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List of works by Hans Morreau

(Secondary) solid tumors in thyroid cancer patients treated with the multi-kinase inhibitor sorafenib may present diagnostic challenges

scientific article published on 19 January 2016

A cell-free assay for the functional analysis of variants of the mismatch repair protein MLH1.

scientific article published in March 2010

A procedure for the detection of linkage with high density SNP arrays in a large pedigree with colorectal cancer

scientific article

Activation of the PI3K/AKT pathway induces urothelial carcinoma of the renal pelvis: identification in human tumors and confirmation in animal models

scientific article

Allelic variation at the 8q23.3 colorectal cancer risk locus functions as a cis-acting regulator of EIF3H.

scientific article

Automated analysis of multiple sections for the detection of occult cells in lymph nodes.

scientific article

Automatic generic registration of mass spectrometry imaging data to histology using nonlinear stochastic embedding

scientific article

Benefit of Surveillance for Pancreatic Cancer in High-Risk Individuals: Outcome of Long-Term Prospective Follow-Up Studies From Three European Expert Centers

scientific article published on 25 April 2016

Challenges and Pitfalls in the Management of Parathyroid Carcinoma: 17-Year Follow-Up of a Case and Review of the Literature ⬇️

scientific article published on November 19, 2010

Chromosomal instability in MYH- and APC-mutant adenomatous polyps

scientific article published in March 2006

Colorectal carcinomas in MUTYH-associated polyposis display histopathological similarities to microsatellite unstable carcinomas

scientific article published on 15 June 2009

Combined mismatch repair and POLE/POLD1 defects explain unresolved suspected Lynch syndrome cancers

scientific article

Conventional and tissue microarray immunohistochemical expression analysis of mismatch repair in hereditary colorectal tumors

scientific article published on February 2003

Copy number alterations and allelic ratio in relation to recurrence of rectal cancer

scientific article published on 6 June 2015

Cross-species comparison of human and mouse intestinal polyps reveals conserved mechanisms in adenomatous polyposis coli (APC)-driven tumorigenesis

scientific article

Development of sporadic microsatellite instability in colorectal tumors involves hypermethylation at methylated-in-tumor loci in adenoma

scientific article

Diagnostic approach and management of Lynch syndrome (hereditary nonpolyposis colorectal carcinoma): a guide for clinicians

scientific article published on July 2006

Diagnostic value of targeted next-generation sequencing in patients with suspected pancreatic or periampullary cancer.

scientific article published on 3 August 2017

Dilemmas in the management of screen-detected lesions in patients at high risk for pancreatic cancer

scientific article published on 12 July 2016

Double NF1 inactivation affects adrenocortical function in NF1Prx1 mice and a human patient

scientific article

Early onset MSI-H colon cancer with MLH1 promoter methylation, is there a genetic predisposition?

scientific article

Genes differentially expressed in thyroid carcinoma identified by comparison of SAGE expression profiles

scientific article published on 8 January 2004

Genome haploidisation with chromosome 7 retention in oncocytic follicular thyroid carcinoma.

scientific article

Genomic profiling by DNA amplification of laser capture microdissected tissues and array CGH

scientific article published on 28 October 2004

Genomic profiling reveals mutational landscape in parathyroid carcinomas

scientific article

Germline variants in POLE are associated with early onset mismatch repair deficient colorectal cancer

scientific article

HNPCC versus sporadic microsatellite-unstable colon cancers follow different routes toward loss of HLA class I expression.

scientific article published on 22 February 2007

High-resolution analysis of HLA class I alterations in colorectal cancer.

scientific article

High-resolution copy number analysis of paraffin-embedded archival tissue using SNP BeadArrays.

scientific article

High-resolution melting (HRM) re-analysis of a polyposis patients cohort reveals previously undetected heterozygous and mosaic APC gene mutations.

