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List of works by Erwin Neher

A comparison between exocytic control mechanisms in adrenal chromaffin cells and a glutamatergic synapse

scientific article published on 3 October 2006

A patch-clamp study of bovine chromaffin cells and of their sensitivity to acetylcholine.

scientific article

A small pool of vesicles maintains synaptic activity in vivo

scientific article

A special pair of phytohormones controls excitability, slow closure, and external stomach formation in the Venus flytrap

scientific article published on 06 September 2011

A two-step model of secretion control in neuroendocrine cells

scientific article published on 01 July 1993

Abstracts from the 2nd International Genomic Medicine Conference (IGMC 2013), November 24-27, 2013, Jeddah, Kingdom of Saudi Arabia

Actin- and Myosin-Dependent Vesicle Loading of Presynaptic Docking Sites Prior to Exocytosis

scientific article published in August 2016

Alteration of Ca2+Dependence of Neurotransmitter Release by Disruption of Ca2+Channel/Syntaxin Interaction ⬇️

scientific article published on September 1, 1997

Analysis of FRET signals in the presence of free donors and acceptors

scientific article published on 5 October 2007

Application of an Epac activator enhances neurotransmitter release at excitatory central synapses.

scientific article

Applying spectral fingerprinting to the analysis of FRET images

scientific article published on 01 June 2004

Asymmetric membranes resulting from the fusion of two black lipid bilayers

scientific article published in December 1974

Blind Source Separation Techniques For The Decomposition Of Multiply Labeled Fluorescence Images

Blind source separation techniques for the decomposition of multiply labeled fluorescence images

scientific article published on May 2009

Blocking endocytosis enhances short-term synaptic depression under conditions of normal availability of vesicles

scientific article published in October 2013

Building Bridges through Science.

scientific article published in November 2017

Ca(2+)-activated K+ channels modulate muscarinic secretion in cat chromaffin cells ⬇️

scientific article published on August 1, 1992

Calcium Dependence of Exocytosis and Endocytosis at the Cochlear Inner Hair Cell Afferent Synapse

scientific article published on 01 March 2001

Calcium buffers in flash-light

scientific article published on December 2000

Calcium dependence of the rate of exocytosis in a synaptic terminal

scientific article

Calcium gradients and buffers in bovine chromaffin cells ⬇️

scientific article published on May 1, 1992

Calcium sensor kinase activates potassium uptake systems in gland cells of Venus flytraps

scientific article published on 21 May 2015

Calcium signals and synaptic short-term plasticity in the central nervous system

scientific article published on 01 January 2001

Calcium-buffering effects of gluconate and nucleotides, as determined by a novel fluorimetric titration method

scientific article published on 5 September 2014

Calmodulin mediates rapid recruitment of fast-releasing synaptic vesicles at a calyx-type synapse

scientific article published in December 2001

Chloride conductance activated by external agonists and internal messengers in rat peritoneal mast cells.

scientific article

Combining deconvolution and fluctuation analysis to determine quantal parameters and release rates

scientific article published on December 2003

Combining deconvolution and noise analysis for the estimation of transmitter release rates at the calyx of held.

scientific article

Comparison of Secretory Responses as Measured by Membrane Capacitance and by Amperometry ⬇️

scientific article published on April 1, 1998

Complexin stabilizes newly primed synaptic vesicles and prevents their premature fusion at the mouse calyx of held synapse.

scientific article

Complexin: Does It Deserve Its Name? ⬇️

scientific article published on 01 December 2010

Conductance fluctuations and ionic pores in membranes ⬇️

scientific article published on January 1, 1977

Controls on calcium influx

scientific article published in Nature

Correction for liquid junction potentials in patch clamp experiments

scientific article published on January 1, 1992

Counting Vesicular Release Events Reveals Binomial Release Statistics at Single Glutamatergic Synapses.

scientific article published in April 2016

Cytosolic Ca2+ acts by two separate pathways to modulate the supply of release-competent vesicles in chromaffin cells

scientific article published on June 1998

Delay in vesicle fusion revealed by electrochemical monitoring of single secretory events in adrenal chromaffin cells

scientific article published on March 5, 1992

Depression and augmentation of quantal release in adrenal chromaffin cells.

