List of works - Marcus Altfeld

1269. Cohort Profile: The Translational Platform HIV (TP-HIV), a Multicenter Cohort Project in Germany

scientific article published on 23 October 2019

A deeper view of transmitted/founder viruses using 454 whole genome deep sequencing

scientific article published on 13 September 2012

A simple, sensitive, and low-cost FACS assay for detecting antibodies against the native SARS-CoV-2 spike protein

scientific article published on 12 May 2021

A subset of HLA-DP molecules serve as ligands for the natural cytotoxicity receptor NKp44

scientific article published on 29 July 2019

AIDS restriction HLA allotypes target distinct intervals of HIV-1 pathogenesis

scientific article published on 20 November 2005

Acute HIV-1 infection is associated with increased plasma levels of heme oxygenase-1 (HO-1) and presence of HO-1-specific regulatory T cells

scientific article published on 04 January 2017

Acute HIV‐1 Infection: What’s New? Where Are We Going?

article

Androgens predispose males to monocyte-mediated immunopathology by inducing the expression of leukocyte recruitment factor CXCL1

scientific article published on 10 July 2020

Assessment of the antiviral capacity of primary natural killer cells by optimized in vitro quantification of HIV-1 replication

scientific article published on 16 April 2016

Association between HIV Type 1-specific T cell responses and CD4+ T cell counts or CD4+:CD8+ T cell ratios in HIV Type 1 subtype B infection in China

scientific article published on August 2006

Author Correction: Sex-specific innate immune selection of HIV-1 in utero is associated with increased female susceptibility to infection

scientific article published on 04 May 2020

CCL21-expression and accumulation of CCR7 NK cells in livers of patients with primary sclerosing cholangitis

scientific article published on 27 February 2019

CD107a as a functional marker for the identification of natural killer cell activity.

scientific article published in November 2004

CD49a Expression Identifies a Subset of Intrahepatic Macrophages in Humans.

scientific article published on 7 June 2019

Changes in HIV-1 Capsid Stability Induced by Common Cytotoxic-T-Lymphocyte-Driven Viral Sequence Mutations.

scientific article

Clonotype tracking of TCR repertoires during chronic virus infections.

scientific article published on December 2002

Comprehensive Characterization of Cellular Immune Responses Following Ebola Virus Infection.

scientific article published on 31 October 2016

Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load.

scientific article

Correction: Characteristics of the Earliest Cross-Neutralizing Antibody Response to HIV-1.

scientific article published in March 2011

Crippling HIV one mutation at a time

Cytotoxic T-lymphocyte (CTL) responses directed against regulatory and accessory proteins in HIV-1 infection

scientific article published on 01 September 2002

Distinct genital tract HIV-specific antibody profiles associated with tenofovir gel.

scientific article published on 27 January 2016

Dysregulated Tim-3 expression on natural killer cells is associated with increased Galectin-9 levels in HIV-1 infection.

scientific article published on 18 July 2013

Early type I Interferon response induces upregulation of human β-defensin 1 during acute HIV-1 infection.

scientific article

Early viral replication in lymph nodes provides HIV with a means by which to escape NK-cell-mediated control

scientific article published on 12 August 2011

Elevated Levels of Microbial Translocation Markers and CCL2 Among Older HIV-1-Infected Men

scientific article published on 22 October 2015

Erratum: Distinct genital tract HIV-specific antibody profiles associated with tenofovir gel

article

Failure of double protease inhibitor therapy as a salvage therapy for HIV-infected patients resistant to conventional triple therapy.

scientific article published in July 1999

Frequent and strong antibody-mediated NK cell activation to HIV-1 Env in individuals with chronic HIV-1 infection.

scientific article published on 13 September 2012

HIV-1 Vpu represents a minor target for cytotoxic T lymphocytes in HIV-1-infection

scientific article published on 01 May 2002

HIV-1 p24 derived epitopes modulate KIR2DL2-binding to HLA-Cw03.

