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List of works by Frederic Chedin

A SPOT on the chromatin landscape? Histone peptide arrays as a tool for epigenetic research

scientific article published on 04 June 2008

A five-nucleotide sequence protects DNA from exonucleolytic degradation by AddAB, the RecBCD analogue of Bacillus subtilis

scientific article published on 01 September 1998

A novel family of regulated helicases/nucleases from Gram-positive bacteria: insights into the initiation of DNA recombination.

scientific article

A systematic search for DNA methyltransferase polymorphisms reveals a rare DNMT3L variant associated with subtelomeric hypomethylation.

scientific article

Arginine methylation facilitates the recruitment of TOP3B to chromatin to prevent R loop accumulation.

scientific article

Attenuation of RNA polymerase II pausing mitigates BRCA1-associated R-loop accumulation and tumorigenesis.

scientific article

Best practices for the visualization, mapping, and manipulation of R-loops

scientific article published on 07 January 2021

Co-transcriptional R-loops are the main cause of estrogen-induced DNA damage

scientific article published on 23 August 2016

Comprehensive Proteomic Analysis of Mesenchymal Stem Cell Exosomes Reveals Modulation of Angiogenesis via Nuclear Factor-KappaB Signaling

scientific article

DNA Topoisomerase I differentially modulates R-loops across the human genome

scientific article published on 30 July 2018

DNMT3L modulates significant and distinct flanking sequence preference for DNA methylation by DNMT3A and DNMT3B in vivo.

scientific article

Dimethyl fumarate dosing in humans increases frataxin expression: A potential therapy for Friedreich's Ataxia

scientific article published on 03 June 2019

Emerging roles for R-loop structures in the management of topological stress

scientific article published on 27 February 2020

GC skew at the 5' and 3' ends of human genes links R-loop formation to epigenetic regulation and transcription termination

scientific article

GC skew is a conserved property of unmethylated CpG island promoters across vertebrates

scientific article published on 7 August 2015

Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi-Goutières syndrome

scientific article published on 16 July 2015

High-resolution, strand-specific R-loop mapping via S9.6-based DNA-RNA immunoprecipitation and high-throughput sequencing

scientific article published on 03 May 2019

Hybrids in the chromatin

scientific article published on 28 August 2017

ICF Syndrome Mutations Cause a Broad Spectrum of Biochemical Defects in DNMT3B-Mediated De Novo DNA Methylation ⬇️

scientific article published on April 27, 2011

Inactive DNMT3B splice variants modulate de novo DNA methylation

scientific article (publication date: 2013)

Inhibition of a naturally occurring rolling-circle replicon in derivatives of the theta-replicating plasmid pIP501

scientific article published on 01 August 1998

Interplay between DNA sequence and negative superhelicity drives R-loop structures

scientific article published on 08 March 2019

Nascent Connections: R-Loops and Chromatin Patterning

scientific article published on 25 October 2016

Novel homologs of replication protein A in archaea: implications for the evolution of ssDNA-binding proteins.

scientific article

PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma

scientific article published on 30 July 2021

Physical and functional interactions between the human DNMT3L protein and members of the de novo methyltransferase family.

scientific article published in August 2005

Prevalent, Dynamic, and Conserved R-Loop Structures Associate with Specific Epigenomic Signatures in Mammals

scientific article published on 29 June 2016

R-Loop Formation Is a Distinctive Characteristic of Unmethylated Human CpG Island Promoters ⬇️

scientific article published on March 30, 2012

R-loop formation at Snord116 mediates topotecan inhibition of Ube3a-antisense and allele-specific chromatin decondensation.

scientific article published on 05 August 2013

RNA-DNA strand exchange by the Drosophila Polycomb complex PRC2

scientific article published on 14 April 2020

Reconstitution and mechanism of the stimulation of de novo methylation by human DNMT3L

scientific article

Telomeres in ICF syndrome cells are vulnerable to DNA damage due to elevated DNA:RNA hybrids

scientific article published on 24 January 2017

The Affinity of the S9.6 Antibody for Double-Stranded RNAs Impacts the Accurate Mapping of R-Loops in Fission Yeast

scientific article published on 28 December 2017

The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a

scientific article

The DNMT3 Family of Mammalian De Novo DNA Methyltransferases

scientific article published on January 1, 2011

The Recombination Hot Spot Chi Is Embedded within Islands of Preferred DNA Pairing Sequences in the E. coli Genome ⬇️

scientific article published on July 25, 1997

The extruded non-template strand determines the architecture of R-loops

scientific article published on 01 July 2019

Topoisomerase 1 prevents replication stress at R-loop-enriched transcription termination sites

scientific article published on 07 August 2020

Transcription-associated R-loop formation across the human FMR1 CGG-repeat region

scientific article (publication date: April 2014)

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