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List of works by Tom Huizinga

2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative

scholarly article by Daniel Aletaha et al published 10 August 2010 in Arthritis and Rheumatism

2010 rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative

scientific article

A European perspective on the 50th anniversary of Arthritis & Rheumatism

scientific article published on February 2008

A Novel Role of Complement Factor C1q in Augmenting the Presentation of Antigen Captured in Immune Complexes to CD8+ T Lymphocytes

article

A candidate gene approach identifies the TRAF1/C5 region as a risk factor for rheumatoid arthritis

scientific article

A clinical pharmacogenetic model to predict the efficacy of methotrexate monotherapy in recent-onset rheumatoid arthritis

article

A comparison between the simplified erosion and narrowing score and the Sharp–van der Heijde score: post hoc analysis from the BeSt study ⬇️

scientific article published on December 14, 2010

A genetic study on C5-TRAF1 and progression of joint damage in rheumatoid arthritis

scientific article

A genetic variant in osteoprotegerin is associated with progression of joint destruction in rheumatoid arthritis

scientific article

A large-scale rheumatoid arthritis genetic study identifies association at chromosome 9q33.2.

scientific article

A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases

scientific article

A multi-biomarker score measures rheumatoid arthritis disease activity in the BeSt study ⬇️

scientific article published on 07 February 2013

A multibiomarker disease activity score for rheumatoid arthritis predicts radiographic joint damage in the BeSt study.

scientific article published on 15 August 2014

A multimodal MRI approach to identify and characterize microstructural brain changes in neuropsychiatric systemic lupus erythematosus

scientific article published on 16 May 2015

A prediction model for progressive disease in systemic sclerosis

scientific article

A prediction rule for disease outcome in patients with Recent-onset undifferentiated arthritis: How to guide individual treatment decisions

scientific article published on 01 February 2007

A two-step treatment strategy trial in patients with early arthritis aimed at achieving remission: the IMPROVED study ⬇️

scientific article published on May 28, 2013

ACPA-negative RA consists of subgroups: patients with high likelihood of achieving sustained DMARD-free remission can be identified by serological markers at disease presentation

scientific article published on 14 May 2019

ASAS modification of the Berlin algorithm for diagnosing axial spondyloarthritis: results from the SPondyloArthritis Caught Early (SPACE)-cohort and from the Assessment of SpondyloArthritis international Society (ASAS)-cohort

scientific article published on 8 November 2012

Abatacept decreases disease activity in a absence of CD4(+) T cells in a collagen-induced arthritis model.

scientific article

Ability of Interleukin-33- and Immune Complex-Triggered Activation of Human Mast Cells to Down-Regulate Monocyte-Mediated Immune Responses

article

Abnormal brain diffusivity in patients with neuropsychiatric systemic lupus erythematosus ⬇️

scientific article published on May 1, 2003

Accelerated hand bone mineral density loss is associated with progressive joint damage in hands and feet in recent-onset rheumatoid arthritis

scientific article

Acitretin-related ossification

scientific article published on 01 April 2007

Activation of human basophils by combined toll-like receptor- and FcεRI-triggering can promote Th2 skewing of naive T helper cells

scientific article published on 13 November 2013

Activation of receptor for advanced glycation end products in osteoarthritis leads to increased stimulation of chondrocytes and synoviocytes

scientific article published in January 2006

Adipocyte-derived lipids modulate CD4+ T-cell function

scientific article published on 24 April 2013

Adipocytes modulate the phenotype of human macrophages through secreted lipids

scientific article published in July 2013

Adoptive transfer of IL-10-secreting CD4+CD49b+ regulatory T cells suppresses ongoing arthritis

scientific article published on 31 October 2009

Advances in the genetics of rheumatoid arthritis point to subclassification into distinct disease subsets

scientific article published on 31 March 2008

Aiming for a shorter rheumatoid arthritis MRI protocol: can contrast-enhanced MRI replace T2 for the detection of bone marrow oedema?

scientific article published on 28 June 2014

Aiming for a simpler early arthritis MRI protocol: can Gd contrast administration be eliminated?

scientific article

Allele-dose association of the C5orf30 rs26232 variant with joint damage in rheumatoid arthritis

scientific article published in October 2013

Allele-specific expression of the IL-1 alpha gene in human CD4+ T cell clones.

scientific article

An evaluation of molecular and clinical remission in rheumatoid arthritis by assessing radiographic progression

scientific article published on 3 January 2013

An evidence-based approach to pre-pregnancy counselling for patients with systemic lupus erythematosus

scientific article published on 20 November 2017

An extended HLA-DQ-DR haplotype rather than DRB1 alone contributes to RA predisposition ⬇️

scientific article published on November 1, 1998

An independent role of protective HLA class II alleles in rheumatoid arthritis severity and susceptibility

scientific article published on 01 September 2005

An innovative care model coordinated by a physical therapist and nurse practitioner for osteoarthritis of the hip and knee in specialist care: a prospective study

scientific article published on 17 January 2013

An investigation of the added value of an ACPA multiplex assay in an early rheumatoid arthritis setting.

scientific article

An overview of autoantibodies in rheumatoid arthritis

scientific article published on 03 January 2020

Analysis of allelic expression patterns of IL-2, IL-3, IL-4, and IL-13 in human CD4+ T cell clones

scientific article published on 01 August 2003

Animal models for arthritis: innovative tools for prevention and treatment

scientific article published on 30 May 2011

Anti-C1q receptor/calreticulin autoantibodies in patients with systemic lupus erythematosus (SLE) ⬇️

scientific article published on February 1, 1998

Anti-CarP antibodies in two large cohorts of patients with rheumatoid arthritis and their relationship to genetic risk factors, cigarette smoking and other autoantibodies.

scientific article published on 8 May 2014

Anti-carbamylated protein (anti-CarP) antibodies precede the onset of rheumatoid arthritis

scientific article published on 13 December 2013

Anti-carbamylated protein antibodies are present in arthralgia patients and predict the development of rheumatoid arthritis

scientific article published in April 2013

Anti-carbamylated protein antibodies are present prior to rheumatoid arthritis and are associated with its future diagnosis.

scientific article

Anti-carbamylated protein antibodies in rheumatoid arthritis patients of Asian descent: Fig. 1

article

Anti-citrullinated protein antibodies (ACPA) in early rheumatoid arthritis.

scientific article published on 06 July 2011

Anti-citrullinated protein antibodies acquire a pro-inflammatory Fc glycosylation phenotype prior to the onset of rheumatoid arthritis

scientific article published on 08 October 2013

Anti-citrullinated protein antibodies contribute to platelet activation in rheumatoid arthritis.

scientific article

Anti-cyclic citrullinated peptide antibodies are a collection of anti-citrullinated protein antibodies and contain overlapping and non-overlapping reactivities

scientific article published on 24 August 2010

Antibodies specific for carbamylated proteins precede the onset of clinical symptoms in mice with collagen induced arthritis

scientific article

Antibodies to Porphyromonas gingivalis Are Associated with Anticitrullinated Protein Antibodies in Patients with Rheumatoid Arthritis and Their Relatives

scientific article published on 01 May 2010

Antibodies to citrullinated proteins and differences in clinical progression of rheumatoid arthritis

scientific article

Anticytomegalovirus seropositivity in rheumatoid arthritis is not associated with the presence of severe extraarticular complications: comment on the article by Pierer et al.

scientific article published in August 2012

Antigen-specific immunomodulation of collagen-induced arthritis with tumor necrosis factor-stimulated dendritic cells

scientific article published on 01 October 2004

Are baseline high molecular weight adiponectin levels associated with radiographic progression in rheumatoid arthritis and osteoarthritis?

