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List of works by Stewart Cole

2-Carboxyquinoxalines kill mycobacterium tuberculosis through noncovalent inhibition of DprE1

scientific article

6,11-Dioxobenzo[f]pyrido[1,2-a]indoles kill Mycobacterium tuberculosis by targeting iron-sulfur protein Rv0338c (IspQ) a putative redox sensor

scientific article published on 15 September 2020

A comprehensive survey of single nucleotide polymorphisms (SNPs) across Mycobacterium bovis strains and M. bovis BCG vaccine strains refines the genealogy and defines a minimal set of SNPs that separate virulent M. bovis strains and M. bovis BCG str

scientific article

A method for rapid detection of rifampicin-resistant isolates of Mycobacterium leprae. ⬇️

scientific article published in December 2001

A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK.

scientific article published on 16 February 2018

A new paradigm for leprosy diagnosis based on host gene expression

scientific article published on 25 October 2021

A new synthetic access to furo[3,2-f]chromene analogues of an antimycobacterial

scientific article published on 3 August 2008

A novel drug discovery concept for tuberculosis: inhibition of bacterial and host cell signalling.

scientific article

A point mutation in cycA partially contributes to the D-cycloserine resistance trait of Mycobacterium bovis BCG vaccine strains

scientific article

A point mutation in the two-component regulator PhoP-PhoR accounts for the absence of polyketide-derived acyltrehaloses but not that of phthiocerol dimycocerosates in Mycobacterium tuberculosis H37Ra

scientific article

A protein linkage map of the ESAT-6 secretion system 1 (ESX-1) of Mycobacterium tuberculosis

scientific article published on 12 April 2007

A strategy to halt leprosy transmission

scientific article published on February 2014

A structure-guided fragment-based approach for the discovery of allosteric inhibitors targeting the lipophilic binding site of transcription factor EthR.

scientific article

Activation and regulation of Toll-like receptors 2 and 1 in human leprosy

scientific article published on 14 April 2003

Advances in the development of new tuberculosis drugs and treatment regimens

scientific article published on May 2013

An increase in antimycobacterial Th1-cell responses by prime-boost protocols of immunization does not enhance protection against tuberculosis

scientific article

Ancient genomes reveal a high diversity of Mycobacterium leprae in medieval Europe.

scientific article

Anticytolytic screen identifies inhibitors of mycobacterial virulence protein secretion.

scientific article

Antigen discovery: a postgenomic approach to leprosy diagnosis

scientific article

Antimalarial and antitubercular nostocarboline and eudistomin derivatives: synthesis, in vitro and in vivo biological evaluation

scientific article published on 11 January 2010

Antimicrobial drug discovery

scientific article published in June 2011

Antimycobacterial Benzofuro[3,2-f]chromenes from a 5-Bromochromen-6-ol

Application of broad-spectrum resequencing microarray for genotyping rhabdoviruses

scientific article

Application of high-density DNA resequencing microarray for detection and characterization of botulinum neurotoxin-producing clostridia

scientific article

Aquatic snails, passive hosts of Mycobacterium ulcerans

scientific article published on October 2004

Are the PE-PGRS proteins of Mycobacterium tuberculosis variable surface antigens?

scientific journal article

Are variable-number tandem repeats appropriate for genotyping Mycobacterium leprae?

scientific article

Arylvinylpiperazine Amides, a New Class of Potent Inhibitors Targeting QcrB of Mycobacterium tuberculosis

scientific article published on 09 October 2018

Assessing essentiality of transketolase in Mycobacterium tuberculosis using an inducible protein degradation system

scientific article

Assessing the essentiality of the decaprenyl-phospho-d-arabinofuranose pathway in Mycobacterium tuberculosis using conditional mutants

scientific article published on 7 March 2014

Atypical DNA recognition mechanism used by the EspR virulence regulator of Mycobacterium tuberculosis ⬇️

scientific article published on September 12, 2011

Bacterial artificial chromosome-based comparative genomic analysis identifies Mycobacterium microti as a natural ESAT-6 deletion mutant

scientific article

Benzofuro[3,2-f][1]benzopyrans: A new class of antitubercular agents

scientific article published on 17 April 2006

Benzothiazinones are suicide inhibitors of mycobacterial decaprenylphosphoryl-β-D-ribofuranose 2'-oxidase DprE1.

