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List of works by Jason Sheltzer

A CRISPR Competition Assay to Identify Cancer Genetic Dependencies

scientific article published in 2020

A scientific partnership

scientific article published in July 2014

A transcriptional and metabolic signature of primary aneuploidy is present in chromosomally unstable cancer cells and informs clinical prognosis

scientific article published on 16 September 2013

An elevated rate of whole-genome duplications in cancers from Black patients

scientific article published on 19 September 2024

Aneuploidy drives genomic instability in yeast

scientific article published on August 2011

Aneuploidy increases resistance to chemotherapeutics by antagonizing cell division

scientific article published on 17 November 2020

Angelika Amon (1967-2020)

scientific article published on 01 December 2020

CRISPR/Cas9 mutagenesis invalidates a putative cancer dependency targeted in on-going clinical trials

scientific article published on 24 March 2017

Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity

scientific article published on 05 August 2020

Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity

scientific article

Cigarette smoke exposure and inflammatory signaling increase the expression of the SARS-CoV-2 receptor ACE2 in the respiratory tract

scientific article published on 16 May 2020

Cigarette smoke exposure and inflammatory signaling increase the expression of the SARS-CoV-2 receptor ACE2 in the respiratory tract

scientific article published on 31 March 2020

Discovering and validating cancer genetic dependencies: approaches and pitfalls

scientific article published on 19 June 2020

Elite male faculty in the life sciences employ fewer women

scientific article

Field-theoretic density estimation for biological sequence space with applications to 5' splice site diversity and aneuploidy in cancer

Gender disparities among independent fellows in biomedical research

article

Generating Single Cell-Derived Knockout Clones in Mammalian Cells with CRISPR/Cas9

scientific article published on 01 September 2019

Genome-wide identification and analysis of prognostic features in human cancers

scientific article published on 01 March 2022

Increasing gender diversity in the STEM research workforce

scientific article published on 01 November 2019

MELK expression correlates with tumor mitotic activity but is not required for cancer growth.

scientific article published on 8 February 2018

Micronuclei-based model system reveals functional consequences of chromothripsis in human cells

scientific article published on 28 November 2019

Mitotic entry in the presence of DNA damage is a widespread property of aneuploidy in yeast

scientific article

Off-target toxicity is a common mechanism of action of cancer drugs undergoing clinical trials

scientific article published on 01 September 2019

Oncogene-like addiction to aneuploidy in human cancers

scientific article published on 06 July 2023

Single-Chromosomal Gains Can Function as Metastasis Suppressors and Promoters in Colon Cancer

scientific article published on 01 February 2020

Single-chromosome Gains Commonly Function as Tumor Suppressors

scientific article published on 29 December 2016

Systematic identification of mutations and copy number alterations associated with cancer patient prognosis

scientific article published on 11 December 2018

The aneuploidy paradox: costs and benefits of an incorrect karyotype

scientific article published on 26 August 2011

The class V myosin Myo2p is required for Fus2p transport and actin polarization during the yeast mating response

scientific article

The next Nobel Prize in chemistry or in physiology or medicine

scientific article published in September 2024

The pleiotropic deubiquitinase Ubp3 confers aneuploidy tolerance

scientific article

Transcriptional consequences of aneuploidy

scientific article

correction:A CRISPR Competition Assay to Identify Cancer Genetic Dependencies

scientific article published in 2021