scientific article published on January 1994

Design of the EPC-9, a computer-controlled patch-clamp amplifier. 2. Software

scientific article published in February 1995

Details of Ca2+ dynamics matter

scientific article published on 01 April 2008

Dielectric relaxation studies of ionic processes in lysolecithin-packaged gramicidin channels ⬇️

scientific article published on January 1, 1982

Differences in Ca2+ buffering properties between excitatory and inhibitory hippocampal neurons from the rat

scientific article published on 01 June 2000

Differential Control of the Releasable Vesicle Pools by SNAP-25 Splice Variants and SNAP-23

scientific article published on 01 July 2003

Differential action of TEA+ on two K+-current components of a molluscan neurone ⬇️

scientific article published on 01 January 1972

Dihydropyridine-sensitive and omega-conotoxin-sensitive calcium channels in a mammalian neuroblastoma-glioma cell line ⬇️

scientific article published on March 1, 1992

Direct modulation of synaptic vesicle priming by GABA(B) receptor activation at a glutamatergic synapse

scientific article published in August 2003

Discrete changes of cell membrane capacitance observed under conditions of enhanced secretion in bovine adrenal chromaffin cells

scientific article

Distinct kinetic changes in neurotransmitter release after SNARE protein cleavage.

scientific article published in July 2005

Dynamic control of synaptic vesicle replenishment and short-term plasticity by Ca(2+)-calmodulin-Munc13-1 signaling

scientific article published on 13 June 2013

Dynamically Primed Synaptic Vesicle States: Key to Understand Synaptic Short-Term Plasticity

scientific article published on 01 December 2018

Dynamics of volume-averaged intracellular Ca2+ in a rat CNS nerve terminal during single and repetitive voltage-clamp depolarizations.

scientific article published on 13 December 2016

Early requirement for alpha-SNAP and NSF in the secretory cascade in chromaffin cells

scientific article published on June 1999

Effects of hydrostatic pressure on membrane processes. Sodium channels, calcium channels, and exocytosis

scientific article

Emerging roles of presynaptic proteins in Ca++-triggered exocytosis

scientific article

Estimating synaptic parameters from mean, variance, and covariance in trains of synaptic responses

scientific article published on October 2001

Estimating transmitter release rates from postsynaptic current fluctuations.

scientific article published in December 2001

Estimation of mean exocytic vesicle capacitance in mouse adrenal chromaffin cells

scientific article

Estimation of quantal parameters at the calyx of Held synapse

scientific article

Estimation of quantal size and number of functional active zones at the calyx of Held synapse by nonstationary EPSC variance analysis.

scientific article

Examining synaptotagmin 1 function in dense core vesicle exocytosis under direct control of Ca2+

scientific article

Exocytotic mechanism studied by truncated and zero layer mutants of the C-terminus of SNAP-25.

scientific article

Fast calcium transients in rat peritoneal mast cells are not sufficient to trigger exocytosis

scientific article published on January 1986

Fast scanning and efficient photodetection in a simple two-photon microscope

scientific article

Fast vesicle fusion in living cells requires at least three SNARE complexes

scientific article published on 16 September 2010

Flowers for synaptic endocytosis

scientific article published in September 2009

Fluctuation and relaxation analysis of monazomycin-induced conductance in black lipid membranes

scientific article published on June 30, 1976

Fractional calcium currents through recombinant GluR channels of the NMDA, AMPA and kainate receptor subtypes ⬇️

scientific article published on June 1, 1995

Fractional contribution of calcium to the cation current through glutamate receptor channels ⬇️

scientific article published on July 1, 1993

Functional expression of the calcium release channel from skeletal muscle ryanodine receptor cDNA.

scientific article published on December 1989

Help from fast synapses

scientific article published in October 1996

Heterodimerization of serotonin receptors 5-HT1A and 5-HT7 differentially regulates receptor signalling and trafficking

scientific article

Heterogeneous presynaptic release probabilities: functional relevance for short-term plasticity

scientific article published on March 2003

Highly nonlinear photodamage in two-photon fluorescence microscopy

scientific article

How frequent are correlated changes in families of protein sequences?

