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List of works by Stephen C. West

A new class of ultrafine anaphase bridges generated by homologous recombination

scientific article published on 25 September 2018

ATP-dependent branch migration of Holliday junctions promoted by the RuvA and RuvB proteins of E. coli.

scientific article published in June 1992

Aberrant chromosome morphology in human cells defective for Holliday junction resolution

scientific article published on 13 March 2011

Action of RecBCD enzyme on Holliday structures made by RecA.

scientific article published in October 1991

Actions of aprataxin in multiple DNA repair pathways

scientific article

Activation of RuvC Holliday junction resolvase in vitro

scientific article published on July 1994

Amino terminal sequence of the recA protein of Escherichia coli

scientific article published on October 1979

An assay for in vitro recombination between duplex DNA molecules

scientific article published on 01 January 1994

Architecture and DNA Recognition Elements of the Fanconi Anemia FANCM-FAAP24 Complex

scientific article published on 3 September 2013

BRCA2 BRC motifs bind RAD51-DNA filaments

scientific article

BRCA2-dependent and independent formation of RAD51 nuclear foci

scientific article

BRCA2: a universal recombinase regulator.

scientific article

Binding of double-strand breaks in DNA by human Rad52 protein

scientific article published on April 1999

Biochemical properties of RuvBD113N: a mutation in helicase motif II of the RuvB hexamer affects DNA binding and ATPase activities.

scientific article published in September 1997

Biological roles of the Escherichia coli RuvA, RuvB and RuvC proteins revealed

scientific article published on October 1, 1992

Branch migration and Holliday junction resolution catalyzed by activities from mammalian cells

scientific article

Branch migration during homologous recombination: assembly of a RuvAB-Holliday junction complex in vitro.

scientific article

Branch migration of Holliday junctions promoted by the Escherichia coli RuvA and RuvB proteins. I. Comparison of RuvAB- and RuvB-mediated reactions.

scientific article

Branch migration of Holliday junctions promoted by the Escherichia coli RuvA and RuvB proteins. II. Interaction of RuvB with DNA.

scientific article

CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair

scientific article

Can recA protein promote homologous pairing between duplex regions of DNA?

scientific article published on January 1982

Cell-cycle kinases coordinate the resolution of recombination intermediates with chromosome segregation

scientific article published on 27 June 2013

Cleavage specificity of bacteriophage T4 endonuclease VII and bacteriophage T7 endonuclease I on synthetic branch migratable holliday junctions

scientific article published on 01 April 1990

Cloning, overexpression, purification, and characterization of the Escherichia coli RuvC Holliday junction resolvase.

scientific article

Complex formation by the human RAD51C and XRCC3 recombination repair proteins

scientific article

Conformational changes modulate the activity of human RAD51 protein

scientific article published in April 2004

Coordinated actions of RuvABC in Holliday junction processing 1 1Edited by J. Karn

Coordinated actions of SLX1-SLX4 and MUS81-EME1 for Holliday junction resolution in human cells

scientific article published on 26 September 2013

Cross-links between Fanconi anaemia and BRCA2

scientific article published on 01 February 2003

DNA end-joining catalyzed by human cell-free extracts

scientific article

DNA helicases get physical.

scientific article

DNA helicases: new breeds of translocating motors and molecular pumps

scientific article published on July 1996

DNA interstrand crosslink repair and cancer ⬇️

scientific article published on June 24, 2011

DNA repair synthesis facilitates RAD52-mediated second-end capture during DSB repair

scientific article

DNA-dependent SUMO modification of PARP-1

scientific article published on 18 July 2013

Defective DNA repair and neurodegenerative disease

scientific article

Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways

scientific article

Dissociation of RecA filaments from duplex DNA by the RuvA and RuvB DNA repair proteins

scientific article published in October 1994

Distinct functions of BRCA1 and BRCA2 in double-strand break repair

scientific article

Distinct roles of Mus81, Yen1, Slx1-Slx4, and Rad1 nucleases in the repair of replication-born double-strand breaks by sister chromatid exchange

scientific article

Distribution of the Rad51 recombinase in human and mouse spermatocytes ⬇️

scientific article published on September 1, 1997

Domain structure and dynamics in the helical filaments formed by RecA and Rad51 on DNA.

