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List of works by Stephen Busby

A comparison of the DNA bending activities of the DNA binding proteins CRP and TFIID.

scientific article

A cryptic promoter in the LEE1 regulatory region of enterohaemorrhagic Escherichia coli: promoter specificity in AT-rich gene regulatory regions.

scientific article

A novel promoter architecture for microaerobic activation by the anaerobic transcription factor FNR

scientific article published on 01 February 2001

A unified resource for transcriptional regulation in Escherichia coli K-12 incorporating high-throughput-generated binding data into RegulonDB version 10.0

scientific article published on 16 August 2018

Activating transcription in bacteria.

scientific article published on 15 June 2012

Activation of sigma 28-dependent transcription in Escherichia coli by the cyclic AMP receptor protein requires an unusual promoter organization.

scientific article published on 15 October 2009

Affinity isolation and I-DIRT mass spectrometric analysis of the Escherichia coli O157:H7 Sakai RNA polymerase complex.

scientific article

An FNR-type regulator controls the anaerobic expression of hyn hydrogenase in Thiocapsa roseopersicina.

scientific article published on April 2005

An HcpR homologue from Desulfovibrio desulfuricans and its possible role in nitrate reduction and nitrosative stress

scientific article published on 01 January 2011

Analysis of interactions between Activating Region 1 of Escherichia coli FNR protein and the C-terminal domain of the RNA polymerase alpha subunit: use of alanine scanning and suppression genetics.

scientific article

Analysis of mechanisms of activation and repression at bacterial promoters.

scientific article published on 24 October 2008

Architectural requirements for optimal activation by tandem CRP molecules at a class I CRP-dependent promoter

scientific article published on 01 April 2002

Assays for transcription factor activity

scientific article published on 01 January 2001

Association of nucleoid proteins with coding and non-coding segments of the Escherichia coli genome.

scientific article published on 08 September 2006

Autoregulation of the Escherichia coli melR promoter: repression involves four molecules of MelR.

scientific article published on 16 March 2008

Binding of the Escherichia coli MelR protein to the melAB promoter: orientation of MelR subunits and investigation of MelR-DNA contacts.

scientific article

Characterization of multiple promoters and transcript stability in the sacB-sacC gene cluster in Zymomonas mobilis.

scientific article published on 5 May 2009

Chromosome position effects on gene expression in Escherichia coli K-12.

scientific article published on 10 September 2014

Comparison of promoter activities in Escherichia coli and Pseudomonas aeruginosa: use of a new broad-host-range promoter-probe plasmid

scientific article published on 01 January 1990

Competition between NarL-dependent activation and Fis-dependent repression controls expression from the Escherichia coli yeaR and ogt promoters.

scientific article published on 13 May 2009

DNA barcodes for rapid, whole genome, single-molecule analyses

scientific article published on 01 July 2019

Definition of nitrite and nitrate response elements at the anaerobically inducible Escherichia coli nirB promoter: interactions between FNR and NarL.

scientific article published in January 1993

Direct methods for studying transcription regulatory proteins and RNA polymerase in bacteria.

scientific article published on 15 September 2009

Double locking of an Escherichia coli promoter by two repressors prevents premature colicin expression and cell lysis.

scientific article published on 13 August 2012

Effects of nucleoid-associated proteins on bacterial chromosome structure and gene expression

scientific article published on October 13, 2010

Effects of substitutions at position 180 in the Escherichia coli RNA polymerase σ 70 subunit.

scientific article

Escherichia coli "TatExpress" strains export several g/L human growth hormone to the periplasm by the Tat pathway

scientific article published on 02 September 2019

Escherichia coli "TatExpress" strains super-secrete human growth hormone into the bacterial periplasm by the Tat pathway.

scientific article published on 26 August 2017

Exploitation of a chemical nuclease to investigate the location and orientation of the Escherichia coli RNA polymerase alpha subunit C-terminal domains at simple promoters that are activated by cyclic AMP receptor protein.

scientific article published on 6 October 2003

Genomic studies with Escherichia coli MelR protein: applications of chromatin immunoprecipitation and microarrays.

scientific article

Global regulators of transcription in Escherichia coli: mechanisms of action and methods for study.

