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List of works by Steven A. Benner

"Skinny" and "Fat" DNA: Two New Double Helices

scientific article published on 10 September 2018

2'-deoxy-1-methylpseudocytidine, a stable analog of 2'-deoxy-5-methylisocytidine.

scientific article published on 27 March 2009

2-Hydroxymethylboronate as a reagent to detect carbohydrates: application to the analysis of the formose reaction

scientific article published in December 2006

A Direct Prebiotic Synthesis of Nicotinamide Nucleotide

scientific article published on 30 November 2017

A Single Deoxynucleoside Kinase Variant from Drosophila melanogaster Synthesizes Monophosphates of Nucleosides That Are Components of an Expanded Genetic System

scientific article

A combinatorial distance-constraint approach to predicting protein tertiary models from known secondary structure ⬇️

scientific article published on January 1, 1998

A convenient synthesis of N,N'-dibenzyl-2,4-diaminopyrimidine-2'-deoxyribonucleoside and 1-methyl-2'-deoxypseudoisocytidine

scientific article published in April 2009

A norovirus detection architecture based on isothermal amplification and expanded genetic systems

scientific article published on 18 August 2016

A predicted consensus structure for the N-terminal fragment of the heat shock protein HSP90 family

scientific article published in March 1997

A review: synthesis of aryl C-glycosides via the heck coupling reaction

scientific article published on January 2006

A word in your protein

scientific article published in Nature

Affinity maturation of a portable Fab-RNA module for chaperone-assisted RNA crystallography

scientific article published on 4 January 2018

Alternative Watson-Crick Synthetic Genetic Systems

scientific article published on 23 September 2016

Amino acid substitution during functionally constrained divergent evolution of protein sequences

scientific article published in November 1994

Amplification, mutation, and sequencing of a six-letter synthetic genetic system

scientific article

An Aptamer-Nanotrain Assembled from Six-Letter DNA Delivers Doxorubicin Selectively to Liver Cancer Cells

scientific article published on 19 November 2019

Analysis of combinatorial libraries using electrospray Fourier transform ion cyclotron resonance mass spectrometry

scientific article published on January 1996

Analysis of transitions at two-fold redundant sites in mammalian genomes. Transition redundant approach-to-equilibrium (TREx) distance metrics

scientific article

Application of DETECTER, an evolutionary genomic tool to analyze genetic variation, to the cystic fibrosis gene family

scientific article

Aptamers against Cells Overexpressing Glypican 3 from Expanded Genetic Systems Combined with Cell Engineering and Laboratory Evolution

scientific article

Artificial genetic systems: exploiting the "aromaticity" formalism to improve the tautomeric ratio for isoguanosine derivatives

scientific article

Artificial genetic systems: self-avoiding DNA in PCR and multiplexed PCR.

scientific article

Artificially Expanded Genetic Information Systems for New Aptamer Technologies.

scientific article published on 9 May 2018

Artificially expanded genetic information system: a new base pair with an alternative hydrogen bonding pattern

scientific article

Assays To Detect the Formation of Triphosphates of Unnatural Nucleotides: Application to Escherichia coli Nucleoside Diphosphate Kinase

scientific article published in February 2016

Biophysics of Artificially Expanded Genetic Information Systems. Thermodynamics of DNA Duplexes Containing Matches and Mismatches Involving 2-Amino-3-nitropyridin-6-one (Z) and Imidazo[1,2-a]-1,3,5-triazin-4(8H)one (P).

scientific article

Borate minerals stabilize ribose

scientific article (publication date: 9 January 2004)

C-5 modified nucleosides: direct insertion of alkynyl-thio functionality in pyrimidines

scientific article published in April 2003

Catalysts, Anticatalysts, and Receptors for Unactivated Phosphate Diesters in Water ⬇️

scientific article published on October 29, 1999

Challenging artificial genetic systems: thymidine analogs with 5-position sulfur functionality

scientific article

Conversion strategy using an expanded genetic alphabet to assay nucleic acids

scientific article published on 17 April 2013

Crystal structures of deprotonated nucleobases from an expanded DNA alphabet

scientific article published on 7 November 2016

Design of a novel molecular beacon: modification of the stem with artificially genetic alphabet

scientific article published on 26 September 2008

Detecting Darwinism from Molecules in the Enceladus Plumes, Jupiter's Moons, and Other Planetary Water Lagoons

scientific article published on 30 June 2017

Detecting compensatory covariation signals in protein evolution using reconstructed ancestral sequences

scientific article published in June 2002

Detecting respiratory viral RNA using expanded genetic alphabets and self-avoiding DNA.