scientific article published on June 2015

Identification of familial colorectal cancer and hereditary colorectal cancer syndromes through the Dutch population-screening program: results ofa pilot study

scientific article published on 16 June 2016

Integral analysis of p53 and its value as prognostic factor in sporadic colon cancer

scientific article

Integrating chromosomal aberrations and gene expression profiles to dissect rectal tumorigenesis

scientific article

Limitations of Tc99m‐MIBI‐SPECT Imaging Scans in Persistent Primary Hyperparathyroidism ⬇️

scientific article published on January 1, 2011

Low penetrance of a SDHB mutation in a large Dutch paraganglioma family

scientific article

MLPAinter for MLPA interpretation: an integrated approach for the analysis, visualisation and data management of Multiplex Ligation-dependent Probe Amplification ⬇️

scientific article

MUTYH-associated polyposis (MAP)

scientific article

MUTYH-associated polyposis carcinomas frequently lose HLA class I expression - a common event amongst DNA-repair-deficient colorectal cancers

scientific article published in September 2009

Magnetic resonance imaging surveillance detects early-stage pancreatic cancer in carriers of a p16-Leiden mutation

scientific article published in December 2010

Mass spectrometry-based loss of heterozygosity analysis of single-nucleotide polymorphism loci in paraffin embedded tumors using the MassEXTEND assay: single-nucleotide polymorphism loss of heterozygosity analysis of the protein tyrosine phosphatase

scientific article published on November 2005

MicroRNA classifier and nomogram for metastasis prediction in colon cancer.

scientific article

Molecular analysis of hereditary nonpolyposis colorectal cancer in the United States: high mutation detection rate among clinically selected families and characterization of an American founder genomic deletion of the MSH2 gene

scientific article

Pancreatic carcinoma in carriers of a specific 19 base pair deletion of CDKN2A/p16 (p16-leiden).

scientific article published on September 2003

Prognostic Impact of Urokinase Plasminogen Activator Receptor Expression in Pancreatic Cancer: Malignant Versus Stromal Cells.

scientific article

Prognostic and predictive biomarkers in resected colon cancer: current status and future perspectives for integrating genomics into biomarker discovery

scientific article published on 29 March 2010

Prognostic value of HLA class I, HLA-E, HLA-G and Tregs in rectal cancer: a retrospective cohort study

scientific article

Rapid KRAS, EGFR, BRAF and PIK3CA mutation analysis of fine needle aspirates from non-small-cell lung cancer using allele-specific qPCR.

scientific article

Recurrent Coding Sequence Variation Explains Only A Small Fraction of the Genetic Architecture of Colorectal Cancer ⬇️

scientific article

Refinement of the associations between risk of colorectal cancer and polymorphisms on chromosomes 1q41 and 12q13.13

scientific article published on 10 November 2011

Selecting Tumor-Specific Molecular Targets in Pancreatic Adenocarcinoma: Paving the Way for Image-Guided Pancreatic Surgery

scientific article published on 29 April 2016

Specific genomic aberrations in primary colorectal cancer are associated with liver metastases

scientific article

Survival of MUTYH-associated polyposis patients with colorectal cancer and matched control colorectal cancer patients

scientific article

Targeted next-generation sequencing of FNA-derived DNA in pancreatic cancer

scientific article published on 26 September 2016

The bone morphogenetic protein pathway is inactivated in the majority of sporadic colorectal cancers

scientific article

The colorectal cancer risk at 18q21 is caused by a novel variant altering SMAD7 expression

scientific article

Toward optical guidance during endoscopic ultrasound-guided fine needle aspirations of pancreatic masses using single fiber reflectance spectroscopy: a feasibility study

scientific article published in February 2017

Towards imaging metabolic pathways in tissues.

scientific article

Validation of full-field optical coherence tomography in distinguishing malignant and benign tissue in resected pancreatic cancer specimens

scientific article

Variation in precursor lesions of pancreatic cancer among high-risk groups

scientific article published on 21 November 2012

Whole Gene Capture Analysis of 15 CRC Susceptibility Genes in Suspected Lynch Syndrome Patients.

scientific article

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