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List of works by Steven J. Burakoff

54 Use of the HLA-DR antigens incorporated into liposomes to generate HLA-DR specific cytotoxic T lymphocytes

scientific article published on 01 January 1984

A CD8/Lck transgene is able to drive thymocyte differentiation

scientific article

A DC-specific cytolytic T lymphocyte line is OKT8+1

scientific article published on 01 December 1983

A Remembrance of Baruj Benacerraf (AAI '57) 1920–2011 ⬇️

scientific article published on December 1, 2011

A comparative analysis of the phosphoinositide binding specificity of pleckstrin homology domains

scientific article

A distinct cytoplasmic domain of CD2 regulates ligand avidity and T-cell responsiveness to antigen

scientific article published on August 1992

A large proportion of T lymphocytes lack CD5 expression after bone marrow transplantation.

scientific article published in April 1989

A molecular analysis of the cytolytic T lymphocyte response

scientific article

A monoclonal antibody to LFA-3, the CD2 ligand, specifically immobilizes major histocompatibility complex proteins

scientific article published on 01 April 1989

A peptide library approach identifies a specific inhibitor for the ZAP-70 protein tyrosine kinase

scientific article

A perspective on HPK1 as a novel immuno-oncology drug target

scientific article published on 08 September 2020

A role for calcineurin in degranulation of murine cytotoxic T lymphocytes ⬇️

scientific article published on 01 April 1993

Abnormal cytolytic activity of lymphocyte function-associated antigen-1-deficient human cytolytic T lymphocyte clones.

scientific article

Absence of mitochondrial superoxide dismutase results in a murine hemolytic anemia responsive to therapy with a catalytic antioxidant

scientific article

Acute cutaneous graft-versus-host disease to minor histocompatibility antigens in a murine model. Evidence that large granular lymphocytes are effector cells in the immune response

scientific article published on 01 July 1986

Acute graft-versus-host disease: pathogenesis and prevention with a monoclonal antibody in vivo

scientific article published on 01 February 1987

Adapting to multiple personalities: Cbl is also a RING finger ubiquitin ligase

scientific article

Adhesion of T lymphocytes to human endothelial cells is regulated by the LFA-1 membrane molecule

scientific article published on 01 February 1986

Adhesion receptors in lymphocyte activation.

scientific article published on June 1994

Alkylating HIV-1 Nef - a potential way of HIV intervention

scientific article published on 26 July 2010

Alloreactive lymphocytes from T cell receptor (beta-chain) transgenic mice do not mediate a graft-versus-host reaction

scientific article

Alloreactivity studied with mutants of HLA-A2.

scientific article

Allospecific and virus-specific cytolytic T lymphocytes are restricted to the N or C1 domain of H-2 antigens expressed on L cells after DNA-mediated gene transfer.

scientific article published on May 1983

Alpha and beta subunits of the LFA-1 membrane molecule are involved in human monocyte-endothelial cell adhesion

scientific article published on 01 March 1987

Alpha particle radio-immunotherapy: animal models and clinical prospects

scientific article published on 01 June 1989

Amelioration of acute graft vs host disease due to minor histocompatibility antigens by in vivo administration of anti-interleukin 2 receptor antibody

scientific article published on 01 September 1986

Analysis of CD4 and CD2 receptor function

scientific article published on 01 January 1988

Analysis of cross-reactive antigen-specific T cell clones. Specific recognition of two major histocompatibility complex (MHC) and two non-MHC antigens by a single clone ⬇️

scientific article published on June 1, 1983

Analysis of the two-signal requirement for precursor cytolytic T lymphocyte activation using H-2Kk in liposomes

scientific article published on 01 May 1982

Antigen-induced unresponsiveness results in altered T cell signaling

scientific article published on 01 December 1999

Antigen-presenting cell function in induction of helper T cells for cytotoxic T-lymphocyte responses: evidence for antigen processing

scientific article

Antigen-specific suppression of cytotoxic T cell responses: an idiotype-bearing factor regulates the cytotoxic T cell response to azobenzenearsonate-coupled cells ⬇️

scientific article published on 01 March 1982

B cell stimulatory factor-2 is involved in the differentiation of cytotoxic T lymphocytes

scientific article published on 01 January 1988

Basic science seminar: cytotoxic T-lymphocyte response to HLA antigens

scientific article published on 01 June 1983

Binding affinities of tyrosine-phosphorylated peptides to the COOH-terminal SH2 and NH2-terminal phosphotyrosine binding domains of Shc

scientific article published on 01 December 1995

Biochemical and functional analyses of a secreted H-2Ld molecule

scientific article published on April 1986

Biodistribution studies of anti-Thy 1.2 IgM immunoconjugates: Implications for radioimmunotherapy ⬇️

scientific article published on 01 August 1988

Biological significance of alloreactivity: T cells stimulated by Sendai virus-coated syngeneic cells specifically lyse allogeneic target cells ⬇️

scientific article published on October 1, 1978

Bone marrow transplantation: the genetic and cellular basis of resistance to engraftment and acute graft-versus-host disease

scientific article

CD4 and signal transduction.

scientific article

CD4 phosphorylation partially reverses Nef down-regulation of CD4.

scientific article

CD4, CD8 and CD2 in T cell adhesion and signaling.

scientific article published on January 1993

CD43 regulates the threshold for T cell activation by targeting Cbl functions ⬇️

scientific article published on September 9, 2011

CD43, a molecule defective in Wiskott-Aldrich syndrome, binds ICAM-1 ⬇️

scientific article published on November 21, 1991

CD43-mediated signals induce DNA binding activity of AP-1, NF-AT, and NFkappa B transcription factors in human T lymphocytes

scientific article (publication date: 6 October 2000)

