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List of works by Steven M. Block

38 Versatile optical traps with feedback control

scientific article published on January 1, 1998

A DNA-based molecular probe for optically reporting cellular traction forces

scientific article

A miniature flow cell designed for rapid exchange of media under high-power microscope objectives

scientific article published on November 1984

A mutant hook-associated protein (HAP3) facilitates torsionally induced transformations of the flagellar filament of Escherichia coli

scientific article published in April 1994

A not-so-cheap stunt

scientific article published on 01 August 2002

A pause sequence enriched at translation start sites drives transcription dynamics in vivo

scientific article

A universal pathway for kinesin stepping ⬇️

scientific article published on August 14, 2011

Actin cores of hair-cell stereocilia support myosin motility

scientific article

Adaptation kinetics in bacterial chemotaxis

scientific article

An automated two-dimensional optical force clamp for single molecule studies

scientific article

An optical apparatus for rotation and trapping

scientific article

Analysis of high resolution recordings of motor movement

scientific article published on April 1995

Applied Force Provides Insight into Transcriptional Pausing and Its Modulation by Transcription Factor NusA ⬇️

scientific article published on November 18, 2011

Applied force reveals mechanistic and energetic details of transcription termination

scientific article

Backsteps induced by nucleotide analogs suggest the front head of kinesin is gated by strain

scholarly article

Backtracking by single RNA polymerase molecules observed at near-base-pair resolution

scientific article

Bead movement by single kinesin molecules studied with optical tweezers

scientific article

Binding and translocation of termination factor rho studied at the single-molecule level

scientific article published on 9 August 2012

Biological applications of optical forces

scientific article published on January 1994

Biophysical principles of sensory transduction

scientific article published on January 1, 1992

Characterization of photodamage to Escherichia coli in optical traps.

scientific article

Combined optical trapping and single-molecule fluorescence

scientific article

Compliance of bacterial flagella measured with optical tweezers

scientific article published on April 1989

Compliance of bacterial polyhooks measured with optical tweezers ⬇️

scientific article published on January 1, 1991

Conformation and elasticity of the isolated red blood cell membrane skeleton ⬇️

scientific article published on September 1, 1992

Coordination of flagella on filamentous cells of Escherichia coli ⬇️

scientific article published on July 1, 1983

Coordination of opposite-polarity microtubule motors

scientific article

Developmental regulation of vesicle transport in Drosophila embryos: forces and kinetics.

scientific article published on February 1998

Direct Observation of Cotranscriptional Folding in an Adenine Riboswitch ⬇️

scientific article published on October 19, 2012

Direct measurement of the full, sequence-dependent folding landscape of a nucleic acid

scientific article

Direct measurements of kinesin torsional properties reveal flexible domains and occasional stalk reversals during stepping

scientific article

Direct observation of base-pair stepping by RNA polymerase

scientific article

Direct observation of hierarchical folding in single riboswitch aptamers

scientific article published on 03 January 2008

Direct observation of kinesin stepping by optical trapping interferometry

scientific article published on October 1993

Direct observation of processive exoribonuclease motion using optical tweezers

scientific article

Direct observation of the binding state of the kinesin head to the microtubule

scientific article

Do's and don't's of poster presentation

scientific article published on December 1996

Dynein-mediated cargo transport in vivo. A switch controls travel distance

scientific article

E. coli NusG inhibits backtracking and accelerates pause-free transcription by promoting forward translocation of RNA polymerase

scientific article published on 8 April 2010

Efficient reconstitution of transcription elongation complexes for single-molecule studies of eukaryotic RNA polymerase II ⬇️

scientific article published on May 1, 2012

Eg5 steps it up!

scientific article

Electrostatics of Nucleic Acid Folding under Conformational Constraint ⬇️

scientific article published on February 27, 2012

Estimating the persistence length of a worm-like chain molecule from force-extension measurements

scientific article

Examining kinesin processivity within a general gating framework.

scientific article published on 22 April 2015

Fifty ways to love your lever: myosin motors

scientific article published on October 1996

Fluctuation analysis of kinesin movement

scientific article published on April 1995

Fluctuation analysis of motor protein movement and single enzyme kinetics

scientific article

Folding and unfolding single RNA molecules under tension

scientific article

Folding energy landscape of the thiamine pyrophosphate riboswitch aptamer ⬇️

scientific article published on January 4, 2012

Force and Velocity Measured for Single Molecules of RNA Polymerase ⬇️

scientific article published on October 30, 1998

Force and premature binding of ADP can regulate the processivity of individual Eg5 dimers

scientific article

Force and velocity measured for single kinesin molecules

scientific article published on 01 June 1994

Force production by single kinesin motors

scientific article published in October 2000

Forward and reverse motion of single RecBCD molecules on DNA.

scientific article

Getting high on Single Molecule Biophysics

scientific article published on August 2009

High-resolution, single-molecule measurements of biomolecular motion

scientific article

Impulse responses in bacterial chemotaxis

scientific article published on 01 November 1982

Individual dimers of the mitotic kinesin motor Eg5 step processively and support substantial loads in vitro

scientific article

Intraflagellar transport velocity is governed by the number of active KIF17 and KIF3AB motors and their motility properties under load

scientific article published on 31 July 2017

KIF15 nanomechanics and kinesin inhibitors, with implications for cancer chemotherapeutics.

