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List of works by Casper G. Schalkwijk

(Pre)diabetes, glycemia, and daily glucose variability are associated with retinal nerve fiber layer thickness in The Maastricht Study

scientific article published in 2022

40 EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004 ⬇️

article

A Common Gene Variant in Glucokinase Regulatory Protein Interacts With Glucose Metabolism on Diabetic Dyslipidemia: the Combined CODAM and Hoorn Studies

scientific article published on October 2016

A control systems approach to quantify wall shear stress normalization by flow-mediated dilation in the brachial artery

scientific article

A healthy diet is associated with less endothelial dysfunction and less low-grade inflammation over a 7-year period in adults at risk of cardiovascular disease

scientific article published on 31 December 2014

ACE-inhibition modulates some endothelial functions in healthy subjects and in normotensive type 1 diabetic patients

scientific article published on 01 October 2000

Abdominal fat mass is associated with adaptive immune activation: the CODAM Study

scientific article published on 20 January 2011

Activated complement factor 3 is associated with liver fat and liver enzymes: the CODAM study

scientific article

Activating transcription factor 6 polymorphisms and haplotypes are associated with impaired glucose homeostasis and type 2 diabetes in Dutch Caucasians

scientific article

Adapted dietary inflammatory index and its association with a summary score for low-grade inflammation and markers of glucose metabolism: the Cohort study on Diabetes and Atherosclerosis Maastricht (CODAM) and the Hoorn study.

scientific article

Adiponectin is inversely associated with renal function in type 1 diabetic patients

scientific article

Advanced Glycation End Product (AGE) Accumulation in the Skin is Associated with Depression: The Maastricht Study

scientific article

Advanced glycation end products are associated with pulse pressure in type 1 diabetes: the EURODIAB Prospective Complications Study

scientific article published on 25 April 2005

Advanced glycation end products in human cancer tissues: detection of Nepsilon-(carboxymethyl)lysine and argpyrimidine

scientific article published in June 2005

Advanced glycation end-product peptides are associated with impaired renal function, but not with biochemical markers of endothelial dysfunction and inflammation, in non-diabetic individuals

scientific article

Advanced glycation end-products, anti-hypertensive treatment and diastolic function in patients with hypertension and diastolic dysfunction

scientific article

Advanced glycation endproducts and its receptor for advanced glycation endproducts in obesity

scientific article published on February 2013

Age-related accrual of methylomic variability is linked to fundamental ageing mechanisms

scientific article published on 22 September 2016

Aggressive antihypertensive therapy based on hydrochlorothiazide, candesartan or lisinopril as initial choice in hypertensive type II diabetic individuals: effects on albumin excretion, endothelial function and inflammation in a double-blind, random

scientific article published in June 2005

Alcohol and red wine consumption, but not fruit, vegetables, fish or dairy products, are associated with less endothelial dysfunction and less low-grade inflammation: the Hoorn Study

scientific article published on 27 March 2017

Amadori albumin in type 1 diabetic patients: correlation with markers of endothelial function, association with diabetic nephropathy, and localization in retinal capillaries

scientific article published on 01 December 1999

Amadori-albumin correlates with microvascular complications and precedes nephropathy in type 1 diabetic patients

scientific article published in July 2002

An integrated set-up for ex vivo characterisation of biaxial murine artery biomechanics under pulsatile conditions

scientific article published on 29 January 2021

Analysis of advanced glycation endproducts in selected food items by ultra-performance liquid chromatography tandem mass spectrometry: Presentation of a dietary AGE database

scientific article published on 18 June 2015

Angiotensin II blockade is associated with decreased plasma leukocyte adhesion molecule levels in diabetic nephropathy

scientific article published on 01 July 2000

Association between mannose-binding lectin and vascular complications in type 1 diabetes

scientific article published in June 2004

Association of Type D personality with increased vulnerability to depression: Is there a role for inflammation or endothelial dysfunction? - The Maastricht Study

scientific article published on 25 September 2015

Association of polymorphism in the receptor for advanced glycation end products (RAGE) gene with circulating RAGE levels

scientific article published on 4 November 2009

Associations between advanced glycation endproducts and matrix metalloproteinases and its inhibitor in individuals with type 1 diabetes

scientific article published on 3 January 2018

Associations between the ankle-brachial index and cardiovascular and all-cause mortality are similar in individuals without and with type 2 diabetes: nineteen-year follow-up of a population-based cohort study

scientific article

BclI Glucocorticoid Receptor Polymorphism Is Associated With Greater Body Fatness: The Hoorn and CODAM Studies

