List of works by Stephen Dunnett

A Critical Re-Examination of the Intraluminal Filament MCAO Model: Impact of External Carotid Artery Transection

scientific article

A Longitudinal Motor Characterisation of the HdhQ111 Mouse Model of Huntington's Disease

scientific article published on 31 May 2016

A Longitudinal Operant Assessment of Cognitive and Behavioural Changes in the HdhQ111 Mouse Model of Huntington's Disease

scientific article published on 04 October 2016

A Prospective Pilot Trial for Pallidal Deep Brain Stimulation in Huntington's Disease.

scientific article published on 18 August 2015

A combination drug therapy improves cognition and reverses gene expression changes in a mouse model of Huntington's disease.

scientific article published in February 2005

A comparative study of preparation techniques for improving the viability of nigral grafts using vital stains, in vitro cultures, and in vivo grafts

scientific article published on 01 March 1995

A comparison of the behavioural effects of embryonic nigral grafts in the caudate nucleus and in the putamen of marmosets with unilateral 6-OHDA lesions

scientific article published on 01 January 1995

A novel extended sequence learning task (ESLeT) for rodents: validation and the effects of amphetamine, scopolamine and striatal lesions.

scientific article published on 20 October 2010

A numerical investigation into the flow field around a worker positioned by an exhaust opening

scientific article published on 01 October 1994

A quantitative study of cell death in the substantia nigra following a mechanical lesion of the medial forebrain bundle

scientific article published on 01 January 1995

A role for complement in the rejection of porcine ventral mesencephalic xenografts in a rat model of Parkinson's disease.

scientific article

A selective tachykinin receptor agonist promotes differentiation but not survival of rat chromaffin cells in vitro ⬇️

scientific article published on January 1, 1993

A simple breeding protocol for the procurement of accurately staged rat donor embryos for neural transplantation.

scientific article published in January 2009

Abnormal synaptic plasticity and impaired spatial cognition in mice transgenic for exon 1 of the human Huntington's disease mutation.

scientific article published in July 2000

Acetylcholine-rich neuronal grafts in the forebrain of rats: effects of environmental enrichment, neonatal noradrenaline depletion, host transplantation site and regional source of embryonic donor cells on graft size and acetylcholinesterase-positiv

scientific article published in July 1986

Acetylcholine-rich transplants in the hippocampus: influence of intrinsic growth factors and application of nerve growth factor on choline acetyltransferase activity

scientific article published in October 1985

Activin A directs striatal projection neuron differentiation of human pluripotent stem cells

scientific article

Addition of fresh blood to intrastriatal grafts of embryonic mesencephalon into the hemiparkinsonian rat does not impair the survival of grafted dopaminergic neurones

scientific article published in March 1999

Age-dependence of malonate-induced striatal toxicity.

scientific article published in October 2000

Age-dependent maintenance of motor control and corticostriatal innervation by death receptor 3.

scientific article

Altered mitogen-activated protein kinase signaling, tau hyperphosphorylation and mild spatial learning dysfunction in transgenic rats expressing the beta-amyloid peptide intracellularly in hippocampal and cortical neurons.

scientific article published in January 2004

Amelioration of non-motor dysfunctions after transplantation of human dopamine neurons in a model of Parkinson's disease

scientific article published on 3 February 2016

Amphetamine induced rotation in the assessment of lesions and grafts in the unilateral rat model of Parkinson's disease

scientific article

Amphetamine-induced dyskinesia in the transplanted hemi-Parkinsonian mouse.

scientific article published on January 2012

Amphetamine-induced rotation in the transplanted hemi-parkinsonian rat--response to pharmacological modulation

scientific article published on 9 April 2012

An investigation of the problem of two-layered immunohistochemical staining in paraformaldehyde fixed sections

scientific article

An operant serial implicit learning task (SILT) in rats: task acquisition, performance and the effects of striatal lesions

scientific article

Analysis of skilled forelimb movement in rats: the single pellet reaching test and staircase test

scientific article published in January 2012

Animal models of Parkinson's disease and L-dopa induced dyskinesia: how close are we to the clinic?

scientific article published on 25 September 2007

Antioxidant strategy to counteract the side effects of antipsychotic therapy: an in vivo study in rats

scientific article published on 01 November 2000

Ascorbic acid increases the number of dopamine neurons in vitro and in transplants to the 6-OHDA-lesioned rat brain

scientific article

Assessment of Motor Coordination and Balance in Mice Using the Rotarod, Elevated Bridge, and Footprint Tests.

scientific article

Assessment of striatal graft viability in the rat in vivo using a small diameter PET scanner

scientific article published on 01 October 1995

Assessment of the relationship between pre-chip and post-chip quality measures for Affymetrix GeneChip expression data

scientific article

Basic fibroblast growth factor promotes the survival of embryonic ventral mesencephalic dopaminergic neurons--I. Effects in vitro.

scientific article published in September 1993

Basic fibroblast growth factor promotes the survival of embryonic ventral mesencephalic dopaminergic neurons--II. Effects on nigral transplants in vivo

scientific article published on 01 September 1993

Basic neural transplantation techniques. I. Dissociated cell suspension grafts of embryonic ventral mesencephalon in the adult rat brain

scientific article published on 01 February 1997

Behavioral analysis of motor and non-motor symptoms in rodent models of Parkinson's disease.

scientific article published on January 2010

Behavioral and neurochemical evaluation of a transgenic mouse model of Lesch-Nyhan syndrome.

scientific article published in September 1988

Behavioral assessment of the ability of intracerebral embryonic neural tissue grafts to ameliorate the effects of brain damage in marmosets

scientific article published on 01 August 1994

Behavioral assessment of the effects of embryonic nigral grafts in marmosets with unilateral 6-OHDA lesions of the nigrostriatal pathway.