scientific article

Double-strand break repair in human cells.

scientific article

Dual control of Yen1 nuclease activity and cellular localization by Cdk and Cdc14 prevents genome instability

scientific article published on 13 March 2014

Duplex-duplex interactions catalyzed by recA protein allow strand exchanges to pass double-strand breaks in DNA ⬇️

scientific article published on June 1, 1984

Effect of DNA topology on Holliday junction resolution by Escherichia coli RuvC and bacteriophage T7 endonuclease I.

scientific article

Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells

scientific article

Enzymatic formation and resolution of Holliday junctions in vitro.

scientific article

Enzymatic formation of biparental figure-eight molecules from plasmid DNA and their resolution in E. coli

scientific article published on 01 March 1983

Enzymes and molecular mechanisms of genetic recombination

scientific article published on January 1, 1992

Escherichia coli RuvBL268S: a mutant RuvB protein that exhibits wild-type activities in vitro but confers a UV-sensitive ruv phenotype in vivo.

scientific article

Exchanging partners: recombination in E. coli.

scientific article published on January 1996

FANCM and FAAP24 function in ATR-mediated checkpoint signaling independently of the Fanconi anemia core complex

scientific article

FANCM connects the genome instability disorders Bloom's Syndrome and Fanconi Anemia

scientific article

Formation and resolution of recombination intermediates by E. coli RecA and RuvC proteins.

scientific article

Formation of RuvABC-Holliday junction complexes in vitro

scientific article

Formation of a RuvAB-Holliday Junction Complex in Vitro

scientific article published on 01 July 1993

Formation, translocation and resolution of Holliday junctions during homologous genetic recombination

scientific article published on January 1995

Functional interactions between the holliday junction resolvase and the branch migration motor of Escherichia coli.

scientific article

Functional interactions of Mycobacterium leprae RuvA with Escherichia coli RuvB and RuvC on holliday junctions 1 1Edited by M. Yaniv

scholarly article by Judit Arenas-Licea et al published August 2000 in Journal of Molecular Biology

Functional overlap between the structure-specific nucleases Yen1 and Mus81-Mms4 for DNA-damage repair in S. cerevisiae

scientific article

Genetic recombination in E. coli: RuvC protein cleaves Holliday junctions at resolution hotspots in vitro

scientific article published in December 1994

Genetic recombination in Escherichia coli: Holliday junctions made by RecA protein are resolved by fractionated cell-free extracts

scientific article

Genetic recombination: recA protein promotes homologous pairing between duplex DNA molecules without strand unwinding

scientific article published on August 1981

Gross chromosomal rearrangements and genetic exchange between nonhomologous chromosomes following BRCA2 inactivation.

scientific article

Happy Hollidays: 40th anniversary of the Holliday junction

scientific article

Helicase-defective RuvB D113E promotes RuvAB-mediated branch migration in Vitro 1 1Edited by J. Karn

article published in 1999

Heteroduplex formation by human Rad51 protein: effects of DNA end-structure, hRP-A and hRad52.

scientific article published in August 1999

Heteroduplex formation by recA protein: polarity of strand exchanges ⬇️

scientific article published on October 1, 1981

Hexameric rings of Escherichia coli RuvB protein. Cooperative assembly, processivity and ATPase activity.

scientific article

Holliday Junction Branch Migration and Resolution Assays

scientific article published on 01 January 2004

Holliday junction processing enzymes as guardians of genome stability

scientific article

Holliday junction resolution in human cells: two junction endonucleases with distinct substrate specificities

scientific article

Holliday junction resolution: regulation in space and time

scientific article published on 24 April 2014

Holliday junction resolvases

scientific article published on 02 September 2014

Holliday junctions cleaved by Rad1?