scientific article

IgG from patients with Lambert-Eaton syndrome blocks voltage-dependent calcium channels

scientific article

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches ⬇️

scientific article published on August 1, 1981

Information transmission by synapses with short-term synaptic plasticity.

scientific article published on 6 July 2007

Inhibition of SNARE Complex Assembly Differentially Affects Kinetic Components of Exocytosis

scientific article published on 01 December 1999

Insect haptoelectrical stimulation of Venus flytrap triggers exocytosis in gland cells

scientific article published on 17 April 2017

Interactions in cation permeation through the gramicidin channel. Cs, Rb, K, Na, Li, Tl, H, and effects of anion binding

scientific article

Intracellular calcium dependence of large dense-core vesicle exocytosis in the absence of synaptotagmin I

scientific article

Intracellular calcium dependence of transmitter release rates at a fast central synapse

scientific article published on 01 August 2000

Intracellular calcium release mediated by two muscarinic receptor subtypes.

scientific article published in November 1988

Intracellularly injected tetanus toxin inhibits exocytosis in bovine adrenal chromaffin cells

scientific article published in November 1986

Involvement of actin polymerization in vesicle recruitment at the calyx of Held synapse.

scientific article

Inward current channels activated by intracellular Ca in cultured cardiac cells ⬇️

scientific article published on December 24, 1981

Ion Influx as a Transduction Signal in Mast Cells ⬇️

scientific article published on January 1, 1991

Ion channels for communication between and within cells

scientific article

Ionic Channels for Signal Transmission and Propagation

scientific article published on January 1, 1983

Ionic selectivity, saturation and block in gramicidin A channels: I. Theory for the electrical properties of ion selective channels having two pairs of binding sites and multiple conductance states

scientific article

Ionic selectivity, saturation, and block in gramicidin A channels. II. Saturation behavior of single channel conductances and evidence for the existence of multiple binding sites in the channel

scientific article

K + -activity determinations in cat cortex

scientific article published on January 1, 1972

Kinetic studies of Ca2+ binding and Ca2+ clearance in the cytosol of adrenal chromaffin cells

scientific article published on July 1997

Kinetics of Ca2+ binding to parvalbumin in bovine chromaffin cells: implications for [Ca2+] transients of neuronal dendrites

scientific article published on 01 June 2000

Kinetics of both synchronous and asynchronous quantal release during trains of action potential-evoked EPSCs at the rat calyx of Held

scientific article published on 4 October 2007

Kinetics of the secretory response in bovine chromaffin cells following flash photolysis of caged Ca2+ ⬇️

scientific article published on December 1, 1994

Local anaesthetics transiently block currents through single acetylcholine-receptor channels ⬇️

scientific article published on April 1, 1978

Low mobility of the Ca2+ buffers in axons of cultured Aplysia neurons

scientific article published in March 1997

Measurement of calibration constants for quantitative calcium fluorimetry

scientific article published on 01 October 2013

Measurement of extracellular potassium activity in cat cortex

scientific article published in February 1973

Measurement of extracellular potassium enrichment during a voltage clamp pulse

scientific article published on 01 January 1972

Mechanisms Underlying Phasic and Sustained Secretion in Chromaffin Cells from Mouse Adrenal Slices

scientific article published on 01 July 1999

Mechanisms determining the time course of secretion in neuroendocrine cells

scientific article published on 01 February 1996

Mechano-stimulation triggers turgor changes associated with trap closure in the Darwin plant Dionaea muscipula.

