Search filters

List of works by Larry E. Overman

1,6-Addition of Tertiary Carbon Radicals Generated From Alcohols or Carboxylic Acids by Visible-Light Photoredox Catalysis.

scientific article published on 23 January 2018

A Concise Synthesis of (−)‐Aplyviolene Facilitated by a Strategic Tertiary Radical Conjugate Addition ⬇️

scientific article published on August 24, 2012

A Strategy for Total Synthesis of Complex Cardenolides

scientific article published in October 1996

A general strategy for the synthesis of cladiellin diterpenes: enantioselective total syntheses of 6-acetoxycladiell-7(16),11-dien-3-ol (deacetoxyalcyonin acetate), cladiell-11-ene-3,6,7-triol, sclerophytin A, and the initially purported structure o

scientific article

A new asymmetric synthesis of trans-hydroisoquinolones

scientific article published on 01 April 2001

A unified strategy for enantioselective total synthesis of cladiellin and briarellin diterpenes: total synthesis of briarellins E and F and the putative structure of alcyonin and revision of its structure assignment.

scientific article published on August 2009

A versatile synthesis of unsymmetrical 3,3'-bioxindoles: stereoselective Mukaiyama aldol reactions of 2-siloxyindoles with isatins.

scientific article published on 15 October 2008

Absolute configuration of actinophyllic acid as determined through chiroptical data ⬇️

scientific article

Aloperine: Stereocontrolled Synthesis of Two Stereoisomers and Determination of Absolute Configuration.

scientific article published in February 1997

Application of the Tethered Biginelli Reaction for Enantioselective Synthesis of Batzelladine Alkaloids. Absolute Configuration of the Tricyclic Guanidine Portion of Batzelladine B.

scientific article

Assembling polycyclic bisguanidine motifs resembling batzelladine alkaloids by double tethered Biginelli condensations

scientific article published on 01 November 2003

Asymmetric construction of quaternary carbon stereocenters: high stereoselection in Mukaiyama aldol reactions of 2-siloxyindoles with chiral aldehydes

scientific article published on 01 June 2005

Asymmetric construction of rings A-D of daphnicyclidin-type alkaloids.

scientific article published on December 2009

Asymmetric synthesis of pyrrolidinoindolines. Application for the practical total synthesis of (-)-phenserine

scientific article published in November 2004

Aza-cope rearrangement-mannich cyclizations for the formation of complex tricyclic amines: stereocontrolled total synthesis of (+/-)-gelsemine.

scientific article published on December 2005

Catalytic Asymmetric Rearrangement of Allylic Trichloroacetimidates. A Practical Method for Preparing Allylic Amines and Congeners of High Enantiomeric Purity ⬇️

scientific article (publication date: October 2003)

Catalytic Asymmetric Synthesis of Branched Chiral Allylic Phenyl Ethers from (E)‐Allylic Alcohols ⬇️

scientific article published on December 1, 2009

Catalytic asymmetric intramolecular aminopalladation: enantioselective synthesis of vinyl-substituted 2-oxazolidinones, 2-imidazolidinones, and 2-pyrrolidinones

scientific article published in January 2002

Catalytic asymmetric intramolecular aminopalladation: improved palladium(II) catalysts

scientific article published in April 2005

Catalytic asymmetric rearrangement of allylic N-aryl trifluoroacetimidates. A useful method for transforming prochiral allylic alcohols to chiral allylic amines

scientific article published on 01 May 2003

Catalytic asymmetric synthesis of allylic aryl ethers

scientific article published on 03 February 2007

Catalytic asymmetric synthesis of allylic thiol derivatives.

scientific article

Catalytic asymmetric synthesis of chiral allylic amines. Evaluation of ferrocenyloxazoline palladacycle catalysts and imidate motifs

scientific article published in January 2005

Catalytic asymmetric synthesis of chiral allylic esters

scientific article published on November 2010

Catalytic asymmetric synthesis of quaternary carbons bearing two aryl substituents. Enantioselective synthesis of 3-alkyl-3-aryl oxindoles by catalytic asymmetric intramolecular heck reactions

scientific article

Catalytic enantioselective synthesis of quaternary carbon stereocentres

scientific article

Constructing Quaternary Carbons from N-(Acyloxy)phthalimide Precursors of Tertiary Radicals Using Visible-Light Photocatalysis

scientific article

Constructing quaternary stereogenic centers using tertiary organocuprates and tertiary radicals. Total synthesis of trans-clerodane natural products

