List of works by Marianne Boes

A critical role of natural immunoglobulin M in immediate defense against systemic bacterial infection

scientific article

A dominant activating RAC2 variant associated with immunodeficiency and pulmonary disease

scientific article published on 02 August 2019

A human monoclonal immunoglobulin M reduces bacteremia and inflammation in a mouse model of systemic pneumococcal infection

scientific article

A novel FcγRIIa Q27W gene variant is associated with common variable immune deficiency through defective FcγRIIa downstream signaling.

scientific article published on 19 September 2014

A novel human STAT3 mutation presents with autoimmunity involving Th17 hyperactivation.

scientific article

A novel mutation in NLRC4 in a large pedigree with an anakinra responsive autoinflammatory disease.

scientific article

AID-/-mus-/- mice are agammaglobulinemic and fail to maintain B220-CD138+ plasma cells

scientific article published on 01 February 2007

Adipocytes harbor a glucosylceramide biosynthesis pathway involved in iNKT cell activation

scientific article published on 30 April 2019

Adipose tissue-resident immune cells: key players in immunometabolism.

scientific article published on 12 July 2012

Airway and interstitial lung disease are distinct entities in paediatric common variable immunodeficiency.

scientific article published on 2 June 2011

An update on the 'danger theory' in inhibitor development in hemophilia A

scientific article published on 25 April 2019

Antigen cross-presentation: extending recent laboratory findings to therapeutic intervention.

scientific article published on 11 May 2011

Antigen-specific IgA titres after 23-valent pneumococcal vaccine indicate transient antibody deficiency disease in children.

scientific article

Antitumor immune responses mediated by dendritic cells: How signals derived from dying cancer cells drive antigen cross-presentation

scientific article

Application of antigen cross-presentation research into patient care

scientific article

Autologous stem cell transplantation aids autoimmune patients by functional renewal and TCR diversification of regulatory T cells.

scientific article

Autologous stem cell transplantation in autoimmune arthritis restores immune homeostasis by renewal of the natural Treg compartment.

scientific article

B-cell defects in common variable immunodeficiency: BCR signaling, protein clustering and hardwired gene mutations.

scientific article published on January 2011

Behavioral responses of epidermal Langerhans cells in situ to local pathological stimuli.

scientific article published in April 2006

Brief report: enrichment of activated group 3 innate lymphoid cells in psoriatic arthritis synovial fluid

scientific article published on 01 October 2015

Bystander T-Cells Support Clonal T-Cell Activation by Controlling the Release of Dendritic Cell-Derived Immune-Stimulatory Extracellular Vesicles

scientific article published on 12 March 2019

CCR7 plays no appreciable role in trafficking of central memory CD4 T cells to lymph nodes.

scientific article published on 9 August 2013

CD1d-mediated presentation of endogenous lipid antigens by adipocytes requires microsomal triglyceride transfer protein

scientific article published on 25 June 2014

CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance

scientific article (publication date: 14 January 2005)

CXCL4 Exposure Potentiates TLR-Driven Polarization of Human Monocyte-Derived Dendritic Cells and Increases Stimulation of T Cells.

scientific article published on 17 May 2017

CXCL4 is a driver of cytokine mRNA stability in monocyte-derived dendritic cells

scientific article published on 10 September 2019

Cancer immunotherapy: Moving beyond checkpoint inhibition

scientific article published on 27 November 2018

Central importance of immunoglobulin A in host defense against Giardia spp.

scientific article

Cognate CD4 T-cell licensing of dendritic cells heralds anti-cytomegalovirus CD8 T-cell immunity after human allogeneic umbilical cord blood transplantation

scientific article

Critical Role for CD1d-Restricted Invariant NKT Cells in Stimulating Intrahepatic CD8 T-Cell Responses to Liver Antigen

article

Critical role for programmed death 1 signaling and protein kinase B in augmented regulatory T-cell induction in cord blood.

scientific article

Defective TH17 development in human neonatal T cells involves reduced RORC2 mRNA content.