CD43-specific activation of T cells induces association of CD43 to Fyn kinase

scientific article

CD8 beta chain influences CD8 alpha chain-associated Lck kinase activity

scientific article

CPF-DD is an inhibitor of infection by human immunodeficiency virus and other enveloped viruses in vitro ⬇️

scientific article (publication date: June 1992)

CTL adhesion and antigen recognition are discrete steps in the human CTL-target cell interaction

scientific article published on 01 March 1987

Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A ⬇️

scientific article (publication date: May 1992)

Calcineurin regulation of the mammalian G0/G1 checkpoint element, cyclin dependent kinase 4.

scientific article

Cancer therapy from bench to bedside

scientific article published on 01 November 2010

Cell-mediated cytotoxicity. An overview

scientific article published on 01 February 1984

Cell-mediated immunity to viral glycoproteins.

scientific article published on January 1980

Cellular interactions in the generation of cytolytic T lymphocyte responses. Analysis of the helper T cell pathway

scientific article published on 01 May 1981

Cellular interactions in the generation of cytolytic T lymphocyte responses: role of Ia-positive splenic adherent cells in presentation in H-2 antigen

scientific article

Cellular interactions in the regulation of the cytolytic T-lymphocyte response: the effect of suboptimal antigen dose

scientific article published on 01 March 1981

Characterization of a mutant calcineurin A alpha gene expressed by EL4 lymphoma cells

scientific article published on July 1995

Cloning of p97/Gab2, the major SHP2-binding protein in hematopoietic cells, reveals a novel pathway for cytokine-induced gene activation

scientific journal article

Coexpression of the human HLA-A2 or HLA-B7 heavy chain gene and human beta 2-microglobulin gene in L cells

scientific article published on 01 December 1984

Constitutive activation of the Janus kinase-STAT pathway in T lymphoma overexpressing the Lck protein tyrosine kinase ⬇️

scientific article published on December 1, 1997

Construction, expression and recognition of an H—2 molecule lacking its carboxyl terminus

scientific article published in Nature

Coreceptors and adapter proteins in T-cell signaling

scientific article published on September 1995

Correlation of calcineurin phosphatase activity and programmed cell death in murine T cell hybridomas

scientific article published in October 1992

Crk interacts with tyrosine-phosphorylated p116 upon T cell activation

scientific article

Cross-reactive lysis of trinitrophenyl (TNP)-derivatized H-2 incompatible target cells by cytolytic T lymphocytes generated against syngeneic TNP spleen cells ⬇️

scientific article published on December 1, 1976

Cutaneous acute graft-versus-host disease to minor histocompatibility antigens in a murine model: histologic analysis and correlation to clinical disease

scientific article

Cutting edge: gab2 mediates an inhibitory phosphatidylinositol 3'-kinase pathway in T cell antigen receptor signaling

scientific article published on 01 October 2000

Cyclosporin A and FK506: molecular mechanisms of immunosuppression and probes for transplantation biology.

scientific article

Cytolytic T lymphocyte recognition of subcellular antigen

scientific article published on 01 January 1982

Cytolytic T lymphocyte response to Moloney sarcoma virus

scientific article published in January 1983

Cytolytic pathways in haematopoietic stem-cell transplantation

scientific article

Cytosolic tyrosine dephosphorylation of STAT5. Potential role of SHP-2 in STAT5 regulation

scientific article (publication date: 7 January 2000)

Cytotoxic T cells directed against HLA-DR antigens and their surface proteins.

scientific article

Cytotoxic T lymphocyte recognition of class I H-2 antigens after DNA-mediated gene transfer.

scientific article published in February 1984

Cytotoxic T lymphocyte recognition of transfected cells expressing a cloned retroviral gene

scientific article published on October 1983

Cytotoxic T lymphocytes induced against allogeneic I-region determinants react with Ia molecules on trinitrophenyl-conjugated syngeneic target cells ⬇️

scientific article published on August 1, 1977

Cytotoxic T lymphocytes specific for I region determinants do not require interactions with H-2K or D gene products

scientific article

Determination of junction avidity of cytolytic T cell and target cell

scientific article published in December 1986

Development and characterization of allospecific long-term human cytolytic T-cell lines

scientific article

Developmental control point in induction of thymic cortex regulated by a subpopulation of prothymocytes

scientific article published in January 1995

Differential activation of phosphotyrosine protein phosphatase activity in a murine T cell hybridoma by monoclonal antibodies to CD45 ⬇️

scientific article published on March 25, 1992

Differential use of Fas ligand and perforin cytotoxic pathways by donor T cells in graft-versus-host disease and graft-versus-leukemia effect

scientific article published on 01 May 2001

Direct evidence for a receptor-ligand interaction between the T-cell surface antigen CD2 and lymphocyte-function-associated antigen 3.

scientific article

Direct evidence for binding of CD8 to HLA class I antigens

scientific article

Disruption of T cell development and repertoire selection by calcineurin inhibition in vivo.

scientific article published in November 1994

Disruption of the CD4-p56lck complex is required for rapid internalization of CD4 ⬇️

scientific article published on August 15, 1992

Dissection of immune gene networks in primary melanoma tumors critical for antitumor surveillance of patients with stage II-III resectable disease

scientific article published on 12 February 2014

Dissection of serological and cytolytic T lymphocyte epitopes on murine major histocompatibility antigens by a recombinant H-2 gene separating the first two external domains

scientific article

Distinct effects of interferon-gamma and MHC class I surface antigen levels on resistance of the K562 tumor cell line to natural killer-mediated lysis

scientific article published on October 1990

Distinct roles for L3T4 in T cell activation.