scientific article published on 13 January 2015

Construction of epidithiodioxopiperazines by directed oxidation of hydroxyproline-derived dioxopiperazines

scientific article

Construction of substituted cyclohexanones by reductive cyclization of 7-oxo-2,8-alkadienyl esters

scientific article published on 01 January 2002

Correction to "Total Synthesis of (-)-Chromodorolide B By a Computationally-Guided Radical Addition/Cyclization/Fragmentation Cascade"

scientific article published on 24 December 2018

Correction to "Total Synthesis of (-)-Sarain A"

scientific article published on 05 April 2018

Correction to "constructing quaternary stereogenic centers using tertiary organocuprates and tertiary radicals. total synthesis of trans-clerodane natural products"

scientific article published on 02 April 2015

Diastereoselection in the formation of contiguous quaternary carbon stereocenters by the intramolecular Heck reaction.

scientific article published on March 2006

Diastereoselective Coupling of Chiral Acetonide Trisubstituted Radicals with Alkenes.

scientific article published on 29 April 2016

Diastereoselective lithiation of (eta6-arene)dicarbonyltriphenylphosphane chromium(0) oxazoline complexes--direct preparation of enantiopure complexes having planar chiral fragments of either configuration.

scientific article published in October 2002

Direct construction of quaternary carbons from tertiary alcohols via photoredox-catalyzed fragmentation of tert-alkyl N-phthalimidoyl oxalates

scientific article published on 02 October 2013

Divergent synthesis and chemical reactivity of bicyclic lactone fragments of complex rearranged spongian diterpenes

scientific article

Enantioselective Construction of Vicinal Stereogenic Quaternary Centers by Dialkylation: Practical Total Syntheses of (+)- and meso-Chimonanthine.

scientific article published on January 2000

Enantioselective Total Synthesis of Macfarlandin C, a Spongian Diterpenoid Harboring a Concave-Substituted cis-Dioxabicyclo[3.3.0]octanone Fragment

scientific article published on 19 February 2020

Enantioselective syntheses of authentic sclerophytin A, sclerophytin B, and cladiell-11-ene-3,6,7-triol

scientific article published on 01 January 2001

Enantioselective synthesis of angularly substituted 1-azabicyclic ring systems: dynamic kinetic resolution using aza-Cope rearrangements.

scientific article published on March 2010

Enantioselective synthesis of angularly substituted 1-azabicylic rings: coupled dynamic kinetic epimerization and chirality transfer

scientific article

Enantioselective synthesis of six-membered palladacycles having metal-bound stereogenic carbons: isolation and reactivity of palladacycles containing readily accessible beta-hydrogens

scientific article published in December 2004

Enantioselective total syntheses of ditryptophenaline and ent-WIN 64821.

scientific article published in September 2001

Enantioselective total syntheses of nankakurines A and B: confirmation of structure and establishment of absolute configuration.

scientific article published on 2 August 2008

Enantioselective total syntheses of plectosphaeroic acids B and C.

scientific article

Enantioselective total synthesis of (+)-gliocladin C.

scientific article published on January 2007

Enantioselective total synthesis of (+)-gliocladine C: convergent construction of cyclotryptamine-fused polyoxopiperazines and a general approach for preparing epidithiodioxopiperazines from trioxopiperazine precursors.

scientific article

Enantioselective total synthesis of (-)-dehydrobatzelladine C. [structure: see text]

scientific article published on 01 April 2004

Enantioselective total synthesis of batzelladine F and definition of its structure.

scientific article published on March 2006

Enantioselective total synthesis of batzelladine F: structural revision and stereochemical definition

scientific article published in October 2001

Enantioselective total synthesis of briarellins E and F: the first total syntheses of briarellin diterpenes

scientific article published in June 2003

Enantioselective total synthesis of plectosphaeroic acid B

scientific article

Enantioselective total synthesis of quadrigemine C and psycholeine

scientific article published in August 2002

Enantioselective total synthesis of shahamin K.