scientific article published in February 1994

Behavioral recovery after transplantation into a rat model of Huntington's disease: dependence on anatomical connectivity and extensive postoperative training

scientific article published in April 2000

Behavioural effects of subthalamic nucleus lesions in the hemiparkinsonian marmoset (Callithrix jacchus).

scientific article published in February 1998

Behavioural profiles of inbred mouse strains used as transgenic backgrounds. I: motor tests.

scientific article published in August 2004

Behavioural recovery following striatal transplantation: effects of postoperative training and P-zone volume.

scientific article published in October 1999

Behavioural recovery following transplantation of substantia nigra in rats subjected to 6-OHDA lesions of the nigrostriatal pathway. I. Unilateral lesions.

scientific article published in June 1981

Behavioural recovery following transplantation of substantia nigra in rats subjected to 6-OHDA lesions of the nigrostriatal pathway. II. Bilateral lesions

scientific article published in December 1981

Behavioural recovery on simple and complex tasks by means of cell replacement therapy in unilateral 6-hydroxydopamine-lesioned mice

scientific article published on 25 February 2013

Bilateral striatal lesions disrupt performance in an operant delayed reinforcement task in rats.

scientific article published on 15 April 2011

Bilateral striatal lesions impair retention of an operant test of short-term memory.

scientific article published in January 1996

Brain gene expression correlates with changes in behavior in the R6/1 mouse model of Huntington's disease.

scientific article published on 13 August 2007

Brain repair in a unilateral rat model of Huntington's disease: new insights into impairment and restoration of forelimb movement patterns

scientific article published on 12 October 2012

Brain-derived neurotrophic factor (BDNF) overexpression in the forebrain results in learning and memory impairments.

scientific article published on 27 November 2008

Bridge grafts of fibroblast growth factor-4-secreting schwannoma cells promote functional axonal regeneration in the nigrostriatal pathway of the adult rat.

scientific article published in October 1996

CNS transplantation: structural and functional recovery from brain damage.

scientific article published in January 1982

Caspase inhibition increases embryonic striatal graft survival

scientific article published on 01 July 2000

Cell therapy for Huntington's disease, the next step forward.

scientific article

Cell therapy in Huntington's disease.

scientific article

Cell therapy in Parkinson's disease - stop or go?

scientific article published in May 2001

Cell transplantation for Huntington's disease

scientific article published in April 2006

Cell-based treatments for huntington's disease.

scientific article published on January 2011

Cellular localisation of somatostatin mRNA and neuropeptide Y mRNA in foetal striatal tissue grafts

scientific article published on 01 August 1989

Challenges for taking primary and stem cells into clinical neurotransplantation trials for neurodegenerative disease.

scientific article

Chapter 55: neural transplantation

scientific article published in January 2010

Characterisation of spatial neglect induced by unilateral 6-OHDA lesions on a choice reaction time task in rats.

scientific article published on 27 September 2012

Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation.

scientific article

Cholecystokinin-dependent regulation of host dopamine inputs to striatal grafts

scientific article

Cholinergic grafts, memory and ageing ⬇️

scientific article published on August 1, 1991

Clinical and genetic characteristics of late-onset Huntington's disease

scientific article

Co-expression of MAP-2 and GFAP in cells developing from rat EGF responsive precursor cells

scientific article published in February 1997

Cognitive deficits in animal models of basal ganglia disorders.

scientific article

Cognitive dysfunction and depression in Parkinson's disease: what can be learned from rodent models?

scientific article

Cognitive function. Acetylcholine revisited.

scientific article published in June 1995

Cognitive training modifies disease symptoms in a mouse model of Huntington's disease

scientific article

Comparative analysis of pathology and behavioural phenotypes in mouse models of Huntington's disease

scientific article published on 08 October 2011

Comparison of 6-hydroxydopamine lesions of the substantia nigra and the medial forebrain bundle on a lateralised choice reaction time task in mice

scientific article published in November 2012

Comparison of 6-hydroxydopamine-induced medial forebrain bundle and nigrostriatal terminal lesions in a lateralised nose-poking task in rats

scientific article published on 26 November 2004

Comparison of 6-hydroxydopamine-induced medial forebrain bundle and nigrostriatal terminal lesions in rats using a lateralised nose-poking task with low stimulus-response compatibility

scientific article published on 31 August 2005

Comparison of adrenal and foetal nigral grafts on drug-induced rotation in rats with 6-OHDA lesions

scientific article published on 01 January 1989

Comparison of incremental and accelerating protocols of the rotarod test for the assessment of motor deficits in the 6-OHDA model

scientific article published on 11 July 2006

Comparison of mHTT Antibodies in Huntington's Disease Mouse Models Reveal Specific Binding Profiles and Steady-State Ubiquitin Levels with Disease Development

scientific article

Comparison of rating scales used to evaluate L-DOPA-induced dyskinesia in the 6-OHDA lesioned rat.

scientific article published on 13 October 2012

Complement regulatory proteins are expressed at low levels in embryonic human, wild type and transgenic porcine neural tissue

scientific article published in January 2004

Conditioned turning in rats: dopaminergic involvement in the initiation of movement rather than the movement itself

scientific article published in October 1983

Conditioning versus priming of dopaminergic grafts by amphetamine.

scientific article published in January 1993

Context-driven changes in L-DOPA-induced behaviours in the 6-OHDA lesioned rat.

scientific article published on 8 January 2011

Controversies in neuroscience

scientific article published in September 2002

Correction: Huntingtin Subcellular Localisation Is Regulated by Kinase Signalling Activity in the StHdhQ111 Model of HD

scientific article published on 13 October 2016

Corrigendum: Motivational, proteostatic and transcriptional deficits precede synapse loss, gliosis and neurodegeneration in the B6.HttQ111/+ model of Huntington's disease.