scientific article published on February 1987

Dynamic changes in viscoelastic properties in cytotoxic T-lymphocyte-mediated killing

scientific article published on 01 October 1988

Effect of anti-IL-2Ralpha antibody on IL-2-induced Jak/STAT signaling

scientific article published in January 2002

Effect of timing of lymphokine presentation on generation of cytotoxic T lymphocytes

scientific article published on 01 January 1989

Efficient conjugation of DTPA to an IgM monoclonal antibody in ascites fluid

scientific article published on 01 January 1988

Engraftment following T cell-depleted bone marrow transplantation. III. Differential effects of increased total-body irradiation on semiallogeneic and allogeneic recipients

scientific article published on 01 May 1988

Engraftment following T-cell-depleted bone marrow transplantation. II. Stability of mixed chimerism in semiallogeneic recipients after total-body irradiation

scientific article published on 01 October 1987

Engraftment following T-cell-depleted marrow transplantation. I. The role of major and minor histocompatibility barriers

scientific article published on 01 April 1987

Enhanced allostimulatory activity of host antigen-presenting cells in old mice intensifies acute graft-versus-host disease

scientific article

Enhancement of T-cell activation by the CD43 molecule whose expression is defective in Wiskott-Aldrich syndrome

scientific article

Evidence for a Requirement for Both Phospholipid and Phosphotyrosine Binding via the Shc Phosphotyrosine-Binding Domain In Vivo ⬇️

scientific article published on September 1, 1997

Evidence for a physical association between the Shc-PTB domain and the beta c chain of the granulocyte-macrophage colony-stimulating factor receptor

scientific journal article

Evidence for a role for the phosphotyrosine-binding domain of Shc in interleukin 2 signaling

scientific article

Evidence for differential intracellular signaling via CD4 and CD8 molecules

scientific article

Evidence that anti-LFA-1 in vivo improves engraftment and survival after allogeneic bone marrow transplantation

scientific article published on 01 May 1990

Evidence that anti-asialo GM1 in vivo improves engraftment of T cell-depleted bone marrow in hybrid recipients.

scientific article published on January 1990

Evidence that large granular lymphocytes of donor origin mediate acute graft-versus-host disease

scientific article published on 01 January 1989

Experimental evidence for the potential usefulness of permanent IL-3-dependent multipotential hematopoietic progenitor cell lines in transfusion granulocyte support therapy: need for expansion of early passage cells

scientific article published on 01 January 1984

Expression and CTL recognition of cloned subgenomic fragments of Moloney murine leukemia virus in murine cells

scientific article published in January 1985

Expression and function of CD4 in a murine T-cell hybridoma

scientific article published in Nature

Expression and function of CD8 in a murine T cell hybridoma

scientific article

Expression and function of a CD 5 cDNA in human and murine T cells

article

Expression and induction of nuclear factor-kappa B-related proteins in thymocytes

scientific article published in April 1995

Expression and ontogeny of CD2 on murine B cells.

scientific article published in April 1990

Expression and ontogeny of murine CD2

scientific article published on 01 July 1989

Expression of CD5 regulates responsiveness to IL-1.

scientific article published in November 1988

Expression of the T-cell surface molecule CD2 and an epitope-loss CD2 mutant to define the role of lymphocyte function-associated antigen 3 (LFA-3) in T-cell activation

scientific article

Expression of the T-cell-specific gamma gene is unnecessary in T cells recognizing class II MHC determinants

scientific article

FK 506 and rapamycin: molecular probes of T-lymphocyte activation

scientific article published on December 1, 1991

FK506 binding protein 12 mediates sensitivity to both FK506 and rapamycin in murine mast cells

scientific article published on February 1995

FK506 inhibits antigen receptor-mediated induction of c-rel in B and T lymphoid cells

scientific article

Fas ligand-deficient gld mice are more susceptible to graft-versus-host-disease

scientific article published on 01 July 2000

Fas-deficient lpr mice are more susceptible to graft-versus-host disease

scientific article published on 01 January 2000

Fratricide of CD8+ cytotoxic T lymphocytes is dependent on cellular activation and perforin-mediated killing

scientific article

From bytes to bedside: data integration and computational biology for translational cancer research

scientific article

Functional CD2 mutants unable to bind to, or be stimulated by, LFA-3 ⬇️

scientific article published on February 15, 1990

Functional T cell deficits after bone marrow transplantation across minor histocompatibility barriers: effects of graft-vs-host disease on precursor frequency of reactive cells

scientific article published on 01 June 1987

Functional analysis of CD2, CD4, and CD8 in T-cell activation

scientific article published on January 1988

Functional analysis of a cytoplasmic domain-deleted mutant of the CD4 molecule

scientific article published on 01 July 1988

Functional assessment of T cell depletion from bone marrow prior to therapeutic transplantation using limiting dilution culture methods

scientific article published on 01 October 1986

Functional distinctions between the LFA-1, LFA-2, and LFA-3 membrane proteins on human CTL are revealed with trypsin-pretreated target cells.