scientific article published on 27 November 2013

Merits and Limitations of Vesicle Pool Models in View of Heterogeneous Populations of Synaptic Vesicles

scientific article

Mice sans synaptotagmin

scientific article published in Nature

Mobile and immobile calcium buffers in bovine adrenal chromaffin cells

scientific article published in September 1993

Modeling buffered Ca2+ diffusion near the membrane: implications for secretion in neuroendocrine cells

scientific article

Molecular biology meets microelectronics

scientific article published on 01 February 2001

Multiple Forms of Endocytosis In Bovine Adrenal Chromaffin Cells ⬇️

scientific article published on November 17, 1997

Multiple kinetic components of exocytosis distinguished by neurotoxin sensitivity

scientific article published on 01 July 1998

Multiple roles of calcium ions in the regulation of neurotransmitter release

scientific article published on September 2008

Munc13-1 acts as a priming factor for large dense-core vesicles in bovine chromaffin cells

scientific article

Munc13-1 is a presynaptic phorbol ester receptor that enhances neurotransmitter release

scientific article published on July 1998

Munc18-1 promotes large dense-core vesicle docking

scientific journal article

Neuronal Ca2+ signalling takes the local route

scientific article

Neurosecretion: what can we learn from chromaffin cells

scientific article published on 11 August 2017

Nobel lecture. Ion channels for communication between and within cells

scientific article

Noise analysis of drug induced voltage clamp currents in denervated frog muscle fibres ⬇️

scientific article published on July 1, 1976

Novel chloride conductance in the membrane of bovine chromaffin cells activated by intracellular GTP gamma S

scientific article published on 01 May 1991

Optimizing imaging parameters for the separation of multiple labels in a fluorescence image

scientific article published in January 2004

Patch Clamp Techniques for Studying Ionic Channels in Excitable Membranes ⬇️

scientific article published on January 1, 1984

Patch clamp techniques: an overview

scientific article published on January 1, 1992

Patch-clamp techniques for time-resolved capacitance measurements in single cells ⬇️

scientific article published on February 1, 1988

Plasmalemmal phosphatidylinositol-4,5-bisphosphate level regulates the releasable vesicle pool size in chromaffin cells.

scientific article

Potassium channels in cultured bovine adrenal chromaffin cells

scientific article published on October 1985

Preferential potentiation of fast-releasing synaptic vesicles by cAMP at the calyx of Held

scholarly article

Presynaptic Depression at a Calyx Synapse: The Small Contribution of Metabotropic Glutamate Receptors ⬇️

scientific article published on November 1, 1997

Presynaptic calcium and control of vesicle fusion

scientific article

Probing the intracellular calcium sensitivity of transmitter release during synaptic facilitation

scientific article published on 01 March 2003

Properties of a model of Ca++-dependent vesicle pool dynamics and short term synaptic depression

scientific article published on November 1999

Properties of somatic membrane patches of snail neurons under voltage clamp ⬇️

scientific article published on January 1, 1971

Protein kinase C enhances exocytosis from chromaffin cells by increasing the size of the readily releasable pool of secretory granules

scientific article published in June 1996

Protein kinase C-dependent phosphorylation of synaptosome-associated protein of 25 kDa at Ser187 potentiates vesicle recruitment

scientific article published on 01 November 2002

Protein scaffolds in the coupling of synaptic exocytosis and endocytosis

scientific article published on 09 February 2011

Quantitative analysis of calcium-dependent vesicle recruitment and its functional role at the calyx of Held synapse

scientific article published on 01 December 2007

Quantitative aspects of calcium fluorimetry

scientific article published in October 2013

Quantitative intensity-based FRET approaches--a comparative snapshot

scientific article

Quantitative relationship between transmitter release and calcium current at the calyx of held synapse.

scientific article

R-Type Ca2+ channels are coupled to the rapid component of secretion in mouse adrenal slice chromaffin cells.

scientific article published in November 2000

Rapid changes of potassium concentration at the outer surface of exposed single neurons during membrane current flow

scientific article published on March 1973

Rapid exocytosis in single chromaffin cells recorded from mouse adrenal slices

scientific article published on 01 April 1997

Rat brain serotonin receptors in Xenopus oocytes are coupled by intracellular calcium to endogenous channels

scientific article

Rates of diffusional exchange between small cells and a measuring patch pipette.

scientific article

Receptor-operated Ca channels

scientific article published in Nature

Reduced endogenous Ca2+ buffering speeds active zone Ca2+ signaling

scientific article published on 26 May 2015

Regulation of calcium influx by second messengers in rat mast cells.

scientific article published in August 1988

Regulation of releasable vesicle pool sizes by protein kinase A-dependent phosphorylation of SNAP-25.