scientific article published on 28 March 2017

Cross-species neural grafting in a rat model of Parkinson's disease

scientific article published in August 1982

Death of dopaminergic neurons in vitro and in nigral grafts: reevaluating the role of caspase activation

scientific article published in September 2001

Decreased brown adipose tissue thermogenic activity following a reduction in brain serotonin by intraventricular p-chlorophenylalanine

scientific article published on 01 February 1987

Deficits in a lateralized associative learning task in dopamine-depleted rats with functional recovery by dopamine-rich transplants

scientific article published in October 2004

Delay-dependent short-term memory deficits in aged rats.

scientific article published in January 1988

Delayed implantation of nigral grafts improves survival of dopamine neurones and rate of functional recovery.

scientific article

Developmentally coordinated extrinsic signals drive human pluripotent stem cell differentiation toward authentic DARPP-32+ medium-sized spiny neurons

scientific article published in January 2013

Differential effects of unilateral striatal and nigrostriatal lesions on grip strength, skilled paw reaching and drug-induced rotation in the rat.

scientific article

Differential expression of immediate early genes in the hippocampus and spinal cord.

scientific article

Differentiation of pluripotent stem cells into striatal projection neurons: a pure MSN fate may not be sufficient

scientific article

Direct Comparison of Rat- and Human-Derived Ganglionic Eminence Tissue Grafts on Motor Function.

scientific article published on 29 December 2015

Disappearance of the mu-opiate receptor patches in the rat neostriatum following lesioning of the ipsilateral nigrostriatal dopamine pathway with 1-methyl-4-phenylpyridinium ion (MPP+): restoration by embryonic nigral dopamine grafts

scientific article published on 01 December 1989

Dissociable roles of the ventral, medial and lateral striatum on the acquisition and performance of a complex visual stimulus-response habit

scientific article published in November 1991

Distinct roles for striatal subregions in mediating response processing revealed by focal excitotoxic lesions.

scientific article

Dopamine and cholecystokinin immunoreactive neurons in mesencephalic grafts reinnervating the neostriatum: evidence for selective growth regulation

scientific article published in May 1984

Dopamine cells in nigral grafts differentiate prior to implantation

scientific article published on 01 December 1999

Dopamine depletion, stimulation or blockade in the rat disrupts spatial navigation and locomotion dependent upon beacon or distal cues

scientific article published in October 1985

Dopamine neuron systems in the brain: an update

scientific article

Dopamine-rich grafts alleviate deficits in contralateral response space induced by extensive dopamine depletion in rats.

scientific article published on 27 January 2013

Dopamine-rich grafts ameliorate whole body motor asymmetry and sensory neglect but not independent limb use in rats with 6-hydroxydopamine lesions.

scientific article published in July 1987

Dopamine-rich grafts in the neostriatum and/or nucleus accumbens: effects on drug-induced behaviours and skilled paw-reaching.

scientific article published in March 1993

Dopamine-rich transplants in rats with 6-OHDA lesions of the ventral tegmental area. I. Effects on spontaneous and drug-induced locomotor activity

scientific article published in July 1984

Dopaminergic grafts implanted into the neonatal or adult striatum: comparative effects on rotation and paw reaching deficits induced by subsequent unilateral nigrostriatal lesions in adulthood

scientific article published in June 1993

Dopaminergic neuronal survival and the effects of bFGF in explant, three dimensional and monolayer cultures of embryonic rat ventral mesencephalon

scientific article published on 01 January 1995

Double dissociation between hippocampal and prefrontal lesions on an operant delayed matching task and a water maze reference memory task

scientific article published on 4 May 2006

Drug repositioning for Alzheimer's disease.

scientific article

EGF and FGF-2 responsiveness of rat and mouse neural precursors derived from the embryonic CNS.

scientific article

Early onset deficits on the delayed alternation task in the Hdh(Q92) knock-in mouse model of Huntington's disease.

scientific article published on 31 March 2011

Effects of Nucleus Basalis Magnocellularis Lesions in Rats on Delayed Matching and Non-Matching to Position Tasks

scientific article published on 01 January 1990

Effects of Nucleus Basalis Magnocellularis Lesions in Rats on Delayed Matching and Non-Matching to Position Tasks.

scientific article published in July 1989

Effects of STN lesions on simple vs choice reaction time tasks in the rat: preserved motor readiness, but impaired response selection

scientific article published in April 2001

Effects of dopamine-rich grafts on conditioned rotation in rats with unilateral 6-hydroxydopamine lesions

scientific article published in July 1986

Effects of regional striatal lesions on motor, motivational, and executive aspects of progressive-ratio performance in rats.

scientific article

Effects of severity of host striatal damage on the morphological development of intrastriatal transplants in a rodent model of Huntington's disease: implications for timing of surgical intervention.

scientific article

Effects of surgical anaesthesia on the viability of nigral grafts in the rat striatum

scientific article published in November 1998

Effects of systemic 3-nitropropionic acid-induced lesions of the dorsal striatum on cannabinoid and mu-opioid receptor binding in the basal ganglia.

scientific article published in January 2000

Electrophysiological demonstration of host cortical inputs to striatal grafts

scientific article

Electrophysiological properties of single units in dopamine-rich mesencephalic transplants in rat brain

scientific article published in June 1985

Embryonic donor age and dissection influences striatal graft development and functional integration in a rodent model of Huntington's disease

scientific article published in May 2000

Embryonic striatal grafts restore bi-directional synaptic plasticity in a rodent model of Huntington's disease

scientific article published on 25 November 2009

Embryonic striatal grafts reverse the disinhibitory effects of ibotenic acid lesions of the ventral striatum.

scientific article

Environmental enrichment affects striatal graft morphology and functional recovery.

scientific article

Environmental enrichment facilitates long-term potentiation in embryonic striatal grafts.

