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List of works by Martin F. Bachmann

A Single Monoclonal Antibody against the Peanut Allergen Ara h 2 Protects against Systemic and Local Peanut Allergy

scientific article published on 10 March 2020

A VLP-based vaccine against interleukin-1α protects mice from atherosclerosis

scientific article published on 28 January 2013

A VLP-based vaccine targeting domain III of the West Nile virus E protein protects from lethal infection in mice

scientific article

A molecular assembly system that renders antigens of choice highly repetitive for induction of protective B cell responses

scientific article

A novel recycling mechanism of native IgE-antigen complexes in human B cells facilitates transfer of antigen to dendritic cells for antigen presentation.

scientific article published on 23 October 2017

A second vaccine revolution for the new epidemics of the 21st century

scientific article published on 26 September 2006

A therapeutic vaccine for nicotine dependence: preclinical efficacy, and Phase I safety and immunogenicity

scientific article

A vaccine against Alzheimer`s disease: anything left but faith?

scientific article published on 17 December 2018

A vaccine against nicotine for smoking cessation: a randomized controlled trial

scientific article

A vaccine for hypertension based on virus-like particles: preclinical efficacy and phase I safety and immunogenicity

scientific article published in January 2007

A virus-like particle-based anti-nerve growth factor vaccine reduces inflammatory hyperalgesia: potential long-term therapy for chronic pain

scientific article

A virus-like particle-based vaccine selectively targeting soluble TNF-alpha protects from arthritis without inducing reactivation of latent tuberculosis

scientific article

Accuracy of serological testing for SARS-CoV-2 antibodies: first results of a large mixed-method evaluation study

scientific article published on 30 September 2020

Active immunisation targeting nerve growth factor attenuates chronic pain behaviour in murine osteoarthritis.

scientific article published on 12 March 2019

Active immunization with IL-1 displayed on virus-like particles protects from autoimmune arthritis

scientific article published in March 2008

Active immunotherapy for chronic diseases

scientific article published on 14 February 2013

Active vaccination against Interleukin-5 as long-term treatment for insect bite hypersensitivity in horses

scientific article published on 25 November 2018

Adjusted Particle Size Eliminates the Need of Linkage of Antigen and Adjuvants for Appropriated T Cell Responses in Virus-Like Particle-Based Vaccines

scientific article published on 06 March 2017

Allergen-specific immunotherapy: regulatory T cells or allergen-specific IgG?

scientific article published on 01 August 2010

Allergens displayed on virus-like particles are highly immunogenic but fail to activate human mast cells.

scientific article published on 8 August 2017

Alveolar macrophages and lung dendritic cells sense RNA and drive mucosal IgA responses

scientific article

An unexpected protective role of low affinity allergen-specific IgG via the inhibitory receptor FcγRIIb.

scientific article

Averting inflammation by targeting the cytokine environment

scientific article

Bacterially produced recombinant influenza vaccines based on virus-like particles

scientific article

Balancing protective immunity and immunopathology

scientific article

Biosensor-based selective detection of Zika virus specific antibodies in infected individuals.

scientific article published in May 2018

Blocking IL-1α but not IL-1β increases susceptibility to chronic Mycobacterium tuberculosis infection in mice

scientific article published on 18 November 2010

CCL19 and CCL21 induce a potent proinflammatory differentiation program in licensed dendritic cells

scientific journal article

CD23 provides a noninflammatory pathway for IgE-allergen complexes

scientific article published on 19 August 2019

COVID-19: Mechanisms of Vaccination and Immunity

scientific article published on 22 July 2020

Carrier induced epitopic suppression of antibody responses induced by virus-like particles is a dynamic phenomenon caused by carrier-specific antibodies

scientific article published on 20 March 2010

Chemokines: more than just road signs

scientific article published on 01 February 2006

Combined vaccination against IL-5 and eotaxin blocks eosinophilia in mice

scientific article

Complement component C3 promotes T-cell priming and lung migration to control acute influenza virus infection

