List of works - Shohei Sakuda

A bitter melon extract inhibits the P-glycoprotein activity in intestinal Caco-2 cells: monoglyceride as an active compound.

scientific article

A class III chitinase without disulfide bonds from the fern, Pteris ryukyuensis: crystal structure and ligand-binding studies

scientific article

A comparison of pharmacokinetics between humans and monkeys

scientific article published on 12 November 2009

A cryptic antibiotic triggered by monensin

scientific article published on 27 July 2011

A novel highly acidic polysaccharide with inhibitory activity on calcification from the calcified scale "coccolith" of a coccolithophorid alga, Pleurochrysis haptonemofera

scientific article published on 19 April 2007

Absolute structure of prunustatin A, a novel GRP78 molecular chaperone down-regulator

scientific article published on 21 September 2007

Assamicin I and II, novel triterpenoid saponins with insulin-like activity from Aesculus assamica Griff.

scientific article published on March 2002

Astaxanthin dirhamnoside, a new astaxanthin derivative produced by a radio-tolerant bacterium, Sphingomonas astaxanthinifaciens. ⬇️

scientific article published on 26 June 2009

Chitinase inhibition promotes atherosclerosis in hyperlipidemic mice.

scientific article published on 15 May 2013

Chitinase inhibitor allosamidin is a signal molecule for chitinase production in its producing Streptomyces I. Analysis of the chitinase whose production is promoted by allosamidin and growth accelerating activity of allosamidin.

scientific article published in July 2006

Chitinase inhibitor allosamidin is a signal molecule for chitinase production in its producing Streptomyces II. Mechanism for regulation of chitinase production by allosamidin through a two-component regulatory system

scientific article published on 01 July 2006

Chronic treatment with novel GPR40 agonists improve whole-body glucose metabolism based on the glucose-dependent insulin secretion.

scientific article published on 12 July 2013

Comparative activities of glutathione-S-transferase and dialdehyde reductase toward aflatoxin B1 in livers of experimental and farm animals.

scientific article published in August 2005

Conversion from arenes having a benzene ring to those having a picolinic acid by simple growing cell reactions using Escherichia coli that expressed the six bacterial genes involved in biphenyl catabolism.

scientific article published in November 2004

Correlation of ATP citrate lyase and acetyl CoA levels with trichothecene production in Fusarium graminearum.

scientific article

Crystal defects induced by chitin and chitinolytic enzymes in the prismatic layer of Pinctada fucata.

scientific article published on 16 May 2017

Crystal structures and inhibitor binding properties of plant class V chitinases: the cycad enzyme exhibits unique structural and functional features

scientific article

Development of a genetic system in chitinase-producing streptomyces and the application of an allosamidin-insensitive chitinase gene to homologous overexpression.

scientific article published in March 2004

Dillapiol and Apiol as specific inhibitors of the biosynthesis of aflatoxin G1 in Aspergillus parasiticus

scientific article published on 07 September 2007

Dioctatin A is a strong inhibitor of aflatoxin production by Aspergillus parasiticus

scientific article published on 01 August 2007

Effect of demethylation on the chitinase inhibitory activity of allosamidin ⬇️

scientific article published on January 1, 1997

Endocrocin and its derivatives from the Japanese mealybug Planococcus kraunhiae. ⬇️

scientific article published on 22 April 2011

Enhancement of trichothecene production in Fusarium graminearum by cobalt chloride

scientific article published on 07 February 2011

Exploring an Artificial Metabolic Route in Fusarium sporotrichioides: Production and Characterization of 7-Hydroxy T-2 Toxin

scientific article published on 26 March 2018

Expression of ephrin-B1 in hepatocellular carcinoma: possible involvement in neovascularization.

scientific article published on December 2003

Glycolytic intermediates induce amorphous calcium carbonate formation in crustaceans.

scientific article

Identification of chitin in the prismatic layer of the shell and a chitin synthase gene from the Japanese pearl oyster, Pinctada fucata

article

Identification of ligament intra-crystalline peptide (LICP) from the hinge ligament of the bivalve, Pinctada fucata

scientific article published on 16 October 2014

Identification of the allosamidin-releasing factor in allosamidin-producing Streptomyces ⬇️

scientific article

Inhibition of Aflatoxin Production by Paraquat and External Superoxide Dismutase in Aspergillus flavus

scientific article published on 12 February 2019

Inhibition of the DNA polymerase and RNase H activities of HIV-1 reverse transcriptase and HIV-1 replication by Brasenia schreberi (Junsai) and Petasites japonicus (Fuki) components.

