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List of works by Pieter Reitsma

5000 years old and still going strong

scientific article published on 01 November 2014

A C1173T dimorphism in the VKORC1 gene determines coumarin sensitivity and bleeding risk

scientific article

A CCA/CCG neutral dimorphism in the codon for Pro 626 of the human protein S gene PS alpha (PROS1).

scientific article

A Comparative Study of the Protein C Pathway in Septic and Nonseptic Patients with Organ Failure

scientific article published on 02 August 2007

A Dutch family with moderately severe hemophilia B (factor IXHeerde) has a missense mutation identical to that of factor IX London 2

scientific article published on May 1989

A Dutch pedigree with mild hemophilia B with a missense mutation in the first EGF domain (factor IXOud en Nieuw Gastel).

scientific article published on July 1989

A PstI RFLP of the LACI gene

scientific article published on October 1990

A case of two commentaries

scientific article published in May 2014

A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis.

scientific article

A frequent thrombomodulin amino acid dimorphism is not associated with thrombophilia

scientific article published on 01 May 1991

A functional single nucleotide polymorphism in the thrombin-activatable fibrinolysis inhibitor (TAFI) gene associates with outcome of meningococcal disease

article

A genetic propensity to high factor VII is not associated with the risk of myocardial infarction in men

scientific article published on 01 August 1998

A novel candidate mutation (Arg611-->His) in type I 'platelet discordant' von Willebrand's disease with desmopressin-induced thrombocytopenia.

scientific article

A patient with von Willebrand's disease characterized by a compound heterozygosity for a substitution of Arg854 by Gln in the putative factor-VIII-binding domain of von Willebrand factor (vWF) on one allele and very low levels of mRNA from the secon

scientific article published on 01 March 1992

Activated protein C resistance as an additional risk factor for thrombosis in protein C-deficient families.

scientific article

Activated protein C resistance: a comparison between two clotting assays and their relationship to the presence of the factor V Leiden mutation

scientific article published on 01 June 1996

Activation of innate immunity in patients with venous thrombosis: the Leiden Thrombophilia Study

scientific article (publication date: April 2004)

Acute and severe coagulopathy in adult mice following silencing of hepatic antithrombin and protein C production

scientific article published on 2 April 2013

Additional value of procalcitonin for diagnosis of infection in patients with fever at the emergency department

scientific article published on February 2010

Alternative splicing is responsible for the presence of two tissue factor mRNA species in LPS stimulated human monocytes

scientific article published on 01 February 1992

Alternatively spliced tissue factor induces angiogenesis through integrin ligation.

scientific article published on 29 October 2009

Alternatively spliced tissue factor promotes breast cancer growth in a β1 integrin-dependent manner.

scientific article published on 25 June 2013

Alternatively spliced tissue factor synergizes with the estrogen receptor pathway in promoting breast cancer progression.

scientific article

Analysis of blood coagulation in mice: pre-analytical conditions and evaluation of a home-made assay for thrombin-antithrombin complexes

scientific article

Analysis of the storage and secretion of von Willebrand factor in blood outgrowth endothelial cells derived from patients with von Willebrand disease

article

Angiogenic characteristics of blood outgrowth endothelial cells from patients with von Willebrand disease

scientific article published on 21 September 2015

Another year

scientific article published on 01 December 2014

Anti-inflammatory and anticoagulant effects of pravastatin in patients with type 2 diabetes.

scientific article published in February 2004

Apparent different thrombotic tendency in patients with factor V Leiden and protein C deficiency due to selection of patients.

scientific article published in December 1996

Application of two neutral MspI DNA polymorphisms in the analysis of hereditary protein C deficiency

scientific article published on October 22, 1990

April editorial

scientific article published on 01 April 2013

Arterial wall thickness and the risk of recurrent ischemic events in carriers of the prothrombin G20210A mutation with clinical manifestations of atherosclerosis

scientific article published on 01 July 2002

As time goes by

scientific article published on 01 February 2016

Assessment of coagulation and fibrinolysis in families with unexplained thrombophilia.