scientific article

Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis

scientific journal article

Benzothiazinones: prodrugs that covalently modify the decaprenylphosphoryl-β-D-ribose 2'-epimerase DprE1 of Mycobacterium tuberculosis

scientific article published on October 2010

Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance

scientific article

Bioluminescence for assessing drug potency against nonreplicating Mycobacterium tuberculosis

scientific article published on 20 April 2015

British Red Squirrels Remain the Only Known Wild Rodent Host for Leprosy Bacilli

Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans

scientific article published on January 2009

Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans

article

Case of diffuse lepromatous leprosy associated with "Mycobacterium lepromatosis".

scientific article published on 19 October 2011

Celebrating 130 years of achievement by the Institut Pasteur

scientific article published on 25 April 2019

Celebrating 130 years of achievement by the Institut Pasteur

scientific article published on 01 June 2019

Characterization of Active Site Structure in CYP121: A CYTOCHROME P450 ESSENTIAL FOR VIABILITY OF MYCOBACTERIUM TUBERCULOSIS H37Rv

scientific article

Characterization of DprE1-Mediated Benzothiazinone Resistance in Mycobacterium tuberculosis

scientific article published on 15 August 2016

Clinical isolates of Mycobacterium tuberculosis in four European hospitals are uniformly susceptible to benzothiazinones

scientific article

Colonization of the salivary glands of Naucoris cimicoides by Mycobacterium ulcerans requires host plasmatocytes and a macrolide toxin, mycolactone

scientific article

Common evolutionary origin for the unstable virulence plasmid pMUM found in geographically diverse strains of Mycobacterium ulcerans

scientific article

Comparative Genomics ofesxGenes from Clinical Isolates of Mycobacterium tuberculosis Provides Evidence for Gene Conversion and Epitope Variation ⬇️

scientific article published on August 1, 2011

Comparative and functional genomics of the Mycobacterium tuberculosis complex

scientific article

Comparative genomic and phylogeographic analysis of Mycobacterium leprae

article

Comparison of target enrichment strategies for ancient pathogen DNA

scientific article published on 02 November 2020

Comprehensive proteome analysis of Mycobacterium ulcerans and quantitative comparison of mycolactone biosynthesis

scientific article

Conserved autophosphorylation pattern in activation loops and juxtamembrane regions of Mycobacterium tuberculosis Ser/Thr protein kinases

scientific article published in August 2005

Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP

scientific journal article

Cross-resistance between clofazimine and bedaquiline through upregulation of MmpL5 in Mycobacterium tuberculosis

scientific article published on 3 March 2014

Database resources for the tuberculosis community

scientific article published on 17 January 2013

Design and Synthesis of Pyrano[3,2-<i>b</i>]indolones Showing Antimycobacterial Activity

scientific article published on 22 December 2020

Detection and strain typing of ancient Mycobacterium leprae from a medieval leprosy hospital.

scientific article

Detection and treatment of subclinical tuberculosis

article

Development and validation of a multiplex UHPLC-MS/MS method for the determination of the investigational antibiotic against multi-resistant tuberculosis macozinone (PBTZ169) and five active metabolites in human plasma

scientific article published on 31 May 2019

Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis

scientific article published on 05 March 2016

Development of a repressible mycobacterial promoter system based on two transcriptional repressors

scientific article published on 20 April 2010

Differential effects of prior exposure to environmental mycobacteria on vaccination with Mycobacterium bovis BCG or a recombinant BCG strain expressing RD1 antigens

scientific article

Discovery and Biosynthesis of Gladiolin: A Burkholderia gladioli Antibiotic with Promising Activity against Mycobacterium tuberculosis ⬇️

scientific article published on 22 May 2017

Discovery of benzothiazoles as antimycobacterial agents: Synthesis, structure-activity relationships and binding studies with Mycobacterium tuberculosis decaprenylphosphoryl-β-D-ribose 2'-oxidase