scientific article published on 13 September 2012

HIV-1 specific CD8+ T cells with an effector phenotype and control of viral replication

scientific article published in The Lancet

HLA-C levels impact natural killer cell subset distribution and function.

scientific article published on 10 August 2016

HLA-Cw*0102-restricted HIV-1 p24 epitope variants can modulate the binding of the inhibitory KIR2DL2 receptor and primary NK cell function

article

Higher expression of several interferon-stimulated genes in HIV-1-infected females after adjusting for the level of viral replication.

scientific article published on 10 June 2013

Hobit expression by a subset of human liver-resident CD56bright Natural Killer cells

scientific article

Human Leukocyte Antigen F Presents Peptides and Regulates Immunity through Interactions with NK Cell Receptors.

scientific article published on June 2017

Human leukocyte antigen class I and class II allele frequencies and HIV-1 infection associations in a Chinese cohort.

scientific article published in February 2007

Human liver-derived CXCR6 NK cells are predominantly educated through NKG2A and show reduced cytokine production

scientific article published on 19 February 2019

Identification of HLA-A11-restricted HIV-1-specific cytotoxic T-lymphocyte epitopes in China

scientific article published on January 2007

Immune-driven recombination and loss of control after HIV superinfection.

scientific article published on 14 July 2008

Immunological strategies to target HIV persistence.

scientific article published on 6 April 2016

Implications of post-translational modifications of IRF7 on pDC IFN-alpha response.

scientific article published on 13 September 2012

Increased Natural Killer Cell Activity in Viremic HIV-1 Infection

article

Increased frequency and function of KIR2DL1-3⁺ NK cells in primary HIV-1 infection are determined by HLA-C group haplotypes.

scientific article

Induction of strong HIV-1-specific CD4+ T-cell responses using an HIV-1 gp120/NefTat vaccine adjuvanted with AS02A in antiretroviral-treated HIV-1-infected individuals.

scientific article published on January 2012

Innate immune reconstitution with suppression of HIV-1.

scientific article published on March 2016

Innate immune responses to toll-like receptor stimulation are altered during the course of pregnancy

article

Inter-clade cross-reactivity of HIV-1-specific T cell responses in human immunodeficiency virus type 1 infection in China

scientific article published on March 2007

Interactions Between KIR3DS1 and HLA-F Activate Natural Killer Cells to Control HCV Replication in Cell Culture

article

Interferon-γ-dependent immune responses contribute to the pathogenesis of sclerosing cholangitis in mice

scientific article published on 05 June 2019

KIR-HLA footprints and NK cell-mediated recognition of HIV-1.

scientific article published on 13 September 2012

Killer-cell Immunoglobulin-like Receptor (KIR) gene profiles modify HIV disease course, not HIV acquisition in South African women.

scientific article published on 25 January 2016

Kinetics of HIV-1 Latency Reversal Quantified on the Single-Cell Level Using a Novel Flow-Based Technique

scientific article published on 27 July 2016

Limited value of PCR for detection of Toxoplasma gondii in blood from human immunodeficiency virus-infected patients ⬇️

scientific article published on October 1, 1997

Loss of HIV-1-specific T cell proliferation in chronic HIV-1 infection: cause or consequence of viral replication?

scientific article published on 01 July 2005

Measuring HIV-1-specific T cell immunity: how valid are current assays?

scientific article published on 01 February 2008

NK cells in HIV-1 infection: evidence for their role in the control of HIV-1 infection.

scientific article

Natural Killer Cell Education Is Associated With a Distinct Glycolytic Profile

scientific article published on 19 December 2018

OA011-05. TLR-mediated pDC responses to HIV-1 ligands

article

OA031-04. Impairment of HIV-1-specific CD8+ T cell function by soluble epithelial adhesion molecules.

scientific article published on 22 October 2009

Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1

scientific article

P04-15. Prevalence of broadly neutralizing antibody responses during acute/early HIV infection

article

P09-10. Impact of CTL escape mutations in HIV-1 Nef on viral replication.