scientific article published on January 1985

Functional expression of human CD8 in fully reconstituted mice after retroviral-mediated gene transfer of hemopoietic stem cells ⬇️

scientific article published on July 15, 1992

Gene mapping and somatic cell hybrid analysis of the role of human lymphocyte function-associated antigen-3 (LFA-3) in CTL-target cell interactions

scientific article

Generation of cytolytic T lymphocytes after reovirus infection: role of S1 gene ⬇️

scientific article published on January 1, 1979

Generation of cytolytic T lymphocytes in thymectomized, irradiated, and bone marrow-reconstituted mice

scientific article published on September 1982

Generation of long-term human cytolytic cell lines with persistent natural killer activity.

scientific article published in October 1982

Genetic control of cytolytic T lymphocyte responses. III. The role of K and I region alleles on the specificity of the cytolytic T lymphocyte response to trinitrophenyl-modified syngeneic cells

scientific article published on 01 October 1980

Genetic control of cytolytic T-lymphocyte responses. I. Ir gene control of the specificity of cytolytic T-lymphocyte responses to trinitrophenyl-modified syngeneic cells ⬇️

scientific article published on August 1, 1978

Genetic control of cytolytic t-lymphocyte responses. II. The role of the host genotype in parental leads to F1 radiation chimeras in the control of the specificity of cytolytic T-lymphocyte responses to trinitrophenyl-modified syngeneic cells ⬇️

scientific article published on August 1, 1978

Genetic control of the cytolytic T lymphocyte response to influenza viruses: H-2 genes influence the response to H-2Kb plus virus ⬇️

scientific article published on May 1, 1982

Glycolipid-anchored form of CD4 increases intercellular adhesion but is unable to enhance T cell activation ⬇️

scientific article published on July 15, 1991

Glycoproteins of 210,000 and 130,000 m.w. on activated T cells: cell distribution and antigenic relation to components on resting cells and T cell lines ⬇️

scientific article published on June 1, 1984

Graft-versus-host-disease-associated thymic damage results in the appearance of T cell clones with anti-host reactivity

scientific article published on 01 February 2000

Growth-inhibitory activity of lymphoid cell plasma membranes. II. Partial characterization of the inhibitor ⬇️

scientific article published on October 1, 1984

H-2Ld antigen encoded by a recombinant retrovirus genome is expressed on the surface of infected cells

scientific article published on June 1985

HIV Nef-mediated CD4 down-regulation is adaptor protein complex 2 dependent

scientific article

HIV-gp120 can block CD4-class II MHC-mediated adhesion

scientific article

HPK1 Influences Regulatory T Cell Functions

scientific article published on 06 July 2020

HPK1 as a novel target for cancer immunotherapy ⬇️

scientific article published on December 1, 2012

Hematopoietic progenitor kinase 1 (HPK1) negatively regulates prostaglandin E2-induced fos gene transcription

scientific article

Hematopoietic progenitor kinase 1 is a critical component of prostaglandin E2-mediated suppression of the anti-tumor immune response

scientific article published on 29 September 2009

Hematopoietic progenitor kinase 1 is a negative regulator of dendritic cell activation

scientific article published in May 2009

Heritable lymphocyte function-associated antigen-1 deficiency: abnormalities of cytotoxicity and proliferation associated with abnormal expression of LFA-1

scientific article published on 01 November 1985

Human 70-kDa SHP-1L differs from 68-kDa SHP-1 in its C-terminal structure and catalytic activity

scientific article

Human cytolytic T lymphocyte interactions with vascular endothelium and fibroblasts: role of effector and target cell molecules

scientific article published on 01 October 1984

Human dermal fibroblasts present tetanus toxoid antigen to antigen-specific T cell clones

scientific article

Human immunodeficiency virus infection is efficiently mediated by a glycolipid-anchored form of CD4.

scientific article

Human lymphocyte function associated antigen-1 (LFA-1): identification of multiple antigenic epitopes and their relationship to CTL-mediated cytotoxicity ⬇️

scientific article published on September 1, 1983

Human lymphocyte function associated antigens ⬇️

scientific article published on January 1, 1984

Ia expression by vascular endothelium is inducible by activated T cells and by human gamma interferon

scientific article

Identification and structural analysis of residues in the V1 region of CD4 involved in interaction with human immunodeficiency virus envelope glycoprotein gp120 and class II major histocompatibility complex molecules

scientific article

Identification of a novel binding site between HIV type 1 Nef C-terminal flexible loop and AP2 required for Nef-mediated CD4 downregulation

scientific article published on 31 December 2012

Identification of a physical interaction between calcineurin and nuclear factor of activated T cells (NFATp)

scientific journal article

Immunochemically purified DR antigens in liposomes stimulate xenogeneic cytolytic T cells in secondary in vitro cultures

scientific article published on 01 November 1986

Immunodeficiency in graft-versus-host disease. I. Mechanism of immune suppression

scientific article published on 01 May 1988

Immunophilins in protein folding and immunosuppression.

scientific article

In vitro generation of helper T cells and suppressor T cells that regulate the cytolytic T lymphocyte response to trinitrophenyl-modified syngeneic cells

scientific article published on 01 April 1982

Increasing T-cell age reduces effector activity but preserves proliferative capacity in a murine allogeneic major histocompatibility complex-mismatched bone marrow transplant model

scientific article

Induction of HLA class I surface expression recruits low-affinity cytolytic T lymphocytes

scientific article published on 01 January 1990

Induction of alloantigen-specific tolerance by B cells from CD40-deficient mice

scientific article published on May 1996

Induction of allogeneic cytolytic T lymphocytes by partially purified membrane glycoproteins

scientific article published on 01 April 1980

Induction of secondary cytotoxic T lymphocytes by liposomes containing HLA-DR antigens.

