HAEMATOPOIETIC PROGENITORS

scholarly article

RUNX1c Regulates Hematopoietic Differentiation of Human Pluripotent Stem Cells Possibly in Cooperation with Proinflammatory Signaling.

scientific article published on 4 September 2017

Regulatory networks specifying cortical interneurons from human embryonic stem cells reveal roles for CHD2 in interneuron development

scientific article published on 11 December 2017

Reshaping pluripotent stem cells

scientific article published on 01 September 2009

Retinoic acid induces Pdx1-positive endoderm in differentiating mouse embryonic stem cells

scientific article

SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells. ⬇️

scientific article published on 23 October 2011

SIRPA, VCAM1 and CD34 identify discrete lineages during early human cardiovascular development.

scientific article published on 4 May 2014

Simultaneous Reprogramming and Gene Correction of Patient Fibroblasts

scientific article

Spatio-temporal re-organization of replication foci accompanies replication domain consolidation during human pluripotent stem cell lineage specification.

scientific article published on 19 July 2016

Stage-specific signaling through TGFβ family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells.

scientific article published on 26 January 2011

Stem Cell Research. In this issue.

scientific article

Stem cells in biology, tissue engineering and medicine: the leading edge keeps moving.

scientific article

THE ROLE OF SHEAR STRESS IN THE GENERATION OF DEFINITIVE HAEMATOPOIETIC LINEAGES AND ARTERIAL VASCULATURE FROM HUMAN PLURIPOTENT STEM CELLS AT THE SINGLE-CELL LEVEL

scholarly article

THE ROLE OF VENTX HOMEOBOX GENE DURING HUMAN HAEMATOPOIETIC DEVELOPMENT

scholarly article

Targeting a GFP reporter gene to the MIXL1 locus of human embryonic stem cells identifies human primitive streak-like cells and enables isolation of primitive hematopoietic precursors.

scientific article published on 21 November 2007

Temporal restriction of pancreatic branching competence during embryogenesis is mirrored in differentiating embryonic stem cells

scientific article published on 16 December 2011

The Mix family of homeobox genes--key regulators of mesendoderm formation during vertebrate development.

scientific article published on 08 May 2012

The characterisation of pluripotent and multipotent stem cells using Fourier transform infrared microspectroscopy.

scientific article published on 26 August 2013

The critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S12

scientific journal article

The hESC line Envy expresses high levels of GFP in all differentiated progeny.

scientific article

The level of the tissue‐specific factor GATA‐1 affects the cell‐cycle machinery ⬇️

scientific article published on February 1, 1997

The primitive streak gene Mixl1 is required for efficient haematopoiesis and BMP4-induced ventral mesoderm patterning in differentiating ES cells

scientific article

The role of cardiac transcription factor NKX2-5 in regulating the human cardiac miRNAome

scientific article published on 04 November 2019

The use of simultaneous reprogramming and gene correction to generate an osteogenesis imperfecta patient COL1A1 c. 3936 G>T iPSC line and an isogenic control iPSC line

scientific article published on 04 May 2019

This review explores the various stem and progenitor cell populations that are resident in the microvasculature, endothelium, and vessel walls

scientific article published on 01 January 2009

Transcriptional profiling of mouse and human ES cells identifies SLAIN1, a novel stem cell gene.

scientific article

WNT3A promotes hematopoietic or mesenchymal differentiation from hESCs depending on the time of exposure

scientific article published on 04 June 2013

WNT9A Is a Conserved Regulator of Hematopoietic Stem and Progenitor Cell Development

scientific article

β-cell regeneration and differentiation: how close are we to the 'holy grail'?

scientific article

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