scientific article published in April 2014

Are rheumatoid arthritis patients discernible from other early arthritis patients using 1.5T extremity magnetic resonance imaging? a large cross-sectional study

scientific article published on 15 July 2014

Arthrography in loosened hip prostheses. Assessment of possibilities for intra-articular therapy

scientific article published on 4 January 2006

Aspects of early arthritis. Definition of disease states in early arthritis: remission versus minimal disease activity

scientific article published on January 2006

Assessment of global disease activity in RA patients monitored in the METEOR database: the patient's versus the rheumatologist's opinion

scientific article published on 26 September 2013

Association between HLA class II genes and autoantibodies to cyclic citrullinated peptides (CCPs) influences the severity of rheumatoid arthritis

article

Association between centromere and topoisomerase specific immune responses and the degree of microangiopathy in Systemic Sclerosis

scientific article published on 01 June 2020

Association between leptin, adiponectin and resistin and long-term progression of hand osteoarthritis

scientific article published on 6 April 2011

Association between microscopic brain damage as indicated by magnetization transfer imaging and anticardiolipin antibodies in neuropsychiatric lupus

scientific article

Association between several clinical and radiological determinants with long-term clinical progression and good prognosis of lower limb osteoarthritis

scientific article (publication date: 2011)

Association between weight or body mass index and hand osteoarthritis: a systematic review

scientific article published on 31 May 2009

Association of HLA-DR3 with anti-cyclic citrullinated peptide antibody-negative rheumatoid arthritis

scientific article published on October 2005

Association of a haplotype in the promoter region of the interferon regulatory factor 5 gene with rheumatoid arthritis

article

Association of a single-nucleotide polymorphism in CD40 with the rate of joint destruction in rheumatoid arthritis

scientific article

Association of autoantibodies to glucose-6-phosphate isomerase with extraarticular complications in rheumatoid arthritis

scientific article published in February 2004

Association of the 6q23 region with the rate of joint destruction in rheumatoid arthritis

scientific article

Association of the interleukin-1 gene cluster with radiographic signs of osteoarthritis of the hip.

scientific article published in April 2004

Association of the risk of osteoarthritis with high innate production of interleukin-1beta and low innate production of interleukin-10 ex vivo, upon lipopolysaccharide stimulation

scientific article published on 01 May 2005

Association with joint damage and physical functioning of nine composite indices and the 2011 ACR/EULAR remission criteria in rheumatoid arthritis ⬇️

scientific article published on August 3, 2011

Associations, populations, and the truth: recommendations for genetic association studies in Arthritis & Rheumatism

scientific article published in July 2004

Auto-antibodies and cancer in systemic sclerosis

scientific article published on 29 May 2017

Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage.

scientific article

Autoantibody Development under Treatment with Immune-Checkpoint Inhibitors

scientific article published on 13 November 2018

Autoantibody status is not associated with early treatment response to first-line methotrexate in patients with early rheumatoid arthritis

scientific article published on 01 January 2019

Autoimmune responses in the rheumatoid synovium.

scientific article

Autoimmunity in rheumatoid arthritis: different antigens--common principles

scientific article published on 19 December 2012

Autoimmunity: break-through in the diagnosis and treatment of immune-mediated inflammatory diseases

scientific article published on 19 October 2014

Autonomous online health assessment questionnaire registry in daily clinical practice

scientific article

B-cell receptor sequencing of anti-citrullinated protein antibody (ACPA) IgG-expressing B cells indicates a selective advantage for the introduction of N-glycosylation sites during somatic hypermutation

scientific article published on 23 August 2017

Baseline autoantibody profile in rheumatoid arthritis is associated with early treatment response but not long-term outcomes.

scientific article published on 26 February 2018

Baseline serum adipokine levels predict radiographic progression in early rheumatoid arthritis

scientific article published on 01 September 2011

Belimumab after rituximab as maintenance therapy in lupus nephritis

scientific article published on 08 September 2014

Biologic and oral disease-modifying antirheumatic drug monotherapy in rheumatoid arthritis

scientific article

Blood pressure changes in patients with recent-onset rheumatoid arthritis treated with four different treatment strategies: a post hoc analysis from the BeSt trial

scientific article published on 14 May 2010

Body mass index and extent of MRI-detected inflammation: opposite effects in rheumatoid arthritis versus other arthritides and asymptomatic persons

scientific article published on 22 October 2016

Brain histopathology in patients with systemic lupus erythematosus: identification of lesions associated with clinical neuropsychiatric lupus syndromes and the role of complement

scientific article published on 25 October 2016

Brain involvement in rheumatoid arthritis: a magnetic resonance spectroscopy study

scientific article published in November 2009

Breach of autoreactive B cell tolerance by post-translationally modified proteins

scientific article published on 25 April 2017

Brief Report: Clinical Trials Aiming to Prevent Rheumatoid Arthritis Cannot Detect Prevention Without Adequate Risk Stratification: A Trial of Methotrexate Versus Placebo in Undifferentiated Arthritis as an Example

scientific article published on 19 February 2017

Brief Report: The Role of Rare Protein-Coding Variants in Anti-Tumor Necrosis Factor Treatment Response in Rheumatoid Arthritis.

scientific article

CTLA4 is differentially associated with autoimmune diseases in the Dutch population

CTLA4 is differently associated with autoimmune diseases in the Dutch population

Can anti-cyclic citrullinated peptide antibody-negative RA be subdivided into clinical subphenotypes?

scientific article published on 27 October 2011

Carbamylation and antibodies against carbamylated proteins in autoimmunity and other pathologies

scientific article published on 28 October 2013

Cerebral magnetic resonance imaging in quiescent Crohn's disease patients with fatigue

scientific article

Changes in hand bone mineral density and the association with the level of disease activity in patients with rheumatoid arthritis: Bone mineral density measurements in a multicenter randomized clinical trial ⬇️

scientific article published on December 1, 2011

Characterising arthralgia in the preclinical phase of rheumatoid arthritis using MRI

scientific article published on 09 April 2014

Circulating calprotectin (S100A8/A9) is higher in rheumatoid arthritis patients that relapse within 12 months of tapering anti-rheumatic drugs

scientific article published on 05 December 2019

Circulating plasmablasts/plasmacells as a source of anticitrullinated protein antibodies in patients with rheumatoid arthritis

scientific article published on 26 April 2013

Clinical and radiological outcomes of 5-year drug-free remission-steered treatment in patients with early arthritis: IMPROVED study

scientific article

Clinical factors, anticitrullinated peptide antibodies and MRI-detected subclinical inflammation in relation to progression from clinically suspect arthralgia to arthritis

scientific article published on 27 November 2015

Clinical pharmacogenetic model to predict response of MTX monotherapy in patients with established rheumatoid arthritis after DMARD failure

scientific article published in July 2012

Clustering of hand osteoarthritis progression and its relationship to progression of osteoarthritis at the knee

scientific article published on 23 February 2013

Comment on: Investigation of candidate polymorphisms and disease activity in rheumatoid arthritis patients on methotrexate

scientific article published on 13 July 2009

Common variants at CD40 and other loci confer risk of rheumatoid arthritis

scientific article published on 14 September 2008

Communication between human mast cells and CD4(+) T cells through antigen-dependent interactions

scientific article published on 13 May 2013

Comparative Efficacy of Novel DMARDs as Monotherapy and in Combination with Methotrexate in Rheumatoid Arthritis Patients with Inadequate Response to Conventional DMARDs: A Network Meta-Analysis

scientific article published on May 2015

Comparison between low disease activity or DAS remission as treatment target in patients with early active rheumatoid arthritis.

scientific article published on 20 May 2018

Confirmation of STAT4, IL2/IL21, and CTLA4 polymorphisms in rheumatoid arthritis

scientific article published in May 2009

Continued participation in a ten-year tight control treat-to-target study in rheumatoid arthritis: why keep patients doing their best?