scientific article published in March 2009

August editorial: impact factors

scientific article published on 01 August 2013

Authors' Reply

Boycott.

scientific article

Brave real world

scientific article published on 01 November 2016

Characterization of a large chromosomal deletion in the PROS1 gene of a patient with protein S deficiency type I using long PCR.

scientific article published in March 1996

Coagulation factor Xa drives tumor cells into apoptosis through BH3-only protein Bim up-regulation

scientific article published on 19 April 2007

Coincidence

scientific article published on 24 October 2017

Complete abolishment of coagulant activity in monomeric disulfide-deficient tissue factor

scientific article published on 01 September 2011

Construction and characterization of thrombin-resistant variants of recombinant human protein S.

scientific article

Copy Number Variation of PROS1 and Protein S Deficiency Are Rare in a Population-Based Case-Control Study On Venous Thrombosis (MEGA study). ⬇️

scholarly article

Determination of the allelic and haplotype frequencies of three polymorphisms in the promoter region of the human protein C gene

scientific article published on 01 April 1994

Differential expression of tissue factor mRNA and protein expression in murine sepsis. The role of the granulocyte revisited

scientific article published on 01 February 2006

Diversity

scientific article published on 30 March 2016

Dominant type 1 von Willebrand disease caused by mutated cysteine residues in the D3 domain of von Willebrand factor.

scientific article published on October 1996

Don't look back

scientific article published in August 2017

Double strand conformation polymorphism (DSCP) detects two point mutations at codon 280 (AAC-->ATC) and at codon 431 (TAC-->AAC) of the blood coagulation factor VIII gene

article

Editorial

Evaluation of the von Willebrand factor Y1584C polymorphism as a potential risk factor for bleeding in patients receiving anticoagulant treatment with vitamin K antagonists

scientific article published on 01 April 2005

Evolutionary conservation of the tissue factor disulfide bonds and identification of a possible oxidoreductase binding motif

scientific article published on 01 January 2012

Experimental melanoma metastasis in lungs of mice with congenital coagulation disorders

scientific article published on 20 March 2008

Explanations for coagulation activation after air travel

scientific article published on 19 February 2010

Expression and characterization of recombinant human protein S in heterologous cells--studies of the interaction of amino acid residues leu-608 to glu-612 with human C4b-binding protein

scientific article published on 01 May 1992

Expression of tissue factor and tissue factor pathway inhibitor in monocytes in response to bacterial lipopolysaccharide and phorbolester

scientific article published on April 1994

F9 Malmö, factor IX and deep vein thrombosis

scientific article published on 13 March 2009

Factor V Leiden (FV R506Q) in families with inherited antithrombin deficiency

scientific article published on 01 March 1996

Factor V Leiden (resistance to activated protein C) increases the risk of myocardial infarction in young women

scientific article published on 01 April 1997

Factor V Leiden and fatal pulmonary embolism

scientific article published on 01 March 1998

Factor V Leiden, prothrombin G20210A, and risk of sudden coronary death in apparently healthy persons

scientific article published on 01 July 2002

Factor V Leiden: an additional risk factor for thrombosis in protein S deficient families?

scientific article published on 01 August 1995

Factor V levels and risk of venous thrombosis: The MEGA case-control study

scientific article published on 14 April 2018

Factor VII and fibrinogen levels as risk factors for venous thrombosis. A case-control study of plasma levels and DNA polymorphisms--the Leiden Thrombophilia Study (LETS)

scientific article published on 01 June 1994

Factor XI gene analysis in thrombophilia and factor XI deficiency

scientific article

Factor XIII Val34Leu is a genetic factor involved in the etiology of venous thrombosis

scientific article published on 01 May 1999

Fentanyl-fluanisone-midazolam combination results in more stable hemodynamics than does urethane alpha-chloralose and 2,2,2-tribromoethanol in mice

scientific article published in May 2002

Formation of platelet-binding von Willebrand factor strings on non-endothelial cells