scientific article published in January 1980

Induction of secondary cytotoxic T lymphocytes by purified HLA-A and HLA-B antigens reconstituted into phospholipid vesicles ⬇️

scientific article published on November 1, 1978

Inhibition of CD4+ T cell function by the HIV envelope protein, gp120

scientific article

Inhibition of cell-mediated cytolysis of trinitrophenyl-derivatized target cells by alloantisera directed to the products of the K and D loci of the H-2 complex ⬇️

scientific article published on February 1, 1976

Inhibition of interleukin-1 by an interleukin-1 receptor antagonist prevents graft-versus-host disease

scientific article published on 01 October 1991

Inhibition of lymphokine-activated killer cell-mediated cytotoxicity by phorbol ester

scientific article published in March 1989

Inhibition of normal lymphocyte responses by cell membranes ⬇️

scientific article published on 01 November 1984

Inhibition of the induction of cytolytic T lymphocytes with alloantisera directed against H-2K and H-2D gene products ⬇️

scientific article published on May 1, 1978

Interaction of CD2 with its ligand lymphocyte function-associated antigen-3 induces adenosine 3',5'-cyclic monophosphate production in T lymphocytes ⬇️

scientific article published on 01 July 1991

Interaction of CD2 with its ligand, LFA-3, in human T cell proliferation

scientific article published on 01 May 1988

Interaction of Shc with Grb2 regulates association of Grb2 with mSOS

scientific journal article

Interaction of Shc with Grb2 regulates the Grb2 association with mSOS

scientific article published on 01 September 1995

Interaction of Shc with the zeta chain of the T cell receptor upon T cell activation

scientific article published on November 1993

Interactions of T lymphocytes with human vascular endothelial cells: role of endothelial cells surface antigens.

scientific article published on December 1984

Interferon-gamma induction of LFA-1-mediated homotypic adhesion of human monocytes

scientific article published on 01 July 1986

Interleukin-3 (IL-3)-induced c-fos activation is modulated by Gab2-calcineurin interaction

scientific article

Interruption of the sequential release of small and large molecules from tumor cells by low temperature during cytolysis mediated by immune T-cells or complement

scientific article published on January 1974

Intracellular signaling consequences of anti-IL-2Ralpha blockade by daclizumab

scientific article published on February 2001

Intrathymic signals in thymocytes are mediated by p38 mitogen-activated protein kinase.

scientific article published in June 1996

Involvement of proteasomes in regulating Jak-STAT pathways upon interleukin-2 stimulation.

scientific article published on May 1997

Ir gene control of the cytotoxic T lymphocyte response to Sendai virus: H-2k mice are low responders to Sendai ⬇️

scientific article published on December 1, 1981

Irradiated B7-1 transduced primary acute myelogenous leukemia (AML) cells can be used as therapeutic vaccines in murine AML

scientific article published on 01 April 1996

Is the primary complement lesion insufficient for lysis? Failure of cells damaged under osmotic protection to lyse in EDTA or at low temperature after removal of osmotic protection

scientific article published in May 1975

LFA-1 membrane molecule in the regulation of homotypic adhesions of human B lymphocytes

scientific article published on 01 July 1985

LFA-1, LFA-2, and LFA-3 antigens are involved in CTL-target conjugation.

scientific article

Lack of SHPTP1 results in src-family kinase hyperactivation and thymocyte hyperresponsiveness

scientific article

Lateral mobility of class I histocompatibility antigens in B lymphoblastoid cell membranes: modulation by cross-linking and effect of cell density

scientific article

Lck-dependent tyrosyl phosphorylation of the phosphotyrosine phosphatase SH-PTP1 in murine T cells

scientific article

Lipid raft distribution of CD4 depends on its palmitoylation and association with Lck, and evidence for CD4-induced lipid raft aggregation as an additional mechanism to enhance CD3 signaling

scientific article

Localization of the FK506-binding protein, FKBP 13, to the lumen of the endoplasmic reticulum

scientific article

Long-lasting deficit of functional T cell precursors in human bone marrow transplant recipients revealed by limiting dilution methods

scientific article published on 01 June 1986

Long-term human cytolytic T-cell lines allospecific for HLA-DR6 antigen are OKT4+.

scientific article

Loss of normal thymic repertoire selection and persistence of autoreactive T cells in graft vs host disease

scientific article published in February 1994

Lymphocytes recognize human vascular endothelial and dermal fibroblast Ia antigens induced by recombinant immune interferon

scientific article published in Nature

Lymphocytes with a CD4+ CD8- CD3- phenotype are effectors of experimental cutaneous graft-versus-host disease ⬇️

scientific article published on December 1, 1991

Lymphoid irradiation results in long-term increases in natural killer cells in patients treated for Hodgkin's disease ⬇️

scientific article published on February 1, 1992

Lysine 144, a ubiquitin attachment site in HIV-1 Nef, is required for Nef-mediated CD4 down-regulation

scientific article

Major histocompatibility complex products restrict the adherence of cytolytic T lymphocytes to minor histocompatibility antigens or to trinitrophenyl determinants on schistosomula of Schistosoma mansoni ⬇️

scientific article published on April 1, 1979

Mapping functional epitopes of the human LFA-1 glycoprotein: monoclonal antibody inhibition of NK and CTL effectors

scientific article published on 01 November 1986

Measurement of Calcineurin Phosphatase Activity in Cell Extracts

scientific article published on 01 April 1996

Mechanisms of immunosuppression by FK506. Preservation of T cell transmembrane signal transduction