scientific article published on 8 February 2015

Inhibitory Activities of Alkyl Syringates and Related Compounds on Aflatoxin Production.

scientific article published on 7 June 2016

Inhibitory activity of blasticidin A, a strong aflatoxin production inhibitor, on protein synthesis of yeast: selective inhibition of aflatoxin production by protein synthesis inhibitors.

scientific article published on 23 April 2010

Inhibitory effect of a bitter melon extract on the P-glycoprotein activity in intestinal Caco-2 cells. ⬇️

scientific article published on 6 September 2004

Inhibitory effects of Satureja hortensis L. essential oil on growth and aflatoxin production by Aspergillus parasiticus.

scientific article

Inhibitory effects of respiration inhibitors on aflatoxin production.

scientific article

Intracellular superoxide level controlled by manganese superoxide dismutases affects trichothecene production in Fusarium graminearum

scientific article published on 5 October 2017

Isolation of Abikoviromycin and Dihydroabikoviromycin as Inhibitors of Polyketide Synthase Involved in Melanin Biosynthesis by Colletotrichum lagenarium ⬇️

scientific article published on 01 March 2012

Isolation of elemental sulfur as a self-growth-inhibiting substance produced by Legionella pneumophila.

scientific article published on October 2002

Isolation of methyl syringate as a specific aflatoxin production inhibitor from the essential oil of Betula alba and aflatoxin production inhibitory activities of its related compounds

scientific article published on 02 December 2011

Kinetic analysis of a chitinase from red sea bream, Pagrus major.

scientific article

Marked species differences in the bioavailability of midazolam in cynomolgus monkeys and humans.

scientific article published in April 2006

Molecular Mechanism of Peptide-Specific Pheromone Signaling in Enterococcus faecalis : Functions of Pheromone Receptor TraA and Pheromone-Binding Protein TraC Encoded by Plasmid pPD1 ⬇️

scientific article published on February 1, 1998

Molecular cloning and functional analysis of chitinases in the fresh water snail, Lymnaea stagnalis.

scientific article published on 3 March 2016

Morphological Changes in Insect BM-N4 Cells Induced by Nocardamine.

scientific article published in January 1998

NF-kappaB activation in non-parenchymal liver cells after partial hepatectomy in rats: possible involvement in expression of heparin-binding epidermal growth factor-like growth factor.

scientific article

New metabolic pathway for converting blasticidin S in Aspergillus flavus and inhibitory activity of aflatoxin production by blasticidin S metabolites.

scientific article published on 12 August 2013

Novel benzene ring biosynthesis from C(3) and C(4) primary metabolites by two enzymes.

scientific article published on 26 September 2006

Novel biological activities of allosamidins.

scientific article published on 13 June 2013

Precocene II, a Trichothecene Production Inhibitor, Binds to Voltage-Dependent Anion Channel and Increases the Superoxide Level in Mitochondria of Fusarium graminearum.

scientific article published on 6 August 2015

Preparation of biotinylated allosamidins with strong chitinase inhibitory activities.

scientific article published in November 1998

Prevention of aflatoxin contamination by a soil bacterium of Stenotrophomonas sp. that produces aflatoxin production inhibitors.

scientific article published on 28 February 2013

Promomycin, a polyether promoting antibiotic production in Streptomyces spp. ⬇️

scientific article published on 23 June 2010

Prunustatin A, a novel GRP78 molecular chaperone down-regulator isolated from Streptomyces violaceoniger.

scientific article

Search for aflatoxin and trichothecene production inhibitors and analysis of their modes of action.

scientific article published on 17 September 2015

Spiroethers of German chamomile inhibit production of aflatoxin G and trichothecene mycotoxin by inhibiting cytochrome P450 monooxygenases involved in their biosynthesis.

scientific article published on 19 May 2008

Structural and Thermodynamic Signatures of Ligand Binding to the Enigmatic Chitinase D of Serratia proteamaculans

scientific article published on 04 March 2019

Structural and functional analyses of a TIMP and MMP in the ligament of Pinctada fucata.

scientific article published on 28 July 2017

Structural and functional analyses of calcium ion response factors in the mantle of Pinctada fucata

scientific article published on 17 August 2018

Structural determination of a nivalenol glucoside and development of an analytical method for the simultaneous determination of nivalenol and deoxynivalenol, and their glucosides, in wheat

scientific article published on 24 January 2014

Structures and biosynthesis of aflastatins: novel inhibitors of aflatoxin production by Aspergillus parasiticus ⬇️

scientific article published on 01 November 1998

Synthesis of CdSe Quantum Dots Using Fusarium oxysporum.