scientific article published on 20 August 2015

Directed evolution of polymerases to accept nucleotides with nonstandard hydrogen bond patterns

scientific article published on 23 July 2013

Dynamic assembly of primers on nucleic acid templates

scientific article published on 8 September 2006

Eliminating primer dimers and improving SNP detection using self-avoiding molecular recognition systems

scientific article published on 10 February 2020

Empirical and structural models for insertions and deletions in the divergent evolution of proteins

scientific article published in February 1993

Enzymatic incorporation of a new base pair into DNA and RNA

scientific article

Enzymatic incorporation of a new base pair into DNA and RNA extends the genetic alphabet ⬇️

scientific article published on January 4, 1990

Enzymatic incorporation of a third nucleobase pair

scientific article published on 18 June 2007

Enzymic recognition of the base pair between isocytidine and isoguanosine ⬇️

scientific article published on October 5, 1993

Evaluation measures of multiple sequence alignments

scientific article (publication date: 2000)

Evolution of functional six-nucleotide DNA.

scientific article published on 20 May 2015

Evolutionary history of the uterine serpins

scientific article

Evolutionary, mechanistic, and predictive analyses of the hydroxymethyldihydropterin pyrophosphokinase family of proteins

scientific article

Exhaustive matching of the entire protein sequence database

scientific article

Expanded genetic alphabets in the polymerase chain reaction

scientific article

Expanding the genetic lexicon: incorporating non-standard amino acids into proteins by ribosome-based synthesis

scientific article

Extracellular 'communicator RNA'.

scientific article published on June 1988

Fluorescent charge-neutral analogue of xanthosine: synthesis of a 2'-deoxyribonucleoside bearing a 5-aza-7-deazaxanthine base

scientific article published in July 2001

Fourier transform-ion cyclotron resonance mass spectrometric resolution, identification, and screening of non-covalent complexes of Hck Src homology 2 domain receptor and ligands from a 324-member peptide combinatorial library

scientific article

Free energy differences between enzyme bound states

scientific article published in August 1987

Function-structure analysis of proteins using covarion-based evolutionary approaches: Elongation factors

scientific article

Hachimoji DNA and RNA: A genetic system with eight building blocks

scientific article published in Science

Helicase-Dependent Isothermal Amplification of DNA and RNA by Using Self-Avoiding Molecular Recognition Systems

scientific article published on 7 May 2015

High-throughput multiplexed xMAP Luminex array panel for detection of twenty two medically important mosquito-borne arboviruses based on innovations in synthetic biology

scientific article published on 11 February 2015

Hominids adapted to metabolize ethanol long before human-directed fermentation

scientific article

Incorporation of multiple sequential pseudothymidines by DNA polymerases and their impact on DNA duplex structure

scientific article published in March 2008

Inferring the palaeoenvironment of ancient bacteria on the basis of resurrected proteins

scientific article

Integrating protein structures and precomputed genealogies in the Magnum database: examples with cellular retinoid binding proteins

scientific article

Is there a common chemical model for life in the universe?

scientific article

Labeled Nucleoside Triphosphates with Reversibly Terminating Aminoalkoxyl Groups ⬇️

scientific article published on November 1, 2010

Laboratory evolution of artificially expanded DNA gives redesignable aptamers that target the toxic form of anthrax protective antigen

scientific article published on 03 October 2016

Modern metabolism as a palimpsest of the RNA world

scientific article

Multiplexed genetic analysis using an expanded genetic alphabet

scientific article

Natural progression

scientific article published in Nature

Natural selection, protein engineering, and the last riboorganism: rational model building in biochemistry

scientific article published in January 1987

Nucleoside alpha-thiotriphosphates, polymerases and the exonuclease III analysis of oligonucleotides containing phosphorothioate linkages

scientific article published on 22 April 2007

OligArch: A software tool to allow artificially expanded genetic information systems (AEGIS) to guide the autonomous self-assembly of long DNA constructs from multiple DNA single strands

scientific article published on 11 August 2014

Oligodeoxyribonucleotide analogues with bridging dimethylene sulfide, sulfoxide, and sulfone groups. Toward a second-generation model of nucleic acid structure

scientific article

PCR amplification of DNA containing non-standard base pairs by variants of reverse transcriptase from Human Immunodeficiency Virus-1

scientific article

Patterns of divergence in homologous proteins as indicators of tertiary and quaternary structure

scientific article

Phosphates, DNA, and the search for nonterrean life: a second generation model for genetic molecules

scientific article

Planetary systems biology

scientific article

Polymerase Interactions with Wobble Mismatches in Synthetic Genetic Systems and Their Evolutionary Implications

scientific article published on 27 June 2016

Post-genomic science: converting primary structure into physiological function ⬇️

scientific article published on January 1, 1998

Prebiotic Chemistry that Could Not Not Have Happened

scientific article published on 14 November 2019

Prebiotic stereoselective synthesis of purine and noncanonical pyrimidine nucleotide from nucleobases and phosphorylated carbohydrates

scientific article published on 9 October 2017

Predicting functional divergence in protein evolution by site-specific rate shifts

scientific article

Probing minor groove recognition contacts by DNA polymerases and reverse transcriptases using 3-deaza-2'-deoxyadenosine

scientific article

Pseudogenes in ribonuclease evolution: a source of new biomacromolecular function?