scientific article published on June 1, 1990

Membrane-bound anti-CD3 monoclonal antibodies trigger cytolytic T-lymphocyte-mediated tumor lysis

scientific article published on 01 October 1988

Molecular and biological actions of cyclosporin A and FK506 on T cell development and function

scientific article

Molecular cloning of a 25-kDa high affinity rapamycin binding protein, FKBP25 ⬇️

scientific article published on June 5, 1992

Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13

scientific article

Monoallelic Expression of the Interleukin-2 Locus ⬇️

scientific article published on March 27, 1998

Mouse cytolytic T lymphocytes induced by xenogeneic rat stimulator cells exhibit specificity for H-2 complex alloantigens

scientific article

Multiple conformational states of the HPK1 kinase domain in complex with sunitinib reveal the structural changes accompanying HPK1 trans-regulation

scientific article published on 24 April 2019

Murine CD2: structure, expression, and recognition of human LFA-3.

scientific article published on January 1989

Mutants of HLA-A2 in the analysis of its structure and function

scientific article published on January 1989

NFATc2-mediated repression of cyclin-dependent kinase 4 expression

scientific journal article

Natural killer cell development is blocked in the context of aberrant T lymphocyte ontogeny

scientific article published on 01 June 1996

Nicotine activates nuclear factor of activated T cells c2 (NFATc2) and prevents cell cycle entry in T cells

scientific article

Non-MHC-restricted target-cell lysis by a CD4-CD8- TCR alpha beta T-cell line, as well as by TCR gamma delta T-cell lines, results from lymphokine-activated killing

scientific article published on April 1991

Non-MHC-restricted target-cell lysis by a CD4−CD− TCRαβ T-cell line, as well as by TCR4gMδ T-cell lines, results from lymphokine-activated killing

Non-invasive in vivo imaging for liver tumour progression using an orthotopic hepatocellular carcinoma model in immunocompetent mice

scientific article published on 11 April 2011

Novel subsets of human T cells (CD4+ CD8+ TCRγδ and CD4− CD8− TCRαβ) and T-cell development

Novel subsets of human T cells (CD4+ CD8- TCR gamma delta and CD4- CD8- TCR alpha beta) and T-cell development

scientific article published on January 1989

Nuclear factors that mediate intrathymic signals are developmentally regulated

scientific article

Partial deletions of the cytoplasmic domain of CD2 result in a partial defect in signal transduction

scientific article published on 01 February 1990

Phenotypic and functional analysis of expanded natural killer cell subpopulations in Hodgkin's disease patients treated with lymphoid irradiation

scientific article published on 01 July 1993

Phenotypic and functional characterization of human cytolytic T cells lacking expression of CD5.

scientific article published on May 1988

Phytohaemagglutinin activation of T cells through the sheep red blood cell receptor

scientific article published in Nature

Positive and negative signaling pathways

scientific article

Prevention of HIV-1 infection and preservation of CD4 function by the binding of CPFs to gp120.

scientific article published on July 1990

Probing Immunosuppressant Action with a Nonnatural Immunophilin Ligand ⬇️

scientific article published on October 26, 1990

Production of colony-stimulating factor(s) for granulocyte-macrophage and multipotential (granulocyte/erythroid/megakaryocyte/macrophage) hematopoietic progenitor cells (CFU-GEMM) by clonal lines of human IL-2-dependent T-lymphocytes

scientific article published on 01 October 1984

Prostaglandin E2 activates HPK1 kinase activity via a PKA-dependent pathway

scientific article

Protein kinase C required for cytotoxic T lymphocyte triggering

scientific article published on 01 November 1987

Radioimmunotherapy with alpha-particle-emitting immunoconjugates

scientific article published on 01 May 1988

Rapamycin and FK506 binding proteins (immunophilins)

article

Rapamycin-resistant proliferation of CD8+ T cells correlates with p27kip1 down-regulation and bcl-xL induction, and is prevented by an inhibitor of phosphoinositide 3-kinase activity

scientific article

Recapitulation of the immune response and haematopoietic system in bone marrow transplantation

scientific article published on October 1983

Recognition of HLA-A2 and -B7 antigens by cloned cytotoxic T lymphocytes after gene transfer into human and monkey, but not mouse, cells

scientific article published on December 1984

Recognition of HLA-A2 mutant and variant target cells by an HLA-A2 allospecific human cytotoxic T lymphocyte line ⬇️

scientific article published on September 1, 1983

Recognition of interspecies hybrid class I histocompatibility antigens by antigen-specific cytolytic T lymphocytes

scientific article published on September 1985

Recognition of the alpha-1 and alpha-2 domains of H-2 molecules by allospecific cloned T cells

Regulation of Cbl molecular interactions by the co-receptor molecule CD43 in human T cells

scientific article (publication date: 5 January 2001)

Regulation of cytotoxic T lymphocyte-mediated graft rejection following bone marrow transplantation.