scientific article

Dissecting regulatory networks in host-pathogen interaction using chIP-on-chip technology

scientific article published on May 2009

Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence

scientific article

Diversity-oriented synthesis of furo[3,2-f]chromanes with antimycobacterial activity

scientific article published on 29 January 2009

DprE1 Is a Vulnerable Tuberculosis Drug Target Due to Its Cell Wall Localization

scientific article published on 29 April 2015

Drug-resistant tuberculosis: time for visionary political leadership

scientific article

ERRATUM

scientific article published in 1990

ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membrane-lysing activity

scientific article published on 8 June 2007

ESAT-6 secretion-independent impact of ESX-1 genes espF and espG1 on virulence of Mycobacterium tuberculosis

scientific journal article

Early trafficking events of Mycobacterium ulcerans within Naucoris cimicoides

scientific article published on 24 August 2006

Effect of katG mutations on the virulence of Mycobacterium tuberculosis and the implication for transmission in humans.

scientific article

Elimination of PknL and MSMEG_4242 in <i>Mycobacterium smegmatis</i> alters the character of the outer cell envelope and selects for mutations in Lsr2

scientific article published on 25 August 2021

Emergence of Mycobacterium leprae rifampicin resistance evaluated by whole-genome sequencing after 48 years of irregular treatment

scientific article published on 27 April 2020

Erratum for Boldrin et al., The Phosphatidyl-myo-Inositol Mannosyltransferase PimA Is Essential for Mycobacterium tuberculosis Growth In Vitro and In Vivo.

scientific article published in December 2014

Erratum: Corrigendum: Comparative genomic and phylogeographic analysis of Mycobacterium leprae

scholarly article published in Nature Genetics

EspC forms a filamentous structure in the cell envelope of Mycobacterium tuberculosis and impacts ESX-1 secretion

scientific article published on 10 November 2016

EspD is critical for the virulence-mediating ESX-1 secretion system in Mycobacterium tuberculosis.

scientific article published on 9 December 2011

EspI regulates the ESX-1 secretion system in response to ATP levels in Mycobacterium tuberculosis

scientific article

EspL is essential for virulence and stabilizes EspE, EspF and EspH levels in Mycobacterium tuberculosis

scientific article published on 20 December 2018

Essential Nucleoid Associated Protein mIHF (Rv1388) Controls Virulence and Housekeeping Genes in Mycobacterium tuberculosis

scientific article published in Scientific Reports

Essentiality of mmpL3 and impact of its silencing on Mycobacterium tuberculosis gene expression

scientific article published on 27 February 2017

Evaluation of Auramine O staining and conventional PCR for leprosy diagnosis: A comparative cross-sectional study from Ethiopia

scholarly article by Selfu Girma et al published September 2018 in PLoS Neglected Tropical Diseases

Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis

scientific article published on 20 January 2005

Evidence of zoonotic leprosy in Pará, Brazilian Amazon, and risks associated with human contact or consumption of armadillos.

scientific article published on 28 June 2018

FasR Regulates Fatty Acid Biosynthesis and Is Essential for Virulence of Mycobacterium tuberculosis

scientific article published on 27 October 2020

Fluorescent Benzothiazinone Analogues Efficiently and Selectively Label Dpre1 in Mycobacteria and Actinobacteria

scholarly article by Raphael Sommer et al published 5 October 2018 in ACS Chemical Biology

Fluorescent benzothiazinone analogs efficiently and selectively label DprE1 in mycobacteria and actinobacteria

From functional genomics to systems (micro)biology

Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans

scientific article

Functional analysis of early secreted antigenic target-6, the dominant T-cell antigen of Mycobacterium tuberculosis, reveals key residues involved in secretion, complex formation, virulence, and immunogenicity

scientific article published on 27 July 2005

Functional dissection of intersubunit interactions in the EspR virulence regulator of Mycobacterium tuberculosis

scientific article

Genome plasticity of BCG and impact on vaccine efficacy

scientific article

Genome-Wide Comparison of Medieval and Modern Mycobacterium leprae

scientific article (publication date: 13 June 2013)