scientific article published on 29 May 2013

Defective control of vitamin D receptor-mediated epithelial STAT1 signalling predisposes to severe respiratory syncytial virus bronchiolitis.

scientific article published on January 2014

Defects in mitochondrial clearance predispose human monocytes to interleukin-1β hypersecretion.

scientific article published on 19 December 2013

Deletion of calcineurin and myocyte enhancer factor 2 (MEF2) binding domain of Cabin1 results in enhanced cytokine gene expression in T cells

scientific article

Development of a unique anti-AML immune therapy consisting of cord blood HSCT and cord blood stem cell-derived dendritic cell (CB-DC) vaccination.

scientific article published on 7 November 2013

Development of intravital intermittent confocal imaging system for studying Langerhans cell turnover.

scientific article published on 22 June 2006

Dysfunctional BLK in common variable immunodeficiency perturbs B-cell proliferation and ability to elicit antigen-specific CD4+ T-cell help.

scientific article published on May 2015

Elevated Th17 response in infants undergoing respiratory viral infection.

scientific article published on 17 March 2014

Endocytosed soluble cowpox virus protein CPXV012 inhibits antigen cross-presentation in human monocyte-derived dendritic cells.

scientific article published on 19 October 2017

Endogenous lipid antigens for invariant Natural Killer T cells hold the reins in adipose tissue homeostasis

scientific article published on 12 September 2017

Endosomal processing for antigen presentation mediated by CD1 and Class I major histocompatibility complex: roads to display or destruction.

scientific article published on June 2009

Erythematous nodes, urticarial rash and arthralgias in a large pedigree withNLRC4-related autoinflammatory disease, expansion of the phenotype

scientific article published on 08 December 2016

F-actin remodeling defects as revealed in primary immunodeficiency disorders

scientific article

Fcγ receptor antigen targeting potentiates cross-presentation by human blood and lymphoid tissue BDCA-3+ dendritic cells

scientific article published on 23 October 2012

Functional Inactivation of Immature Dendritic Cells by the Intracellular Parasite Toxoplasma gondii

scientific article published on 01 August 2004

Generation of a cord blood-derived Wilms Tumor 1 dendritic cell vaccine for AML patients treated with allogeneic cord blood transplantation.

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

IL-21R is essential for epicutaneous sensitization and allergic skin inflammation in humans and mice.

scientific article published on 15 December 2008

Immunometabolic Activation of Invariant Natural Killer T Cells.

scientific article published on 28 May 2018

In vivo control of endosomal architecture by class II-associated invariant chain and cathepsin S

scientific article published on 01 September 2005

Increased intra-articular granzyme M may trigger local IFN-λ1/IL-29 response in rheumatoid arthritis

scientific article published on 06 June 2019

Increased prevalence of gastrointestinal viruses and diminished secretory immunoglobulin a levels in antibody deficiencies

scientific article

Increased risk of hematologic malignancies in primary immunodeficiency disorders: opportunities for immunotherapy.

scientific article published on 27 February 2018

Invariant natural killer T cells in adipose tissue: novel regulators of immune-mediated metabolic disease.

scientific article published on 09 July 2013

Local IL-17A potentiates early neutrophil recruitment to the respiratory tract during severe RSV infection

scientific article

Lymph node stromal cells constrain immunity via MHC class II self-antigen presentation.

scientific article published on 19 November 2014

MICAL-L1-related and unrelated mechanisms underlying elongated tubular endosomal network (ETEN) in human dendritic cells

scientific article published on 23 December 2014

Maintenance of peripheral tolerance through controlled tissue homing of antigen-specific T cells in K14-mOVA mice.

scientific article

Measurement of pneumococcal polysaccharide vaccine responses for immunodeficiency diagnostics: combined IgG responses compared to serotype specific IgG responses.

scientific article published on 24 July 2013

Membrane specializations and endosome maturation in dendritic cells and B cells.