scientific article published on 20 October 2016

Targeting AMCase reduces esophageal eosinophilic inflammation and remodeling in a mouse model of egg induced eosinophilic esophagitis.

scientific article

The Mode of Action of Cyclo(l-Ala-l-Pro) in Inhibiting Aflatoxin Production of Aspergillus flavus.

scientific article published on 12 July 2017

Transglycosylation reaction catalyzed by a class V chitinase from cycad, Cycas revoluta: a study involving site-directed mutagenesis, HPLC, and real-time ESI-MS.

scientific article published on 29 October 2009

Two-way traffic of glycoside hydrolase family 18 processive chitinases on crystalline chitin.

scientific article published on 4 June 2014

β-1,3-Glucanases and chitinases participate in the stress-related defence mechanisms that are possibly connected with modulation of arabinogalactan proteins (AGP) required for the androgenesis initiation in rye (Secale cereale L.).

scientific article published on 07 October 2020

List of works by Shohei Sakuda

A bitter melon extract inhibits the P-glycoprotein activity in intestinal Caco-2 cells: monoglyceride as an active compound.

A class III chitinase without disulfide bonds from the fern, Pteris ryukyuensis: crystal structure and ligand-binding studies

A comparison of pharmacokinetics between humans and monkeys

A cryptic antibiotic triggered by monensin

A novel highly acidic polysaccharide with inhibitory activity on calcification from the calcified scale "coccolith" of a coccolithophorid alga, Pleurochrysis haptonemofera

Absolute structure of prunustatin A, a novel GRP78 molecular chaperone down-regulator

Assamicin I and II, novel triterpenoid saponins with insulin-like activity from Aesculus assamica Griff.

Astaxanthin dirhamnoside, a new astaxanthin derivative produced by a radio-tolerant bacterium, Sphingomonas astaxanthinifaciens. ⬇️

Chitinase inhibition promotes atherosclerosis in hyperlipidemic mice.

Chitinase inhibitor allosamidin is a signal molecule for chitinase production in its producing Streptomyces I. Analysis of the chitinase whose production is promoted by allosamidin and growth accelerating activity of allosamidin.

Chitinase inhibitor allosamidin is a signal molecule for chitinase production in its producing Streptomyces II. Mechanism for regulation of chitinase production by allosamidin through a two-component regulatory system

Chronic treatment with novel GPR40 agonists improve whole-body glucose metabolism based on the glucose-dependent insulin secretion.

Comparative activities of glutathione-S-transferase and dialdehyde reductase toward aflatoxin B1 in livers of experimental and farm animals.

Conversion from arenes having a benzene ring to those having a picolinic acid by simple growing cell reactions using Escherichia coli that expressed the six bacterial genes involved in biphenyl catabolism.

Correlation of ATP citrate lyase and acetyl CoA levels with trichothecene production in Fusarium graminearum.

Crystal defects induced by chitin and chitinolytic enzymes in the prismatic layer of Pinctada fucata.

Crystal structures and inhibitor binding properties of plant class V chitinases: the cycad enzyme exhibits unique structural and functional features

Development of a genetic system in chitinase-producing streptomyces and the application of an allosamidin-insensitive chitinase gene to homologous overexpression.

Dillapiol and Apiol as specific inhibitors of the biosynthesis of aflatoxin G1 in Aspergillus parasiticus

Dioctatin A is a strong inhibitor of aflatoxin production by Aspergillus parasiticus

Effect of demethylation on the chitinase inhibitory activity of allosamidin ⬇️

Endocrocin and its derivatives from the Japanese mealybug Planococcus kraunhiae. ⬇️

Enhancement of trichothecene production in Fusarium graminearum by cobalt chloride

Exploring an Artificial Metabolic Route in Fusarium sporotrichioides: Production and Characterization of 7-Hydroxy T-2 Toxin

Expression of ephrin-B1 in hepatocellular carcinoma: possible involvement in neovascularization.

Glycolytic intermediates induce amorphous calcium carbonate formation in crustaceans.

Identification of chitin in the prismatic layer of the shell and a chitin synthase gene from the Japanese pearl oyster, Pinctada fucata

Identification of ligament intra-crystalline peptide (LICP) from the hinge ligament of the bivalve, Pinctada fucata

Identification of the allosamidin-releasing factor in allosamidin-producing Streptomyces ⬇️

Inhibition of Aflatoxin Production by Paraquat and External Superoxide Dismutase in Aspergillus flavus

Inhibition of the DNA polymerase and RNase H activities of HIV-1 reverse transcriptase and HIV-1 replication by Brasenia schreberi (Junsai) and Petasites japonicus (Fuki) components.