scientific article published on 22 October 2009

P10-01. MHC class I chain-related protein A shedding in chronic HIV-1 infection is associated with profound NK cell dysfunction

article

P10-11. NK cells do not accumulate at sites of HIV-replication but show increased activation

article

P16-12. Relative dominance of Gag-specific cytotoxic T lymphocytes is associated with viral load inversely in HIV-1 clade B' infected Chinese.

scientific article published on 22 October 2009

P16-18. Regulatory T cell frequencies correlate with T cell activation in chronic HIV-1 infection

article

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

scientific article (publication date: 21 September 2006)

Peptide-specific engagement of the activating NK cell receptor KIR2DS1.

scientific article published on 25 May 2017

Perspective natural killer cells: bridging innate and adaptive immunity?

scientific article published on 01 May 2006

Primary HIV-1 Strains Use Nef To Downmodulate HLA-E Surface Expression

scientific article published on 30 September 2019

Proliferative capacity exhibited by human liver-resident CD49a+CD25+ NK cells

scientific article published on 9 August 2017

Protective HLA alleles are associated with reduced LPS levels in acute HIV infection with implications for immune activation and pathogenesis

scientific article published on 26 August 2019

Rapid evolution of HIV-1 to functional CD8+ T-cell rResponses in humanized BLT mice.

scientific article published on 13 September 2012

Reactivation of hepatitis B in a long-term anti-HBs-positive patient with AIDS following lamivudine withdrawal

scientific article published on 01 August 1998

Reduced frequencies of NKp30+NKp46+, CD161+, and NKG2D+ NK cells in acute HCV infection may predict viral clearance.

scientific article published on 17 December 2010

Regulatory and accessory HIV-1 proteins: potential targets for HIV-1 vaccines?

scientific article

Role of KIR3DS1 in human diseases ⬇️

scientific article published on January 1, 2012

Sequence variations in HCV core-derived epitopes alter binding of KIR2DL3 to HLA-C∗03:04 and modulate NK cell function.

scientific article published on 4 April 2016

Sequential deregulation of NK cell subset distribution and function starting in acute HIV-1 infection.

scientific article published on 7 July 2005

Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-α Production in Women

scientific article

Sex differences in immunity

scientific article published on 11 February 2019

Sex, race, and geographic region influence clinical outcomes following primary HIV-1 infection

scientific article

Sex-Based Differences in HIV-1 Reservoir Activity and Residual Immune Activation

article

Sex-based differences in HIV type 1 pathogenesis

scientific article

Sex-specific innate immune selection of HIV-1 in utero is associated with increased female susceptibility to infection

scientific article published on 14 April 2020

Sexual dimorphism in HIV-1 infection

article

Strong and persistent CD4+ T-cell response in healthy adults immunized with a candidate HIV-1 vaccine containing gp120, Nef and Tat antigens formulated in three Adjuvant Systems.

scientific article

Structured treatment interruptions following immediate initiation of HAART in eight patients with acute HIV-1 seroconversion.

scientific article published in July 2006

TLR-mediated immune activation in HIV

scientific article published on 01 January 2009

TLR7-mediated activation of XBP1 correlates with the IFNα production in humans.

scientific article published on 10 April 2017

TLR7/9 antagonist reduces HIV-1-induced immune activation.

scientific article published on 13 September 2012

The quest for an HIV-1 therapeutic vaccine

scientific article published on 15 July 2005

The viral set point in primary HIV infection is associated with specific amino acids in position 97 of MHC class I

article

Tim-3-mediated signaling in NK cells may be modulated by increased Galectin-9 expression in HIV-1 infection.