scientific article published on January 2008

Host attachment and fluid shear are integrated into a mechanical signal regulating virulence in Escherichia coli O157:H7.

scientific article published on 13 April 2015

Identification and analysis of 'extended -10' promoters in Escherichia coli.

scientific article

Independent regulation of the divergent Escherichia coli nrfA and acsP1 promoters by a nucleoprotein assembly at a shared regulatory region.

scientific article published on February 2002

Interactions between activating region 3 of the Escherichia coli cyclic AMP receptor protein and region 4 of the RNA polymerase sigma(70) subunit: application of suppression genetics.

scientific article

Interconversion between bound and free conformations of LexA orchestrates the bacterial SOS response.

scientific article published on 16 May 2011

Investigations of the modular structure of bacterial promoters

scientific article published on 01 January 2006

Local and global regulation of transcription initiation in bacteria

scientific article

Location and dynamics of an active promoter in Escherichia coli K-12

scientific article published on January 1, 2012

Location and orientation of an activating region in the Escherichia coli transcription factor, FNR.

scientific article published on January 1994

Location and sequence of the promoter of the gene for the NADH-dependent nitrite reductase of Escherichia coli and its regulation by oxygen, the Fnr protein and nitrite.

scientific article published in August 1987

Location of the Escherichia coli RNA polymerase alpha subunit C-terminal domain at an FNR-dependent promoter: analysis using an artificial nuclease.

scientific article published in January 2004

Mass spectrometry of Escherichia coli RNA polymerase: interactions of the core enzyme with sigma70 and Rsd protein.

scientific article published in February 2004

Microarray analysis of the Ler regulon in enteropathogenic and enterohaemorrhagic Escherichia coli strains

scientific article published on 14 January 2014

Modulation of CRP-dependent transcription at the Escherichia coli acsP2 promoter by nucleoprotein complexes: anti-activation by the nucleoid proteins FIS and IHF.

scientific article published on January 2004

Mutational analysis of the Escherichia coli melR gene suggests a two-state concerted model to explain transcriptional activation and repression in the melibiose operon

scientific article published on May 2006

Mutational analysis of the nucleotide sequence at the FNR-dependent nirB promoter in Escherichia coli.

scientific article published on January 1989

Mutations that alter the ability of the Escherichia coli cyclic AMP receptor protein to activate transcription.

scientific article published on December 1990

Mutations that increase the activity of the promoter of the Escherichia coli melibiose operon improve the binding of MelR, a transcription activator triggered by melibiose.

scientific article published on June 2000

New targets for the cyclic AMP receptor protein in the Escherichia coli K-12 genome.

scientific article published on 30 June 2007

Organization and architecture of AggR-dependent promoters from enteroaggregative Escherichia coli

scientific article published on 18 December 2018

Oxygen and contact with human intestinal epithelium independently stimulate virulence gene expression in enteroaggregative Escherichia coli

article

Point mutations in the DNA- and cNMP-binding domains of the homologue of the cAMP receptor protein (CRP) in Mycobacterium bovis BCG: implications for the inactivation of a global regulator and strain attenuation.

scientific article

Positioning of region 4 of the Escherichia coli RNA polymerase sigma(70) subunit by a transcription activator.

scientific article

RNA polymerase supply and flux through the lac operon in Escherichia coli.

scientific article published on November 2016

Recruitment of RNA polymerase to Class II CRP-dependent promoters is improved by a second upstream-bound CRP molecule

scientific article published on 01 December 2006

Redefining fundamental concepts of transcription initiation in bacteria

scientific article published on 14 July 2020

Regulation of RamA by RamR in Salmonella enterica serovar Typhimurium: isolation of a RamR superrepressor

scientific article published on 4 September 2012

Regulation of acetyl coenzyme A synthetase in Escherichia coli.

scientific article published in August 2000

Regulation of nrf operon expression in pathogenic enteric bacteria: sequence divergence reveals new regulatory complexity

scientific article published on 17 February 2017

Regulation, sensory domains and roles of two Desulfovibrio desulfuricans ATCC27774 Crp family transcription factors, HcpR1 and HcpR2, in response to nitrosative stress.