scientific article published in April 2002

Complement receptors regulate differentiation of bone marrow plasma cell precursors expressing transcription factors Blimp-1 and XBP-1

scientific article published on 14 March 2005

Correction to: Vaccination with nanoparticles combined with micro-adjuvants protects against cancer

scientific article published on 23 May 2019

Correction: Zika Virus-Derived E-DIII Protein Displayed on Immunologically Optimized VLPs Induces Neutralizing Antibodies without Causing Enhancement of Dengue Virus Infection. Vaccines 2019, 7, 72

scientific article published on 20 February 2020

CpG oligodeoxynucleotides block human immunodeficiency virus type 1 replication in human lymphoid tissue infected ex vivo

scientific article

Critical role for activation of antigen-presenting cells in priming of cytotoxic T cell responses after vaccination with virus-like particles

scientific article published on March 2002

Cross-presentation of virus-like particles by skin-derived CD8(-) dendritic cells: a dispensable role for TAP.

scientific article published in March 2002

Cutting edge: IL-21 and TLR signaling regulate germinal center responses in a B cell-intrinsic manner

scientific article published on 05 April 2010

Cutting edge: identification of E-cadherin as a ligand for the murine killer cell lectin-like receptor G1.

scientific article published on February 2006

Cutting edge: limited specialization of dendritic cell subsets for MHC class II-associated presentation of viral particles

scientific article published on 30 November 2009

DOPS Adjuvant Confers Enhanced Protection against Malaria for VLP-TRAP Based Vaccines

scientific article

Delivering adjuvants and antigens in separate nanoparticles eliminates the need of physical linkage for effective vaccination.

scientific article published on 28 February 2017

Der p 1 peptide on virus-like particles is safe and highly immunogenic in healthy adults

scientific article published on 27 April 2006

Designing recombinant vaccines with viral properties: a rational approach to more effective vaccines

scientific article published on March 2007

Detecting circulating antibodies by controlled surface modification with specific target proteins: Application to malaria

scientific article published on 15 January 2017

Development of a COVID-19 vaccine based on the receptor binding domain displayed on virus-like particles

scientific article published on 08 May 2020

Development of a Plasmodium vivax malaria vaccine for clinical applications using transgenic parasites, virus-like particles and recombinant viruses

scientific article published on 22 September 2014

Development of an Interleukin-1β Vaccine in Patients with Type 2 Diabetes

scientific article published on 21 December 2015

Displaying Fel d1 on virus-like particles prevents reactogenicity despite greatly enhanced immunogenicity: a novel therapy for cat allergy

scientific article published on 10 August 2009

Distinct T helper cell dependence of memory B-cell proliferation versus plasma cell differentiation.

scientific article published on 9 November 2016

Early Transcriptional Signature in Dendritic Cells and the Induction of Protective T Cell Responses Upon Immunization With VLPs Containing TLR Ligands-A Role for CCL2

scientific article published on 02 August 2019

Effect of immunisation against angiotensin II with CYT006-AngQb on ambulatory blood pressure: a double-blind, randomised, placebo-controlled phase IIa study

scientific article

Efficient homologous prime-boost strategies for T cell vaccination based on virus-like particles

scientific article

Efficient induction of mucosal and systemic immune responses by virus-like particles administered intranasally: implications for vaccine design

scientific article published in January 2008

Enhanced apoptotic activity of a structurally optimized form of galectin-1.

scientific article

Enhanced neutralizing antibody titers and Th1 polarization from a novel Escherichia coli derived pandemic influenza vaccine.

scientific article

Evaluation of Plasmodium vivax Cell-Traversal Protein for Ookinetes and Sporozoites as a Preerythrocytic P. vivax Vaccine

scientific article published on 08 February 2017

Exploiting viral properties for the rational design of modern vaccines

scientific article

Follicular and marginal zone B cells fail to cross-present MHC class I-restricted epitopes derived from viral particles

scientific article published in May 2009

Glycan-specific IgG anti-IgE autoantibodies are protective against allergic anaphylaxis in a murine model

scientific article published on 09 December 2020

Harnessing Nanoparticles for Immunomodulation and Vaccines

scientific article published on 14 February 2017

HealVax

scientific article published on 24 May 2018

Heterogeneous antibody repertoire of marginal zone B cells specific for virus-like particles

scientific article published on 12 January 2007

Hybrid Sindbis/Epstein-Barr virus episomal expression vector for inducible production of proteins

scientific article published on August 2005

IL-17A/F-signaling does not contribute to the initial phase of mucosal inflammation triggered by S. Typhimurium

scientific article (publication date: 23 November 2010)