scientific article published on 13 September 2012

Tissue-resident Eomes NK cells are the major innate lymphoid cell population in human infant intestine

scientific article published on 28 February 2019

Tissue-resident NK cells differ in their expression profile of the nutrient transporters Glut1, CD98 and CD71

scientific article published on 20 July 2018

Tumor necrosis factor α is associated with viral control and early disease progression in patients with HIV type 1 infection

scientific article

[Specific immune responses to human immunodeficiency virus type 1 Gag, Tat, Rev and Nef proteins]

scientific article published on 01 March 2005

List of works by Marcus Altfeld

1269. Cohort Profile: The Translational Platform HIV (TP-HIV), a Multicenter Cohort Project in Germany

A deeper view of transmitted/founder viruses using 454 whole genome deep sequencing

A simple, sensitive, and low-cost FACS assay for detecting antibodies against the native SARS-CoV-2 spike protein

A subset of HLA-DP molecules serve as ligands for the natural cytotoxicity receptor NKp44

AIDS restriction HLA allotypes target distinct intervals of HIV-1 pathogenesis

Acute HIV-1 infection is associated with increased plasma levels of heme oxygenase-1 (HO-1) and presence of HO-1-specific regulatory T cells

Acute HIV‐1 Infection: What’s New? Where Are We Going?

Androgens predispose males to monocyte-mediated immunopathology by inducing the expression of leukocyte recruitment factor CXCL1

Assessment of the antiviral capacity of primary natural killer cells by optimized in vitro quantification of HIV-1 replication

Association between HIV Type 1-specific T cell responses and CD4+ T cell counts or CD4+:CD8+ T cell ratios in HIV Type 1 subtype B infection in China

Author Correction: Sex-specific innate immune selection of HIV-1 in utero is associated with increased female susceptibility to infection

CCL21-expression and accumulation of CCR7 NK cells in livers of patients with primary sclerosing cholangitis

CD107a as a functional marker for the identification of natural killer cell activity.

CD49a Expression Identifies a Subset of Intrahepatic Macrophages in Humans.

Changes in HIV-1 Capsid Stability Induced by Common Cytotoxic-T-Lymphocyte-Driven Viral Sequence Mutations.

Clonotype tracking of TCR repertoires during chronic virus infections.

Comprehensive Characterization of Cellular Immune Responses Following Ebola Virus Infection.

Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load.

Correction: Characteristics of the Earliest Cross-Neutralizing Antibody Response to HIV-1.

Crippling HIV one mutation at a time

Cytotoxic T-lymphocyte (CTL) responses directed against regulatory and accessory proteins in HIV-1 infection

Distinct genital tract HIV-specific antibody profiles associated with tenofovir gel.

Dysregulated Tim-3 expression on natural killer cells is associated with increased Galectin-9 levels in HIV-1 infection.

Early type I Interferon response induces upregulation of human β-defensin 1 during acute HIV-1 infection.

Early viral replication in lymph nodes provides HIV with a means by which to escape NK-cell-mediated control

Elevated Levels of Microbial Translocation Markers and CCL2 Among Older HIV-1-Infected Men

Erratum: Distinct genital tract HIV-specific antibody profiles associated with tenofovir gel

Failure of double protease inhibitor therapy as a salvage therapy for HIV-infected patients resistant to conventional triple therapy.

Frequent and strong antibody-mediated NK cell activation to HIV-1 Env in individuals with chronic HIV-1 infection.

HIV-1 Vpu represents a minor target for cytotoxic T lymphocytes in HIV-1-infection

HIV-1 p24 derived epitopes modulate KIR2DL2-binding to HLA-Cw03.

HIV-1 specific CD8+ T cells with an effector phenotype and control of viral replication

HLA-C levels impact natural killer cell subset distribution and function.

HLA-Cw*0102-restricted HIV-1 p24 epitope variants can modulate the binding of the inhibitory KIR2DL2 receptor and primary NK cell function

Higher expression of several interferon-stimulated genes in HIV-1-infected females after adjusting for the level of viral replication.

Hobit expression by a subset of human liver-resident CD56bright Natural Killer cells

Human Leukocyte Antigen F Presents Peptides and Regulates Immunity through Interactions with NK Cell Receptors.