BclI Glucocorticoid Receptor Polymorphism in Relation to Arterial Stiffening and Cardiac Structure and Function: The Hoorn and CODAM Studies

scientific article published on 17 January 2017

BclI glucocorticoid receptor polymorphism in relation to cardiovascular variables: the Hoorn and CODAM studies

scientific article published on 2 July 2015

Beneficial effects of aminoguanidine on peritoneal microcirculation and tissue remodelling in a rat model of PD.

scientific article

Blood lipids influence DNA methylation in circulating cells

scientific article published on 27 June 2016

Blood metabolomic measures associate with present and future glycemic control in type 2 diabetes

C-reactive protein in type 1 diabetes and its relationship to coronary artery calcification

scientific article published in October 2002

CD11c<sup>-</sup>MHC2<sup>low</sup> Macrophages Are a New Inflammatory and Dynamic Subset in Murine Adipose Tissue

scientific article published on 01 April 2020

Capillary Rarefaction Associates with Albuminuria: The Maastricht Study

scientific article

Cardiovascular and Patient Phenotype of Extended Haemodialysis: A Critical Analysis of Studying a Unique Patient Population

scientific article published on 16 February 2018

Characterization of Immune Cells in Human Adipose Tissue by Using Flow Cytometry.

scientific article published on 6 March 2018

Circulating Polyunsaturated Fatty Acids as Biomarkers for Dietary Intake across Subgroups: The CODAM and Hoorn Studies

scientific article published on 25 January 2018

Circulating classical monocytes are associated with CD11c+ macrophages in human visceral adipose tissue

scientific article published on 15 February 2017

Circulating matrix metalloproteinases are associated with arterial stiffness in patients with type 1 diabetes: pooled analysis of three cohort studies

scientific article published on 25 October 2017

Citrate anticoagulation abolishes degranulation of polymorphonuclear cells and platelets and reduces oxidative stress during haemodialysis

scientific article

Clinical and prognostic value of advanced glycation end-products in chronic heart failure

scientific article published on 5 November 2007

Comment on: Selvin et al. sRAGE and risk of diabetes, cardiovascular disease, and death. Diabetes 2013;62:2116-2121.

scientific article published on October 2013

Complement activation products C5a and sC5b-9 are associated with low-grade inflammation and endothelial dysfunction, but not with atherosclerosis in a cross-sectional analysis: The CODAM study

article

Complement c3 is inversely associated with habitual intake of provitamin A but not with dietary fat, fatty acids, or vitamin E in middle-aged to older white adults and positively associated with intake of retinol in middle-aged to older white women

scientific article published on 30 October 2013

Complement factor 3 is associated with insulin resistance and with incident type 2 diabetes over a 7-year follow-up period: the CODAM Study

scientific article published on 23 April 2014

Contribution of lactate buffer, glucose and glucose degradation products to peritoneal injury in vivo ⬇️

scientific article published on December 1, 2003

Current therapeutic interventions in the glycation pathway: evidence from clinical studies

scientific article published on 25 January 2013

Delayed Intervention With Pyridoxamine Improves Metabolic Function and Prevents Adipose Tissue Inflammation and Insulin Resistance in High-Fat Diet-Induced Obese Mice

scientific article published on 30 December 2015

Depression and markers of inflammation as predictors of all-cause mortality in heart failure

scientific article published on 17 March 2016

Diabetes mellitus worsens diastolic left ventricular dysfunction in aortic stenosis through altered myocardial structure and cardiomyocyte stiffness.

scientific article

Diastolic Stiffness of the Failing Diabetic Heart

scientific article published on 10 December 2007

Diet-induced weight loss improves not only cardiometabolic risk markers but also markers of vascular function: a randomized controlled trial in abdominally obese men.

scientific article published on 23 November 2016

Dietary Advanced Glycation End Products Consumption as a Direct Modulator of Insulin Sensitivity in Overweight Humans: A Study Protocol for a Double-Blind, Randomized, Two Period Cross-Over Trial.

