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List of works by Hsin-Chen Lee

7-Ketocholesterol induces P-glycoprotein through PI3K/mTOR signaling in hepatoma cells

scientific article

A novel mechanism of coenzyme Q10 protects against human endothelial cells from oxidative stress-induced injury by modulating NO-related pathways

scientific article published on 17 June 2011

Activated Integrated Stress Response Induced by Salubrinal Promotes Cisplatin Resistance in Human Gastric Cancer Cells via Enhanced xCT Expression and Glutathione Biosynthesis

scientific article published on 29 October 2018

Aging- and smoking-associated alteration in the relative content of mitochondrial DNA in human lung

scientific article published on 01 December 1998

Ascorbic acid mitigates the myocardial injury after cardiac arrest and electrical shock

scientific article published on 28 September 2011

Bioactivity and Gene Expression Profiles of hiPSC-generated Retinal Ganglion Cells in MT-ND4 Mutated Leber's Hereditary Optic Neuropathy.

scientific article published on 20 January 2018

CHAC1 degradation of glutathione enhances cystine-starvation-induced necroptosis and ferroptosis in human triple negative breast cancer cells via the GCN2-eIF2α-ATF4 pathway.

scientific article published on 9 December 2017

Combined effect of honokiol and rosiglitazone on cell growth inhibition through enhanced G0/G1 phase arrest in hepatoma cells

scientific article

Concurrent increase of oxidative DNA damage and lipid peroxidation together with mitochondrial DNA mutation in human lung tissues during aging--smoking enhances oxidative stress on the aged tissues

scientific article published on 01 February 1999

Curcumin induces the apoptosis of human monocytic leukemia THP-1 cells via the activation of JNK/ERK Pathways ⬇️

scientific article published on March 24, 2012

DNAJA3/Tid1 Is Required for Mitochondrial DNA Maintenance and Regulates Migration and Invasion of Human Gastric Cancer Cells

scientific article published on 20 November 2020

Downregulation of tumor suppressor MBP-1 by microRNA-363 in gastric carcinogenesis.

scientific article published on 23 August 2013

Energy metabolism determines the sensitivity of human hepatocellular carcinoma cells to mitochondrial inhibitors and biguanide drugs.

scientific article published on 30 June 2015

Enhanced oxidative stress and aberrant mitochondrial biogenesis in human neuroblastoma SH-SY5Y cells during methamphetamine induced apoptosis.

scientific article

Exclusive homoplasmic 11778 mutation in mitochondrial DNA of Chinese patients with Leber's hereditary optic neuropathy

scientific article published on 01 May 1999

Functional dysconnection in the prefrontal-amygdala circuitry in unaffected siblings of patients with bipolar I disorder.

scientific article published on 20 August 2015

Gene expression profiling of peripheral blood leukocytes identifies and validates ABCB1 as a novel biomarker for Alzheimer's disease.

scientific article

Generation of two isogenic human induced pluripotent stem cell lines from a 15 year-old female patient with MERRF syndrome and A8344G mutation of mitochondrial DNA

scientific article published on 28 May 2018

Impaired ROS Scavenging System in Human Induced Pluripotent Stem Cells Generated from Patients with MERRF Syndrome

scientific article published on 30 March 2016

Involvement of oxidative stress-activated JNK signaling in the methamphetamine-induced cell death of human SH-SY5Y cells.

scientific article

MAOA-a novel decision maker of apoptosis and autophagy in hormone refractory neuroendocrine prostate cancer cells.

scientific article

Melatonin attenuates kainic acid-induced neurotoxicity in mouse hippocampus via inhibition of autophagy and α-synuclein aggregation.

scientific article

Mevalonate Pathway Enzyme HMGCS1 Contributes to Gastric Cancer Progression

scientific article published on 27 April 2020

MicroRNA-23a/27a/24-2 cluster promotes gastric cancer cell proliferation synergistically.

scientific article published on 7 June 2018

Mitochondria and aging.

scientific article published on January 2012

Mitochondria are an essential mediator of nitric oxide/cyclic guanosine 3',5'-monophosphate blocking of glucose depletion induced cytotoxicity in human HepG2 cells.