scientific article published in February 2004

Regulation of the mannose 6-phosphate/IGF II receptor expression at the cell surface by mannose 6-phosphate, insulin like growth factors and epidermal growth factor

scientific article published on March 1989

Release kinetics, quantal parameters and their modulation during short-term depression at a developing synapse in the rat CNS.

scientific article published on 11 August 2005

Released fraction and total size of a pool of immediately available transmitter quanta at a calyx synapse

scientific article published in June 1999

Roles of Ion fluxes, metabolism and redox balance in cancer therapy

scientific article published on 29 October 2020

Second messenger-activated calcium influx in rat peritoneal mast cells.

scientific article

Secretion without full fusion

scientific article published in Nature

Secretory responses of rat peritoneal mast cells to high intracellular calcium

scientific article published on 01 January 1988

Selective effector coupling of muscarinic acetylcholine receptor subtypes.

scientific article published on December 1989

Separation of presynaptic and postsynaptic contributions to depression by covariance analysis of successive EPSCs at the calyx of Held synapse.

scientific article published in February 2002

Short-term plasticity turns plastic. Focus on "synaptic transmission at the calyx of Held under in vivo-like activity levels"

scientific article published on 20 June 2007

Signal/noise analysis of FRET-based sensors

scientific article published on October 2010

Single Na+ channel currents observed in cultured rat muscle cells ⬇️

scientific article published on October 2, 1980

Single channel activity associated with the calcium dependent outward current in Helix pomatia

scientific article published on 01 March 1981

Single channel recordings of K+ currents in squid axons

scientific article published in Nature

Small-conductance Ca(2+)-activated K+ channels in bovine chromaffin cells

scientific article published on 01 April 1993

Sodium and calcium channels in bovine chromaffin cells ⬇️

scientific article published on October 1, 1982

Some Subtle Lessons from the Calyx of Held Synapse

scientific article published on January 2017

Spatial and temporal aspects of Ca changes in secretion control

scientific article published on May 1993

Specificity emerges in the dissection of diacylglycerol- and protein kinase C-mediated signalling pathways

scholarly article

Stimulation- and palmitoylation-dependent changes in oligomeric conformation of serotonin 5-HT1A receptors

scientific article

Stimulus-secretion coupling in mast cells

scientific article published on 01 January 1989

Substance P reduces acetylcholine-induced currents in isolated bovine chromaffin cells

scientific article published on 01 February 1984

Superpriming of synaptic vesicles after their recruitment to the readily releasable pool

scientific article published on 26 August 2013

Superpriming of synaptic vesicles as a common basis for intersynapse variability and modulation of synaptic strength.

scientific article

Swelling-induced catecholamine secretion recorded from single chromaffin cells

scientific article published on 01 December 1995

Synaptic vesicles in mature calyx of Held synapses sense higher nanodomain calcium concentrations during action potential-evoked glutamate release

scientific article

Synaptotagmin has an essential function in synaptic vesicle positioning for synchronous release in addition to its role as a calcium sensor

article

The Ca signal from fura-2 loaded mast cells depends strongly on the method of dye-loading

scientific article published on 01 November 1985

The Dionaea muscipula ammonium channel DmAMT1 provides NH₄⁺ uptake associated with Venus flytrap's prey digestion

scientific article

The Patch Clamp Technique

scientific article

The SNARE protein SNAP-25 is linked to fast calcium triggering of exocytosis

scientific article

The Venus Flytrap Dionaea muscipula Counts Prey-Induced Action Potentials to Induce Sodium Uptake

scientific article

The action of ammonium on postsynaptic inhibition of cat spinal motoneurons

scientific article published in January 1970

The calcium dependence of vesicle exocytosis.

scientific article published on January 1987

The charge carried by single-channel currents of rat cultured muscle cells in the presence of local anaesthetics

scientific article published in June 1983

The coupling between synaptic vesicles and Ca2+ channels determines fast neurotransmitter release

scientific article

The desert plant Phoenix dactylifera closes stomata via nitrate-regulated SLAC1 anion channel

scientific article published on 3 July 2017

The equilibration time course of (K + ) 0 in cat cortex

scientific article published in April 1973

The extracellular patch clamp: A method for resolving currents through individual open channels in biological membranes ⬇️

scientific article published on July 18, 1978

The influence of phospholipid polar groups on gramicidin channels

scientific article (publication date: 4 January 1977)