scientific article published on May 2015

Control of systemic B cell-mediated autoimmune disease by nonmyeloablative conditioning and major histocompatibility complex-mismatched allogeneic bone marrow transplantation

scientific article published on 16 December 2004

Conversion to seronegative status after abatacept treatment in patients with early and poor prognostic rheumatoid arthritis is associated with better radiographic outcomes and sustained remission: post hoc analysis of the AGREE study ⬇️

scientific article published on 30 March 2018

Correction to: On-drug and drug-free remission by baseline symptom duration: abatacept with methotrexate in patients with early rheumatoid arthritis

scientific article published on 01 May 2019

Criteria for early rheumatoid arthritis: from Bayes' law revisited to new thoughts on pathogenesis

scientific article

Criteria for the selection of single nucleotide polymorphisms in pathway pharmacogenetics: TNF inhibitors as a case study

scientific article published on 12 June 2009

Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis

scientific article published on 23 August 2016

Crowdsourcing genetic prediction of clinical utility in the Rheumatoid Arthritis Responder Challenge

scientific article

Cumulative endogenous estrogen exposure is not associated with severity of peripheral microangiopathy in patients with systemic sclerosis

scientific article published on 01 July 2019

Cutting Edge: TNFR-Shedding by CD4+CD25+ Regulatory T Cells Inhibits the Induction of Inflammatory Mediators

scientific article published on 01 March 2008

DAS steered therapy in clinical practice; cross-sectional results from the METEOR database

scientific article published on 16 January 2016

DC-induced CD8(+) T-cell response is inhibited by MHC class II-dependent DX5(+)CD4(+) Treg

scientific article published in July 2009

DX5(+)CD4(+) T cells modulate cytokine production by CD4(+) T cells towards IL-10 via the production of IL-4.

scientific article published on October 2010

DX5+ CD4+ T cells modulate CD4+ T-cell response via inhibition of IL-12 production by DCs.

scientific article published in February 2013

De novo generation and enhanced suppression of human CD4+CD25+ regulatory T cells by retinoic acid

scientific article published on 28 August 2009

Defining conditions where long-term glucocorticoid treatment has an acceptably low level of harm to facilitate implementation of existing recommendations: viewpoints from an EULAR task force

scientific article published on March 2016

Degree of Vasculopathy in Systemic Sclerosis Patients with Anti-U3RNP Antibody Indicates Need for Extensive Cardiopulmonary Screening

scientific article published on 01 July 2019

Demyelinating disease in SLE: is it multiple sclerosis or lupus?

scientific article published on June 2013

Dendritic cells, but not macrophages or B cells, activate major histocompatibility complex class II-restricted CD4+ T cells upon immune-complex uptake in vivo

scientific article published on 21 September 2006

Depression and anxiety associate with less remission after 1 year in rheumatoid arthritis.

scientific article

Detection of change in CNS involvement in neuropsychiatric SLE: a magnetization transfer study

scientific article published in October 2006

Determinants of reaching drug-free remission in patients with early rheumatoid or undifferentiated arthritis after one year of remission-steered treatment

scientific article published on 15 February 2015

Different classes of anti-modified protein antibodies are induced on exposure to antigens expressing only one type of modification

scientific article published on 31 May 2019

Differential methylation within the major histocompatibility complex region in rheumatoid arthritis: a replication study

scientific article published on 30 September 2014

Differential responsiveness to immunoablative therapy in refractory rheumatoid arthritis is associated with level and avidity of anti-cyclic citrullinated protein autoantibodies: a case study

scientific article

Discontinuing treatment in patients with rheumatoid arthritis in sustained clinical remission: exploratory analyses from the BeSt study ⬇️

scientific article published on November 10, 2010

Disease activity monitoring in rheumatoid arthritis in daily practice: experiences with METEOR, a free online tool

scientific article published on 01 December 2010

Disease flares in rheumatoid arthritis are associated with joint damage progression and disability: 10-year results from the BeSt study

scientific article published on 31 August 2015

Distinct ACPA fine specificities, formed under the influence of HLA shared epitope alleles, have no effect on radiographic joint damage in rheumatoid arthritis

scientific article published on 10 June 2011

Do Comorbidities Play a Role in Hand Osteoarthritis Disease Burden? Data from the Hand Osteoarthritis in Secondary Care Cohort

scientific article published on 15 September 2017

Do knee abnormalities visualised on MRI explain knee pain in knee osteoarthritis? A systematic review

scientific article published on 09 September 2010

Dosing down with biologic therapies: a systematic review and clinicians' perspective

scientific article published on 16 February 2017

Dosing down with biologic therapies: a systematic review and clinicians' perspective.

scientific article published in March 2018

Dr. Zirkzee, et al reply

scientific article published in February 2013

Drivers of costly treatment strategies in rheumatoid arthritis

scientific article published on 17 May 2016

Drug evaluation: apratastat, a novel TACE/MMP inhibitor for rheumatoid arthritis

scientific article published on 01 November 2006

Drug therapy in undifferentiated arthritis: a systematic literature review ⬇️

scientific article published on 06 June 2013

Drug-free remission: is it already possible?

scientific article published on May 2011

EULAR recommendations for terminology and research in individuals at risk of rheumatoid arthritis: report from the Study Group for Risk Factors for Rheumatoid Arthritis

scientific article published on 2 March 2012

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs

scientific article

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update ⬇️

scientific article published on 6 March 2017

Early aggressive therapy in rheumatoid arthritis: a 'window of opportunity'?

scientific article published on 01 November 2005

Early local swelling and tenderness are associated with large-joint damage after 8 years of treatment to target in patients with recent-onset rheumatoid arthritis

scientific article published in April 2013

Early rheumatoid arthritis

scientific article published on 01 February 2009

Efficacy and safety of certolizumab pegol in a broad population of patients with active rheumatoid arthritis: results from the REALISTIC phase IIIb study

scientific article published on 25 August 2012

Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes.

scientific article published on April 2006

Efficacy of methotrexate treatment in patients with probable rheumatoid arthritis: A double-blind, randomized, placebo-controlled trial

scientific article published on 01 May 2007

Efficacy of tofacitinib monotherapy in methotrexate-naive patients with early or established rheumatoid arthritis

scientific article published on 26 July 2016

Elevated formation of pyridinoline cross-links by profibrotic cytokines is associated with enhanced lysyl hydroxylase 2b levels

scientific article published on 5 October 2004

Emerging patterns of risk factor make-up enable subclassification of rheumatoid arthritis

scientific article

Engraftment of cutaneous fibroblasts within synovial membrane in a nonhuman primate: short-term results

scientific article published on 27 November 2006

Epistasis between two HLA antigens defines a subset of individuals at a very high risk for ankylosing spondylitis

scientific article

Epitope spreading of the anti-citrullinated protein antibody response occurs before disease onset and is associated with the disease course of early arthritis

scientific article published on 6 May 2010

Erratum to: Aiming for a shorter rheumatoid arthritis MRI protocol: can contrast-enhanced MRI replace T2 for the detection of bone marrow oedema?

scientific article published on 01 March 2017

Erratum: Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis

scientific article published on 10 October 2016

Etanercept in patients with inflammatory hand osteoarthritis (EHOA): a multicentre, randomised, double-blind, placebo-controlled trial

scientific article published on 03 October 2018

Evaluating drug-free remission with abatacept in early rheumatoid arthritis: results from the phase 3b, multicentre, randomised, active-controlled AVERT study of 24 months, with a 12-month, double-blind treatment period

scientific article

Evaluating processes underlying the predictive value of baseline erosions for future radiological damage in early rheumatoid arthritis

scientific article

Evaluation of magnetic resonance imaging-detected tenosynovitis in the hand and wrist in early arthritis

scientific article published in April 2015

Evaluation of the Disease Activity Score in Twenty-Eight Joints-Based Flare Definitions in Rheumatoid Arthritis: Data From a Three-Year Clinical Trial

scientific article

Evaluation of the contribution of cumulative levels of inflammation to the variance in joint destruction in rheumatoid arthritis.