scientific article published on 29 July 2015

Dietary factors and low-grade inflammation in relation to overweight and obesity

scientific article published on December 2011

Dietary intake of advanced glycation endproducts is associated with higher levels of advanced glycation endproducts in plasma and urine: The CODAM study

scientific article published on 23 March 2017

Discriminatory ability of simple OGTT-based beta cell function indices for prediction of prediabetes and type 2 diabetes: the CODAM study

scientific article

Disease variants alter transcription factor levels and methylation of their binding sites

scientific article published on 5 December 2016

Distinct Longitudinal Associations of MBL, MASP-1, MASP-2, MASP-3, and MAp44 With Endothelial Dysfunction and Intima-Media Thickness: The Cohort on Diabetes and Atherosclerosis Maastricht (CODAM) Study

scientific article published on 7 April 2016

Distinct accumulation patterns of soluble forms of E-selectin, VCAM-1 and ICAM-1 upon infusion of TNFalpha in tumor patients

scientific article

Distinct associations of HbA1c and the urinary excretion of pentosidine, an advanced glycosylation end-product, with markers of endothelial function in insulin-dependent diabetes mellitus

scientific article published on 01 July 1998

Dose-finding study of the multitargeted tyrosine kinase inhibitor SU6668 in patients with advanced malignancies

scientific article

Dysfunctional adipose tissue and low-grade inflammation in the management of the metabolic syndrome: current practices and future advances

scientific article

Early- and advanced non-enzymatic glycation in diabetic vascular complications: the search for therapeutics ⬇️

scientific article published on October 20, 2010

Effect of atorvastatin on C-reactive protein and benefits for cardiovascular disease in patients with type 2 diabetes: analyses from the Collaborative Atorvastatin Diabetes Trial

scientific article published on 22 April 2015

Effect of benfotiamine on advanced glycation endproducts and markers of endothelial dysfunction and inflammation in diabetic nephropathy

scientific article

Effects of rosuvastatin and atorvastatin on glycaemic control in Type 2 diabetes---the CORALL study

scientific article published on May 2012

Effects of short-term treatment with metformin on markers of endothelial function and inflammatory activity in type 2 diabetes mellitus: a randomized, placebo-controlled trial

scientific article published in January 2005

Effects of sodium and potassium supplementation on endothelial function: a fully controlled dietary intervention study

scientific article published on 7 September 2015

Effects of transdermal and oral oestrogen replacement therapy on C-reactive protein levels in postmenopausal women: a randomised, placebo-controlled trial

scientific article published in October 2002

Effects of tumour necrosis factor-alpha in the human forearm: blood flow and endothelin-1 release

scientific article published in October 2002

Endoplasmic reticulum stress-induced apoptosis in the development of diabetes: is there a role for adipose tissue and liver?

scientific article published on December 2009

Endothelial dysfunction and inflammation predict development of diabetic nephropathy in the Irbesartan in Patients with Type 2 Diabetes and Microalbuminuria (IRMA 2) study

scientific article published in January 2008

Endothelial dysfunction and low-grade inflammation are associated with greater arterial stiffness over a 6-year period

scientific article published on 22 August 2011

Endothelial dysfunction in (pre)diabetes: characteristics, causative mechanisms and pathogenic role in type 2 diabetes

scientific article published on March 2013

Endothelial dysfunction is associated with a greater depressive symptom score in a general elderly population: the Hoorn Study

scientific article published on 13 August 2013

Energy restriction and Roux-en-Y gastric bypass reduce postprandial α-dicarbonyl stress in obese women with type 2 diabetes

scientific article published on 16 June 2016

Erratum to: Plasma levels of matrix metalloproteinase-2, -3, -10, and tissue inhibitor of metalloproteinase-1 are associated with vascular complications in patients with type 1 diabetes: the EURODIAB Prospective Complications Study

scientific article published on 28 September 2015

Erythropoietin and vascular endothelial growth factor as risk markers for severe hypoglycaemia in type 1 diabetes

scientific article published on 21 June 2010

Extracellular overhydration linked with endothelial dysfunction in the context of inflammation in haemodialysis dependent chronic kidney disease

scientific article published on 22 August 2017

Fasting and postprandial glycoxidative and lipoxidative stress are increased in women with type 2 diabetes

scientific article published on 27 April 2007

Fish Consumption in Healthy Adults Is Associated with Decreased Circulating Biomarkers of Endothelial Dysfunction and Inflammation during a 6-Year Follow-Up

scholarly article by Bas C. T. van Bussel et al published 13 July 2011 in Journal of Nutrition

