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List of works by Erika L. Pearce

A Sweet Deal for Diabetes

scientific article

A common framework of monocyte-derived macrophage activation

scientific article published on 15 April 2022

A metabolic interplay coordinated by HLX regulates myeloid differentiation and AML through partly overlapping pathways

scientific article published in Nature Communications

Acetate Promotes T Cell Effector Function during Glucose Restriction.

scientific article

Amino Assets: How Amino Acids Support Immunity

scientific article published on 02 July 2020

Ancillary Activity: Beyond Core Metabolism in Immune Cells

scientific article published in July 2017

Appetite for Arginine: Metabolic Control of Macrophage Hunger

scientific article published on 01 March 2020

Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation

scientific article published on 04 April 2016

Autophagy is essential for effector CD8(+) T cell survival and memory formation

scientific article

Bile acids regulate intestinal antigen presentation and reduce graft-versus-host disease without impairing the graft-versus-leukemia effect

scientific article published on 16 July 2020

CD8 memory T cells have a bioenergetic advantage that underlies their rapid recall ability.

scientific article published on 12 August 2013

Caught in the cROSsfire: GSH Controls T Cell Metabolic Reprogramming

scientific article published on April 2017

Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages

scientific article

Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens

scientific article

Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells.

scientific article

Control of Effector CD8 + T Cell Function by the Transcription Factor Eomesodermin ⬇️

scientific article published on November 7, 2003

Cutting edge: requirement for TRAF6 in the induction of T cell anergy

scientific article published on 01 January 2008

Dynamic Cardiolipin Synthesis Is Required for CD8<sup>+</sup> T Cell Immunity

scientific article published on 01 December 2020

EBF1 and Pax5 safeguard leukemic transformation by limiting IL-7 signaling, Myc expression, and folate metabolism

scientific article published on 01 October 2020

Emerging concepts of T cell metabolism as a target of immunotherapy.

scientific article published on March 2016

Enhancing CD8 T-cell memory by modulating fatty acid metabolism

scientific article

Erratum: Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells

scientific article published on 01 April 2018

Fatty acid oxidation is essential for egg production by the parasitic flatworm Schistosoma mansoni

scientific article

Fatty acid synthesis tips the TH17-Treg cell balance

scientific article published on 01 November 2014

Functional characterization of MHC class II-restricted CD8+CD4- and CD8-CD4- T cell responses to infection in CD4-/- mice

scientific article

Generation of CD8 T cell memory is regulated by IL-12.

scientific article published in August 2007

Helper T cell differentiation and the problem of cellular inheritance

scientific article

Host dysbiosis negatively impacts IL-9-producing T-cell differentiation and antitumour immunity

scientific article published on 05 June 2020

IL-18 synergizes with IL-7 to drive slow proliferation of naive CD8 T cells by costimulating self-peptide-mediated TCR signals

scientific article

IL-33 expression in response to SARS-CoV-2 correlates with seropositivity in COVID-19 convalescent individuals

scholarly article by Michal A Stanczak published in 2021

Immunology. Expanding the role of metabolism in T cells

scientific article published in May 2015

Immunometabolism in 2017: Driving immunity: all roads lead to metabolism.

scientific article published on 11 December 2017

Inflammatory macrophage dependence on NAD+ salvage is a consequence of reactive oxygen species-mediated DNA damage

scientific article published on 11 March 2019

Inhibition of mechanistic target of rapamycin promotes dendritic cell activation and enhances therapeutic autologous vaccination in mice.

scientific article published on 23 July 2012

MZB1 enables efficient interferon α secretion in stimulated plasmacytoid dendritic cells

scientific article published on 14 December 2020

Making sense of inflammation, epigenetics, and memory CD8+ T-cell differentiation in the context of infection

scientific article published on June 2006

Measuring Bioenergetics in T Cells Using a Seahorse Extracellular Flux Analyzer

scientific article published on April 2016

Mechanistic target of rapamycin inhibition extends cellular lifespan in dendritic cells by preserving mitochondrial function.