scientific article

Evaluation of the diagnostic accuracy of hand and foot MRI for early Rheumatoid Arthritis

scientific article published on 27 April 2017

Evaluation of the joint distribution at disease presentation of patients with rheumatoid arthritis: a large study across continents.

scientific article

Every shared epitope allele for itself?

scientific article published on 01 September 2009

Evidence for non-random distribution of Fcgamma receptor genotype combinations

scientific article published on 26 June 2003

Evidence for treating rheumatoid arthritis to target: results of a systematic literature search

scientific article published on April 2010

Exploratory analysis of four polymorphisms in human GGH and FPGS genes and their effect in methotrexate-treated rheumatoid arthritis patients

scientific article published on 01 February 2007

Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humans.

scientific article

Extensive glycosylation of ACPA-IgG variable domains modulates binding to citrullinated antigens in rheumatoid arthritis.

scientific article published on 13 January 2015

Family studies in the information age.

scientific article published in November 2013

Fatigue in rheumatoid arthritis; a persistent problem: a large longitudinal study

scientific article

Fc gamma receptor binding profile of anti-citrullinated protein antibodies in immune complexes suggests a role for FcγRI in the pathogenesis of synovial inflammation

scientific article published on 15 January 2018

Fc-glycosylation of IgG1 is modulated by B-cell stimuli

scientific article

Feasibility of tailored treatment based on risk stratification in patients with early rheumatoid arthritis

scientific article

Fibroblast-like synoviocytes derived from patients with rheumatoid arthritis show the imprint of synovial tissue heterogeneity: evidence of a link between an increased myofibroblast-like phenotype and high-inflammation synovitis.

scientific article

Fibroblast-like synoviocytes from rheumatoid arthritis patients express less FLICE-inhibitory protein than fibroblast-like synoviocytes from trauma patients: Comment on the article by Schedel et al

scientific article published on 01 March 2003

Fine mapping seronegative and seropositive rheumatoid arthritis to shared and distinct HLA alleles by adjusting for the effects of heterogeneity.

scientific article published on 20 March 2014

Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes

scientific article published on 17 September 2018

Fine-mapping identifies causal variants for RA and T1D in DNASE1L3, SIRPG, MEG3, TNFAIP3 and CD28/CTLA4 loci

Five-year outcomes of probable rheumatoid arthritis treated with methotrexate or placebo during the first year (the PROMPT study).

scientific article published on 19 January 2013

Frequency of functional interleukin-10 promoter polymorphism is different between relapse-onset and primary progressive multiple sclerosis

scientific article published on 01 April 2002

Functional killer Ig-like receptors on human memory CD4+ T cells specific for cytomegalovirus.

scientific article published on April 2009

Functional regulatory immune responses against human cartilage glycoprotein-39 in health vs. proinflammatory responses in rheumatoid arthritis.

scholarly article

Gene therapy and cement injection for restabilization of loosened hip prostheses

scientific article published in January 2008

Gene therapy for the treatment of hip prosthesis loosening: adverse events in a phase 1 clinical study

scientific article

Gene transfer of tissue inhibitor of metalloproteinases-3 reverses the inhibitory effects of TNF-alpha on Fas-induced apoptosis in rheumatoid arthritis synovial fibroblasts

scientific article

Gene-environment interaction influences the reactivity of autoantibodies to citrullinated antigens in rheumatoid arthritis

scientific article published on October 2010

Genetic Factors for the Severity of ACPA-negative Rheumatoid Arthritis in 2 Cohorts of Early Disease: A Genome-wide Study.

scientific article

Genetic drift as an explanation for the reduced incidence of rheumatoid arthritis

scientific article published on 01 November 2002

Genetic markers of treatment response in rheumatoid arthritis

scientific article published on October 2006

Genetic predisposition of the severity of joint destruction in rheumatoid arthritis: a population-based study.

scientific article

Genetic studies on components of the Wnt signalling pathway and the severity of joint destruction in rheumatoid arthritis

scientific article published on 5 October 2012

Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk

scientific article

Genetic variants in the prediction of rheumatoid arthritis

scientific article published on 03 May 2010

Genetics in rheumatoid arthritis

scientific article

Genetics in rheumatoid arthritis

scientific article published on 01 October 2003

Genetics of rheumatoid arthritis contributes to biology and drug discovery

scientific article

Genetics of rheumatoid arthritis: what have we learned?

scientific article published on 10 May 2011

Genome-wide association analysis of anti-TNF drug response in patients with rheumatoid arthritis

scientific article

Genome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritis

scientific article

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

scientific article

Genome-wide single-nucleotide polymorphism studies in rheumatology: hype or hope?

scientific article published on September 2008

Genomic Influences on Susceptibility and Severity of Rheumatoid Arthritis

scientific article

Glial and axonal changes in systemic lupus erythematosus measured with diffusion of intracellular metabolites.

scientific article published on 11 March 2016

Glycan profiling of anti-citrullinated protein antibodies isolated from human serum and synovial fluid

scientific article published in June 2010

HLA and RA revisited: citrullinated food for the SE hypothesis, the DR6 effect, and NIMA.

scientific article

HLA-B60 and the HLA-B27/HLA-B60 genotype are not risk factors for acute anterior uveitis.

scientific article

Haematogenous infection of a prosthetic joint

scientific article published in January 2013

Health care usage in Dutch systemic lupus erythematosus patients ⬇️

scientific article published on July 18, 2011

Health-care utilization in Dutch systemic sclerosis patients

scientific article published on 28 August 2013

Health-related quality of life and functional ability in patients with early arthritis during remission steered treatment: results of the IMPROVED study

scientific article published on 31 October 2013

High innate production of interleukin-10 and tumor necrosis factor-alpha contributes to susceptibility for non-paraneoplastic Lambert-Eaton myasthenic syndrome

scientific article published on 01 July 2003

High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis

scientific article

How to avoid phenotypic misclassification in using joint destruction as an outcome measure for rheumatoid arthritis?

scientific article published on 04 March 2010

How to prevent, minimize, or extinguish nocebo effects in pain: a narrative review on mechanisms, predictors, and interventions

scientific article published on 01 May 2019

Human mast cells costimulate T cells through a CD28-independent interaction

scientific article published on 10 February 2016

IL-10 and toll-like receptor-4 polymorphisms and the in vivo and ex vivo response to endotoxin

article

IL-17-producing CD4+ T cells are increased in early, active axial spondyloarthritis including patients without imaging abnormalities

scientific article published on 6 October 2014

Identification and characterisation of citrullinated antigen-specific B cells in peripheral blood of patients with rheumatoid arthritis.

scientific article

Identification of PLOD2 as telopeptide lysyl hydroxylase, an important enzyme in fibrosis

scientific article

Identification of a genetic variant for joint damage progression in autoantibody-positive rheumatoid arthritis.

scientific article published on 16 August 2013

Identification of a novel non-coding mutation in C1qB in a Dutch child with C1q deficiency associated with recurrent infections.

scientific article published on 18 October 2014

Identification of citrullinated vimentin peptides as T cell epitopes in HLAâ DR4â positive patients with rheumatoid arthritis

scientific article published on 01 January 2010

Identification of regulators of the myofibroblast phenotype of primary dermal fibroblasts from early diffuse systemic sclerosis patients

scientific article published on 14 March 2019

IgE and IL-33-mediated triggering of human basophils inhibits TLR4-induced monocyte activation.