Genome-wide definition of the SigF regulon in Mycobacterium tuberculosis

scientific article published on 3 February 2012

Genome-wide regulon and crystal structure of BlaI (Rv1846c) from Mycobacterium tuberculosis

scientific article

Genomic Characterization of Mycobacterium leprae to Explore Transmission Patterns Identifies New Subtype in Bangladesh

scientific article published on 16 June 2020

Genomic and transcriptomic analysis of the streptomycin-dependent Mycobacterium tuberculosis strain 18b.

scientific article

Genomics ofMycobacterium Tuberculosis and Mycobacterium Leprae

scholarly article

Genotypic analysis of Mycobacterium tuberculosis in Bangladesh and prevalence of the Beijing strain

scientific article

Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans ⬇️

scientific article

GtrA Protein Rv3789 Is Required for Arabinosylation of Arabinogalactan in Mycobacterium tuberculosis

scientific article published on 14 September 2015

High content screening identifies decaprenyl-phosphoribose 2' epimerase as a target for intracellular antimycobacterial inhibitors

scientific article

High resolution CryoEM structure of the ring-shaped virulence factor EspB from Mycobacterium tuberculosis

scientific article published on 02 July 2020

High-resolution detection of DNA binding sites of the global transcriptional regulator GlxR in Corynebacterium glutamicum

scientific article published on 25 October 2012

High-resolution transcriptome and genome-wide dynamics of RNA polymerase and NusA in Mycobacterium tuberculosis

scientific article published on 7 December 2012

Highly Reduced Genome of the New Species , the Causative Agent of Nodular Thelitis and Tuberculoid Scrotitis in Livestock and a Close Relative of the Leprosy Bacilli

scientific article published on 03 October 2018

Identification of Specific Proteins and Peptides in Mycobacterium leprae Suitable for the Selective Diagnosis of Leprosy

scientific article published on 01 December 2005

Identification of aminopyrimidine-sulfonamides as potent modulators of Wag31-mediated cell elongation in mycobacteria

scientific article published on 28 September 2016

Identification using LC-MSn of co-metabolites in the biosynthesis of the polyketide toxin mycolactone by a clinical isolate of Mycobacterium ulcerans

scientific article

Immunogenic membrane-associated proteins of Mycobacterium tuberculosis revealed by proteomics

scientific article published in July 2005

Immunogenicity of Mycobacterium ulcerans Hsp65 and protective efficacy of a Mycobacterium leprae Hsp65-based DNA vaccine against Buruli ulcer

scientific article published on 24 May 2006

Impact of Mycobacterium ulcerans biofilm on transmissibility to ecological niches and Buruli ulcer pathogenesis

scientific article

In Vitro Activities of the New Antitubercular Agents PA-824 and BTZ043 against Nocardia brasiliensis ⬇️

scientific article published on April 23, 2012

In Vivo Activity of the Benzothiazinones PBTZ169 and BTZ043 against Nocardia brasiliensis

scientific article

In vitro Controlled Release from Solid Pharmaceutical Formulations of two new Adamantane Aminoethers with Antitubercular Activity (I).

scientific article published on 30 May 2017

In vitro and in vivo activities of three oxazolidinones against nonreplicating Mycobacterium tuberculosis

scientific article

In vitro combination studies of benzothiazinone lead compound BTZ043 against Mycobacterium tuberculosis

scientific article published on 27 August 2012

Inactivation of Rv2525c, a substrate of the twin arginine translocation (Tat) system of Mycobacterium tuberculosis, increases beta-lactam susceptibility and virulence

scientific journal article

Infectious diseases: Transporter targeted in tuberculosis

scientific article published on 16 March 2012

Inhibiting Mycobacterium tuberculosis within and without

scientific article published on November 2016

Insight into the evolution and origin of leprosy bacilli from the genome sequence of Mycobacterium lepromatosis

scientific article

Insights from the Genome Sequence of Mycobacterium lepraemurium: Massive Gene Decay and Reductive Evolution

scientific article published on 17 October 2017

Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis

scientific article

Isolation of three Mycobacterium ulcerans strains resistant to rifampin after experimental chemotherapy of mice

scientific article

Lack of insertional-deletional polymorphism in a collection of mycobacterium ulcerans isolates from Ghanaian buruli ulcer patients

scientific article published on 02 September 2009

Lansoprazole is an antituberculous prodrug targeting cytochrome bc1.