scientific article published in December 1988

Regulation of tyrosine phosphorylation in isolated T cell membrane by inhibition of protein tyrosine phosphatases ⬇️

scientific article published on August 15, 1998

Requirement for Shc in TCR-mediated activation of a T cell hybridoma

scientific article published on September 1999

Requirement for three distinct lymphokines for the induction of cytotoxic T lymphocytes from thymocytes

scientific article published on 01 December 1986

Requirements for modulation of the CD4 molecule in response to phorbol myristate acetate. Role of the cytoplasmic domain

scientific article published on 01 March 1989

Responses to the H–2Kba mutant involve recognition of syngeneic Ia molecules ⬇️

scientific article published on 01 March 1983

Retarded recovery of functional T cell frequencies in T cell-depleted bone marrow transplant recipients

scientific article published on 01 October 1987

Retrovirus-induced changes in major histocompatibility complex antigen expression influence susceptibility to lysis by cytotoxic T lymphocytes

scientific article published in October 1985

Role of L3T4 in antigen-driven activation of a class I-specific T cell hybridoma

scientific article

Role of syngeneic Ia+ accessory cells in the generation of allospecific CTL responses

scientific article published on 01 August 1982

Role of the Lck Src homology 2 and 3 domains in protein tyrosine phosphorylation

scientific article

SLAP, a dimeric adapter protein, plays a functional role in T cell receptor signaling

scientific article

SOD2-deficiency anemia: protein oxidation and altered protein expression reveal targets of damage, stress response, and antioxidant responsiveness

scientific journal article

Severe colitis in mice with aberrant thymic selection

scientific article published on 01 July 1995

Sialophorin, a surface sialoglycoprotein defective in the Wiskott-Aldrich syndrome, is involved in human T lymphocyte proliferation

scientific article

Signal transduction pathways involved in T cell receptor-induced regulation of CD2 avidity for CD58 ⬇️

scientific article published on 01 April 1993

Signaling T-cell survival and death by IL-2 and IL-15.

scientific article published on November 2005

Site-directed mutagenesis of class I HLA genes. Role of glycosylation in surface expression and functional recognition

scientific article

Solution structure of the Shc SH2 domain complexed with a tyrosine-phosphorylated peptide from the T-cell receptor

scientific article

Species-restricted recognition of transfected HLA-A2 and HLA-B7 by human CTL clones

Specificity of OKT4+ cytotoxic T lymphocyte clones

scientific article published on 01 November 1982

Specificity of alloreactive T lymphocytes that adhere to lung stage schistosomula of Schistosoma mansoni

scientific article published on 01 May 1980

Specificity of mouse cytotoxic T lymphocytes stimulated with either HLA-A and -B or HLA-DR antigens reconstituted into phospholipid vesicles

scientific article published on 01 August 1980

Specificity of rat xenogeneic cell-mediated cytolysis for the products of the K and D loci of the mouse H-2 complex ⬇️

scientific article published on May 1, 1977

Specificity of the helper T cell for the cytolytic T lymphocyte response to influenza viruses.

scientific article

Spontaneous aggregation as a mechanism for human monocyte purification

scientific article published on 01 September 1986

Stimulation of secondary anti-MSV cytolytic T lymphocytes with MBL-2 reconstituted membranes

scientific article published in January 1983

Structural organization of the genes encoding human and murine FK506-binding protein (FKBP) 13 and comparison to FKBP1.

scientific article

Structure and ligand recognition of the phosphotyrosine binding domain of Shc

scientific article

Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase

scientific article

Suppression of anti-hapten antibody responses by hapten-specific cytolytic T lymphocytes: role of I-A-associated antigen on target B lymphocytes ⬇️

scientific article published on 01 July 1982

Synergistic T cell activation via the physiological ligands for CD2 and the T cell receptor

scientific article

T Cell Activation through the CD43 Molecule Leads to Vav Tyrosine Phosphorylation and Mitogen-activated Protein Kinase Pathway Activation ⬇️

scientific article published on June 5, 1998

T cell adhesion molecules

scientific article published on July 1988

T cell hybridomas define the class II MHC-restricted response to vesicular stomatitis virus infection

scientific article

T cell receptors: adhesion and signaling

scientific article published on January 1991

T cell surface molecules regulating noncognate B lymphocyte activation. Role of CD2 and LFA-1.

scientific article published on February 1992

T lymphocyte-mediated suppression of myeloma function in vitro. II. Evidence for regulation of hapten-binding myelomas by syngeneic hapten-specific cytolytic T lymphocytes ⬇️

scientific article published on August 1, 1980

T lymphocyte-mediated suppression of myeloma function in vitro. III. Regulation of antibody production in hybrid myeloma cells by T lymphocytes ⬇️

scientific article published on October 1, 1980

T-cell receptor-CD4 physical association in a murine T-cell hybridoma: induction by antigen receptor ligation

scientific article

T-lymphocyte activation: the biology and function of CD2 and CD4.

scientific article published on October 1989

T3 monoclonal antibody activation of nonspecific cytolysis: a mechanism of CTL inhibition

scientific article published on 01 July 1985

Targeting Src homology 2 domain-containing tyrosine phosphatase (SHP-1) into lipid rafts inhibits CD3-induced T cell activation

scientific article

The 25-kDa FK506-binding protein is localized in the nucleus and associates with casein kinase II and nucleolin ⬇️

scientific article published on August 15, 1993

The CD4 molecule is not always required for the T cell response to bacterial enterotoxins

scientific article

The Small GTP-Binding Protein Rho Potentiates AP-1 Transcription in T Cells ⬇️

scientific article published on September 1, 1998

The Structure of HPK1 Kinase Domain: To Boldly Go Where No Immuno-Oncology Drugs Have Gone Before

scientific article published on 01 January 2019

The ability of Ia and H-2Kk-bearing membranes to replace the antigen-presenting cell in an H-2Kk allogeneic cytotoxic T cell response

scientific article published on 01 October 1985

The adapter protein Shc interacts with the interleukin-2 (IL-2) receptor upon IL-2 stimulation

scientific article

The alpha-3 domain of class I MHC proteins influences cytotoxic T lymphocyte recognition of antigenic determinants located within the alpha-1 and alpha-2 domains

scientific article published in June 1988

The biologic roles of CD2, CD4, and CD8 in T-cell activation

scientific article published on January 1989

The biologic significance of alloreactivity. The ontogeny of T-cell sets specific for alloantigens or modified self antigens ⬇️

scientific article published on November 1, 1978

The complex of FK506-binding protein 12 and FK506 inhibits calcineurin phosphatase activity and IgE activation-induced cytokine transcripts, but not exocytosis, in mouse mast cells.