scientific article

Illness perceptions, risk perceptions and worries in patients with early systemic sclerosis: A focus group study

scientific article published on 26 January 2020

Immature Dendritic Cells Suppress Collagen-Induced Arthritis by In Vivo Expansion of CD49b+ Regulatory T Cells

scientific article published on 01 September 2006

Immunoglobulin 1 (IgG1) Fc-glycosylation profiling of anti-citrullinated peptide antibodies from human serum.

scientific article published on 20 November 2008

Immunohistochemical analysis as a means to predict responsiveness to rituximab treatment

article

Immunomodulatory Dendritic Cells Inhibit Th1 Responses and Arthritis via Different Mechanisms

article

Impact of pulmonary fibrosis and elevated pulmonary pressures on right ventricular function in patients with systemic sclerosis

scientific article published on 15 October 2015

Impaired innate immunity predicts frailty in old age. The Leiden 85-plus study

scientific article published on 01 September 2004

Improved early identification of arthritis: evaluating the efficacy of Early Arthritis Recognition Clinics

scientific article published on 5 September 2012

Improved treatment strategies reduce the increased mortality risk in early RA patients

scientific article published on 09 August 2010

In RA, becoming seronegative over the first year of treatment does not translate to better chances of drug-free remission

scientific article published on 25 July 2018

In erosive hand osteoarthritis more inflammatory signs on ultrasound are found than in the rest of hand osteoarthritis

scientific article published on 20 July 2012

In rheumatoid arthritis, changes in autoantibody levels reflect intensity of immunosuppression, not subsequent treatment response

scholarly article by Emma C de Moel et al published 18 January 2019 in Arthritis Research and Therapy

In the clinic. Rheumatoid arthritis

scientific article published on July 2010

In vitro matrigel fibroblast invasion assay

scientific article published in January 2007

Incidence and risk factors for adalimumab and infliximab anti-drug antibodies in rheumatoid arthritis: A European retrospective multicohort analysis

scientific article published on 12 October 2018

Increased formation of pyridinoline cross-links due to higher telopeptide lysyl hydroxylase levels is a general fibrotic phenomenon

scientific article

Increased incidence of pregnancy complications in women who later develop scleroderma: a case control study

scientific article published on 4 November 2011

Induction of long-term B-cell depletion in refractory rheumatoid arthritis patients preferentially affects autoreactive more than protective humoral immunity

scientific article

Induction of sustained remission in early inflammatory arthritis with the combination of infliximab plus methotrexate: the DINORA trial

Inflammation and ectopic lymphoid structures in rheumatoid arthritis synovial tissues dissected by genomics technology: identification of the interleukin-7 signaling pathway in tissues with lymphoid neogenesis

scientific article published on 01 August 2007

Inflammation underlying cardiovascular mortality is a late consequence of evolutionary programming

scientific article

Integration of sequence data from a Consanguineous family with genetic data from an outbred population identifies PLB1 as a candidate rheumatoid arthritis risk gene

scientific article

Interleukin 10 secretion in relation to human IL-10 locus haplotypes ⬇️

scientific article published on August 4, 1998

Interleukin-10 microsatellite polymorphisms and IL-10 locus alleles in rheumatoid arthritis susceptibility ⬇️

scientific article published on October 17, 1998

Interleukin-10 promoter haplotypes are differently distributed in the Brazilian versus the Dutch population

scientific article

Invasiveness of fibroblast-like synoviocytes is an individual patient characteristic associated with the rate of joint destruction in patients with rheumatoid arthritis

scientific article published on 01 July 2005

Is HLA-B27 increased in patients diagnosed with undifferentiated arthritis? Results from the Leiden early arthritis cohort.

scientific article published on 15 August 2014

Is optimising gout treatment the key to closing the mortality gap in gout patients?

scientific article published on 25 May 2017

Is the Site of Back Pain Related to the Location of Magnetic Resonance Imaging Lesions in Patients With Chronic Back Pain? Results From the Spondyloarthritis Caught Early Cohort

scientific article published on 2 August 2016

Is the tuberculin skin test an accurate method of detecting tuberculosis in patients with rheumatoid arthritis?

scientific article published on 01 April 2006

Large-joint damage in patients with early rheumatoid arthritis and its association with treatment strategy and damage of the small joints

scientific article published in September 2012

Left ventricular dysfunction assessed by speckle-tracking strain analysis in patients with systemic sclerosis: relationship to functional capacity and ventricular arrhythmias

scientific article published in December 2011

Long-Term Outcomes of Patients With Recent-Onset Rheumatoid Arthritis After 10 Years of Tight Controlled Treatment: A Randomized Trial

scientific article

Long-term impact of delay in assessment of patients with early arthritis

scientific article published on 01 December 2010

Long-term mortality in patients with ST-segment elevation myocardial infarction is associated with anti-citrullinated protein antibodies

scientific article published on 25 April 2017

Loss of imprinting of IGF2 characterises high IGF2 mRNA-expressing type of fibroblast-like synoviocytes in rheumatoid arthritis

scientific article published on 24 June 2009

Loss of metacarpal bone density predicts RA development in recent-onset arthritis

scientific article published on 18 January 2012

Low-avidity anticitrullinated protein antibodies (ACPA) are associated with a higher rate of joint destruction in rheumatoid arthritis.

scientific article published on 5 March 2013

Lung function is associated with minimal EQ-5D changes over time in patients with systemic sclerosis

scientific article published on 24 January 2020

MR signal intensity: staying on the bright side in MR image interpretation.

scientific article

MRI of hand and foot joints of patients with anticitrullinated peptide antibody positive arthralgia without clinical arthritis

scientific article published on 19 January 2013

Magnetic resonance imaging of the sacroiliac joints in the early detection of spondyloarthritis: no added value of gadolinium compared with short tau inversion recovery sequence

scientific article published on 16 February 2013

Magnetic resonance imaging-detected inflammation is associated with functional disability in early arthritis-results of a cross-sectional study

scientific article

Marked differences in fine specificity and isotype usage of the anti-citrullinated protein antibody in health and disease

article

Marked variability in clinical presentation and outcome of patients with C1q immunodeficiency

scientific article

Mast cell depletion in the preclinical phase of collagen-induced arthritis reduces clinical outcome by lowering the inflammatory cytokine profile

scientific article published on 13 June 2016

Mast cells are the main interleukin 17-positive cells in anticitrullinated protein antibody-positive and -negative rheumatoid arthritis and osteoarthritis synovium

scientific article published on 20 September 2011

Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci

scientific journal article

Metabolic stress–induced inflammation plays a major role in the development of osteoarthritis in mice ⬇️

scientific article published on October 27, 2011

Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis.

scientific article published on 11 August 2017

Multiple sclerosis and type 1 diabetes in Sardinia

scientific article published in October 2002

Murine Fc receptors for IgG are redundant in facilitating presentation of immune complex derived antigen to CD8+ T cells in vivo

scientific article published on 28 February 2006

N-Linked Glycans in the Variable Domain of IgG Anti-Citrullinated Protein Antibodies Predict the Development of Rheumatoid Arthritis

scientific article published on 02 September 2019

N-of-1 trial of low-dose methotrexate and/or prednisolone in lieu of anti-CCP, MRI, or ultrasound, as first option in suspected rheumatoid arthritis?

scientific article published on 01 February 2007

Neuropsychiatric manifestations in patients with systemic lupus erythematosus: epidemiology and radiology pointing to an immune-mediated cause

scientific article

Neuropsychiatric systemic lupus erythematosus: Lessons learned from magnetic resonance imaging ⬇️

scientific article published on 01 March 2011

Neutralization of IL-4 reverses the nonresponsiveness of CD4+ T cells to regulatory T-cell induction in non-responder mouse strains.