scientific article published in May 2001

Enantioselective total synthesis of the cyclotryptamine alkaloid idiospermuline

scientific article published on 01 June 2003

Evolution of a strategy for the synthesis of structurally complex batzelladine alkaloids. Enantioselective total synthesis of the proposed structure of batzelladine F and structural revision

scientific article published on March 2006

Facile Preparation of Spirolactones by an Alkoxycarbonyl Radical Cyclization-Cross-Coupling Cascade

scientific article published on 13 May 2019

Forging C(sp)-C(sp) Bonds with Carbon-Centered Radicals in the Synthesis of Complex Molecules

scientific article published on 04 January 2019

Forming tertiary organolithiums and organocuprates from nitrile precursors and their bimolecular reactions with carbon electrophiles to form quaternary carbon stereocenters

scientific article

Fragment Coupling and the Construction of Quaternary Carbons Using Tertiary Radicals Generated From tert-Alkyl N-Phthalimidoyl Oxalates By Visible-Light Photocatalysis

scientific article

General Access to Concave-Substituted cis-Dioxabicyclo[3.3.0]octanones: Enantioselective Total Syntheses of Macfarlandin C and Dendrillolide A

scientific article published on 16 November 2020

General approach for preparing epidithiodioxopiperazines from trioxopiperazine precursors: enantioselective total syntheses of (+)- and (-)-gliocladine C, (+)-leptosin D, (+)-T988C, (+)-bionectin A, and (+)-gliocladin A.

scientific article published on March 2013

Guanidine alkaloid analogs as inhibitors of HIV-1 Nef interactions with p53, actin, and p56lck.

scientific article

H3K9me3 Inhibition Improves Memory, Promotes Spine Formation, and Increases BDNF Levels in the Aged Hippocampus

scientific article published on March 2016

Identification of an Unexpected 2-Oxonia[3,3]sigmatropic Rearrangement/Aldol Pathway in the Formation of Oxacyclic Rings. Total Synthesis of (+)-Aspergillin PZ.

scientific article published on 19 September 2011

Inhibition of HIV-1 envelope-mediated fusion by synthetic batzelladine analogues.

scientific article

Is There No End to the Total Syntheses of Strychnine? Lessons Learned in Strategy and Tactics in Total Synthesis ⬇️

scientific article published on March 19, 2012

Kinetic and computational analysis of the palladium(II)-catalyzed asymmetric allylic trichloroacetimidate rearrangement: development of a model for enantioselectivity

scientific article published on 03 April 2007

Ligand-Controlled Diastereoselective 1,3-Dipolar Cycloadditions of Azomethine Ylides with Methacrylonitrile

scientific article published on 25 November 2015

Mechanism of the cobalt oxazoline palladacycle (COP)-catalyzed asymmetric synthesis of allylic esters.

scientific article

Molecular rearrangements in the construction of complex molecules

scientific article

Monomeric cobalt oxazoline palladacycles (COP). Useful catalysts for catalytic asymmetric rearrangement of allylic trichloroacetimidates

scientific article published in November 2004

New cationic olefin cyclization-pinacol reactions. Ring-expanding cyclopentane annulations that directly install useful functionality in the cyclopentane ring

scientific article published in September 2002

Origin of stereocontrol in the construction of the 12-oxatricyclo[6.3.1.0(2,7)]dodecane ring system by Prins-pinacol reactions

scientific article

Origins of stereoselectivities of dihydroxylations of cis-bicyclo[3.3.0]octenes

scientific article

Oxalates as Activating Groups for Alcohols in Visible Light Photoredox Catalysis: Formation of Quaternary Centers by Redox-Neutral Fragment Coupling

scientific article published on 31 August 2015

Palladacyclic Imidazoline–Naphthalene Complexes: Synthesis and Catalytic Performance in Pd(II)-Catalyzed Enantioselective Reactions of Allylic Trichloroacetimidates ⬇️

scientific article published on January 30, 2012

Palladium(II)-catalyzed enantioselective synthesis of 2-vinyl oxygen heterocycles

scientific article published on 8 February 2012

Preparation of alpha-sulfenyl enones by thermal fragmentation of beta-sulfenyl enol triflates

scientific article published on 01 March 2002

Pumiliotoxin alkaloids: a new class of sodium channel agents

scientific article published in July 1990

Scope and facial selectivity of the Prins-pinacol synthesis of attached rings.