scientific article published on 26 March 2011

Environmental housing and duration of exposure affect striatal graft morphology in a rodent model of Huntington's disease

scientific article published in January 2008

Exercise attenuates neuropathology and has greater benefit on cognitive than motor deficits in the R6/1 Huntington's disease mouse model

scientific article

Experimental hemiparkinsonism in the rat following chronic unilateral infusion of MPP+ into the nigrostriatal dopamine pathway--III. Reversal by embryonic nigral dopamine grafts

scientific article published on 01 January 1990

Expression of c-fos, jun D and pp60c-src+ mRNAs in the developing and grafted rat striatum

scientific article published in September 1996

Fetal porcine dopaminergic cell survival in vitro and its relationship to embryonic age

scientific article published on 01 November 1999

Fetal ventral mesencephalon of human and rat origin maintained in vitro and transplanted to 6-hydroxydopamine-lesioned rats gives rise to grafts rich in dopaminergic neurons.

scientific article

Fifty years of dopamine research

scientific article published on 29 March 2007

Five choice serial reaction time performance in the HdhQ92 mouse model of Huntington's disease

scientific article

Fluorescent histochemical demonstration of catecholamines in brown adipose tissue from obese (ob/ob) and lean mice acclimated at different temperatures

Frontal-striatal disconnection disrupts cognitive performance of the frontal-type in the rat.

scientific article

Fronto-striatal disconnection disrupts operant delayed alternation performance in the rat.

scientific article published in March 2006

Function recovery following neural transplantation of embryonic septal nuclei in adult rats with septohippocampal lesions

scientific article

Functional and anatomical reconstruction of the 6-hydroxydopamine lesioned nigrostriatal system of the adult rat.

scientific article

Functional correlates of compensatory collateral sprouting by aminergic and cholinergic afferents in the hippocampal formation.

scientific article published in May 1983

Functional integration of neural grafts in Parkinson's disease

scientific article published on 01 December 1999

Functional integration of striatal allografts in a primate model of Huntington's disease.

scientific article published on June 1998

Functional neural transplantation III. Primary and stem cell therapies for brain repair, part I. Introduction

scientific article published in January 2012

Gene expression and behaviour in mouse models of HD.

scientific article published on 10 August 2011

Gene expression in striatal grafts--I. Cellular localization of neurotransmitter mRNAs

scientific article published on 01 January 1990

Generating Excitotoxic Lesion Models of Huntington’s Disease

scientific article published on 01 January 2018

Genetic, temporal and diurnal influences on L-dopa-induced dyskinesia in the 6-OHDA model

scientific article

Graft-derived recovery from 6-OHDA lesions: specificity of ventral mesencephalic graft tissues

scientific article

Grafts of embryonic substantia nigra reinnervating the ventrolateral striatum ameliorate sensorimotor impairments and akinesia in rats with 6-OHDA lesions of the nigrostriatal pathway

scientific article published in December 1981

HSV vector-delivery of GDNF in a rat model of PD: partial efficacy obscured by vector toxicity

scientific article

Hippocampal lesions impair performance on a conditional delayed matching and non-matching to position task in the rat.

scientific article

Human Pluripotent Stem Cell-Derived Striatal Interneurons: Differentiation and Maturation In Vitro and in the Rat Brain

scientific article published on 17 January 2019

Human stem cells for CNS repair.

scientific article published on 28 September 2007

Huntingtin Subcellular Localisation Is Regulated by Kinase Signalling Activity in the StHdhQ111 Model of HD.

scientific article published on 14 December 2015

Hypersensitivity to alpha-methyl-p-tyrosine suggests that behavioural recovery of rats receiving neonatal 6-OHDA lesions is mediated by residual catecholamine neurones.

scientific article published in July 1989

Ibotenic acid lesions of the lateral hypothalamus: comparison with 6-hydroxydopamine-induced sensorimotor deficits

scientific article published in February 1985

Ibotenic acid lesions of the lateral hypothalamus: comparison with the electrolytic lesion syndrome

scientific article published in May 1984

Ibotenic acid lesions of the striatum reduce drug-induced rotation in the 6-hydroxydopamine-lesioned rat

scientific article published on 01 January 1994

Identification of novel alternative splicing events in the huntingtin gene and assessment of the functional consequences using structural protein homology modelling.

scientific article

Immortalized neural cells from trisomy 16 mice as models for Alzheimer's disease.

scientific article published on January 1996

Immunohistochemical identification of rat adrenal cortical tissue in situ, in vitro, and in intracerebral adrenal grafts

scientific article published in July 1993

Impact factor rises again

scientific article published on 01 December 2004

Impaired bidirectional synaptic plasticity and procedural memory formation in striatum-specific cAMP response element-binding protein-deficient mice.

scientific article

Impaired sensitivity to Pavlovian stimulus-outcome learning after excitotoxic lesion of the ventrolateral neostriatum

scientific article published on 18 August 2011

Improved survival of young donor age dopamine grafts in a rat model of Parkinson's disease.

scientific article

In vivo effects of kFGF on embryonic nigral grafts in a rat model of Parkinson's disease.

scientific article published on November 1995

In vivo measurement of spontaneous release and metabolism of dopamine from intrastriatal nigral grafts using intracerebral dialysis

scientific article published in January 1986

In vivo transgene expression from an adenoviral vector is altered following a 6-OHDA lesion of the dopamine system.

scientific article

Increased efficacy of the 6-hydroxydopamine lesion of the median forebrain bundle in small rats, by modification of the stereotaxic coordinates.

scientific article

Increased proenkephalin mRNA levels in the rat neostriatum following lesion of the ipsilateral nigrostriatal dopamine pathway with 1-methyl-4-phenylpyridinium ion (MPP+): reversal by embryonic nigral dopamine grafts

scientific article published on 01 February 1991

Increased survival of rat EGF-generated CNS precursor cells using B27 supplemented medium

scientific article published on 01 January 1995

Influence of chronic L-DOPA treatment on immune response following allogeneic and xenogeneic graft in a rat model of Parkinson's disease ⬇️

scientific article

Interactions between meningeal cells and astrocytes in vivo and in vitro ⬇️

scientific article published on April 24, 1991

Intracerebral grafting of embryonic neural cells into the adult host brain: an overview of the cell suspension method and its application.