scientific article published on 25 September 2010

New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis

scientific article

Off-label use of rituximab for systemic lupus erythematosus in Europe

scientific article

Older age is associated with more MRI-detected inflammation in hand and foot joints

scientific article published on 29 September 2016

On-drug and drug-free remission by baseline symptom duration: abatacept with methotrexate in patients with early rheumatoid arthritis

scholarly article by Vivian P Bykerk et al published 20 October 2018 in Rheumatology International

One year in review 2020: novelties in the treatment of rheumatoid arthritis

scientific article published on 26 March 2020

Optimization of short-term transgene expression by sodium butyrate and ubiquitous chromatin opening elements (UCOEs).

scientific article published in August 2007

Osteophytes and joint space narrowing are independently associated with pain in finger joints in hand osteoarthritis

scientific article published on 8 July 2011

P2-006　　profiles of receptors for specialized lipid mediators on synoviocyte from osteoarthritis

scientific article published on 01 January 2014

PADI4 polymorphism predisposes male smokers to rheumatoid arthritis

scientific article published on 09 November 2010

Pain in hand osteoarthritis is associated with inflammation: the value of ultrasound

scientific article published on 14 May 2010

Pathogenic relevance of anti–citrullinated vimentin antibodies: Comment on the article by Montes et al ⬇️

scientific article published on February 1, 2013

Patients with chronic back pain of short duration from the SPACE cohort: which MRI structural lesions in the sacroiliac joints and inflammatory and structural lesions in the spine are most specific for axial spondyloarthritis?

scientific article

Patients with early arthritis consume less alcohol than controls, regardless of the type of arthritis.

scientific article published on 20 June 2013

Percentage of patients with spondyloarthritis in patients referred because of chronic back pain and performance of classification criteria: experience from the Spondyloarthritis Caught Early (SPACE) cohort

scientific article

Percentage of patients with spondyloarthritis in patients referred because of chronic back pain and performance of classification criteria: experience from the Spondyloarthritis Caught Early (SPACE) cohort

scientific article published on 20 May 2015

Performance of classification criteria for peripheral spondyloarthritis and psoriatic arthritis in the Leiden Early Arthritis cohort

scientific article published on 13 April 2012

Performance of the proposed ACR-EULAR classification criteria for systemic lupus erythematosus (SLE) in a cohort of patients with SLE with neuropsychiatric symptoms.

scientific article published on 5 June 2019

Personalized medicine: predicting responses to therapy in patients with RA.

scientific article published on 08 April 2013

Pharmacological conditioning in the treatment of recent-onset rheumatoid arthritis: a randomized controlled trial study protocol

scientific article published on 06 January 2020

Platelets and autoimmunity.

scientific article published on 26 April 2013

Potential role of pharmacogenetics in anti-TNF treatment of rheumatoid arthritis and Crohn's disease

scientific article published on 4 December 2006

Predicting arthritis outcomes--what can be learned from the Leiden Early Arthritis Clinic?

scientific article published on 16 July 2010

Predicting cardiopulmonary involvement in patients with systemic sclerosis: complementary value of nailfold videocapillaroscopy patterns and disease-specific autoantibodies

scientific article published on 10 December 2016

Predictive factors of radiological progression after 2 years of remission-steered treatment in early arthritis patients: a post hoc analysis of the IMPROVED study

scientific article published on 15 February 2016

Presence of IgM anti-topoisomerase I antibodies is associated with disease progression in anti-topoisomerase I IgG positive systemic sclerosis

scientific article published on 17 June 2020

Prevalence of and predictive factors for sustained disease-modifying antirheumatic drug-free remission in rheumatoid arthritis: Results from two large early arthritis cohorts

scientific article published on 01 August 2009

Prevalence of vertebral fractures in a disease activity steered cohort of patients with early active rheumatoid arthritis ⬇️

scientific article published on July 23, 2012

Preventing progression from arthralgia to arthritis: targeting the right patients.

scientific article published on 9 November 2017

Prevention of autoimmune rheumatic disease: state of the art and future perspectives

scientific article published on December 2010

Production of IL-1beta and IL-1Ra as risk factors for susceptibility and progression of relapse-onset multiple sclerosis

scientific article published on 01 May 2002

Profiling the secretion of soluble mediators by end stage osteoarthritis synovial tissue explants reveals a reduced responsiveness to an inflammatory trigger

scientific article

Prognostic properties of anti-topoisomerase antibodies in patients identified by the ACR/EULAR 2013 systemic sclerosis criteria

scientific article published on 01 April 2019

Progression of Left Ventricular Myocardial Dysfunction in Systemic Sclerosis: A Speckle-tracking Strain Echocardiography Study

scientific article published on 01 March 2019

Progression of structural damage is not related to rituximab serum levels in rheumatoid arthritis patients

scientific article published on 24 April 2013

Prospective study of clinical phenotypes in neuropsychiatric systemic lupus erythematosus; multidisciplinary approach to diagnosis and therapy

scientific article published on 15 September 2012

Protection against anti-citrullinated protein antibody-positive rheumatoid arthritis is predominantly associated with HLA-DRB1*1301: a meta-analysis of HLA-DRB1 associations with anti-citrullinated protein antibody-positive and anti-citrullinated pr

scientific article

Protective effect of HLA-DRB1*13 alleles during specific phases in the development of ACPA-positive RA.

scientific article published on 29 December 2015

Protective effect of noninherited maternal HLA-DR antigens on rheumatoid arthritis development

scholarly article

Protein array autoantibody profiles to determine diagnostic markers for neuropsychiatric systemic lupus erythematosus

scientific article published on 27 April 2017

Pulmonary fibrosis in a patient with rheumatoid arthritis treated with adalimumab

scientific article published on 01 February 2006

Quality indicators in rheumatoid arthritis: results from the METEOR database

scientific article

Quality indicators in rheumatology: valid for whom?

scientific article published on 01 December 2009

Quantitative heritability of anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis.

scientific article published on April 2009

Rapid radiological progression in the first year of early rheumatoid arthritis is predictive of disability and joint damage progression during 8 years of follow-up ⬇️

scientific article published on April 24, 2012

Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry

scientific article

Reappraisal of the diagnostic and prognostic value of morning stiffness in arthralgia and early arthritis: results from the Groningen EARC, Leiden EARC, ESPOIR, Leiden EAC and REACH.

scientific article published on 23 April 2015

Reasons for medical help-seeking behaviour of patients with recent-onset arthralgia

scientific article published on 6 September 2012

Recent advances in the management of rheumatoid arthritis

scientific article published on 21 December 2010

Recognition of citrullinated and carbamylated proteins by human antibodies: specificity, cross-reactivity and the 'AMC-Senshu' method

scientific article

Recommendations for publication of genetic association studies in Arthritis & Rheumatism

scientific article published on 01 October 2011

Redefining the HLA and RA association: to be or not to be anti-CCP positive.

scientific article

Refining the complex rheumatoid arthritis phenotype based on specificity of the HLA-DRB1 shared epitope for antibodies to citrullinated proteins

scientific article

Relationship between genetic variants in the adenosine pathway and outcome of methotrexate treatment in patients with recent-onset rheumatoid arthritis

scientific article published on 01 September 2006

Relationship of multi-biomarker disease activity score and other risk factors with radiographic progression in an observational study of patients with rheumatoid arthritis

scientific article

Remission induction therapy with methotrexate and prednisone in patients with early rheumatoid and undifferentiated arthritis (the IMPROVED study)

scientific article published on 08 March 2012

Repair of joint erosions in rheumatoid arthritis: prevalence and patient characteristics in a large inception cohort.