scientific article

Sequential catalytic asymmetric Heck-iminium ion cyclization: enantioselective total synthesis of the Strychnos alkaloid minfiensine

scientific article

Short Enantioselective Total Syntheses of Cheloviolenes A and B and Dendrillolide C via Convergent Fragment Coupling Using a Tertiary Carbon Radical

scientific article published on 13 November 2017

Stereocontrolled construction of either stereoisomer of 12-oxatricyclo[6.3.1.0(2,7)]dodecanes using Prins-pinacol reactions

scientific article published in October 2004

Stereocontrolled enantioselective total synthesis of the [2+2] quadrigemine alkaloids

scientific article published on September 2015

Stereocontrolled synthesis of angularly substituted 1-azabicyclic rings by cationic 2-aza-cope rearrangements

scientific article published on 01 March 2005

Stereocontrolled synthesis of triazacyclopenta[cd]pentalenes by intramolecular 1,3-dipolar cycloaddition reactions of azomethine imines.

scientific article published in November 2002

Stereoselection in the Prins-pinacol synthesis of acyltetrahydrofurans

scientific article published on 01 April 2001

Synthesis and anticancer activity of side chain analogs of the crambescidin alkaloids.

scientific article published on July 2004

Synthesis of 2,5-Diaryl-1,5-dienes from Allylic Bromides Using Visible-Light Photoredox Catalysis

scientific article

Synthesis of all low-energy stereoisomers of the tris(pyrrolidinoindoline) alkaloid hodgkinsine and preliminary assessment of their antinociceptive activity

scientific article

Synthesis of polycyclic guanidines by cyclocondensation reactions of N-amidinyliminium ions

scientific article published in May 2001

Terminating Catalytic Asymmetric Heck Cyclizations by Stereoselective Intramolecular Capture of η-Allylpalladium Intermediates: Total Synthesis of (-)-Spirotryprostatin B and Three Stereoisomers

scientific article published on August 2010

The asymmetric intramolecular Heck reaction in natural product total synthesis

scientific article published in August 2003

The insulin secretory action of novel polycyclic guanidines: discovery through open innovation phenotypic screening, and exploration of structure-activity relationships

scientific article published on 15 January 2014

Thwarting beta-Hydride Elimination: Capture of the Alkylpalladium Intermediate of an Asymmetric Intramolecular Heck Reaction This research was supported by the National Institutes of Health (grant GM-12389). M.O. thanks the Deutsche Forschungsgemein

scientific article

Total Synthesis of (-)-Chromodorolide B By a Computationally-Guided Radical Addition/Cyclization/Fragmentation Cascade.

scientific article published on 7 February 2018

Total synthesis of (+)-condylocarpine, (+)-isocondylocarpine, and (+)-tubotaiwine

scientific article

Total synthesis of (+)-nankakurines A and B and (±)-5-epi-nankakurine A.

scientific article published on 19 October 2010

Total synthesis of (+)-sieboldine A.

scientific article published on June 2010

Total synthesis of (+)-sieboldine a: evolution of a pinacol-terminated cyclization strategy.

scientific article published on 26 June 2012

Total synthesis of (+/-)-didehydrostemofoline (asparagamine A) and (+/-)-isodidehydrostemofoline

scientific article

Total synthesis of (-)-crambidine and definition of the relative configuration of its unique tetracyclic guanidinium core.

scientific article

Total synthesis of (-)-sarain A

scientific article published on 01 April 2006

Total synthesis of (-)-sarain A.

scientific article

Total synthesis of asperazine

scientific article

Total synthesis of complex cyclotryptamine alkaloids: stereocontrolled construction of quaternary carbon stereocenters

scientific article published on January 2007

Total synthesis of the reputed structure of alcyonin and reassignment of its structure

scientific article published on 01 May 2003

Toward an enantioselective total synthesis of sarain A: construction of an advanced intermediate and rearrangement of the sarain A core under mild conditions

scientific article published on 01 March 2005

Tricyclic Analogues of Epidithiodioxopiperazine Alkaloids with Promising In Vitro and In Vivo Antitumor Activity

scientific article published on January 2015

Tuning Stereoselection in Tethered Biginelli Condensations. Synthesis of cis- or trans-1-Oxo- and 1-Iminohexahydropyrrolo[1,2-c]pyrimidines

scientific article published in March 1999

Use of the intramolecular Heck reaction for forming congested quaternary carbon stereocenters. Stereocontrolled total synthesis of (+/-)-gelsemine.

scientific article published on December 2005

Versatile Construction of 6-Substituted cis-2,8-Dioxabicyclo[3.3.0]octan-3-ones: Short Enantioselective Total Syntheses of Cheloviolenes A and B and Dendrillolide C.

scientific article published on 17 May 2017

Paulina is supported by:

About Paulina

Help