scientific article published on January 1983

Intraspinal stem cell transplantation for amyotrophic lateral sclerosis: Ready for efficacy clinical trials?

scientific article

Intrastriatal dopamine-rich grafts induce a hyperexpression of Fos protein when challenged with amphetamine

scientific article published in January 1992

Intrastriatal grafts derived from fetal striatal primordia--IV. Host and donor neurons are not intermixed

scientific article published in July 1993

Introduction (Part II).

scientific article published in January 2012

Is the adult mouse striatum a hostile host for neural transplant survival?

scientific article published on December 2013

Is there a place for human fetal-derived stem cells for cell replacement therapy in Huntington's disease?

scientific article

Ivan Divac and the neostriatum as a cognitive structure

scientific article published in November 1999

L-DOPA, dyskinesia and striatal plasticity ⬇️

scientific article published on May 1, 2003

Latency associated promoter transgene expression in the central nervous system after stereotaxic delivery of replication-defective HSV-1-based vectors

scientific article published in July 2001

Lentivector-mediated delivery of GDNF protects complex motor functions relevant to human Parkinsonism in a rat lesion model.

scientific article published on November 2005

Lesions of the dorsomedial striatum impair formation of attentional set in rats.

scientific article published on 11 April 2013

Lesions of the premotor and supplementary motor areas fail to prevent implicit learning in the operant serial implicit learning task

scientific article

Lickometry: A novel and sensitive method for assessing functional deficits in rats after stroke.

scientific article

Light and electron microscopic characterization of the evolution of cellular pathology in HdhQ92 Huntington's disease knock-in mice.

scientific article published on 13 April 2011

Light and electron microscopic characterization of the evolution of cellular pathology in YAC128 Huntington's disease transgenic mice

scientific article

Light and electron microscopic characterization of the evolution of cellular pathology in the Hdh(CAG)150 Huntington's disease knock-in mouse.

scientific article published on 13 April 2011

Light and electron microscopic characterization of the evolution of cellular pathology in the R6/1 Huntington's disease transgenic mice.

scientific article

Localization of the mRNAs for the short and long isoforms of the dopamine D2 receptor in embryonic striatal grafts: predominance of the short isoform

scientific article published on 01 December 1994

Long-term expansion of human foetal neural progenitors leads to reduced graft viability in the neonatal rat brain

scientific article

Long-term hibernation of human fetal striatal tissue does not adversely affect its differentiation in vitro or graft survival: implications for clinical trials in Huntington's disease.

scientific article published in January 2003

Long-term restorative effects of bromocriptine on operant responding in the 6-hydroxydopamine-lesioned rat.

scientific article published in December 2013

Long-term survival of human central nervous system progenitor cells transplanted into a rat model of Parkinson's disease.

scientific article published in November 1997

Longitudinal analyses of operant performance on the serial implicit learning task (SILT) in the YAC128 Huntington's disease mouse line

scientific article

Longitudinal analysis of gene expression and behaviour in the HdhQ150 mouse model of Huntington's disease

scientific article

Longitudinal analysis of the behavioural phenotype in Hdh(CAG)150 Huntington's disease knock-in mice

scientific article published on 8 May 2010

Longitudinal analysis of the behavioural phenotype in HdhQ92 Huntington's disease knock-in mice

scientific article published on 10 May 2010

Longitudinal analysis of the behavioural phenotype in R6/1 (C57BL/6J) Huntington's disease transgenic mice

scientific article published on 25 January 2011

Longitudinal analysis of the behavioural phenotype in YAC128 (C57BL/6J) Huntington's disease transgenic mice

scientific article published on 10 May 2010

Mechanisms and use of neural transplants for brain repair.

scientific article published on 14 April 2017

Medial prefrontal and neostriatal lesions disrupt performance in an operant delayed alternation task in rats.

scientific article published in December 1999

Medical terminations of pregnancy: a viable source of tissue for cell replacement therapy for neurodegenerative disorders.

scientific article published on 7 March 2011

Medium spiny neurons for transplantation in Huntington's disease

scientific article

Membrane permeability coefficients of murine primary neural brain cells in the presence of cryoprotectant.

scientific article published on 11 March 2009

Microfluidic chip-based synthesis of alginate microspheres for encapsulation of immortalized human cells

scientific article published on 25 January 2007

Mitogenic effect of basic fibroblast growth factor on embryonic ventral mesencephalic dopaminergic neurone precursors

scientific article

Monoamine deficiency in a transgenic (Hprt-) mouse model of Lesch-Nyhan syndrome

scientific article

Monoclonal antibody G10 against microtubule-associated protein 1x distinguishes between growing and regenerating axons

scientific article published in January 1989

Morphological and cellular changes within embryonic striatal grafts associated with enriched environment and involuntary exercise.

scientific article

Motivational, proteostatic and transcriptional deficits precede synapse loss, gliosis and neurodegeneration in the B6.HttQ111/+ model of Huntington's disease

scientific article

Motor Assessment in Huntington's Disease Mice

scientific article published on 01 January 2018

Motor coordination and balance in rodents

scientific article published on 01 August 2001

Motor training effects on recovery of function after striatal lesions and striatal grafts.

scientific article published in November 2003

Mouse Models of Huntington's Disease

scientific article published on 01 January 2015

Movement without dopamine: striatal dopamine is required to maintain but not to perform learned actions

scientific article published in April 2007

Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage

scientific article

Myelination and behaviour of tenascin-C null transgenic mice.

scientific article published in September 1999

Neonatal desensitization allows long-term survival of neural xenotransplants without immunosuppression.

scientific article published on 8 March 2009

Neonatal dopamine-rich grafts and 6-OHDA lesions independently provide partial protection from the adult nigrostriatal lesion syndrome

scientific article published on 01 August 1989

Neural Transplantation in Animal Models of Dementia.