scientific article

Residual inflammation after rituximab treatment is associated with sustained synovial plasma cell infiltration and enhanced B cell repopulation

scientific article published on 22 July 2008

Response to 'Feasibility of tailored treatment based on risk stratification in patients with early rheumatoid arthritis'--authors' reply

scientific article published on 2 July 2015

Retraction Note: Mast cells are the main interleukin 17-positive cells in anticitrullinated protein antibody-positive and -negative rheumatoid arthritis and osteoarthritis synovium

scholarly article by Jolien Suurmond et al published 9 December 2015 in Arthritis Research and Therapy

Rheumatoid arthritis

scientific article published in The Lancet

Rheumatoid arthritis is a heterogeneous disease: evidence for differences in the activation of the STAT-1 pathway between rheumatoid tissues

scientific article

Rheumatoid arthritis patients with continued low disease activity have similar outcomes over 10 years, regardless of initial therapy

scientific article published in October 2017

Rheumatoid arthritis risk allele PTPRC is also associated with response to anti-tumor necrosis factor alpha therapy

scientific article published on July 2010

Rheumatoid arthritis: 2014 treat-to-target RA recommendations--strategy is key.

scientific article published on 21 July 2015

Rheumatoid arthritis: Seronegative and seropositive RA: alike but different?

scientific article

Rheumatoid arthritis: can we achieve true drug-free remission in patients with RA?

scientific article published on 01 February 2010

Rheumatoid arthritis: the goal rather than the health-care provider is key.

scientific article published in February 2006

Risk factors for reported influenza and influenza-like symptoms in patients with rheumatoid arthritis ⬇️

scientific article published on July 20, 2012

Risk of alanine transferase (ALT) elevation in patients with rheumatoid arthritis treated with methotrexate in a DAS-steered strategy ⬇️

scientific article published on December 9, 2012

Risk of rheumatoid arthritis development in patients with unclassified arthritis according to the 2010 ACR/EULAR criteria for rheumatoid arthritis

scientific article published on 7 March 2013

Rituximab in early systemic sclerosis

scientific article published on 28 July 2017

Rituximab in relapsing Graves' disease, a phase II study.

scientific article published on 15 July 2008

Role of Tumor Necrosis Factor–α and Interleukin‐10 Promoter Gene Polymorphisms in Leprosy

article

Sarilumab Plus Methotrexate in Patients With Active Rheumatoid Arthritis and Inadequate Response to Methotrexate: Results of a Phase III Study

scientific article

Sarilumab plus methotrexate improves patient-reported outcomes in patients with active rheumatoid arthritis and inadequate responses to methotrexate: results of a phase III trial.

scientific article published on 06 September 2016

Sarilumab, a fully human monoclonal antibody against IL-6Rα in patients with rheumatoid arthritis and an inadequate response to methotrexate: efficacy and safety results from the randomised SARIL-RA-MOBILITY Part A trial

scientific article

Seasonal variation of primary neuropsychiatric systemic lupus erythematosus

scientific article published on 01 September 2006

Selective involvement of the amygdala in systemic lupus erythematosus

scientific article (publication date: December 2006)

Serum pyridinoline levels and prediction of severity of joint destruction in rheumatoid arthritis

scientific article published on 01 June 2013

Sex hormones and sex hormone-targeting therapies in systemic sclerosis: A systematic literature review

scientific article published on 20 July 2019

Shared symptoms in rheumatic diseases: a blessing or a curse?

scientific article published on 01 September 2009

Shrinking Lung Syndrome: Diagnostic and Therapeutic Challenges in 3 Patients With Systemic Lupus Erythematosus

scientific article published on 02 September 2019

Similar short-term clinical response to high-dose versus low-dose methotrexate in monotherapy and combination therapy in patients with rheumatoid arthritis

scientific article published on 22 November 2017

Single nucleotide polymorphisms (SNPs) at -238 and -308 positions in the TNFalpha promoter: clinical and bacteriological evaluation in leprosy

scientific article

Smoking and systemic sclerosis: influence on microangiopathy and expression of anti-topoisomerase I antibodies in a monocentric cohort

scientific article published on 25 March 2020

Smoking is associated with the concurrent presence of multiple autoantibodies in rheumatoid arthritis rather than with anti-citrullinated protein antibodies per se: a multicenter cohort study.

scientific article published on December 2016

Soluble FcgammaRIIIa as a marker for rheumatoid arthritis: the use of genetics in selected populations to study pathogenetic pathways.

scientific article

Structural Analysis of Variable Domain Glycosylation of Anti-Citrullinated Protein Antibodies in Rheumatoid Arthritis Reveals the Presence of Highly Sialylated Glycans

scientific article

Studies on ageing and the severity of radiographic joint damage in rheumatoid arthritis

scientific article

Subclinical inflammation on MRI of hand and foot of anticitrullinated peptide antibody-negative arthralgia patients at risk for rheumatoid arthritis

scientific article

Substitution of the quantitative serological component in the 2010 criteria for RA with qualitative presence of three autoantibodies yields similar performance: response to the article by Regueiro et al

scientific article published on 15 April 2020

Suppression of bone turnover by B-cell depletion in patients with rheumatoid arthritis ⬇️

scientific article published on 06 April 2011

Suppressor activity among CD4+,CD25++ T cells is discriminated by membrane-bound tumor necrosis factor α

article by Jun Wang et al published 2008 in Arthritis and Rheumatism

Survival, comorbidities and joint damage 11 years after the COBRA combination therapy trial in early rheumatoid arthritis

scientific article published on 17 May 2009

Sustained drug-free remission in rheumatoid arthritis after DAS-driven or non-DAS-driven therapy: a comparison of two cohort studies

scientific article published on 15 February 2012

Sustained improvements in MRI outcomes with abatacept following the withdrawal of all treatments in patients with early, progressive rheumatoid arthritis ⬇️

scientific article published on 10 February 2016

Sustained remission in rheumatoid arthritis: latest evidence and clinical considerations

scientific article published on 2 August 2017

Synovial fluid mononuclear cells provide an environment for long-term survival of antibody-secreting cells and promote the spontaneous production of anti-citrullinated protein antibodies

scientific article published on 11 April 2016

Systemic lupus erythematosus: diagnostic application of magnetization transfer ratio histograms in patients with neuropsychiatric symptoms--initial results

scientific article published in March 2002

TAC-TIC use of tacrolimus-based regimens in lupus nephritis

scientific article published on 29 December 2016

TRAF1/C5 polymorphism is not associated with increased mortality in rheumatoid arthritis: two large longitudinal studies

scientific article

The 2010 American College of Rheumatology/European League Against Rheumatism classification criteria for rheumatoid arthritis: Phase 2 methodological report

scientific article

The ACPA isotype profile reflects long-term radiographic progression in rheumatoid arthritis

scientific article

The ACPA recognition profile and subgrouping of ACPA-positive RA patients

scientific article published on 13 October 2011

The B cell response to citrullinated antigens in the development of rheumatoid arthritis.

scientific article published on 8 February 2018

The BeSt story: on strategy trials in rheumatoid arthritis

scientific article published on May 2009

The Course of Bone Marrow Edema in Early Undifferentiated Arthritis and Rheumatoid Arthritis: A Longitudinal Magnetic Resonance Imaging Study at Bone Level

scientific article published on 17 December 2015

The HLA–DRB1 shared epitope alleles are primarily a risk factor for anti–cyclic citrullinated peptide antibodies and are not an independent risk factor for development of rheumatoid arthritis

article

The HLA–DRB1 shared epitope alleles differ in the interaction with smoking and predisposition to antibodies to cyclic citrullinated peptide

scientific article published on 01 February 2007

The R-H polymorphism of FCgamma receptor IIa as a risk factor for systemic lupus erythematosus is independent of single-nucleotide polymorphisms in the interleukin-10 gene promoter

scientific article published on 01 April 2002

The TRAF1-C5 region on chromosome 9q33 is associated with multiple autoimmune diseases.