scientific article published on September 2007

Mitochondrial DNA alterations and mitochondrial dysfunction in the progression of hepatocellular carcinoma

scientific article

Mitochondrial DNA content as a potential marker to predict response to anthracycline in breast cancer patients.

scientific article published on 12 April 2010

Mitochondrial DNA instability and metabolic shift in human cancers.

scientific article published on 23 February 2009

Mitochondrial DNA mutations and mitochondrial DNA depletion in gastric cancer

scientific article

Mitochondrial DNA mutations in light-associated skin tumors.

scientific article

Mitochondrial alterations, cellular response to oxidative stress and defective degradation of proteins in aging.

scientific article

Mitochondrial biogenesis and mitochondrial DNA maintenance of mammalian cells under oxidative stress.

scientific article

Mitochondrial dysfunction enhances cisplatin resistance in human gastric cancer cells via the ROS-activated GCN2-eIF2α-ATF4-xCT pathway.

scientific article published on 30 September 2016

Mitochondrial dysfunction promotes cell migration via reactive oxygen species-enhanced β5-integrin expression in human gastric cancer SC-M1 cells

scientific article published on April 26, 2012

Mitochondrial dysfunction-induced amphiregulin upregulation mediates chemo-resistance and cell migration in HepG2 cells.

scientific article published on May 2009

Mitochondrial genome instability and mtDNA depletion in human cancers

scientific article published on 01 May 2005

Mucolytic Agents and Statins Use is Associated with a Lower Risk of Acute Exacerbations in Patients with Bronchiectasis-Chronic Obstructive Pulmonary Disease Overlap

scientific article published on 04 December 2018

Mutation and oxidative damage of mitochondrial DNA and defective turnover of mitochondria in human aging

scientific article published on October 1, 1997

Notch1 pathway-mediated microRNA-151-5p promotes gastric cancer progression.

scientific article published on 13 May 2016

Oxidative damage and mutation to mitochondrial DNA and age-dependent decline of mitochondrial respiratory function

scientific article published on 01 November 1998

Oxidative stress, mitochondrial DNA mutation, and impairment of antioxidant enzymes in aging.

scientific article

PGC-1α Mediates Differentiation of Mesenchymal Stem Cells to Brown Adipose Cells ⬇️

scientific article published on August 5, 2011

Peripheral and central glucose utilizations modulated by mitochondrial DNA 10398A in bipolar disorder.

scientific article

Polymorphisms of estrogen-metabolizing genes and risk of hepatocellular carcinoma in Taiwan females.

scientific article published in August 2004

ROS Mediate xCT-Dependent Cell Death in Human Breast Cancer Cells under Glucose Deprivation

scientific article published on 01 July 2020

ROS and Oxidative Stress in Stem Cells

scientific article published on 6 September 2017

Role of mitochondrial dysfunction in cancer progression

scientific article

Role of the mitochondrial stress response in human cancer progression

scientific article published on 23 April 2020

SIRT3 expression as a biomarker for better prognosis in gastric cancer

scientific article published in April 2014

Salubrinal Enhances Cancer Cell Death during Glucose Deprivation through the Upregulation of xCT and Mitochondrial Oxidative Stress

scientific article published in 2021

Somatic alterations in mitochondrial DNA and mitochondrial dysfunction in gastric cancer progression

scientific article published on April 2014

Somatic mutations of mitochondrial DNA in aging and cancer progression.

scientific article published on 08 September 2010

Somatic mutations of mitochondrial genome in hepatocellular carcinoma

scientific article

Somatic mutations of the mitochondrial genome in human breast cancers ⬇️

scientific article published on July 11, 2011

Suppressor of cytokine signaling 6 (SOCS6) promotes mitochondrial fission via regulating DRP1 translocation.

scientific article

Targeting aerobic glycolysis and HIF-1alpha expression enhance imiquimod-induced apoptosis in cancer cells.

scientific article

The reciprocal regulation loop of Notch2 pathway and miR-23b in controlling gastric carcinogenesis

scientific article

Zoledronic acid-induced cytotoxicity through endoplasmic reticulum stress triggered REDD1-mTOR pathway in breast cancer cells.

scientific article published on September 2013

miR-151-3p Targets TWIST1 to Repress Migration of Human Breast Cancer Cells

scientific article

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