Inhibitory Activities of Alkyl Syringates and Related Compounds on Aflatoxin Production.

Inhibitory activity of blasticidin A, a strong aflatoxin production inhibitor, on protein synthesis of yeast: selective inhibition of aflatoxin production by protein synthesis inhibitors.

Inhibitory effect of a bitter melon extract on the P-glycoprotein activity in intestinal Caco-2 cells. ⬇️

Inhibitory effects of Satureja hortensis L. essential oil on growth and aflatoxin production by Aspergillus parasiticus.

Inhibitory effects of respiration inhibitors on aflatoxin production.

Intracellular superoxide level controlled by manganese superoxide dismutases affects trichothecene production in Fusarium graminearum

Isolation of Abikoviromycin and Dihydroabikoviromycin as Inhibitors of Polyketide Synthase Involved in Melanin Biosynthesis by Colletotrichum lagenarium ⬇️

Isolation of elemental sulfur as a self-growth-inhibiting substance produced by Legionella pneumophila.

Isolation of methyl syringate as a specific aflatoxin production inhibitor from the essential oil of Betula alba and aflatoxin production inhibitory activities of its related compounds

Kinetic analysis of a chitinase from red sea bream, Pagrus major.

Marked species differences in the bioavailability of midazolam in cynomolgus monkeys and humans.

Molecular Mechanism of Peptide-Specific Pheromone Signaling in Enterococcus faecalis : Functions of Pheromone Receptor TraA and Pheromone-Binding Protein TraC Encoded by Plasmid pPD1 ⬇️

Molecular cloning and functional analysis of chitinases in the fresh water snail, Lymnaea stagnalis.

Morphological Changes in Insect BM-N4 Cells Induced by Nocardamine.

NF-kappaB activation in non-parenchymal liver cells after partial hepatectomy in rats: possible involvement in expression of heparin-binding epidermal growth factor-like growth factor.

New metabolic pathway for converting blasticidin S in Aspergillus flavus and inhibitory activity of aflatoxin production by blasticidin S metabolites.

Novel benzene ring biosynthesis from C(3) and C(4) primary metabolites by two enzymes.

Novel biological activities of allosamidins.

Precocene II, a Trichothecene Production Inhibitor, Binds to Voltage-Dependent Anion Channel and Increases the Superoxide Level in Mitochondria of Fusarium graminearum.

Preparation of biotinylated allosamidins with strong chitinase inhibitory activities.

Prevention of aflatoxin contamination by a soil bacterium of Stenotrophomonas sp. that produces aflatoxin production inhibitors.

Promomycin, a polyether promoting antibiotic production in Streptomyces spp. ⬇️

Prunustatin A, a novel GRP78 molecular chaperone down-regulator isolated from Streptomyces violaceoniger.

Search for aflatoxin and trichothecene production inhibitors and analysis of their modes of action.

Spiroethers of German chamomile inhibit production of aflatoxin G and trichothecene mycotoxin by inhibiting cytochrome P450 monooxygenases involved in their biosynthesis.

Structural and Thermodynamic Signatures of Ligand Binding to the Enigmatic Chitinase D of Serratia proteamaculans

Structural and functional analyses of a TIMP and MMP in the ligament of Pinctada fucata.

Structural and functional analyses of calcium ion response factors in the mantle of Pinctada fucata

Structural determination of a nivalenol glucoside and development of an analytical method for the simultaneous determination of nivalenol and deoxynivalenol, and their glucosides, in wheat

Structures and biosynthesis of aflastatins: novel inhibitors of aflatoxin production by Aspergillus parasiticus ⬇️

Synthesis of CdSe Quantum Dots Using Fusarium oxysporum.

Targeting AMCase reduces esophageal eosinophilic inflammation and remodeling in a mouse model of egg induced eosinophilic esophagitis.

The Mode of Action of Cyclo(l-Ala-l-Pro) in Inhibiting Aflatoxin Production of Aspergillus flavus.

Transglycosylation reaction catalyzed by a class V chitinase from cycad, Cycas revoluta: a study involving site-directed mutagenesis, HPLC, and real-time ESI-MS.

Two-way traffic of glycoside hydrolase family 18 processive chitinases on crystalline chitin.

β-1,3-Glucanases and chitinases participate in the stress-related defence mechanisms that are possibly connected with modulation of arabinogalactan proteins (AGP) required for the androgenesis initiation in rye (Secale cereale L.).