Human leukocyte antigen class I and class II allele frequencies and HIV-1 infection associations in a Chinese cohort.

Human liver-derived CXCR6 NK cells are predominantly educated through NKG2A and show reduced cytokine production

Identification of HLA-A11-restricted HIV-1-specific cytotoxic T-lymphocyte epitopes in China

Immune-driven recombination and loss of control after HIV superinfection.

Immunological strategies to target HIV persistence.

Implications of post-translational modifications of IRF7 on pDC IFN-alpha response.

Increased Natural Killer Cell Activity in Viremic HIV-1 Infection

Increased frequency and function of KIR2DL1-3⁺ NK cells in primary HIV-1 infection are determined by HLA-C group haplotypes.

Induction of strong HIV-1-specific CD4+ T-cell responses using an HIV-1 gp120/NefTat vaccine adjuvanted with AS02A in antiretroviral-treated HIV-1-infected individuals.

Innate immune reconstitution with suppression of HIV-1.

Innate immune responses to toll-like receptor stimulation are altered during the course of pregnancy

Inter-clade cross-reactivity of HIV-1-specific T cell responses in human immunodeficiency virus type 1 infection in China

Interactions Between KIR3DS1 and HLA-F Activate Natural Killer Cells to Control HCV Replication in Cell Culture

Interferon-γ-dependent immune responses contribute to the pathogenesis of sclerosing cholangitis in mice

KIR-HLA footprints and NK cell-mediated recognition of HIV-1.

Killer-cell Immunoglobulin-like Receptor (KIR) gene profiles modify HIV disease course, not HIV acquisition in South African women.

Kinetics of HIV-1 Latency Reversal Quantified on the Single-Cell Level Using a Novel Flow-Based Technique

Limited value of PCR for detection of Toxoplasma gondii in blood from human immunodeficiency virus-infected patients ⬇️

Loss of HIV-1-specific T cell proliferation in chronic HIV-1 infection: cause or consequence of viral replication?

Measuring HIV-1-specific T cell immunity: how valid are current assays?

NK cells in HIV-1 infection: evidence for their role in the control of HIV-1 infection.

Natural Killer Cell Education Is Associated With a Distinct Glycolytic Profile

OA011-05. TLR-mediated pDC responses to HIV-1 ligands

OA031-04. Impairment of HIV-1-specific CD8+ T cell function by soluble epithelial adhesion molecules.

Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1

P04-15. Prevalence of broadly neutralizing antibody responses during acute/early HIV infection

P09-10. Impact of CTL escape mutations in HIV-1 Nef on viral replication.

P10-01. MHC class I chain-related protein A shedding in chronic HIV-1 infection is associated with profound NK cell dysfunction

P10-11. NK cells do not accumulate at sites of HIV-replication but show increased activation

P16-12. Relative dominance of Gag-specific cytotoxic T lymphocytes is associated with viral load inversely in HIV-1 clade B' infected Chinese.

P16-18. Regulatory T cell frequencies correlate with T cell activation in chronic HIV-1 infection

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

Peptide-specific engagement of the activating NK cell receptor KIR2DS1.

Perspective natural killer cells: bridging innate and adaptive immunity?

Primary HIV-1 Strains Use Nef To Downmodulate HLA-E Surface Expression

Proliferative capacity exhibited by human liver-resident CD49a+CD25+ NK cells

Protective HLA alleles are associated with reduced LPS levels in acute HIV infection with implications for immune activation and pathogenesis

Rapid evolution of HIV-1 to functional CD8+ T-cell rResponses in humanized BLT mice.

Reactivation of hepatitis B in a long-term anti-HBs-positive patient with AIDS following lamivudine withdrawal

Reduced frequencies of NKp30+NKp46+, CD161+, and NKG2D+ NK cells in acute HCV infection may predict viral clearance.

Regulatory and accessory HIV-1 proteins: potential targets for HIV-1 vaccines?

Role of KIR3DS1 in human diseases ⬇️