scientific article published in Nature

Homologous pairing and the formation of nascent synaptic intermediates between regions of duplex DNA by RecA protein

scientific article published on 01 March 1989

Homologous pairing can occur before DNA strand separation in general genetic recombination

scientific article published in Nature

Human DNA polymerase eta promotes DNA synthesis from strand invasion intermediates of homologous recombination

scientific article published on December 2005

Human Dmc1 protein binds DNA as an octameric ring.

scientific article published on September 1999

Human RECQ5beta, a protein with DNA helicase and strand-annealing activities in a single polypeptide

scientific article

Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro

scientific article

Identification and characterization of the human mus81-eme1 endonuclease

scientific article

Identification and purification of two distinct complexes containing the five RAD51 paralogs ⬇️

scientific article published on December 15, 2001

Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM.

scientific article published in February 2007

Identification of Holliday junction resolvases from humans and yeast

scientific article

Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2

scientific article

Identification of protein X of Escherichia coli as the recA+/tif+ gene product

scientific article

In vitro reconstitution of the late steps of genetic recombination in E. coli.

scientific article

InTERTpreting telomerase structure and function

scientific article

Induction of protein synthesis in Escherichia coli following UV- or gamma-irradiation, mitomycin C treatment or tif Expression

scientific article

Initiation of genetic recombination: homologous pairing between duplex DNA molecules promoted by recA protein

scientific article

Interaction of a four-way junction in DNA with T4 endonuclease VII.

scientific article published in June 1990

Interactions between human BRCA2 protein and the meiosis-specific recombinase DMC1

scientific article

Involvement of human polynucleotide kinase in double-strand break repair by non-homologous end joining

scientific article

Keeping homologous recombination in check

scientific article

Late steps in genetic recombination: branch migration and Holliday junction resolution by RuvA, RuvB, and RuvC proteins

scientific article published on 01 January 1993

MUS81-EME2 promotes replication fork restart

scientific article published on 9 May 2014

Mechanism of E. coli RecA protein directed strand exchanges in post-replication repair of DNA

scientific article published in Nature

Mechanism of Holliday junction resolution by the human GEN1 protein

scientific article

Molecular cross-talk among chromosome fragility syndromes

scientific article published in June 2004

Molecular mechanism of DNA deadenylation by the neurological disease protein aprataxin

scientific article

Molecular mechanisms of general genetic recombination: the DNA-binding sites of RecA protein

scientific article published on 01 January 1984

Molecular views of recombination proteins and their control

scientific article (publication date: June 2003)

More complexity to the Bloom's syndrome complex

scientific article

Nonhomologous end joining and V(D)J recombination require an additional factor

scientific article

P. mirabilis RecA protein catalyses cleavage of E. coli LexA protein and the ? repressor in vitro

scientific article published on 01 January 1984

Plasma Membrane Association but Not Midzone Recruitment of RhoGEF ECT2 Is Essential for Cytokinesis

scientific article (publication date: 6 December 2016)

Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins

scientific article

Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1

scientific article

Processing of Holliday junctions by RuvABC--an overview

scientific article published on July 1994

Processing of Holliday junctions by the Escherichia coli RuvA, RuvB, RuvC and RecG proteins

scientific article

Processing of recombination intermediates by the RuvABC proteins

scientific article published on January 1997

Protein-DNA interactions in genetic recombination

scientific article published on January 1988

Purification and characterization of the human Rad51 protein, an analogue of E. coli RecA

scientific article

Purification and properties of the RuvA and RuvB proteins of Escherichia coli

scientific article published in October 1992

Purification and properties of the recA protein of Proteus mirabilis. Comparison with Escherichia coli recA protein; specificity of interaction with single strand binding protein

scientific article published in Journal of Biological Chemistry

Purification of human Rad51 protein by selective spermidine precipitation.