scientific article

Q&A: Life, synthetic biology and risk

scientific article

Quantitative analysis of a RNA-cleaving DNA catalyst obtained via in vitro selection

scientific article published in September 2004

Quantitative analysis of receptors for adenosine nucleotides obtained via in vitro selection from a library incorporating a cationic nucleotide analog

scientific article

Recognition by viral and cellular DNA polymerases of nucleosides bearing bases with nonstandard hydrogen bonding patterns

scientific article

Recognition of an expanded genetic alphabet by type-II restriction endonucleases and their application to analyze polymerase fidelity ⬇️

scientific article published on January 17, 2011

Recombinase-based isothermal amplification of nucleic acids with self-avoiding molecular recognition systems (SAMRS).

scientific article

Reconstructed evolutionary adaptive paths give polymerases accepting reversible terminators for sequencing and SNP detection

scientific article

Reconstructing the evolutionary history of the artiodactyl ribonuclease superfamily

scientific article

Resurrecting ancestral alcohol dehydrogenases from yeast

scientific article (publication date: June 2005)

Ribonucleosides for an artificially expanded genetic information system

scientific article published on 18 March 2014

Self-Avoiding Molecular Recognition Systems (SAMRS).

scientific article

Setting the Stage: The History, Chemistry, and Geobiology behind RNA ⬇️

scientific article published on January 1, 2012

Signatures of a shadow biosphere

scientific article

Solubility of polyethers in hydrocarbons at low temperatures. A model for potential genetic backbones on warm titans

scientific article

Standard and AEGIS nicking molecular beacons detect amplicons from the Middle East respiratory syndrome coronavirus

scientific article published on 12 July 2016

Structural basis for a six nucleotide genetic alphabet

scientific article

Structural determinants of stereospecificity in yeast alcohol dehydrogenase

scientific article published on October 1991

Structure and Biophysics for a Six Letter DNA Alphabet that Includes Imidazo[1,2-a]-1,3,5-triazine-2(8H)-4(3H)-dione (X) and 2,4-Diaminopyrimidine (K).

scientific article published on 28 July 2017

Structure prediction in a post-genomic environment: a secondary and tertiary structural model for the initiation factor 5A family

scientific article

Synthesis and Biodistribution of a Short Nonionic Oligonucleotide Analogue in Mouse with a Potential to Mimic Peptides ⬇️

scientific article published on January 29, 1998

Synthesis and Enzymology of 2'-Deoxy-7-deazaisoguanosine Triphosphate and Its Complement: A Second Generation Pair in an Artificially Expanded Genetic Information System

scientific article published on 25 February 2016

Synthesis of pyrophosphates for in vitro selection of catalytic RNA molecules

scientific article

Synthesis, structure and activity of artificial, rationally designed catalytic polypeptides

scientific article

Synthetic biology

scientific article

Synthetic biology for improved personalized medicine

scientific article published on January 2008

The "strong" RNA world hypothesis: fifty years old.

scientific article

The NASA Astrobiology Roadmap

scientific article

The challenges of sequencing by synthesis

scientific article

The crystal structure of eEF1A refines the functional predictions of an evolutionary analysis of rate changes among elongation factors

scientific article published in April 2002

The design of synthetic genes

scientific article

The evolution of seminal ribonuclease: pseudogene reactivation or multiple gene inactivation events?

scientific article

The last ribo-organism

scientific article published in September 1987

The missing organic molecules on Mars

scientific article

The natural history of class I primate alcohol dehydrogenases includes gene duplication, gene loss, and gene conversion

scientific article (publication date: 2012)

The past as the key to the present: resurrection of ancient proteins from eosinophils

scientific article

The planetary biology of ascorbate and uric acid and their relationship with the epidemic of obesity and cardiovascular disease

scientific article published on 10 March 2008

The planetary biology of cytochrome P450 aromatases

scientific article

The return of pancreatic ribonucleases

scientific article

The ribonuclease from an extinct bovid ruminant

scientific article published in March 1990

The use of thymidine analogs to improve the replication of an extra DNA base pair: a synthetic biological system

scientific article

Transcription, reverse transcription, and analysis of RNA containing artificial genetic components

scientific article

Uncertainty in ancient phylogenies

scientific article published in Nature

Understanding nucleic acids using synthetic chemistry

scientific article published in October 2004

Unite efforts and conquer mysteries of artificial genetics.

scientific article

Uniting Natural History with the Molecular Sciences. The Ultimate Multidisciplinarity

scientific article

Unusual Hydrogen Bonding Patterns and the Role of the Backbone in Nucleic Acid Information Transfer

scientific article published on 22 November 2016

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