scientific article published on February 1995

The cytolytic T lymphocyte response to trinitrophenyl-modified syngeneic cells. I. Evidence for antigen-specific helper T cells ⬇️

scientific article published on September 1, 1979

The cytolytic T lymphocyte response to trinitrophenyl-modified syngeneic cells. II. Evidence for antigen-specific suppressor T cells ⬇️

scientific article published on September 1, 1979

The cytoplasmic domain of CD4 is required for stable association with the lymphocyte-specific tyrosine protein kinase p56lck

scientific article published on June 1990

The cytoplasmic domain of CD8 beta regulates Lck kinase activation and CD8 T cell development ⬇️

scientific article published on July 1, 1998

The effect of the immunosuppressant FK-506 on alternate pathways of T cell activation

scientific article

The extracellular signal-regulated kinase pathway is required for activation-induced cell death of T cells

scientific article published on 01 April 1999

The function of LFA-1 in cell-mediated killing and adhesion: studies on heritable LFA-1, Mac-1 deficiency and on lymphoid cell self-aggregation

scientific article published on 01 January 1985

The functional significance, distribution, and structure of LFA-1, LFA-2, and LFA-3: cell surface antigens associated with CTL-target interactions

article

The human HLA-specific monoclonal antibody W6/32 recognizes a discontinuous epitope within the alpha 2 domain of murine H-2Db

scientific article published on 01 January 1986

The immune response to Moloney murine leukemia virus-induced tumors: induction of cytolytic T lymphocytes specific for both viral and tumor-associated antigens

scientific article

The induction of cytolytic T lymphocytes with purified plasma membranes

scientific article

The induction of cytolytic T lymphocytes with specificity for p-azophenylarsonate coupled syngeneic cells ⬇️

scientific article published on October 1, 1978

The induction of cytolytic T lymphocytes with syngeneic trinitrophenyl-coupled membranes ⬇️

scientific article published on July 1, 1979

The induction of secondary cytolytic T lymphocytes by solubilized membrane proteins ⬇️

scientific article published on March 1, 1978

The induction of virus-specific cytotoxic T lymphocytes with solubilized viral and membrane proteins ⬇️

scientific article published on December 1, 1978

The interaction of CD4 with HIV-1 gp120.

scientific article published on May 1991

The mechanism of antigen presentation by dendritic cells and splenic adherent cells in the induction of an allogeneic cytotoxic T-lymphocyte response to H-2Kk liposomes

scientific article published on 01 July 1986

The origins of alloreactivity: differentiation of prekiller cells to viral infection results in alloreactive cytolytic T lymphocytes ⬇️

scientific article published on 01 April 1980

The regulation of exogenous and endogenous class I MHC genes in a human tumor cell line, K562.

scientific article published on February 1990

The role of CD18 in phorbol ester-induced human monocyte-mediated cytotoxicity

scientific article published on 01 August 1988

The role of L3T4 (CD4) in T-cell activation

scientific article published on 01 January 1987

The role of L3T4 in recognition of Ia by a cytotoxic, H-2Dd-specific T cell hybridoma ⬇️

scientific article published on April 1, 1984

The role of T cell accessory molecules in the generation of class II-specific xenogeneic cytolytic T cells

scientific article published on 01 April 1986

The role of calcineurin in lymphocyte activation

scientific article

The role of functional cell surface antigens in T cell activation

scientific article

The role of the L3T4 molecule in mitogen and antigen-activated signal transduction

scientific article published in June 1987

Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3

scientific article

Thy-1 is a differentiation antigen that characterizes immature murine erythroid and myeloid hematopoietic progenitors

scientific article published on 01 April 1985

Thymectomized, irradiated, and bone marrow-reconstituted chimeras have normal cytolytic T lymphocyte precursors but a defect in lymphokine production ⬇️

scientific article published on 01 May 1984

Transplantation. Antigen, co-stimulators and cytokines: regulators of allogeneic interactions

scientific article published on 01 October 1993

Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin

scientific article

Two sorting motifs, a ubiquitination motif and a tyrosine motif, are involved in HIV-1 and simian immunodeficiency virus Nef-mediated receptor endocytosis.

scientific article published on 11 April 2011

Type-specific reovirus antiserum blocks the cytotoxic T-cell-target cell interaction: evidence for the association of the viral hemagglutinin of a nonenveloped virus with the cell surface

scientific article

Tyrosine kinase activity of CD4-associated p56lck may not be required for CD4-dependent T-cell activation

scientific article published on December 1993

Tyrosine-phosphorylated Cbl binds to Crk after T cell activation.

scientific article

Uncoupling p70(s6) kinase activation and proliferation: rapamycin-resistant proliferation of human CD8(+) T lymphocytes

scientific article

Viral restricted cytolytic T lymphocyte recognition of hybrid human-murine class I histocompatibility antigens

scientific article published on 01 April 1986

Wnt-1 and Wnt-4 regulate thymic cellularity

scientific article published in April 2002

p56lck association with CD4 is required for the interaction between CD4 and the TCR/CD3 complex and for optimal antigen stimulation

scientific article published on 01 April 1992

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