scientific article published in October 2012

Four times cancer

scientific article published on 13 June 2018

Free and Total Protein S Antigen Levels on the Risk of Venous Thrombosis: Results From the MEGA Study ⬇️

scholarly article

Freeloading in biomedical research

scholarly article

Functional thrombomodulin deficiency causes enhanced thrombus growth in a murine model of carotid artery thrombosis

scientific article

Fundamental

scientific article

Gene Expression Profiling Identifies C/EBPδ as a Candidate Regulator of Endotoxin-induced Disseminated Intravascular Coagulation

article

Gene variants associated with deep vein thrombosis

scientific article published on 01 March 2008

Gene variants associated with venous thrombosis: confirmation in the MEGA study

scientific article published on 30 January 2010

Genetic studies in complex disease

Genetic variants associated with deep vein thrombosis: the F11 locus

scientific article published on 06 July 2009

Genetic variants of F11, statin use and venous thrombosis ⬇️

scientific article published on 01 June 2011

Genetic variation in the first-pass metabolism of ethinylestradiol, sex hormone binding globulin levels and venous thrombosis risk

scientific article published on 31 May 2017

Genetic variations associated with recurrent venous thrombosis

scientific article published on 10 September 2014

Genetics of venous thrombosis

scientific article

Genotypic variation in the promoter region of the protein C gene is associated with plasma protein C levels and thrombotic risk

scientific article published on 01 February 1995

Geographic distribution of the 20210 G to A prothrombin variant

scientific article published on 01 April 1998

Glittering prizes

scientific article published on 08 January 2017

Going abroad

scientific article published on 17 September 2016

Gross deletions/duplications in PROS1 are relatively common in point mutation-negative hereditary protein S deficiency.

scientific article published on 23 May 2009

Haemophilia B Leyden: the effect of mutations at position +13 on the liver-specific transcription of the factor IX gene

scientific article published in June 1994

Haplotypes of VKORC1, NQO1 and GGCX, their effect on activity levels of vitamin K-dependent coagulation factors, and the risk of venous thrombosis ⬇️

scientific article published on July 28, 2011

Haplotypes of the interleukin-1 receptor antagonist gene, interleukin-1 receptor antagonist mRNA levels and the risk of myocardial infarction

scientific article published on 09 July 2008

Heerlen polymorphism of protein S, an immunologic polymorphism due to dimorphism of residue 460.

scientific article

Hemophilia B Leyden: substitution of thymine for guanine at position -21 results in a disruption of a hepatocyte nuclear factor 4 binding site in the factor IX promoter

scientific article

Hereditary antithrombin deficiency: heterogeneity of the molecular basis and mortality in Dutch families

scientific article published on 01 December 1994

High factor VIIa levels do not promote tumor metastasis

scientific article published on 01 April 2008

High hematocrit as a risk factor for venous thrombosis. Cause or innocent bystander?

scientific article published on February 2010

High levels of coagulation factors and venous thrombosis risk: strongest association for factor VIII and von Willebrand factor

scientific article published on 18 December 2018

High levels of protein C are determined byPROCRhaplotype 3

scientific article published on 01 May 2011

High risk of thrombosis in patients homozygous for factor V Leiden (activated protein C resistance)

scientific article published on 01 March 1995

High throughput mRNA profiling highlights associations between myocardial infarction and aberrant expression of inflammatory molecules in blood cells

scientific article published on 02 November 2004

Homozygous protein S deficiency due to a one base pair deletion that leads to a stop codon in exon III of the protein S gene

scientific article published on 01 June 1994

Human protein S cDNA encodes Phe-16 and Tyr 222 in consensus sequences for the post-translational processing

scientific article

Hyperglycemia accelerates arterial thrombus formation and attenuates the antithrombotic response to endotoxin in mice

scientific article published in October 2007

Hyperhomocysteinemia as a risk factor for deep-vein thrombosis

scientific article published in March 1996

Identification of eight point mutations in protein S deficiency type I--analysis of 15 pedigrees