Glyoxalase 1 overexpression does not affect atherosclerotic lesion size and severity in ApoE-/- mice with or without diabetes

scientific article published on 18 August 2014

Glyoxalase-1 overexpression partially prevents diabetes-induced impaired arteriogenesis in a rat hindlimb ligation model

scientific article

Glyoxalase-1 overexpression reduces endothelial dysfunction and attenuates early renal impairment in a rat model of diabetes

scientific article published on 26 October 2013

Heat-shock protein 27 is a major methylglyoxal-modified protein in endothelial cells

scientific article published on 3 February 2006

Hepatic Fat Content and Liver Enzymes Are Associated with Circulating Free and Protein-Bound Advanced Glycation End Products, Which Are Associated with Low-Grade Inflammation: The CODAM Study

scientific article published on 14 May 2019

High-Density Lipoproteins Exert Pro-inflammatory Effects on Macrophages via Passive Cholesterol Depletion and PKC-NF-κB/STAT1-IRF1 Signaling

scientific article

Higher Plasma Methylglyoxal Levels Are Associated With Incident Cardiovascular Disease and Mortality in Individuals With Type 2 Diabetes

scientific article published on 21 May 2018

Higher Plasma Methylglyoxal Levels Are Associated With Incident Cardiovascular Disease in Individuals With Type 1 Diabetes: A 12-Year Follow-up Study

scientific article published on 06 June 2017

Higher dietary salt intake is associated with microalbuminuria, but not with retinopathy in individuals with type 1 diabetes: the EURODIAB Prospective Complications Study

scientific article

Higher levels of complement C3a (activated C3) are cross-sectionally associated with higher carotid media thickness and lower ankle-arm blood pressure index: The CODAM study

scholarly article by Elisabeth Hertle et al published November 2012 in Immunobiology

Higher plasma high-mobility group box 1 levels are associated with incident cardiovascular disease and all-cause mortality in type 1 diabetes: a 12 year follow-up study

scientific article

Higher plasma levels of advanced glycation end products are associated with incident cardiovascular disease and all-cause mortality in type 1 diabetes: a 12-year follow-up study ⬇️

scientific article

Higher plasma soluble Receptor for Advanced Glycation End Products (sRAGE) levels are associated with incident cardiovascular disease and all-cause mortality in type 1 diabetes: a 12-year follow-up study ⬇️

scientific article

Homocysteine-lowering treatment with folic acid plus vitamin B6 lowers urinary albumin excretion but not plasma markers of endothelial function or C-reactive protein: further analysis of secondary end-points of a randomized clinical trial

scientific article published in March 2003

Human plasma complement C3 is independently associated with coronary heart disease, but only in heavy smokers (the CODAM study)

Humoral markers of inflammation and endothelial dysfunction in relation to adiposity and in vivo insulin action in Pima Indians

scientific article published in March 2002

Hyperglycaemia-induced impairment of endothelium-dependent vasorelaxation in rat mesenteric arteries is mediated by intracellular methylglyoxal levels in a pathway dependent on oxidative stress

scientific article

Hyperglycemia Is the Main Mediator of Prediabetes- and Type 2 Diabetes-Associated Impairment of Microvascular Function: The Maastricht Study.

scientific article published on 16 June 2017

Hypertension is a conditional factor for the development of cardiac hypertrophy in type 2 diabetic mice

scientific article published on 9 January 2014

Identification of context-dependent expression quantitative trait loci in whole blood

scientific article published on 5 December 2016

Immunopathological changes in a uraemic rat model for peritoneal dialysis

scientific article

Impact of metformin versus repaglinide on non-glycaemic cardiovascular risk markers related to inflammation and endothelial dysfunction in non-obese patients with type 2 diabetes

scientific article published on May 2008

Impaired HDL cholesterol efflux in metabolic syndrome is unrelated to glucose tolerance status: the CODAM study

scientific article published on 08 June 2016

Impaired renal function is associated with markers of endothelial dysfunction and increased inflammatory activity

scientific article published in May 2003

Improved biocompatibility of bicarbonate/lactate-buffered PDF is not related to pH.

scientific article published in November 2005

Improved glycemic control induced by both metformin and repaglinide is associated with a reduction in blood levels of 3-deoxyglucosone in nonobese patients with type 2 diabetes

scientific article published on 4 January 2011

In the Elderly, Endothelial Dysfunction and Low-grade Inflammation do not Play A Prominent Role in Local Arterial Stiffening – The Hoorn Study -