scientific article

Neural cells from primary human striatal xenografts migrate extensively in the adult rat CNS.

scientific article published in April 2002

Neural grafting in Parkinson's disease unraveling the mechanisms underlying graft-induced dyskinesia

scientific article published on January 2010

Neural tissue transplantation, repair, and rehabilitation

scientific article published in January 2013

Neural transplantation for the treatment of Parkinson's disease

scientific article

Neural transplantation: restoring complex circuitry in the striatum.

scientific article

Neuronal cell transplantation for Parkinson's and Huntington's diseases

scientific article

Neurorehabilitation with neural transplantation.

scientific article published on 20 July 2010

Neurotoxic amino acid lesions of the lateral hypothalamus: a parametric comparison of the effects of ibotenate, N-methyl-D,L-aspartate and quisqualate in the rat.

scientific article published in December 1985

Neurotoxic lesions of ventrolateral but not anteromedial neostriatum in rats impair differential reinforcement of low rates (DRL) performance

scientific article

Nigral 6-hydroxydopamine lesion impairs performance in a lateralised choice reaction time task--impact of training and task parameters

scientific article published on 05 March 2014

Nigral grafts in animal models of Parkinson's disease. Is recovery beyond motor function possible?

scientific article published in January 2012

Nigral grafts in neonatal rats protect from aphagia induced by subsequent adult 6-OHDA lesions: the importance of striatal location

scientific article published on 01 January 1990

Nimodipine enhances growth and vascularization of neural grafts

scientific article published on 01 April 1989

Observing Huntington's Disease: the European Huntington's Disease Network's REGISTRY

scientific article

Operant Analysis of Fronto-striatal Function in Rodents

Operant-based instrumental learning for analysis of genetically modified models of Huntington's disease.

scientific article published on 24 March 2011

Optimising Golgi-Cox staining for use with perfusion-fixed brain tissue validated in the zQ175 mouse model of Huntington's disease

scientific article published on 9 October 2015

Optimising plasticity: environmental and training associated factors in transplant-mediated brain repair.

scientific article

Outcome of cell suspension allografts in a patient with Huntington's disease

scientific article published on 25 October 2018

Pharmacological modulation of amphetamine-induced dyskinesia in transplanted hemi-parkinsonian rats.

scientific article published on 18 June 2012

Phosphorylation of Parkin at serine 65 is essential for its activation

scientific article published on 07 November 2018

Porcine neural xenografts in the immunocompetent rat: immune response following grafting of expanded neural precursor cells

scientific article published in January 2001

Potential cellular and regenerative approaches for the treatment of Parkinson's disease.

scientific article published in October 2008

Pre-treatment with dopamine agonists influence L-dopa mediated rotations without affecting abnormal involuntary movements in the 6-OHDA lesioned rat.

scientific article published on 29 April 2010

Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson's Disease

scientific article

Preface

Preface

Preface

Proactive interference effects on short-term memory in rats: I. Basic parameters and drug effects.

scientific article published in October 1990

Proactive interference effects on short-term memory in rats: II. Effects in young and aged rats.

scientific article published in October 1990

Profiles of motor and cognitive impairment in the transgenic rat model of Huntington's disease.

scientific article

Progressive striatal and cortical dopamine receptor dysfunction in Huntington's disease: a PET study.

scientific article published in May 2003

Prospects for new restorative and neuroprotective treatments in Parkinson's disease

scientific article (publication date: 24 June 1999)

Proteomic changes in the brains of Huntington's disease mouse models reflect pathology and implicate mitochondrial changes

scientific article published on 25 January 2011

Proximal movements compensate for distal forelimb movement impairments in a reach-to-eat task in Huntington's disease: new insights into motor impairments in a real-world skill

scientific article published on 5 November 2010

Re-examining the ontogeny of substantia nigra dopamine neurons

scientific article published in March 2006

Recovery of functional deficits following early donor age ventral mesencephalic grafts in a rat model of Parkinson's disease.

scientific article

Regulatory impairments following selective 6-OHDA lesions of the neostriatum

scientific article published on 01 February 1982

Regulatory impairments following selective kainic acid lesions of the neostriatum

scientific article published on 01 December 1980

Rehabilitation training in neural restitution.

scientific article published on 07 March 2017

Reinnervation of the denervated striatum by substantia nigra transplants: functional consequences as revealed by pharmacological and sensorimotor testing

scientific article published on 01 October 1980

Repair of the damaged brain. The Alfred Meyer Memorial Lecture 1998.

scientific article

Reprogramming the diseased brain.

scientific article published in May 2017

Response disinhibition on a delayed matching to position task induced by amphetamine, nicotine and age

scientific article published on 01 January 1991

Reverse transcription of inserted DNA in a monkey gives us ANDi.

scientific article

Rewiring the Parkinsonian brain

scientific article published on 01 February 2002

Role of corticostriatal and nigrostriatal inputs in malonate-induced striatal toxicity.

scientific article

Rule learning, visuospatial function and motor performance in the Hdh(Q92) knock-in mouse model of Huntington's disease.

scientific article published on 13 May 2009

SMAD transcription factors are altered in cell models of HD and regulate HTT expression

scientific article

Selective cognitive impairment in the YAC128 Huntington's disease mouse.

scientific article

Selective discrimination learning impairments in mice expressing the human Huntington's disease mutation.

scientific article published in December 1999

Selective extra-dimensional set shifting deficit in a knock-in mouse model of Huntington's disease

scientific journal article

Selective immunolesioning of the basal forebrain cholinergic system disrupts short-term memory in rats.