scientific article

Memory CD8 T Cells Use Cell-Intrinsic Lipolysis to Support the Metabolic Programming Necessary for Development

article

Memory CD8(+) T cells use cell-intrinsic lipolysis to support the metabolic programming necessary for development.

scientific article

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression

scientific article published on 26 August 2015

Metabolic Dynamics of In Vitro CD8+ T Cell Activation

scientific article published on 28 December 2020

Metabolic Instruction of Immunity.

scientific article published on May 2017

Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation

scientific article published on October 2016

Metabolic Reprogramming Overcomes T Cell Inhibition By AML Cells ⬇️

scholarly article

Metabolic conditioning of CD8+ effector T cells for adoptive cell therapy

scientific article published on 03 August 2020

Metabolic interventions in the immune response to cancer

scientific article published on 01 May 2019

Metabolic pathways in immune cell activation and quiescence

scientific article published on April 2013

Metabolic reprogramming of donor T cells enhances graft-versus-leukemia effects in mice and humans

scientific article published on 01 October 2020

Metabolic switching and fuel choice during T-cell differentiation and memory development

scientific article published on September 2012

Metabolism in T cell activation and differentiation

scientific article published on 26 February 2010

Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming.

scientific article published on 8 June 2016

Mitochondrial Dynamics at the Interface of Immune Cell Metabolism and Function

scientific article published on 8 September 2017

Mitochondrial Integrity Regulated by Lipid Metabolism Is a Cell-Intrinsic Checkpoint for Treg Suppressive Function

scientific article published on 26 December 2019

Mitochondrial Membrane Potential Regulates Nuclear Gene Expression in Macrophages Exposed to Prostaglandin E2

scientific article published on 01 December 2018

Mitochondrial Priming by CD28.

scientific article

Mitochondrial Pyruvate Import Promotes Long-Term Survival of Antibody-Secreting Plasma Cells

scientific article published on July 2016

Mitochondrial respiratory capacity is a critical regulator of CD8+ T cell memory development

scientific article

Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity

article published in 2022

Oncogenic JAK2V617F causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms.

scientific article published in February 2018

Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity

scientific article published on 21 November 2019

Polyamine metabolism is a central determinant of helper T cell lineage fidelity

scientific article published in 2021

Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation

scientific article published on 23 May 2019

Posttranscriptional control of T cell effector function by aerobic glycolysis

scientific article

Potassium shapes antitumor immunity

scientific article published on 01 March 2019

Resident T cells orchestrate adipose tissue remodeling in a site peripheral to infection

scientific article published on 26 February 2022

Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

scientific article published on 12 February 2018

Sulfur sequestration promotes multicellularity during nutrient limitation

scientific article published on 24 February 2021

T cell metabolism drives immunity

scientific article

TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation

scientific article

TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2.

scientific article

Targeting T cell metabolism for therapy

scientific article

Th1 and Th2 cells help CD8 T-cell responses

scientific article published on 26 February 2007

The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites

scientific article

The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites

scientific article published on 01 November 2016

The energy sensor AMPK regulates T cell metabolic adaptation and effector responses in vivo

scientific article published on 2 January 2015

The importance of methionine metabolism

scientific article published on 02 May 2019

Tonic TCR Signaling Inversely Regulates the Basal Metabolism of CD4+ T Cells

scientific article published on 07 August 2020

Triacylglycerol synthesis enhances macrophage inflammatory function

scientific article published on 14 August 2020

Type 1 Interferons Induce Changes in Core Metabolism that Are Critical for Immune Function

scientific article published on June 2016

Unraveling the Complex Interplay Between T Cell Metabolism and Function.

scientific article published in April 2018

When Hexokinase Gets that NAG-ing Feeling….

scientific article published on August 2016

c-Myc-induced transcription factor AP4 is required for host protection mediated by CD8+ T cells

scientific article

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