scientific article

Repression by Cyclic AMP Receptor Protein at a Distance

scientific article published on September 11, 2012

Repression of the Escherichia coli melR promoter by MelR: evidence that efficient repression requires the formation of a repression loop.

scientific article published on April 2000

Requirement for two copies of RNA polymerase alpha subunit C-terminal domain for synergistic transcription activation at complex bacterial promoters

scientific article published on October 2002

Role of activating region 1 of Escherichia coli FNR protein in transcription activation at class II promoters.

scientific article

Role of the RNA polymerase alpha subunits in CII-dependent activation of the bacteriophage lambda pE promoter: identification of important residues and positioning of the alpha C-terminal domains.

scientific article published on 3 February 2004

Roles of effectors in XylS-dependent transcription activation: intramolecular domain derepression and DNA binding

scientific article published on 22 February 2008

Selective repression by Fis and H-NS at the Escherichia coli dps promoter.

scientific article

SepL resembles an aberrant effector in binding to a class 1 type III secretion chaperone and carrying an N-terminal secretion signal

scientific article published on 10 September 2010

Serine substitution for cysteine residues in levansucrase selectively abolishes levan forming activity

scientific article published on October 1, 2003

Silencing of DNase Colicin E8 Gene Expression by a Complex Nucleoprotein Assembly Ensures Timely Colicin Induction.

scientific article published on 26 June 2015

Spacing requirements for Class I transcription activation in bacteria are set by promoter elements

scientific article

Studies of the distribution of Escherichia coli cAMP-receptor protein and RNA polymerase along the E. coli chromosome.

scientific article

Suppression of FNR-dependent transcription activation at the Escherichia coli nir promoter by Fis, IHF and H-NS: modulation of transcription initiation by a complex nucleo-protein assembly.

scientific article

Targets for the MalI repressor at the divergent Escherichia coli K-12 malX-malI promoters

scientific article published on 20 January 2010

The Escherichia coli K-12 MntR miniregulon includes dps, which encodes the major stationary-phase DNA-binding protein

scientific article

The Escherichia coli K-12 NarL and NarP proteins insulate the nrf promoter from the effects of integration host factor.

scientific article published on 25 August 2006

The Escherichia coli RutR transcription factor binds at targets within genes as well as intergenic regions.

scientific article

The PAR promoter expression system: Modified lac promoters for controlled recombinant protein production in Escherichia coli

scientific article published in 2021

The bacterial LexA transcriptional repressor.

scientific article

The new bacteriology

scientific article published on November 2016

The nirB promoter of Escherichia coli: location of nucleotide sequences essential for regulation by oxygen, the FNR protein and nitrite.

scientific article

The role of two surface exposed loops in transcription activation by the Escherichia coli CRP and FNR proteins.

scientific article published on December 1991

Tracking Low-Copy Transcription Factors in Living Bacteria: The Case of the lac Repressor.

scientific article published in April 2017

Transcription activation at the Escherichia coli melAB promoter: interactions of MelR with its DNA target site and with domain 4 of the RNA polymerase sigma subunit.

scientific article published in March 2004

Transcription activation by FNR: evidence for a functional activating region 2.

scientific article published on November 2002

Transcription activation in bacteria: ancient and modern

scientific article published on 18 February 2019

Transcription factor distribution in Escherichia coli: studies with FNR protein.

scientific article published on 12 December 2006

Transcription initiation in the Escherichia coli K-12 malI-malX intergenic region and the role of the cyclic AMP receptor protein.

scientific article published in November 2008

Transcription of the plasmid-encoded toxin gene from enteroaggregative Escherichia coli is regulated by a novel co-activation mechanism involving CRP and Fis.

scientific article

Transcription regulation by tandem-bound FNR at Escherichia coli promoters.

scientific article

Two DNA sites for MelR in the same orientation are sufficient for optimal MelR-dependent repression at theEscherichia colimelRpromoter

scientific article published on November 8, 2012

UP element-dependent transcription at the Escherichia coli rrnB P1 promoter: positional requirements and role of the RNA polymerase alpha subunit linker.

scientific article

Unusual organization, complexity and redundancy at the Escherichia coli hcp-hcr operon promoter

scientific article published on 01 August 2010