scientific article published in August 1997

RAD51 localization and activation following DNA damage

scientific article

RAD51C deficiency in mice results in early prophase I arrest in males and sister chromatid separation at metaphase II in females

scientific journal article

RAD51C is required for Holliday junction processing in mammalian cells

scientific article

RIDDLE immunodeficiency syndrome is linked to defects in 53BP1-mediated DNA damage signaling

scholarly article

RTEL-1 enforces meiotic crossover interference and homeostasis

scientific article

RTEL1 maintains genomic stability by suppressing homologous recombination

scientific article

Recombination at mammalian telomeres: an alternative mechanism for telomere protection and elongation

scientific article

Recombination genes and proteins

scientific article published on April 1994

Recombination initiation: easy as A, B, C, D... chi?

scientific article published on December 1997

Regulation of recombinational repair by the familial breast cancer susceptibility protein BRCA2.

scientific article published in November 2006

Regulatory control of the resolution of DNA recombination intermediates during meiosis and mitosis

scientific article

Relaxing and unwinding on Holliday: DNA helicase-mediated branch migration

scientific article published on November 1995

Repeat expansions confer WRN dependence in microsatellite-unstable cancers

scientific article published on 30 September 2020

Resolution of Holliday junctions by RuvC resolvase: cleavage specificity and DNA distortion.

scientific article published on September 1993

Resolution of Holliday junctions in genetic recombination: RuvC protein nicks DNA at the point of strand exchange

scientific article published on October 1996

Resolution of Holliday junctions in vitro requires the Escherichia coli ruvC gene product ⬇️

scientific article published on July 15, 1991

Resolution of Recombination Intermediates: Mechanisms and Regulation

scientific article published on 14 September 2015

Resolution of model Holliday junctions by yeast endonuclease: effect of DNA structure and sequence.

scientific article published on January 1989

Resolution of model holliday junctions by yeast endonuclease is dependent upon homologous DNA sequences

article

Resolution of single and double Holliday junction recombination intermediates by GEN1.

scientific article published on 03 January 2017

Resolution of synthetic Holliday junctions in DNA by an endonuclease activity from calf thymus

scientific article published on September 1990

Role of BRCA2 in control of the RAD51 recombination and DNA repair protein.

scientific article

Role of RAD51C and XRCC3 in genetic recombination and DNA repair

scientific article published on 17 November 2006

Role of RecA protein spiral filaments in genetic recombination

scientific article published in Nature

Role of RuvA in branch migration reactions catalyzed by the RuvA and RuvB proteins of Escherichia coli.

scientific article

Role of SSB protein in RecA promoted branch migration reactions

scientific article published on 01 January 1982

Role of mammalian RAD51L2 (RAD51C) in recombination and genetic stability

scientific article published on 23 March 2002

Role of the Rad1 and Rad10 proteins in nucleotide excision repair and recombination.

scientific article

Role of the human RAD51 protein in homologous recombination and double-stranded-break repair ⬇️

scientific article published on July 1, 1998

Roles of SLX1-SLX4, MUS81-EME1, and GEN1 in avoiding genome instability and mitotic catastrophe

scientific article published on May 2014

RuvA Gets X-Rayed on Holliday

scientific article published on 01 September 1998

RuvAB-mediated branch migration does not involve extensive DNA opening within the RuvB hexamer

scientific article

RuvC protein resolves Holliday junctions via cleavage of the continuous (noncrossover) strands.

scientific article

Senataxin, defective in the neurodegenerative disorder ataxia with oculomotor apraxia 2, lies at the interface of transcription and the DNA damage response

scientific article

Sequence-specificity of Holliday junction resolution: identification of RuvC mutants defective in metal binding and target site recognition.

scientific article published on August 1998

Sickle Cell Anemia Research and a Recombinant DNA Technique

scientific article

Single-stranded DNA-binding protein hSSB1 is critical for genomic stability

scientific article

Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose)

scientific article

Spatial control of the GEN1 Holliday junction resolvase ensures genome stability

scientific article published on 11 September 2014

Specific binding of cruciform DNA structures by a protein from human extracts

scientific article published on May 1988

Specific interaction of IP6 with human Ku70/80, the DNA-binding subunit of DNA-PK

scientific article published on April 2002

Specificity of binding to four-way junctions in DNA by bacteriophage T7 endonuclease I.

