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List of works by James A. Nicoll

A novel method to visualise the three-dimensional organisation of the human cerebral cortical vasculature.

scientific article published on 9 March 2018

A quartet of Down's syndrome, Alzheimer's disease, cerebral amyloid angiopathy, and cerebral haemorrhage: interacting genetic risk factors ⬇️

scientific article published on September 1, 1998

APOE gene polymorphism as a risk factor for cerebral amyloid angiopathy-related hemorrhage

scientific article published on 01 July 2001

Adult-Onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia Caused by a Novel R782G Mutation in CSF1R.

scientific article

Alterations in cerebrospinal fluid apolipoprotein E and amyloid beta-protein after traumatic brain injury.

scientific article

Analysis of Mutations in AARS2 in a Series of CSF1R-Negative Patients With Adult-Onset Leukoencephalopathy With Axonal Spheroids and Pigmented Glia.

scientific article published on 17 October 2016

Animal models of cerebral amyloid angiopathy.

scientific article

Apolipoprotein E ε4 allele is associated with deposition of amyloid β-protein following head injury ⬇️

scientific article published on February 1, 1995

Association between APOE genotype, neuropathology and dementia in the older population of England and Wales.

scientific article published in April 2011

Association of APOE e4 and cerebrovascular pathology in traumatic brain injury

scientific article

Aβ immunotherapy for Alzheimer's disease: effects on apoE and cerebral vasculopathy.

scientific article published on 7 September 2014

Aβ43 in human Alzheimer's disease: effects of active Aβ42 immunization

scientific article published on 02 September 2019

Cerebral amyloid angiopathy plays a direct role in the pathogenesis of Alzheimer's disease. Pro-CAA position statement.

scientific article published on May 2004

Cerebral amyloid angiopathy: Pathogenesis and effects on the ageing and Alzheimer brain ⬇️

scientific article published on September 1, 2003

Cerebral amyloid angiopathy: both viper and maggot in the brain.

scientific article published in September 2005

Cerebrovascular disease and the pathophysiology of Alzheimer's disease. Implications for therapy.

scientific article

Cerebrovascular disease is a major factor in the failure of elimination of Abeta from the aging human brain: implications for therapy of Alzheimer's disease.

scientific article published in November 2002

Choroid plexus in the central canal of the spinal cord causing recurrent syringomyelia

scientific article

Comparison of modified Bielschowsky silver impregnation and anti‐ubiquitin immunostaining of cortical and nigral Lewy bodies ⬇️

scientific article published on December 1, 1992

Consequence of Abeta immunization on the vasculature of human Alzheimer's disease brain.

scientific article

Corticosteroid-responsive focal granulomatous herpes simplex type-1 encephalitis in adults.

scientific article published on 2 February 2017

Cytokine gene polymorphisms and outcome after traumatic brain injury

scientific article published on 24 August 2013

Decompressive craniectomy for acute disseminated encephalomyelitis.

scientific article published on December 2010

Deposition of amyloid β in the walls of human leptomeningeal arteries in relation to perivascular drainage pathways in cerebral amyloid angiopathy

scientific article published on 28 August 2015

Disruption of arterial perivascular drainage of amyloid-β from the brains of mice expressing the human APOE ε4 allele

scientific article (publication date: 2012)

EXOSC3 mutations in pontocerebellar hypoplasia type 1: novel mutations and genotype-phenotype correlations

scientific article published on 13 February 2014

Effect of apolipoprotein E genotype on hematoma volume after trauma

scientific article published on 01 January 2002

Effect of apolipoprotein E genotype on in-hospital mortality following intracerebral haemorrhage

scientific article published on 01 February 2003

Genetic variation in the 5-HT2A receptor and altered neocortical [3H] ketanserin binding in Alzheimer's disease.

scientific article

High frequency of apolipoprotein E ϵ2 allele is specific for patients with cerebral amyloid angiopathy-related haemorrhage ⬇️

scientific article published on May 8, 1998

Immune complex formation impairs the elimination of solutes from the brain: implications for immunotherapy in Alzheimer's disease.

scientific article published on 9 August 2013

Immunotherapy for Alzheimer's Disease and Other Dementias

scientific article published on 01 January 2006

Immunotherapy for Alzheimer's disease and other dementias.

scientific article published in December 2005

Innate immunity in Alzheimer's disease: the relevance of animal models?

scientific article

Investigating interventions in Alzheimer's disease with computer simulation models

scientific article

Involvement of apolipoprotein E in glioblastoma: immunohistochemistry and clinical outcome.

scientific article

Long-term intracerebral inflammatory response after traumatic brain injury

scientific article published on 01 December 2004

Metaflammasome components in the human brain: a role in dementia with Alzheimer's pathology?

scientific article

Microglial alterations in human Alzheimer's disease following Aβ42 immunization.