In vivo effects of sex steroids on lymphocyte responsiveness and immunoglobulin levels in humans

scientific article

Increased Nepsilon-(carboxymethyl)-lysine levels in cerebral blood vessels of diabetic patients and in a (streptozotocin-treated) rat model of diabetes mellitus

scientific article published on May 2008

Increased accumulation of the glycoxidation product Nepsilon-(carboxymethyl)lysine in hearts of diabetic patients: generation and characterisation of a monoclonal anti-CML antibody

scientific article

Increased levels of N(epsilon)-(carboxymethyl)lysine and N(epsilon)-(carboxyethyl)lysine in type 1 diabetic patients with impaired renal function: correlation with markers of endothelial dysfunction

scientific article published in March 2004

Independent tissue contributors to obesity-associated insulin resistance

scientific article

Inflammatory and Angiogenic Factors Linked to Longitudinal Microvascular Changes in Hemodialysis Patients Irrespective of Treatment Dose Intensity

scientific article published on 16 November 2017

Inflammatory markers, adiponectin, and risk of type 2 diabetes in the Pima Indian.

scientific article published in June 2003

Influence of icodextrin on plasma and dialysate levels of N(epsilon)-(carboxymethyl)lysine and N(epsilon)-(carboxyethyl)lysine

scientific article published on November 2005

Irbesartan treatment does not influence plasma levels of the advanced glycation end products N(epsilon)(1-carboxymethyl)lysine and N(epsilon)(1-carboxyethyl)lysine in patients with type 2 diabetes and microalbuminuria. A randomized controlled trial

scientific article published on 8 March 2011

Irbesartan treatment does not influence plasma levels of the dicarbonyls methylglyoxal, glyoxal and 3-deoxyglucosone in participants with type 2 diabetes and microalbuminuria: an IRMA2 sub-study

scientific article published on 22 September 2020

Irbesartan treatment reduces biomarkers of inflammatory activity in patients with type 2 diabetes and microalbuminuria: an IRMA 2 substudy

scientific article published in December 2006

Iron metabolism is associated with adipocyte insulin resistance and plasma adiponectin: the Cohort on Diabetes and Atherosclerosis Maastricht (CODAM) study

scientific article published on 6 September 2012

Iron metabolism is prospectively associated with insulin resistance and glucose intolerance over a 7-year follow-up period: the CODAM study

scientific article published in October 2014

Irreversible renal damage after transient renin-angiotensin system stimulation: involvement of an AT1-receptor mediated immune response

scientific article

L(+) and D(-) lactate are increased in plasma and urine samples of type 2 diabetes as measured by a simultaneous quantification of L(+) and D(-) lactate by reversed-phase liquid chromatography tandem mass spectrometry

scientific article published on 8 March 2012

Levels of NT-proBNP, markers of low-grade inflammation, and endothelial dysfunction during spironolactone treatment in patients with diabetic kidney disease

scientific article published on 29 October 2012

Long-term effects of metformin on endothelial function in type 2 diabetes: a randomized controlled trial

scientific article

Long-term exposure to new peritoneal dialysis solutions: Effects on the peritoneal membrane

scientific article

Longitudinal associations of the alternative and terminal pathways of complement activation with adiposity: The CODAM study

scientific article

Loss of DPP4 activity is related to a prothrombogenic status of endothelial cells: implications for the coronary microvasculature of myocardial infarction patients ⬇️

scientific article published on December 14, 2011

Low 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3 levels are independently associated with macroalbuminuria, but not with retinopathy and macrovascular disease in type 1 diabetes: the EURODIAB prospective complications study

scientific article published on 30 May 2015

Low-grade inflammation and endothelial dysfunction explain the association between retinopathy and left ventricular ejection fraction in men: an 8-year follow-up of the Hoorn Study

scientific article published on 19 June 2014

Low-grade inflammation and insulin resistance independently explain substantial parts of the association between body fat and serum C3: The CODAM study

scholarly article by Nick Wlazlo et al published December 2012 in Metabolism

Low-grade inflammation can partly explain the association between the metabolic syndrome and either coronary artery disease or severity of peripheral arterial disease: the CODAM study

scientific article published on 9 April 2009

Low-grade inflammation, but not endothelial dysfunction, is associated with greater carotid stiffness in the elderly: the Hoorn Study

scientific article published in April 2012

Markers of Endothelial Dysfunction and Inflammation in Type 1 Diabetic Patients With or Without Diabetic Nephropathy Followed for 10 Years: Association with mortality and decline of glomerular filtration rate

scientific article published on 10 March 2008

Markers of inflammation and endothelial dysfunction are associated with incident cardiovascular disease, all-cause mortality, and progression of coronary calcification in type 2 diabetic patients with microalbuminuria

scientific article

Markers of low-grade inflammation and endothelial dysfunction are related to reduced information processing speed and executive functioning in an older population - the Hoorn Study

