Search filters

List of works by Wen Xue

A flexible split prime editor using truncated reverse transcriptase improves dual-AAV delivery in mouse liver

scientific article published in 2022

A split prime editor with untethered reverse transcriptase and circular RNA template

scientific article published in 2022

Adenine base editing in an adult mouse model of tyrosinaemia

scientific article published on 25 February 2019

CRISPR-Cas: a tool for cancer research and therapeutics

scientific article published on 01 May 2019

CRISPR-SONIC: targeted somatic oncogene knock-in enables rapid in vivo cancer modeling

scientific article published on 16 April 2019

CRISPR-mediated direct mutation of cancer genes in the mouse liver

scientific article

CRISPR/Cas9-mediated genome editing induces exon skipping by alternative splicing or exon deletion

scientific article published on 14 June 2017

Cas9-mediated allelic exchange repairs compound heterozygous recessive mutations in mice

scientific article published on 13 August 2018

Caspase-2-Mediated Cleavage of Mdm2 Creates a p53-Induced Positive Feedback Loop ⬇️

scientific article published on July 8, 2011

Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope

scientific article published on 24 April 2020

Enrichment of transcriptional regulatory sites in non-coding genomic region.

scientific article published on 22 January 2004

Generation and analysis of genetically defined liver carcinomas derived from bipotential liver progenitors

scientific article

Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype.

scientific article

Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice

scientific article published on 09 April 2021

KRAS and YAP1 converge to regulate EMT and tumor survival

scientific article

Partial DNA-guided Cas9 enables genome editing with reduced off-target activity.

scientific article

Rapid modelling of cooperating genetic events in cancer through somatic genome editing

scientific article

Self-inactivating, all-in-one AAV vectors for precision Cas9 genome editing via homology-directed repair in vivo

scientific article published on 01 November 2021

Small RNA combination therapy for lung cancer

scientific article

Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing.

scientific article published on 13 November 2017

Targeting cadherin-17 inactivates Wnt signaling and inhibits tumor growth in liver carcinoma

scientific article published in November 2009

Tissue-restricted genome editing in vivo specified by microRNA-repressible anti-CRISPR proteins

scientific article published on 22 August 2019

Topoisomerase levels determine chemotherapy responsein vitroandin vivo

scientific article (publication date: 23 June 2008)

Understanding and repurposing CRISPR-mediated alternative splicing

scientific article published on 06 November 2018

p53-dependent Nestin regulation links tumor suppression to cellular plasticity in liver cancer

scientific article

Paulina is supported by:

About Paulina

Help