scientific article published on 01 May 1995

Identification of polymorphisms in the 5'-untranslated region of the TAFI gene: relationship with plasma TAFI levels and risk of venous thrombosis

scientific article published on 01 May 2001

Increased risk of venous thrombosis in carriers of hereditary protein C deficiency defect

scientific article

Increased risk of venous thrombosis in oral-contraceptive users who are carriers of factor V Leiden mutation

scientific article published on November 1994

Inflammatory cytokines as risk factors for a first venous thrombosis: a prospective population-based study

scientific article

Inherited prethrombotic disorders and infectious purpura

scientific article published on 01 June 1996

Instability of repeats of the von Willebrand factor gene variable number tandem repeat sequence in intron 40

scientific article published on 01 July 1993

Interleukin 8 and venous thrombosis: evidence for a role of inflammation in thrombosis

scientific article published in January 2002

Intracellular storage and regulated secretion of von Willebrand factor in quantitative von Willebrand disease

scientific article published on 19 May 2011

Is administering blood as useless as blood letting?

scientific article published in October 2013

Is there also room for rational thought?

scientific article published on 18 November 2017

Karl Landsteiner

scientific article published on 18 May 2018

Know and act

scientific article published on 06 May 2016

Linking

scientific article

Location on the human genetic linkage map of 26 genes involved in blood coagulation

scientific article published on 01 May 1997

Long-term thrombin inhibition promotes cancer cell extravasation in a mouse model of experimental metastasis

scientific article published on 24 June 2009

Lots and lots of women

scientific article published on 19 April 2018

Love thy neighbors

scientific article published on 14 February 2015

Low molecular weight heparin attenuates multiple organ failure in a murine model of disseminated intravascular coagulation

scientific article published in June 2005

Major Haemorrhage during Vitamin K Antagonist Treatment: The Influence of Thyroid Hormone Levels.

scientific article published on 28 February 2014

March editorial

scientific article published in March 2013

Mature

scientific article published on 03 August 2015

May editorial

scientific article published on 01 May 2013

Meta-analysis

scientific article published on 19 June 2014

Meta-analysis of 65,734 individuals identifies TSPAN15 and SLC44A2 as two susceptibility loci for venous thromboembolism

scientific article

Modified two-step model for studying the inflammatory response during myocardial ischemia and reperfusion in mice.

scientific article published on October 2003

More kudos

article

MspI RFLP in intron 8 of the human protein C gene

scientific article published on October 1989

Multiple SNP testing improves risk prediction of first venous thrombosis

scientific article published on 14 May 2012

Multiple substitutions in the von Willebrand factor gene that mimic the pseudogene sequence.

scientific article

Murine tissue factor coagulant activity is critically dependent on the presence of an intact allosteric disulfide.

scientific article

Mutation goes global

scientific article published on 13 April 2015

Mutation in blood coagulation factor V associated with resistance to activated protein C.

scientific article

Mutations in hemophilia Bm occur at the Arg180-Val activation site or in the catalytic domain of factor IX.

scientific article

Mutations in severe, type III von Willebrand's disease in the Dutch population: candidate missense and nonsense mutations associated with reduced levels of von Willebrand factor messenger RNA

scientific article published on 01 October 1992

Myocardial Infarction in Young Women in Relation to Plasma Total Homocysteine, Folate, and a Common Variant in the Methylenetetrahydrofolate Reductase Gene ⬇️

scientific article published on July 15, 1997

Neighborhood watch

scientific article

New editorial crew

scientific article

No P Please

scientific article published on 01 August 2016

No evidence for a direct effect of von Willebrand factor's ABH blood group antigens on von Willebrand factor clearance.