scientific article published on 22 November 2013

Measurement of Nepsilon-(carboxymethyl)lysine and Nepsilon-(carboxyethyl)lysine in human plasma protein by stable-isotope-dilution tandem mass spectrometry

scientific article

Measurement of pentosidine in human plasma protein by a single-column high-performance liquid chromatography method with fluorescence detection

scientific article published on 23 January 2009

Methylglyoxal and glyoxalase I in atherosclerosis

scientific article published on April 2014

Methylglyoxal and methylglyoxal-arginine adducts do not directly inhibit endothelial nitric oxide synthase

scientific article

Methylglyoxal stress, the glyoxalase system, and diabetic chronic kidney disease

scientific article published on 01 January 2019

Mevastatin increases eNO synthase expression and inhibits lipid peroxidation in human endothelial cells

scientific article

MicroRNA-126 and micro-/macrovascular complications of type 1 diabetes in the EURODIAB Prospective Complications Study

scientific article published on October 2016

Mild oxidative damage in the diabetic rat heart is attenuated by glyoxalase-1 overexpression

scientific article published on 29 July 2013

Modulation of insulin action by advanced glycation endproducts: a new player in the field

scientific article published on 15 September 2008

Modulation of plasma endothelin levels by the menstrual cycle

scientific article published on 01 May 2000

Multiple inflammatory biomarker detection in a prospective cohort study: a cross-validation between well-established single-biomarker techniques and an electrochemiluminescense-based multi-array platform

scientific article

N epsilon-(carboxymethyl)lysine during the early development of hypertension

scientific article

N(omega)-(carboxymethyl)lysine depositions in human aortic heart valves: similarities with atherosclerotic blood vessels

scientific article

NH2-terminal probrain natriuretic peptide is associated with diabetes complications in the EURODIAB Prospective Complications Study: the role of tumor necrosis factor-α.

scientific article

Nepsilon-(carboxymethyl)lysine, Nepsilon-(carboxyethyl)lysine and vascular cell adhesion molecule-1 (VCAM-1) in relation to peritoneal glucose prescription and residual renal function; a study in peritoneal dialysis patients

scientific article published in April 2004

Nitric oxide dysregulation in patients with heart failure: the association of depressive symptoms with L-arginine, asymmetric dimethylarginine, symmetric dimethylarginine, and isoprostane

scientific article published in April 2015

Obesity-associated low-grade inflammation in type 2 diabetes mellitus: causes and consequences

scientific article published on May 1, 2013

Optimal antiproteinuric dose of aliskiren in type 2 diabetes mellitus: a randomised crossover trial

scientific article published on 18 May 2010

Overexpression of glyoxalase-I reduces hyperglycemia-induced levels of advanced glycation end products and oxidative stress in diabetic rats

scientific article

Plasma Methylglyoxal Levels Are Associated With Amputations and Mortality in Severe Limb Ischemia Patients With and Without Diabetes

scientific article published on 03 November 2020

Plasma asymmetric dimethylarginine (ADMA) concentration is independently associated with carotid intima-media thickness and plasma soluble vascular cell adhesion molecule-1 (sVCAM-1) concentration in patients with mild-to-moderate renal failure

scientific article

Plasma concentration of C-reactive protein is increased in type I diabetic patients without clinical macroangiopathy and correlates with markers of endothelial dysfunction: evidence for chronic inflammation

scientific article published on 01 March 1999

Plasma homocysteine is weakly correlated with plasma endothelin and von Willebrand factor but not with endothelium-dependent vasodilatation in healthy postmenopausal women.

scientific article published in August 1999

Plasma levels of AGE peptides in type 1 diabetic patients are associated with serum creatinine and not with albumin excretion rate: possible role of AGE peptide-associated endothelial dysfunction

scientific article published in June 2005

Plasma levels of advanced glycation end products are associated with haemolysis‐related organ complications in sickle cell patients ⬇️

scientific article published on July 30, 2010

Plasma levels of advanced glycation endproducts Nε-(carboxymethyl)lysine, Nε-(carboxyethyl)lysine, and pentosidine are not independently associated with cardiovascular disease in individuals with or without type 2 diabetes: the Hoorn and CODAM studi

scientific article published on 18 June 2013

Plasma levels of advanced glycation endproducts are associated with type 1 diabetes and coronary artery calcification

scientific article

Plasma levels of matrix metalloproteinase-2, -3, -10, and tissue inhibitor of metalloproteinase-1 are associated with vascular complications in patients with type 1 diabetes: the EURODIAB Prospective Complications Study