IL-21 induces death of marginal zone B cells during chronic inflammation

scientific article published on 08 September 2010

Identification of Ly-6K as a novel marker for mouse plasma cells

scientific journal article

Immunization of Cats against Fel d 1 Results in Reduced Allergic Symptoms of Owners

scientific article published on 06 March 2020

Immunization of cats to induce neutralizing antibodies against Fel d 1, the major feline allergen in human subjects

scientific article published on 02 May 2019

Immunization strategies for Clostridium difficile infections

scientific article published on April 2012

Immunodrugs: breaking B- but not T-cell tolerance with therapeutic anticytokine vaccines

scientific article published on July 2010

Immunodrugs: therapeutic VLP-based vaccines for chronic diseases

scientific article published on January 2009

Immunotherapy of type-1 allergies with virus-like particles and CpG-motifs

scientific article

Incorporation of tetanus-epitope into virus-like particles achieves vaccine responses even in older recipients in models of psoriasis, Alzheimer's and cat allergy

scientific article published on 23 October 2017

Induction of Human T-cell and Cytokine Responses Following Vaccination with a Novel Influenza Vaccine

scientific article published in Scientific Reports

Influenza A vaccine based on the extracellular domain of M2: weak protection mediated via antibody-dependent NK cell activity

scientific article published in May 2004

Innate immunity mediates follicular transport of particulate but not soluble protein antigen

scientific article published on 16 March 2012

Innate immunity together with duration of antigen persistence regulate effector T cell induction

scientific article published on 01 July 2003

Innate signaling regulates cross-priming at the level of DC licensing and not antigen presentation

scientific article published on 01 January 2010

Innate signals compensate for the absence of PKC-{theta} during in vivo CD8(+) T cell effector and memory responses

scientific article

Interaction of Viral Capsid-Derived Virus-Like Particles (VLPs) with the Innate Immune System

scholarly article by Mona O Mohsen et al published 2 July 2018 in Vaccines

Interleukin 31 in insect bite hypersensitivity-Alleviating clinical symptoms by active vaccination against itch

scientific article published on 09 December 2019

Interleukin-1 is responsible for acute lung immunopathology but increases survival of respiratory influenza virus infection

scientific article

Intralymphatic immunotherapy: time interval between injections is essential

scientific article published on 15 January 2014

Intranasal administration of a VLP-based vaccine induces neutralizing antibodies against SARS-CoV-2 and variants of concern

scientific article published on 11 April 2022

Is The Allergen Really Needed in Allergy Immunotherapy?

scientific article published on January 2015

Isolation of human monoclonal antibodies by mammalian cell display

scientific article

Limited in vivo reactivity of polyclonal effector cytotoxic T cells towards altered peptide ligands

scientific article published on 08 April 2005

Loading of MHC class I and II presentation pathways by exogenous antigens: a quantitative in vivo comparison

scientific article published in May 2004

Low-affinity B cells transport viral particles from the lung to the spleen to initiate antibody responses

scientific article

Maintenance of memory CTL responses by T helper cells and CD40-CD40 ligand: antibodies provide the key.