scientific article

Novel human pathological mutations. Gene symbol: PROS1. Disease: Protein S deficiency

article

Open, open, open

scientific article published in February 2018

Out of the box

scientific article published on 18 December 2016

PTX3 predicts severe disease in febrile patients at the emergency department

scientific article published on 2 December 2009

Partial protein S gene deletion in a family with hereditary thrombophilia

scientific article published on 01 February 1989

Partial reconstitution of factor VIII activity from a mild Crm+ hemophilia A patient by replacement of the defective A2 domain

scientific article published on 01 May 1998

Past and future of genetic research in thrombosis

scientific article published on July 2007

Polymorphisms in the protein C gene as risk factor for venous thrombosis

scientific article published on 01 January 2009

Predators

scientific article published on 12 August 2018

Prediction

scientific article published on 22 September 2015

Predictors and causes

scientific article published on 01 April 2018

Prevalence of protein C deficiency in the healthy population

scientific article

Protease-activated receptor (PAR)2, but not PAR1, is involved in collateral formation and anti-inflammatory monocyte polarization in a mouse hind limb ischemia model.

scientific article

Protease-activated receptor-4 inhibition protects from multiorgan failure in a murine model of systemic inflammation

scientific article published on 19 July 2007

Protein C deficiency in a controlled series of unselected outpatients: an infrequent but clear risk factor for venous thrombosis (Leiden Thrombophilia Study)

scientific article published in May 1995

Protein C deficiency: a database of mutations, 1995 update. On behalf of the Subcommittee on Plasma Coagulation Inhibitors of the Scientific and Standardization Committee of the ISTH

scientific article published on 01 May 1995

Protein C deficiency: a database of mutations. For the Protein C & S Subcommittee of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis

scientific article published on 01 January 1993

Protein S deficiency: a database of mutations--summary of the first update

article by S Gandrille et al published November 2000 in Thrombosis and Haemostasis

Protein S deficiency: a database of mutations. For the Plasma Coagulation Inhibitors Subcommittee of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis

scholarly article by S Gandrille et al published June 1997 in Thrombosis and Haemostasis

Protein S levels and the risk of venous thrombosis: results from the MEGA case-control study

scientific article published on 06 September 2013

Publication stratification

scientific article published in April 2014

Questions, questions, questions...

scientific article published on 30 August 2014

RFLP for the human prothrombin (F2) gene

scientific article published on October 1990

Race

scientific article published on 12 May 2017

Ranking the stars

scientific article published on 01 October 2018

Recessive inheritance of von Willebrand's disease type I

scientific article published on 01 April 1993

Renal tissue factor expression is increased in streptozotocin-induced diabetic mice

scientific article published on 30 June 2005

Reproducibility

scientific article published on 24 April 2017

Resistance to activated protein C and factor V Leiden as risk factors for venous thrombosis

scientific article published on 01 July 1995

Risk factor profiles in patients with different clinical manifestations of venous thromboembolism: a focus on the factor V Leiden mutation

scientific article published on 01 October 1996

Risk of Stroke in Young Women and Two Prothrombotic Mutations: Factor V Leiden and Prothrombin Gene Variant (G20210A) ⬇️

scientific article published on 01 March 1998

Scope

scientific article published on 14 February 2018

Screening for mutations in haemophilia A patients by multiplex PCR-SSCP, Southern blotting and RNA analysis: the detection of a genetic abnormality in the factor VIII gene in 30 out of 35 patients

scientific article published in June 1995

Seeming homozygosity in type-IIB von Willebrand's disease due to a polymorphism within the sequence of a commonly used primer

scientific article published on 01 March 1994

Set the record straight

scientific article published on 15 June 2015

Single nucleotide variants in the protein C pathway and mortality in dialysis patients

scientific article

Starred

scientific article published on 25 November 2015

Statins and Risk of Bleeding: An Analysis to Evaluate Possible Bias Due to Prevalent Users and Healthy User Aspects

scientific article published on 18 April 2016

Statistically speaking

scientific article published on 01 April 2015

Storage and secretion of naturally occurring von Willebrand factor A domain variants

scientific article published on 08 August 2014

Studies of the interaction between human protein S and human C4b-binding protein using deletion variants of recombinant human protein S

scientific article published on 01 April 1994

Summertime

scientific article published on 20 July 2018

Suspected survivor bias in case-control studies: stratify on survival time and use a negative control

scientific article published on 17 August 2013

Symbols

scientific article published on 25 September 2017

TF:FVIIa-specific activation of CREB upregulates proapoptotic proteins via protease-activated receptor-2.