scientific article

Plasma matrix metalloproteinases are associated with incident cardiovascular disease and all-cause mortality in patients with type 1 diabetes: a 12-year follow-up study

scientific article published on 26 April 2017

Platelet and leukocyte activation, atherosclerosis and inflammation in European and South Asian men

scientific article published on October 2007

Polymorphisms in glyoxalase 1 gene are not associated with vascular complications: the Hoorn and CoDAM studies

scientific article published in July 2009

Post-Glucose Load Plasma α-Dicarbonyl Concentrations Are Increased in Individuals With Impaired Glucose Metabolism and Type 2 Diabetes: The CODAM Study

scientific article published on 20 February 2015

Prevention of age-induced N(ε)-(carboxymethyl)lysine accumulation in the microvasculature

scientific article published on 4 February 2016

Protein-Bound Plasma Nε-(Carboxymethyl)lysine Is Inversely Associated With Central Obesity and Inflammation and Significantly Explain a Part of the Central Obesity-Related Increase in Inflammation: The Hoorn and CODAM Studies

scientific article

Protein-bound uraemic toxins, dicarbonyl stress and advanced glycation end products in conventional and extended haemodialysis and haemodiafiltration

scientific article published on 9 April 2015

Quantification of glyoxal, methylglyoxal and 3-deoxyglucosone in blood and plasma by ultra performance liquid chromatography tandem mass spectrometry: evaluation of blood specimen ⬇️

scientific article published on 01 January 2014

Raloxifene, conjugated oestrogen and endothelial function in postmenopausal women

scientific article

Receptor for advanced glycation end product polymorphisms and type 2 diabetes: the CODAM study

scientific article

Reducing sitting time versus adding exercise: differential effects on biomarkers of endothelial dysfunction and metabolic risk.

scientific article

Renal effects of aliskiren compared with and in combination with irbesartan in patients with type 2 diabetes, hypertension, and albuminuria

scientific article published on 08 July 2009

Role of methylglyoxal adducts in the development of vascular complications in diabetes mellitus

scientific article published on December 2003

Serum advanced glycation endproducts are associated with left ventricular dysfunction in normal glucose metabolism but not in type 2 diabetes: The Hoorn Study

scientific article published on 2 May 2016

Serum heat shock protein 27 and diabetes complications in the EURODIAB prospective complications study: a novel circulating marker for diabetic neuropathy

scientific article published on 4 April 2008

Short-term hormone replacement therapy: reduced plasma levels of soluble adhesion molecules

scientific article published on 01 November 1999

Single exposure of mesothelial cells to glucose degradation products (GDPs) yields early advanced glycation end-products (AGEs) and a proinflammatory response.

scientific article published in May 2003

Skin Autofluorescence and Pentosidine Are Associated With Aortic Stiffening: The Maastricht Study

scientific article published on 22 August 2016

Skin-autofluorescence, a measure of tissue advanced glycation end-products (AGEs), is related to diastolic function in dialysis patients

scientific article published on 27 May 2008

Soluble C5b-9, a marker for terminal complement activation, is not associated with markers of atherosclerosis or prevalent cardiovascular disease: The CODAM study

Soluble vascular cell adhesion molecule-1 and soluble E-selectin are associated with micro- and macrovascular complications in Type 1 diabetic patients

scientific article published in May 2006

Structural and enzymological properties of cellular phospholipases A2

scientific journal article

Subcutaneous Adipose Tissue and Systemic Inflammation Are Associated With Peripheral but Not Hepatic Insulin Resistance in Humans

scientific article published on 06 September 2019

Supplementation of the Pure Flavonoids Epicatechin and Quercetin Affects Some Biomarkers of Endothelial Dysfunction and Inflammation in (Pre)Hypertensive Adults: A Randomized Double-Blind, Placebo-Controlled, Crossover Trial

scientific article published on 13 May 2015

Surface Area of Detachment, Proliferative Vitreoretinopathy, and Pulse Pressure, but not AGEs, are Associated With Retinal Redetachment

scientific article published in December 2016

Targeting hyperglycaemia with either metformin or repaglinide in non-obese patients with type 2 diabetes: results from a randomized crossover trial

scientific article published in May 2007

The ATF6-Met[67]Val substitution is associated with increased plasma cholesterol levels

scientific article published on 10 August 2009

The Course of Skin and Serum Biomarkers of Advanced Glycation Endproducts and Its Association with Oxidative Stress, Inflammation, Disease Severity, and Mortality during ICU Admission in Critically Ill Patients: Results from a Prospective Pilot Stud