scientific article published in August 2011

Microglial immunophenotype in dementia with Alzheimer's pathology.

scientific article published on 02 June 2016

Microglial motility in Alzheimer's disease and after Aβ42 immunotherapy: a human post-mortem study

scientific article published on 08 November 2019

Microvasculature changes and cerebral amyloid angiopathy in Alzheimer's disease and their potential impact on therapy.

scientific article published on 22 February 2009

Mitochondrial DNA and traumatic brain injury

scientific article

Molecular Mechanisms of Microglial Motility: Changes in Ageing and Alzheimer's Disease

scientific article published on 25 June 2019

Neuroinflammation in ageing and in neurodegenerative disease

scientific article published on 01 February 2013

Neuropathology after active Abeta42 immunotherapy: implications for Alzheimer's disease pathogenesis.

scientific article published on 15 July 2010

New neuropathological findings in Unverricht-Lundborg disease: neuronal intranuclear and cytoplasmic inclusions

scientific article published on 19 August 2010

No evidence for the presence of apolipoprotein epsilon4, interleukin-lalpha allele 2 and interleukin-1beta allele 2 cause an increase in programmed cell death following traumatic brain injury in humans.

scientific article published in November 2006

Novel antibodies detect additional α-synuclein pathology in synucleinopathies: potential development for immunotherapy

scientific article published on 30 November 2020

Novel association between microglia and stem cells in human gliomas: A contributor to tumour proliferation?

scientific article published on 14 January 2015

Nucleus basalis of Meynert pathology in the human brain after fatal head injury.

scientific article

PCR-mediated search for herpes simplex virus DNA in sections of brain from patients with multiple sclerosis and other neurological disorders

scientific article published on December 1, 1992

PKR modulates abnormal brain signaling in experimental obesity.

scientific article

PO81A LACK OF CONSENT TO DONATE BRAIN TUMOUR TISSUE FOR RESEARCH HAMPERS PROGRESS.

scientific article

Pathophysiology of dementias and implications for therapy.

scientific article published on July 2005

Perivascular drainage of solutes is impaired in the ageing mouse brain and in the presence of cerebral amyloid angiopathy

scientific article published on 23 January 2011

Persistent neuropathological effects 14 years following amyloid-β immunization in Alzheimer's disease

scientific article published on 01 July 2019

Population studies of sporadic cerebral amyloid angiopathy and dementia: a systematic review.

scientific article published on 13 January 2009

Prenatal high-fat diet alters the cerebrovasculature and clearance of β-amyloid in adult offspring

scientific article published on 7 January 2015

Pyroglutamate and Isoaspartate modified Amyloid-Beta in ageing and Alzheimer's disease

scientific article published on 3 January 2018

Quantification of molecular interactions between ApoE, amyloid-beta (Aβ) and laminin: Relevance to accumulation of Aβ in Alzheimer's disease

scientific article

Rapid neuroinflammatory changes in human acute intracerebral hemorrhage

scientific article published on 13 July 2019

Rat astrocytic tumour cells are associated with an anti-inflammatory microglial phenotype in an organotypic model.

scientific article

Recurrent hemorrhage in cerebral amyloid angiopathy.

scientific article

Review: activation patterns of microglia and their identification in the human brain.

scientific article published on February 2013

Splenic haematoma after spontaneous rupture of the spleen ⬇️

scientific article published on 01 July 1968

Surgery for cerebral amyloid angiopathy-related hemorrhage

scientific article published on 01 June 1999

Systemic infection modifies the neuroinflammatory response in late stage Alzheimer's disease

article

Systems proteomic analysis reveals that clusterin and tissue inhibitor of metalloproteinases 3 increase in leptomeningeal arteries affected by cerebral amyloid angiopathy

scientific article published on 20 August 2016

TREM2 expression in the human brain: a marker of monocyte recruitment?

scientific article published on 7 October 2017

Tau immunohistochemistry in acute brain injury ⬇️

scientific article published on October 1, 2003

The Apolipoprotein E ε4 Allele and Outcome in Cerebrovascular Disease ⬇️

scientific article published on September 1, 1998

The Edinburgh CT and genetic diagnostic criteria for lobar intracerebral haemorrhage associated with cerebral amyloid angiopathy: model development and diagnostic test accuracy study

scientific article published on 10 January 2018

The association between APOE ε4, age and outcome after head injury: a prospective cohort study

scientific article published on 20 July 2005

The biochemical aftermath of anti-amyloid immunotherapy ⬇️

scientific article published on October 7, 2010

The neuroinflammatory response in humans after traumatic brain injury.

scientific article published on October 2013

Use of the polymerase chain reaction to detect herpes simplex virus DNA in paraffin sections of human brain at necropsy ⬇️

scientific article published on February 1, 1991

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