scientific article published on 19 July 2008

Terminated

scientific article published on 01 June 2014

The 4G/5G polymorphism in the plasminogen activator inhibitor-1 gene is not associated with myocardial infarction

scientific article published on 01 July 1999

The effect of different hormonal contraceptives on plasma levels of free protein S and free TFPI

scientific article published on 14 February 2013

The good and the bad

scientific article published on 19 October 2015

The human protein S locus: identification of the PS alpha gene as a site of liver protein S messenger RNA synthesis

scientific article

The in vivo kinetics of tissue factor messenger RNA expression during human endotoxemia: relationship with activation of coagulation

scientific article published on 01 July 2000

The inheritance and molecular genetics of von Willebrand's disease

scientific article

The interaction of protein S with the phospholipid surface is essential for the activated protein C-independent activity of protein S

scientific article published on 01 September 1996

The issue contains a healthy mix of reviews, original fundamental and clinical articles, and letters to the editor covering the full spectrum of thrombosis and hemostasis that our readership is accustomed to expect

scientific article published in June 2013

The last post

scientific article published on 01 December 2018

The mutational demography of protein C deficiency

scientific article published on 01 August 1995

The relationship between ABO blood group and the risk of bleeding during vitamin K antagonist treatment

scientific article published on 01 June 2006

The spectrum of genetic defects in a panel of 40 Dutch families with symptomatic protein C deficiency type I: heterogeneity and founder effects

scientific article published on August 1991

The state of JTH.

scientific article published on 19 February 2016

The transcendental scientist

scientific article published on 12 October 2016

The usefulness of single-strand DNA conformation polymorphism analysis to detect mutations in protein C deficiency ⬇️

scientific article published on 01 November 1997

Thermolabile methylenetetrahydrofolate reductase and factor V Leiden in the risk of deep-vein thrombosis

scientific article published on 01 February 1998

Three novel mutations in five unrelated subjects with hereditary protein S deficiency type I.

scientific article

Thrombomodulin mutant mice with a strongly reduced capacity to generate activated protein C have an unaltered pulmonary immune response to respiratory pathogens and lipopolysaccharide

scientific article published on 30 October 2003

Thrombosis unfurry

scientific article published on 01 October 2014

Tissue factor expression during monocyte-macrophage differentiation

scientific article published on 01 June 1997

To the core

scientific article published on 11 January 2016

Twelve novel and two recurrent mutations in 14 Austrian families with hereditary protein C deficiency

scientific article published on 01 April 1993

Two RFLPS approximately 7 kb 5' of the human protein C gene

scientific article published on December 1988

Two genes homologous with human protein S cDNA are located on chromosome 3

scientific article published on 01 December 1987

Two mutations of the factor IX gene including a donor splice consensus deletion and a point mutation in a Dutch patient with severe hemophilia B

scientific article published on 01 November 1990

Two novel point mutations correlate with an altered developmental expression of blood coagulation factor IX (hemophilia B Leyden phenotype).

scientific article

Type I Protein C Deficiency Caused by Disruption of a Hepatocyte Nuclear Factor (HNF)-6/HNF-1 Binding Site in the Human Protein C Gene Promoter ⬇️

scientific article published on April 24, 1998

Updated analysis of gene variants associated with deep vein thrombosis

scientific article published in February 2010

What do they know?

scientific article

Whole exome sequencing in thrombophilic pedigrees to identify genetic risk factors for venous thromboembolism.

scientific article published on 8 November 2017

Winter studies.

scientific article

Words, words, words

scientific article published on 01 November 2013

Young and early

scientific article published on 02 July 2016

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