scientific article published on 10 May 2009

The additive value of magnetic resonance imaging for bone edema in predicting rheumatoid arthritis development in early undifferentiated arthritis: Comment on the article by Duer‐Jensen et al ⬇️

scientific article published on 01 January 2012

The anti-carbamylated protein antibody response is of overall low avidity despite extensive isotype switching

scientific article published on 01 September 2018

The battle between anti-cyclic citrullinated peptide and rheumatoid factor tests--a winner at last?

scientific article

The concentration of anticitrullinated protein antibodies in serum and synovial fluid in relation to total immunoglobulin concentrations

scientific article published on 13 March 2013

The contribution of sex and auto-antibodies to microangiopathy assessed by nailfold videocapillaroscopy in systemic sclerosis: a systematic review of the literature

scientific article published on 21 January 2020

The devil in the details: the emerging role of anticitrulline autoimmunity in rheumatoid arthritis

scientific article

The effect of corticosteroid medication on quantitative MR parameters of the brain

scientific article published in November 2005

The effect of pentoxifylline on human neutrophil migration: A possible role for cyclic nucleotides ⬇️

scientific article published on August 15, 1997

The fine specificity of IgM anti-citrullinated protein antibodies (ACPA) is different from that of IgG ACPA.

scientific article published on 30 November 2011

The genetics of rheumatoid arthritis: risk and protection in different stages of the evolution of RA.

scientific article

The impact of four dynamic, goal-steered treatment strategies on the 5-year outcomes of rheumatoid arthritis patients in the BeSt study

scientific article published on 17 March 2011

The increased ability to present citrullinated peptides is not unique to HLA-SE molecules: arginine-to-citrulline conversion also enhances peptide affinity for HLA-DQ molecules

scientific article published on 3 November 2016

The influence of ACPA status and characteristics on the course of RA.

scientific article published on 31 January 2012

The interaction between HLA shared epitope alleles and smoking and its contribution to autoimmunity against several citrullinated antigens

scientific article published on July 2011

The isotype and IgG subclass distribution of anti-carbamylated protein antibodies in rheumatoid arthritis patients

scientific article published on 15 August 2017

The joint-gut axis in inflammatory bowel diseases

scientific article published on 30 November 2009

The pathogenic potential of autoreactive antibodies in rheumatoid arthritis.

scientific article published on 25 April 2014

The prevalence of ACPA is lower in rheumatoid arthritis patients with an older age of onset but the composition of the ACPA response appears identical.

scientific article

The production and secretion of complement component C1q by human mast cells

scientific article

The role of anticitrullinated protein antibodies in the early stages of rheumatoid arthritis

scientific article published on 4 March 2016

The role of interleukin 10 promoter polymorphisms in the susceptibility of distal interphalangeal osteoarthritis

scientific article published in August 2005

The specificity of anti-carbamylated protein antibodies for rheumatoid arthritis in a setting of early arthritis.

scientific article published on 24 November 2015

The type of collagen cross-link determines the reversibility of experimental skin fibrosis

scientific article published on 5 March 2005

The window of opportunity in ACPA-positive rheumatoid arthritis is not explained by ACPA characteristics

scientific article published on 10 April 2011

Therapeutic and diagnostic outcomes of a standardised, comprehensive care pathway for patients with systemic sclerosis

scientific article published on 15 March 2016

Thumb base involvement in symptomatic hand osteoarthritis is associated with more pain and functional disability

scientific article published on 02 February 2010

To what extent do autoantibodies help to identify high-risk patients in systemic sclerosis?

scientific article published on 18 July 2018

Towards gene therapy in prosthesis loosening: efficient killing of interface cells by gene-directed enzyme prodrug therapy with nitroreductase and the prodrug CB1954.

scientific article published in November 2005

Towards personalized treatment: predictors of short-term HAQ response in recent-onset active rheumatoid arthritis are different from predictors of rapid radiological progression ⬇️

scientific article published on November 21, 2011

Tract-based spatial statistics on diffusion tensor imaging in systemic lupus erythematosus reveals localized involvement of white matter tracts

scientific article published on December 2010

Transcription of the IL10 gene reveals allele-specific regulation at the mRNA level

scientific article published on 15 June 2004

Transient expression of FOXP3 in human activated nonregulatory CD4+ T cells

scientific article published on 01 January 2007

Transition of healthy to diseased synovial tissue in rheumatoid arthritis is associated with gain of mesenchymal/fibrotic characteristics

scientific article published on January 2006

Treat-to-Target Strategies in Rheumatoid Arthritis

scientific article published on 01 July 2019

Treatment strategies in recent onset rheumatoid arthritis

scientific article published on May 2011

Triple Positivity for Anti-Citrullinated Protein Autoantibodies, Rheumatoid Factor, and Anti-Carbamylated Protein Antibodies Conferring High Specificity for Rheumatoid Arthritis

scientific article published on 16 September 2018

Tumor necrosis factor-alpha +489G/A gene polymorphism is associated with chronic obstructive pulmonary disease

scientific article

Tumor necrosis factor-alpha genetic predisposing factors can influence clinical severity in nephropathia epidemica

scientific article

Tweaking microtubules to treat scleroderma

scientific article

Twenty-eight-week results from the REALISTIC phase IIIb randomized trial: efficacy, safety and predictability of response to certolizumab pegol in a diverse rheumatoid arthritis population ⬇️

scientific article

Two years of sarilumab in patients with rheumatoid arthritis and an inadequate response to MTX: safety, efficacy and radiographic outcomes

scholarly article by Mark C Genovese et al published 1 August 2018 in Rheumatology

Two-year results of disease activity score (DAS)-remission-steered treatment strategies aiming at drug-free remission in early arthritis patients (the IMPROVED-study)

scientific article

Understanding the genetic contribution to rheumatoid arthritis

scientific article

Using a reference when defining an abnormal MRI reduces false-positive MRI results-a longitudinal study in two cohorts at risk for rheumatoid arthritis

scientific article published in October 2017

Using predicted disease outcome to provide differentiated treatment of early rheumatoid arthritis.

scientific article published on 15 July 2006

Validation of a prediction rule for disease outcome in patients with recent-onset undifferentiated arthritis: Moving toward individualized treatment decision-making

scientific article published on 01 August 2008

Validity and responsiveness of the Michigan Hand Questionnaire in patients with systemic sclerosis

scientific article

Validity of the disease activity score in undifferentiated arthritis

scientific article

Value of anti-modified citrullinated vimentin and third-generation anti-cyclic citrullinated peptide compared with second-generation anti-cyclic citrullinated peptide and rheumatoid factor in predicting disease outcome in undifferentiated arthritis a

scientific article published on 01 August 2009

Value of multidisciplinary reassessment in attribution of neuropsychiatric events to systemic lupus erythematosus: prospective data from the Leiden NPSLE cohort.

scientific article

Variants of gene for microsomal prostaglandin E2 synthase show association with disease and severe inflammation in rheumatoid arthritis

scientific article

Variation in radiologic joint destruction in rheumatoid arthritis differs between monozygotic and dizygotic twins and pairs of unrelated patients

scientific article published on 01 June 2006

Vascular compromise of a finger due to tenosynovitis

scientific article published on 01 February 2008

When rheumatologists report that they agree with a guideline, does this mean that they practise the guideline in clinical practice? Results of the International Recommendation Implementation Study (IRIS).

scientific article published on 28 April 2016

Which elements of the criteria for RA are stable over time?

scientific article published on 10 August 2010

Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases

scientific article

[Progress due to genetic research on rheumatoid arthritis: hype or hope?]

scientific article published on 01 January 2009

‘Insights in the relationship of joint space narrowing versus erosive joint damage and physical functioning of patients with RA‘ ⬇️

scientific article published on June 30, 2012

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