scientific article published on 27 April 2018

Kinesin hydrolyses one ATP per 8-nm step ⬇️

scientific article published on July 24, 1997

Kinesin motor mechanics: binding, stepping, tracking, gating, and limping

scientific article published on 26 February 2007

Kinesin moves by an asymmetric hand-over-hand mechanism

scientific article published on 4 December 2003

Kinesin processivity is gated by phosphate release

scientific article

Kinesin steps do not alternate in size

scientific article published on 14 December 2007

Kinesin: What Gives? ⬇️

scientific article published on April 3, 1998

Leading the Procession: New Insights into Kinesin Motors ⬇️

scientific article published on March 23, 1998

Light and dark adaptation in Phycomyces light-growth response

scientific article

Making light work with optical tweezers.

scientific article

Measurement of the effective focal shift in an optical trap

scientific article published in June 2005

Molecule by molecule, the physics and chemistry of life: SMB 2007.

scientific article published on April 2007

Movement of myosin fragments in vitro: domains involved in force production

scientific article published on 01 March 1987

Myosin movement in vitro: a quantitative assay using oriented actin cables from Nitella

scientific article published on 01 January 1986

Nanomechanical measurements of the sequence-dependent folding landscapes of single nucleic acid hairpins

scholarly article

Nanometres and piconewtons: the macromolecular mechanics of kinesin

scientific article published on 01 April 1995

Not so lame after all: kinesin still walks with a hobbled head

scientific article published on November 2007

Observation of long-range tertiary interactions during ligand binding by the TPP riboswitch aptamer

scientific article published on 28 December 2015

Observing Single RNA Polymerase Molecules Down to Base-Pair Resolution

scientific article published in January 2017

On the origin of kinesin limping

scientific article published on September 2009

One small step for myosin..

scientific article published in Nature

Optical trapping

scientific article

Optical trapping of metallic Rayleigh particles

scientific article published on 01 July 1994

Optical tweezers study life under tension

scientific article published on May 2011

Passive all-optical force clamp for high-resolution laser trapping

scientific article published on 8 November 2005

Picocalorimetry of transcription by RNA polymerase

scientific article

Precision steering of an optical trap by electro-optic deflection.

scientific article

Probing the kinesin reaction cycle with a 2D optical force clamp

scholarly article

Pulling on the nascent RNA during transcription does not alter kinetics of elongation or ubiquitous pausing

scientific article published on July 2006

RNA BIOCHEMISTRY. Factor-dependent processivity in human eIF4A DEAD-box helicase

scientific article

Real engines of creation

scientific article published in Nature

Real-time observation of polymerase-promoter contact remodeling during transcription initiation

scientific article published on 27 October 2017

Real-time observation of the initiation of RNA polymerase II transcription

scientific article published on 2 September 2015

Reconstructing folding energy landscapes by single-molecule force spectroscopy

scientific article

Resource Letter: LBOT-1: Laser-based optical tweezers

scientific article

Role of ponticulin in pseudopod dynamics, cell-cell adhesion, and mechanical stability of an amoeboid membrane skeleton

scientific article published on 01 June 1998

Sequence-dependent pausing of single lambda exonuclease molecules.

scientific article

Sequence-resolved detection of pausing by single RNA polymerase molecules.

scientific article published on June 2006

Simultaneous, coincident optical trapping and single-molecule fluorescence

scientific article

Single kinesin molecules studied with a molecular force clamp

scientific article published in Nature

Single-Molecule Studies of RNA Polymerase: One Singular Sensation, Every Little Step It Takes ⬇️

scientific article published on February 4, 2011

Single-molecule studies of RNA polymerase: motoring along

scientific article published on January 2008

Single-molecule studies of RNAPII elongation

scientific article published on 06 September 2012

Single-molecule studies of riboswitch folding.

scientific article published on 13 April 2014

Single-molecule, motion-based DNA sequencing using RNA polymerase

scientific article

Statistical kinetics of macromolecular dynamics

scientific article published on 22 July 2005

Statistical kinetics of processive enzymes

scientific article published on 01 January 1995

Stepping and stretching. How kinesin uses internal strain to walk processively

scientific article

Stretching DNA with optical tweezers

scientific article

Stretching of single collapsed DNA molecules

scientific article

Successive incorporation of force-generating units in the bacterial rotary motor ⬇️

scientific article published on July 1, 1984

Temporal comparisons in bacterial chemotaxis

scientific article published on December 1986

The Growing Threat of Biological Weapons

The Mechanochemical Cycle of Mammalian Kinesin-2 KIF3A/B under Load

scientific article

The importance of lattice defects in katanin-mediated microtubule severing in vitro

scientific article

Transcription against an applied force

scientific article

Transcription factors TFIIF and TFIIS promote transcript elongation by RNA polymerase II by synergistic and independent mechanisms

scientific article

Trigger loop dynamics mediate the balance between the transcriptional fidelity and speed of RNA polymerase II.

scientific article published on 9 April 2012

UK defence group's structure could limit its usefulness

scientific article published in Nature

Ubiquitous transcriptional pausing is independent of RNA polymerase backtracking.

scientific article

Visualization of bacterial flagella by video-enhanced light microscopy

scientific article published on January 1991

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