scientific article

Selective lesioning of the cholinergic septo-hippocampal pathway does not disrupt spatial short-term memory: a comparison with the effects of fimbria-fornix lesions

scientific article

Sensorimotor impairments following localized kainic acid and 6-hydroxydopamine lesions of the neostriatum

scientific article published in September 1982

Septal transplants restore maze learning in rats with fornix-fimbria lesions

scientific article

Serotonin hyperinnervation after foetal nigra or raphe transplantation in the neostriatum of adult rats

scientific article

Sex and gender in Brain Research Bulletin ⬇️

scientific article published on May 15, 2003

Similar striatal gene expression profiles in the striatum of the YAC128 and HdhQ150 mouse models of Huntington's disease are not reflected in mutant Huntingtin inclusion prevalence

scientific article published on 21 December 2015

Spatial learning and motor deficits in aged rats

scientific article published in January 1984

Spatially and temporally restricted chemoattractive and chemorepulsive cues direct the formation of the nigro-striatal circuit

scientific article published in February 2004

Special Issue: Trophic Factors, Neural Growth, and Transplantation in the CNS

scientific article published on 01 February 1996

Spontaneous and drug-induced rotation following localized 6-hydroxydopamine and kainic acid-induced lesions of the neostriatum

scientific article published in September 1982

Stem cell transplantation for Huntington's disease.

scientific article published on 8 January 2007

Striatal graft projections are influenced by donor cell type and not the immunogenic background.

scientific article

Striatal grafts alleviate bilateral striatal lesion deficits in operant delayed alternation in the rat.

scientific article

Striatal grafts alleviate deficits in response execution in a lateralised reaction time task.

scientific article published in December 1998

Striatal grafts in rats with unilateral neostriatal lesions--I. Ultrastructural evidence of afferent synaptic inputs from the host nigrostriatal pathway

scientific article

Striatal grafts in rats with unilateral neostriatal lesions--III. Recovery from dopamine-dependent motor asymmetry and deficits in skilled paw reaching

scientific article

Striatal lesions in the mouse disrupt acquisition and retention, but not implicit learning, in the SILT procedural motor learning task.

scientific article published on 20 September 2007

Striatal lesions produce distinctive impairments in reaction time performance in two different operant chambers

scientific article published in August 1998

Striatal neurons in striatal grafts are derived from both post-mitotic cells and dividing progenitors

scientific article published in February 2004

Striatal transplantation in a transgenic mouse model of Huntington's disease

scientific article published in November 1998

Subthalamic nucleus lesions induce deficits as well as benefits in the hemiparkinsonian rat.

scientific article published in August 1999

Subtle but progressive cognitive deficits in the female tgHD hemizygote rat as demonstrated by operant SILT performance.

scientific article

Surveying the literature from animal experiments.

scientific article published in April 2005

Survival and differentiation of rat and human epidermal growth factor-responsive precursor cells following grafting into the lesioned adult central nervous system

scientific article published in February 1996

Survival and functional restoration of human fetal ventral mesencephalon following transplantation in a rat model of Parkinson's disease

scientific article published on 7 September 2012

Survival of nigral grafts within the striatum of marmosets with 6-OHDA lesions depends critically on donor embryo age.

scientific article published in November 1997

Synaptic input and local output of dopaminergic neurons in grafts that functionally reinnervate the host neostriatum

scientific article published in January 1987

Synaptic relationships between cortical and dopaminergic inputs and intrinsic GABAergic systems within intrastriatal striatal grafts

scientific article

Systematic and detailed analysis of behavioural tests in the rat middle cerebral artery occlusion model of stroke: Tests for long-term assessment.

scientific article published on 17 June 2016

Targeting delivery in Parkinson's disease

scientific article published on 13 June 2016

Targeting the subthalamic nucleus in the treatment of Parkinson's disease

scientific article published in August 1998

Technical factors that influence neural transplant safety in Huntington's disease.

scientific article published on 16 September 2010

Tests to assess motor phenotype in mice: a user's guide

scientific article

The "staircase test": a measure of independent forelimb reaching and grasping abilities in rats

scientific article published in February 1991

The 12th International Symposium on Neural Transplantation and Restoration

scientific article published in December 2013

The 6-OHDA mouse model of Parkinson's disease - Terminal striatal lesions provide a superior measure of neuronal loss and replacement than median forebrain bundle lesions

scientific article published on 2 April 2015

The Amphetamine Induced Rotation Test: A Re-Assessment of Its Use as a Tool to Monitor Motor Impairment and Functional Recovery in Rodent Models of Parkinson's Disease

scientific article published on 01 January 2019

The Corridor Task: a simple test of lateralised response selection sensitive to unilateral dopamine deafferentation and graft-derived dopamine replacement in the striatum.

scientific article published on 15 September 2005

The Effect of Tissue Preparation and Donor Age on Striatal Graft Morphology in the Mouse.

scientific article

The T cell oncogene Tal2 is necessary for normal development of the mouse brain

scientific journal article

The biology and behaviour of intracerebral adrenal transplants in animals and man.

scientific article published in April 1993

The contributions of motor cortex, nigrostriatal dopamine and caudate-putamen to skilled forelimb use in the rat.

scientific article

The corridor task: striatal lesion effects and graft-mediated recovery in a model of Huntington's disease

scientific article

The development of intracerebral cell-suspension implants is influenced by the grafting medium.

scientific article published in November 1998

The effect of additional noradrenergic and serotonergic depletion on a lateralised choice reaction time task in rats with nigral 6-OHDA lesions.

scientific article published on 12 December 2013

The effect of microglia on embryonic dopaminergic neuronal survival in vitro: diffusible signals from neurons and glia change microglia from neurotoxic to neuroprotective.

scientific article published in May 1999

The effects of bilateral striatal lesions on the acquisition of an operant test of short term memory.

scientific article published in October 1995

The effects of donor stage on the survival and function of embryonic striatal grafts in the adult rat brain. I. Morphological characteristics

scientific article published in August 1997

The effects of donor stage on the survival and function of embryonic striatal grafts in the adult rat brain. II. Correlation between positron emission tomography and reaching behaviour.