scientific article

Lead selection and characterization of antitubercular compounds using the Nested Chemical Library

scientific article published on 28 February 2015

Leads for antitubercular compounds from kinase inhibitor library screens

scientific journal article

Leprosy in red squirrels in the UK

scientific article published on 01 March 2019

Leprosy in wild chimpanzees

scientific article published in 2021

Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti

scientific article published in November 2002

Massively parallel pathogen identification using high-density microarrays

scientific article published on January 2008

Mechanism of action of 5-nitrothiophenes against Mycobacterium tuberculosis

scientific article published on 18 February 2014

Microbiology. Pyrazinamide--old TB drug finds new target

scientific article published on 01 September 2011

Microbiology. TB--a new target, a new drug

scientific article published in January 2005

Micrococcin P1 - A bactericidal thiopeptide active against Mycobacterium tuberculosis

scientific article published on 27 July 2016

Mode of Action of Clofazimine and Combination Therapy with Benzothiazinones against Mycobacterium tuberculosis

scientific article published on 18 May 2015

Modulation of the host immune response by a transient intracellular stage of Mycobacterium ulcerans: the contribution of endogenous mycolactone toxin

scientific article published on August 2005

Molecular drug susceptibility testing and genotyping of Mycobacterium leprae strains from South America

scientific article

Monitoring Tuberculosis Drug Activity in Live Animals by Near-Infrared Fluorescence Imaging

scientific article published on 16 September 2019

Multicenter analysis of sputum microbiota in tuberculosis patients

scientific article published on 12 October 2020

Multitarget drug discovery for tuberculosis and other infectious diseases

scientific article

Mycobacterial Ser/Thr protein kinases and phosphatases: physiological roles and therapeutic potential.

scientific article published on 14 August 2007

Mycobacterium leprae diversity and population dynamics in medieval Europe from novel ancient genomes

scientific article published in 2021

Mycobacterium leprae genomes from a British medieval leprosy hospital: towards understanding an ancient epidemic

scientific article

Mycobacterium leprae genotype amplified from an archaeological case of lepromatous leprosy in Central Asia

article

Mycobacterium leprae: genes, pseudogenes and genetic diversity

scientific article

Mycobacterium lepromatosis Infections in Nuevo León, Mexico.

scientific article published on 25 March 2015

Mycobacterium tuberculosis Differentially Activates cGAS- and Inflammasome-Dependent Intracellular Immune Responses through ESX-1.

scientific article published on 2 June 2015

Mycobacterium tuberculosis EspB binds phospholipids and mediates EsxA-independent virulence.

scientific article published on 15 August 2013

Mycobacterium tuberculosis and the host response

scientific article

NOS2-deficient mice with hypoxic necrotizing lung lesions predict outcomes of tuberculosis chemotherapy in humans

scientific article published on 18 August 2017

Nature's magic bullets

scientific article published in Nature

New 1-hydroxy-2-thiopyridine derivatives active against both replicating and dormant Mycobacterium tuberculosis

scientific article published on 17 May 2017

New 2-Ethylthio-4-methylaminoquinazoline derivatives inhibiting two subunits of cytochrome bc1 in Mycobacterium tuberculosis

scientific article published on 23 January 2020

New antituberculosis drugs, regimens, and adjunct therapies: needs, advances, and future prospects

scientific article published on April 2014

New approaches to filling the gap in tuberculosis drug discovery

scientific article

New tuberculosis drugs on the horizon

scientific article published on 05 August 2011

On the Origin of Leprosy

scientific article

Optimized Background Regimen for Treatment of Active Tuberculosis with the Next-Generation Benzothiazinone Macozinone (PBTZ169)

scientific article published on 24 October 2018

Phenotypic profiling of Mycobacterium tuberculosis EspA point mutants reveals that blockage of ESAT-6 and CFP-10 secretion in vitro does not always correlate with attenuation of virulence.