scientific article

The Influence of Bicarbonate/Lactate-Buffered PD Fluids on Nε-(Carboxyethyl)Lysine and Nε-(Carboxymethyl)Lysine in Peritoneal Effluent ⬇️

scientific article published on July 29, 2010

The Role of Hyperglycemia, Insulin Resistance, and Blood Pressure in Diabetes-Associated Differences in Cognitive Performance-The Maastricht Study

scientific article published on 25 August 2017

The alternative complement pathway is longitudinally associated with adverse cardiovascular outcomes. The CODAM study

scientific article published on 8 October 2015

The association between the -374T/A polymorphism of the receptor for advanced glycation endproducts gene and blood pressure and arterial stiffness is modified by glucose metabolism status: the Hoorn and CoDAM studies

scientific article published in February 2010

The association between the metabolic syndrome and alanine amino transferase is mediated by insulin resistance via related metabolic intermediates (the Cohort on Diabetes and Atherosclerosis Maastricht [CODAM] study)

scholarly article by Marjon Jacobs et al published July 2011 in Metabolism

The association between the metabolic syndrome and peripheral, but not coronary, artery disease is partly mediated by endothelial dysfunction: the CODAM study

scholarly article by Marjon Jacobs et al published 8 October 2010 in European Journal of Clinical Investigation

The cross-sectional association between insulin resistance and circulating complement C3 is partly explained by plasma alanine aminotransferase, independent of central obesity and general inflammation (the CODAM study)

scholarly article by Marleen M. J. van Greevenbroek et al published 26 November 2010 in European Journal of Clinical Investigation

The cross-sectional association between uric acid and atherosclerosis and the role of low-grade inflammation: the CODAM study

The effect of atorvastatin therapy on tumour necrosis factor-α and vascular adhesion molecules in patients with type 2 diabetes mellitus with no prior history of coronary heart disease

scientific article published in November 2011

The effect of calcium dobesilate on vascular endothelial function, blood pressure, and markers of oxidation in obese male smokers: a placebo-controlled randomised clinical trial.

scientific article published on September 2003

The endothelial function biomarker soluble E-selectin is associated with nonalcoholic fatty liver disease

scientific article published on 20 January 2020

The hypoxia-sensor carbonic anhydrase IX affects macrophage metabolism, but is not a suitable biomarker for human cardiovascular disease

scientific article published on 11 January 2021

The methylglyoxal-derived AGE tetrahydropyrimidine is increased in plasma of individuals with type 1 diabetes mellitus and in atherosclerotic lesions and is associated with sVCAM-1.

scientific article published on 26 April 2013

The role of methylglyoxal and the glyoxalase system in diabetes and other age-related diseases

scientific article published on June 2015

The systolic-diastolic difference in carotid stiffness is increased in type 2 diabetes: The Maastricht Study

scientific article published on May 2017

Time course of the antiproteinuric and antihypertensive effects of direct renin inhibition in type 2 diabetes

scientific article published on 12 March 2008

Unhealthy dietary patterns associated with inflammation and endothelial dysfunction in type 1 diabetes: the EURODIAB study.

scientific article published on 12 July 2012

Up-regulation of the complement system in subcutaneous adipocytes from nonobese, hypertriglyceridemic subjects is associated with adipocyte insulin resistance

scientific article

Upstream transcription factor 1 (USF1) in risk of type 2 diabetes: Association study in 2000 Dutch Caucasians

Vascular complications in diabetes mellitus: the role of endothelial dysfunction

scientific article

Vascular risk factors and markers of endothelial function as determinants of inflammatory markers in type 1 diabetes: the EURODIAB Prospective Complications Study

scientific article published in July 2003

Vitamin E inhibits lipid peroxidation-induced adhesion molecule expression in endothelial cells and decreases soluble cell adhesion molecules in healthy subjects

scientific article

Vitreous advanced glycation endproducts and α-dicarbonyls in retinal detachment patients with type 2 diabetes mellitus and non-diabetic controls

scientific article

Weight loss moderately affects the mixed meal challenge response of the plasma metabolome and transcriptome of peripheral blood mononuclear cells in abdominally obese subjects

scientific article published on 5 March 2018

“NEPP” Peritoneal Dialysis Regimen has Beneficial Effects on Plasma Cel and 3-DG, but not Pentosidine, CML, and MGO ⬇️

scientific article published on May 31, 2011

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