scientific article published in August 1997

The effects of excitotoxic lesions of the nucleus accumbens on a matching to position task

scientific article published in December 1991

The effects of lateralized training on spontaneous forelimb preference, lesion deficits, and graft-mediated functional recovery after unilateral striatal lesions in rats.

scientific article

The expression of Huntingtin-associated protein (HAP1) mRNA in developing, adult and ageing rat CNS: implications for Huntington's disease neuropathology

scientific article published in May 1998

The failure of axon regeneration in the CNS is not absolute.

scientific article

The influence of environment and experience on neural grafts.

scientific article

The influence of excitotoxic basal ganglia lesions on motor performance in the common marmoset.

scientific article published in July 2000

The intrinsic specification of gamma-aminobutyric acid type A receptor alpha6 subunit gene expression in cerebellar granule cells

scientific article published in June 1999

The lateral neostriatum is necessary for compensatory ingestive behaviour after intravascular dehydration in female rats.

scientific article

The localization of an antibody to STEP in embryonic striatal tissue grafts

scientific article published on 01 December 1994

The localization of cholecystokinin mRNA in embryonic striatal tissue grafts: further evidence for the presence of non-striatal cells.

scientific article published in June 1993

The long-term safety and efficacy of bilateral transplantation of human fetal striatal tissue in patients with mild to moderate Huntington's disease

scientific article (publication date: June 2013)

The morphological development of neurons derived from EGF- and FGF-2-driven human CNS precursors depends on their site of integration in the neonatal rat brain

scientific article published in July 2000

The neurotrophin NT4/5, but not NT3, enhances the efficacy of nigral grafts in a rat model of Parkinson's disease

scientific article

The placement of a striatal ibotenic acid lesion affects skilled forelimb use and the direction of drug-induced rotation.

scientific article published in January 1996

The potential for circuit reconstruction by expanded neural precursor cells explored through porcine xenografts in a rat model of Parkinson's disease

scientific article

The problem of antipsychotic treatment for functional imaging in Huntington's disease: receptor binding, gene expression and locomotor activity after sub-chronic administration and wash-out of haloperidol in the rat.

scientific article published in January 2000

The release of excitatory amino acids, dopamine, and potassium following transplantation of embryonic mesencephalic dopaminergic grafts to the rat striatum, and their effects on dopaminergic neuronal survival in vitro

scientific article

The search for genetic mouse models of prodromal Parkinson's disease.

scientific article published on 14 July 2012

The staircase test of skilled reaching in mice

scientific article published in January 2001

The survival of neural precursor cell grafts is influenced by in vitro expansion.

scientific article

The use of rodent skilled reaching as a translational model for investigating brain damage and disease.

scientific article published on 30 December 2011

The utilisation of operant delayed matching and non-matching to position for probing cognitive flexibility and working memory in mouse models of Huntington's disease

scientific article published on 27 August 2015

Three-dimensional motion analysis of postural adjustments during over-ground locomotion in a rat model of Parkinson's disease

scientific article published on 03 February 2011

Time course of choice reaction time deficits in the Hdh(Q92) knock-in mouse model of Huntington's disease in the operant serial implicit learning task (SILT).

scientific article published on 12 February 2008

Tissue transplants for PD.

scientific article

Towards a protocol for the preparation and delivery of striatal tissue for clinical trials of transplantation in Huntington's disease.

scientific article

Training specificity, graft development and graft-mediated functional recovery in a rodent model of Huntington's disease.

scientific article

Translation of cell therapies to the clinic: characteristics of cell suspensions in large-diameter injection cannulae

scientific article published on 13 November 2014

Transplantation in the rat model of Parkinson's disease: ectopic versus homotopic graft placement.

scientific article

Transplantation of embryonic dopamine neurons: what we know from rats ⬇️

scientific article published on April 1, 1991

Transplantation of expanded neural precursor cells from the developing pig ventral mesencephalon in a rat model of Parkinson's disease

scientific article

Transplantation site influences the phenotypic differentiation of dopamine neurons in ventral mesencephalic grafts in Parkinsonian rats

scientific article published on 25 January 2017

Transplanted dopaminergic neurons: more or less?

scientific article published in May 2001

Transplanted hNT cells ("LBS neurons") in a rat model of huntington's disease: good survival, incomplete differentiation, and limited functional recovery.

scientific article published on January 2004

Trophic mechanisms are not enough

scientific article published on 01 July 1989

Ultrastructural neuropathology in murine trisomy 16 hippocampal grafts.

scientific article published in February 1993

Unilateral 6-OHDA lesions induce lateralised deficits in a 'skinner box' operant choice reaction time task in rats

scientific article

Unilateral dopamine lesions in neonatal, weanling and adult rats: comparison of rotation and reaching deficits.

scientific article published in October 1992

Unilateral lesions of the dorsal striatum in rats disrupt responding in egocentric space

scientific article published in November 1997

Unilateral lesions of the medial agranular cortex impair responding on a lateralised reaction time task.

scientific article published in June 2000

Unilateral nigrostriatal 6-hydroxydopamine lesions in mice II: predicting l-DOPA-induced dyskinesia

scientific article

Unilateral striatal lesions impair response execution on a lateralised choice reaction time task.

scientific article published in September 1997

Using Actiwatch to monitor circadian rhythm disturbance in Huntington' disease: A cautionary note

scientific article published on 13 January 2016

Validating the use of M4-BAC-GFP mice as tissue donors in cell replacement therapies in a rodent model of Huntington's disease

scientific article published on 3 February 2011

Validation of the l-dopa-induced dyskinesia in the 6-OHDA model and evaluation of the effects of selective dopamine receptor agonists and antagonists

scientific article

What helps can also hinder: A dissociation in the acute effect of levodopa treatment on motor and cognitive functions

scientific article published on 21 January 2013

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