scientific article published on April 2004

Mevalonate kinase deficiency, a metabolic autoinflammatory disease.

scientific article published on 04 October 2012

Mitochondria in autoinflammation: cause, mediator or bystander?

scientific article published on 04 April 2015

Monovalent ligation of the B cell receptor induces receptor activation but fails to promote antigen presentation.

scholarly article

Myeloid differentiation factor 88 is required for cross-priming in vivo.

scientific article published in March 2004

NFκB and MHC-1 Interplay in Neuroblastoma and Immunotherapy

scientific article published on 09 October 2018

Natural killer T cells in adipose tissue prevent insulin resistance

scientific article

Natural killer cells facilitate PRAME-specific T-cell reactivity against neuroblastoma

scientific article

Nedd4-Binding Protein 1 and TNFAIP3-Interacting Protein 1 Control MHC-1 Display in Neuroblastoma

scientific article published on 13 September 2018

Nonspreading Rift Valley Fever Virus Infection of Human Dendritic Cells Results in Downregulation of CD83 and Full Maturation of Bystander Cells.

scientific article published on 17 November 2015

PReS-FINAL-1006: Autologous bone marrow transplantation in autoimmune, experimental arthritis restores immune homeostasis by renewal of the natural tregs compartment.

scientific article

PSTPIP1 controls immune synapse stability in human T-cells

scientific article published on 9 February 2018

Perception of self: distinguishing autoimmunity from autoinflammation

scientific article published on 12 May 2015

Pneumococcal capsular polysaccharide vaccine-mediated protection against serotype 3 Streptococcus pneumoniae in immunodeficient mice

scientific article published on 12 January 2007

Preliminary Evaluation of a Bunyavirus Vector for Cancer Immunotherapy

scientific article published on 17 June 2015

Protein kinase C delta stimulates antigen presentation by Class II MHC in murine dendritic cells.

scientific article published on 19 April 2007

Recruitment of Rab27a to phagosomes controls microbial antigen cross-presentation by dendritic cells.

scientific article published on 8 September 2008

Reduced serpinB9-mediated caspase-1 inhibition can contribute to autoinflammatory disease.

scientific article published on 15 March 2016

Requirement for invariant chain in macrophages for Mycobacterium tuberculosis replication and CD1d antigen presentation

scientific article published on 16 May 2011

Requirements for T cell-polarized tubulation of class II+ compartments in dendritic cells

scientific article published on 01 December 2003

Review of immune tolerance induction in hemophilia A.

scientific article published on 15 February 2018

SLAM is a microbial sensor that regulates bacterial phagosome functions in macrophages.

scientific article published on 5 September 2010

Splenic dendritic cell involvement in FXR-mediated amelioration of DSS colitis.

scientific article published on 7 November 2015

T cells induce extended class II MHC compartments in dendritic cells in a Toll-like receptor-dependent manner

scientific article published on 01 October 2003

T lymphocyte-dependent and -independent regulation of Cxcl8 expression in zebrafish intestines

scientific article published on 25 November 2013

T lymphocytes control microbial composition by regulating the abundance of Vibrio in the zebrafish gut

scientific article

TGF-β suppresses β-catenin-dependent tolerogenic activation program in dendritic cells.

scientific article

TLR3 triggering regulates PD-L1 (CD274) expression in human neuroblastoma cells.

scientific article published on 16 February 2015

Targeted next-generation sequencing: a novel diagnostic tool for primary immunodeficiencies.

scientific article published on 15 October 2013

The actin-based motor protein myosin II regulates MHC class II trafficking and BCR-driven antigen presentation.

scientific article

Translating cell biology in vitro to immunity in vivo.

scientific article published in July 2004

Tubulation of endosomal structures in human dendritic cells by Toll-like receptor ligation and lymphocyte contact accompanies antigen cross-presentation.

scientific article

Unprenylated RhoA contributes to IL-1β hypersecretion in mevalonate kinase deficiency model through stimulation of Rac1 activity.

scientific article