scientific article published on 27 September 2013

Phi29 polymerase based random amplification of viral RNA as an alternative to random RT-PCR

scientific article

Phylogenomics and antimicrobial resistance of the leprosy bacillus Mycobacterium leprae

scientific article

PknB kinase activity is regulated by phosphorylation in two Thr residues and dephosphorylation by PstP, the cognate phospho-Ser/Thr phosphatase, in Mycobacterium tuberculosis

scientific article published in September 2003

Polarly Localized EccE1 Is Required for ESX-1 Function and Stabilization of ESX-1 Membrane Proteins in Mycobacterium tuberculosis

scientific article published on 11 February 2020

Population Genomics of Mycobacterium leprae Reveals a New Genotype in Madagascar and the Comoros

scientific article published on 11 May 2020

Primer-initiated sequence synthesis to detect and assemble structural variants.

scientific article published on 13 June 2010

Probable zoonotic leprosy in the southern United States

scientific article

Promoter mutagenesis for fine-tuning expression of essential genes in Mycobacterium tuberculosis

scientific article

Protection against Mycobacterium ulcerans lesion development by exposure to aquatic insect saliva

scientific article

Proteome analysis of the plasma membrane of Mycobacterium tuberculosis

scientific article

Pyridomycin bridges the NADH- and substrate-binding pockets of the enoyl reductase InhA

scientific article

Rapid and simple approach for identification of Mycobacterium tuberculosis complex isolates by PCR-based genomic deletion analysis

scientific article

Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv

scientific article

Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis

scientific article published on 14 April 2003

Reconstructed ancestral sequences improve pathogen identification using resequencing DNA microarrays

scientific article (publication date: 20 December 2010)

Red squirrels in the British Isles are infected with leprosy bacilli.

scientific article published on November 2016

Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer

scientific article published on 8 January 2007

Rising standards for tuberculosis drug development

scientific article published on 15 September 2008

Royal Society of Tropical Medicine and Hygiene Meeting at Manson House, London, 18th January 2001. Pathogen genomes and human health. Mycobacterial genomics

scientific article published on January 2002

Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis

scientific article

Rv3852 (H-NS) of Mycobacterium tuberculosis Is Not Involved in Nucleoid Compaction and Virulence Regulation

scientific article

Scaling up interventions to achieve global tuberculosis control: progress and new developments

scientific article published on May 2012

Selective suppression of dendritic cell functions by Mycobacterium ulcerans toxin mycolactone

scientific article

Sigma factor F does not prevent rifampin inhibition of RNA polymerase or cause rifampin tolerance in Mycobacterium tuberculosis

scientific article published on 20 August 2010

Simple model for testing drugs against nonreplicating Mycobacterium tuberculosis

scientific article

Streptomycin-starved Mycobacterium tuberculosis 18b, a drug discovery tool for latent tuberculosis

scientific article

Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium tuberculosis

scientific article

Structural and DNA binding properties of mycobacterial integration host factor mIHF

scientific article published on 14 December 2019

Structural studies of Mycobacterium tuberculosis DprE1 interacting with its inhibitors

scientific article published on 22 September 2016

Structural studies suggest a peptidoglycan hydrolase function for the Mycobacterium tuberculosis Tat-secreted protein Rv2525c

scientific article

Structure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzyme ⬇️

scientific article published on January 1, 2012

Structure and mechanism of the alkyl hydroperoxidase AhpC, a key element of the Mycobacterium tuberculosis defense system against oxidative stress

scientific article published on 10 May 2005

Structure of EspB, a secreted substrate of the ESX-1 secretion system of Mycobacterium tuberculosis

scientific article published on 4 June 2015

Structure-Based Drug Design and Characterization of Sulfonyl-Piperazine Benzothiazinone Inhibitors of DprE1 from Mycobacterium tuberculosis

scholarly article by Jérémie Piton et al published October 2018 in Antimicrobial Agents and Chemotherapy