The most important recent advances in synapse research from my point of view--and what remains to be done

scientific article published on 01 September 2006

The patch-clamp technique in the study of secretion

scientific article published on April 1989

The properties of ionic channels measured by noise analysis in thin lipid membranes

scientific article published in January 1974

The readily releasable pool of vesicles in chromaffin cells is replenished in a temperature-dependent manner and transiently overfills at 37 degrees C.

scientific article

The reserve pool of synaptic vesicles acts as a buffer for proteins involved in synaptic vesicle recycling ⬇️

scientific article published on September 8, 2011

The role of calcium in stimulus-secretion coupling in excitable and non-excitable cells

scientific article

The timing of phasic transmitter release is Ca2+-dependent and lacks a direct influence of presynaptic membrane potential

scientific article

The use of fura-2 for estimating Ca buffers and Ca fluxes

scientific article published in November 1995

The use of the patch clamp technique to study second messenger-mediated cellular events

scientific article

Time course of Ca2+ concentration triggering exocytosis in neuroendocrine cells

scientific article

Toward an optically controlled brain

scientific article

Transients in global Ca2+ concentration induced by electrical activity in a giant nerve terminal

scientific article published on 25 March 2013

Transmitter release modulation by intracellular Ca2+ buffers in facilitating and depressing nerve terminals of pyramidal cells in layer 2/3 of the rat neocortex indicates a target cell-specific difference in presynaptic calcium dynamics

scientific article

Trifluoperazine reduces inward ionic currents and secretion by separate mechanisms in bovine chromaffin cells

scientific article published on 01 August 1984

Two Fast Transient Current Components during Voltage Clamp on Snail Neurons ⬇️

scientific article published on July 1, 1971

Two dye two wavelength excitation calcium imaging: results from bovine adrenal chromaffin cells ⬇️

scientific article published on July 1, 1998

Two-Dimensional Determination of the Cellular Ca2+ Binding in Bovine Chromaffin Cells ⬇️

scientific article published on October 1, 1998

Two-component latency distributions indicate two-step vesicular release at simple glutamatergic synapses

scientific article published in Nature Communications

Ultrastructural Organization of Bovine Chromaffin Cell Cortex—Analysis by Cryofixation and Morphometry of Aspects Pertinent to Exocytosis ⬇️

scientific article published on December 29, 1997

Usefulness and limitations of linear approximations to the understanding of Ca++ signals

scientific article

Venus Flytrap HKT1-Type Channel Provides for Prey Sodium Uptake into Carnivorous Plant Without Conflicting with Electrical Excitability

scientific article published on 5 October 2015

Venus Flytrap: How an Excitable, Carnivorous Plant Works

scientific article published on 11 January 2018

Veratridine-induced oscillations of cytosolic calcium and membrane potential in bovine chromaffin cells

scientific article published on 01 January 1995

Vesicle Pools and Ca2+ Microdomains: New Tools for Understanding Their Roles in Neurotransmitter Release ⬇️

scientific article published on March 1, 1998

Vesicle pools and short-term synaptic depression: lessons from a large synapse

scientific article

Voltage clamp on helix pomatia neuronal membrane; Current measurement over a limited area of the soma surface ⬇️

scientific article published on 01 January 1969

Voltage-dependence of drug-induced conductance in frog neuromuscular junction ⬇️

scientific article published on June 1, 1975

Volume-sensitive chloride conductance in bovine chromaffin cell membrane ⬇️

scientific article published on 01 April 1992

Washout phenomena in dialyzed mast cells allow discrimination of different steps in stimulus-secretion coupling

scientific article published in April 1987

What is rate-limiting during sustained synaptic activity: vesicle supply or the availability of release sites ⬇️

scientific article published on September 16, 2010

[The importance of calcium for secretion in excitable and non-excitable cells]

scientific article published on 01 January 1989

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