scientific article published on August 1990

Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2.

scientific article

Structural Analysis of the RuvC-Holliday Junction Complex Reveals and Unfolded Junction ⬇️

scientific article published on September 15, 1995

Structural and Mechanistic Analysis of the Slx1-Slx4 Endonuclease

scientific article

Structural and functional relationships of the XPF/MUS81 family of proteins

scientific article published on January 2008

Structure and mechanism of action of the BRCA2 breast cancer tumor suppressor

scientific article

Structure of a multisubunit complex that promotes DNA branch migration.

scientific article

Structure of the single-strand annealing domain of human RAD52 protein

scientific article

Substrate specificity of the Escherichia coli RuvC protein. Resolution of three- and four-stranded recombination intermediates.

scientific article

Substrate specificity of the MUS81-EME2 structure selective endonuclease

scientific article published on 25 December 2013

Synergistic actions of Rad51 and Rad52 in recombination and DNA repair ⬇️

scientific article published on January 22, 1998

Synthetic junctions as tools to identify and characterize Holliday junction resolvases

scientific article published in January 2006

T7 endonuclease I resolves Holliday junctions formed in vitro by RecA protein.

scientific article published on October 1990

TRF2 promotes, remodels and protects telomeric Holliday junctions

scientific article published on 05 February 2009

Targeted versus non-targeted DNA helicase activity of the RuvA and RuvB proteins of Escherichia coli.

scientific article

Telomere maintenance requires the RAD51D recombination/repair protein

scientific article

The Bloom's syndrome gene product promotes branch migration of holliday junctions

scientific article

The DNA translocase activity of FANCM protects stalled replication forks

scientific article published on 24 January 2012

The Escherichia coli RuvB branch migration protein forms double hexameric rings around DNA.

scientific article published on August 1994

The RuvABC proteins and Holliday junction processing in Escherichia coli

scientific article

The RuvC protein dimer resolves Holliday junctions by a dual incision mechanism that involves base-specific contacts

scientific article

The SMX DNA Repair Tri-nuclease

scientific article published on March 2017

The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA.

scientific article

The directionality of RuvAB-mediated branch migration: in vitro studies with three-armed junctions

scientific article

The efficiency of strand invasion by Escherichia coli RecA is dependent upon the length and polarity of ssDNA tails

scholarly article by Michael J McIlwraith & Stephen C. West published January 2001 in Journal of Molecular Biology

The human Holliday junction resolvase GEN1 rescues the meiotic phenotype of a Schizosaccharomyces pombe mus81 mutant

scientific article

The human Rad51 protein: polarity of strand transfer and stimulation by hRP-A ⬇️

scientific article published on September 1, 1997

The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates

scientific article

The processing of recombination intermediates: mechanistic insights from studies of bacterial proteins

scientific article

The search for a human Holliday junction resolvase

scientific article

Underwinding of DNA associated with duplex-duplex pairing by RecA protein.

scientific article

Unresolved recombination intermediates lead to ultra-fine anaphase bridges, chromosome breaks and aberrations

scientific article

Unusual stability of recombination intermediates made by Escherichia coli RecA protein.

scientific article

Unwinding of closed circular DNA by the Escherichia coli RuvA and RuvB recombination/repair proteins.

scientific article

Visualisation of human rad52 protein and its complexes with hRad51 and DNA.

scientific article published on December 1998

Visualization of recombination intermediates produced by RAD52-mediated single-strand annealing

scientific article

Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest

scientific article

XPG endonuclease makes the 3' incision in human DNA nucleotide excision repair

scientific article

XRCC3 and Rad51 modulate replication fork progression on damaged vertebrate chromosomes

scientific article published in April 2003

recA+-dependent inactivation of the lambda repressor in Escherichia coli lysogens by gamma-radiation and by tif expression

scientific article published in November 1975

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