Structure-based drug design and characterization of sulfonyl-piperazine benzothiazinone inhibitors of DprE1 fromMycobacterium tuberculosis

scholarly article published 10 April 2018

Synthesis and Structure-Activity Relationship Studies of C2-Modified Analogs of the Antimycobacterial Natural Product Pyridomycin

scientific article published on 21 January 2020

Synthesis and antimycobacterial activity of 2,1'-dihydropyridomycins

scientific article

Synthesis and antimycobacterial evaluation of benzofurobenzopyran analogues

scientific article published on 12 December 2006

Synthesis of Adamantane Aminoethers with Antitubercular Potential

scientific article published on 01 January 2017

Synthesis of diphenoxyadamantane alkylamines with pharmacological interest

scientific article published on 06 April 2019

Systematic genetic nomenclature for type VII secretion systems.

scientific article

The 8-Pyrrole-Benzothiazinones Are Noncovalent Inhibitors of DprE1 from Mycobacterium tuberculosis

scientific article published on 18 May 2015

The Crystal Structure of Rv0813c from Mycobacterium tuberculosis Reveals a New Family of Fatty Acid-Binding Protein-Like Proteins in Bacteria

scientific article

The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis

scientific article

The MycoBrowser portal: a comprehensive and manually annotated resource for mycobacterial genomes

scientific article published on October 25, 2010

The Mycobacteria: a Postgenomic View

The PE and PPE Protein Families of Mycobacterium tuberculosis

scholarly article published 18 September 2017

The PhoP-dependent ncRNA Mcr7 modulates the TAT secretion system in Mycobacterium tuberculosis.

scientific article

The Ser/Thr protein kinase PknB is essential for sustaining mycobacterial growth

scientific journal article

The complete genome sequence of Mycobacterium bovis

scientific article

The crystal structure ofM. lepraeML2640c defines a large family of putative S-adenosylmethionine-dependent methyltransferases in mycobacteria

scientific article

The crystal structures of apo and cAMP-bound GlxR from Corynebacterium glutamicum reveal structural and dynamic changes upon cAMP binding in CRP/FNR family transcription factors

scientific journal article

The cysteine desulfurase IscS of Mycobacterium tuberculosis is involved in iron-sulfur cluster biogenesis and oxidative stress defence

scientific article

The phosphatidyl-myo-inositol mannosyltransferase PimA is essential for Mycobacterium tuberculosis growth in vitro and in vivo

scientific article

Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG

scientific article published on 18 June 2015

Total Synthesis of Ripostatin B and Structure-Activity Relationship Studies on Ripostatin Analogs.

scientific article

Towards a new combination therapy for tuberculosis with next generation benzothiazinones

scientific article

Towards a new tuberculosis drug: pyridomycin - nature's isoniazid

scientific article

Towards an immunodiagnostic test for leprosy

scientific article published on 26 May 2006

Transcription facilitated genome-wide recruitment of topoisomerase I and DNA gyrase

scientific article

Transmission of Drug-Resistant Leprosy in Guinea-Conakry Detected Using Molecular Epidemiological Approaches.

scientific article published on 23 August 2016

TubercuList--10 years after

scientific article published on October 25, 2010

Tuberculosis biomarkers discovery: developments, needs, and challenges

scientific article published on 24 March 2013

Tuberculosis drug discovery in the post-post-genomic era

scientific article

Tuberculosis drug discovery needs public–private consortia

scientific article published on 04 October 2016

Tuberculosis: from genome to vaccine

scientific article

Use of consensus sequences for the design of high density resequencing microarrays: the influenza virus paradigm

scientific article

Virulence regulator EspR of Mycobacterium tuberculosis is a nucleoid-associated protein.

scientific article

Whole cell screen based identification of spiropiperidines with potent antitubercular properties

scientific article published on 03 June 2015

Whole genome sequencing distinguishes between relapse and reinfection in recurrent leprosy cases

scientific article

Zoonotic Leprosy in the Southeastern United States

scientific article

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