scientific article published in February 2004

Major findings and recent advances in virus-like particle (VLP)-based vaccines

scientific article published on 5 September 2017

Mechanisms of allergen-specific desensitization

scientific article published on 10 July 2010

Memory and effector CD8 T-cell responses after nanoparticle vaccination of melanoma patients

scientific article

Microcrystalline Tyrosine (MCT®): A Depot Adjuvant in Licensed Allergy Immunotherapy Offers New Opportunities in Malaria

scientific article published on 27 September 2017

Nano-particle vaccination combined with TLR-7 and -9 ligands triggers memory and effector CD8⁺ T-cell responses in melanoma patients

scientific article published on 28 August 2012

Nanoassembly routes stimulate conflicting antibody quantity and quality for transmission-blocking malaria vaccines

scientific article

Nanoparticles target distinct dendritic cell populations according to their size

scientific article published in May 2008

Neutralization of IL-17 by active vaccination inhibits IL-23-dependent autoimmune myocarditis

scientific article published on 01 November 2006

Noninfectious Disease Vaccines

Nonmethylated CG motifs packaged into virus-like particles induce protective cytotoxic T cell responses in the absence of systemic side effects

scientific article published in February 2004

Nrf2 is essential for cholesterol crystal-induced inflammasome activation and exacerbation of atherosclerosis

scientific article published on 08 June 2011

Osteopontin is not required for the development of Th1 responses and viral immunity

scientific article published on 01 November 2005

Plasmodium vivax malaria vaccines: why are we where we are?

scientific article

Plug-and-Display: decoration of Virus-Like Particles via isopeptide bonds for modular immunization

scientific article

Potent T cell agonism mediated by a very rapid TCR/pMHC interaction

scientific article

Preclinical development of a vaccine against oligomeric alpha-synuclein based on virus-like particles

scientific article published on 10 August 2017

Preclinical efficacy and safety of an anti-IL-1β vaccine for the treatment of type 2 diabetes

scientific article

Prophylactic and therapeutic activity of fully human monoclonal antibodies directed against influenza A M2 protein

scientific article

Protection against osteoporosis by active immunization with TRANCE/RANKL displayed on virus-like particles

scientific article

Protective effect of a germline, IL-17-neutralizing antibody in murine models of autoimmune inflammatory disease

scientific article published on 23 January 2015

Questions for biotechs.

scientific article published in July 2010

RNA and Toll-Like Receptor 7 License the Generation of Superior Secondary Plasma Cells at Multiple Levels in a B Cell Intrinsic Fashion

Rapid functional cloning of cell adhesion molecules.

scientific article

Rapid response of marginal zone B cells to viral particles

scientific article published in October 2004

Regulation of IgG antibody responses by epitope density and CD21-mediated costimulation

scientific article published on 01 November 2002

Regulation of memory antibody levels: the role of persisting antigen versus plasma cell life span

scientific article published on 01 January 2007

Reply to 'Blood pressure vaccine shot down by safety concerns'

scientific article published on 01 March 2006

Role of IgM antibodies versus B cells in influenza virus-specific immunity

scientific article published in August 2002

Role of Toll-like receptors in costimulating cytotoxic T cell responses

scientific article

Safety Profile of a Virus-Like Particle-Based Vaccine Targeting Self-Protein Interleukin-5 in Horses

scientific article published on 09 May 2020

Safety and immunogenicity of a virus-like particle pandemic influenza A (H1N1) 2009 vaccine: results from a double-blinded, randomized Phase I clinical trial in healthy Asian volunteers.

scientific article

Secretory phospholipase A2-IID is an effector molecule of CD4+CD25+ regulatory T cells

scientific journal article

Selective utilization of Toll-like receptor and MyD88 signaling in B cells for enhancement of the antiviral germinal center response

scientific article published on 25 February 2011

Shaping Modern Vaccines: Adjuvant Systems Using MicroCrystalline Tyrosine (MCT<sup>®</sup>)

scientific article published on 24 November 2020

Special Issue "Virus-Like Particle Vaccines"

scientific article published on 10 August 2020

Strategies to Prevent SARS-CoV-2-Mediated Eosinophilic Disease in Association with COVID-19 Vaccination and Infection

scientific article published on 16 June 2020

T cell-dependent and -independent IgA responses: role of TLR signalling

scientific article published on January 2010

TLR9 signaling in B cells determines class switch recombination to IgG2a

scientific article published on 01 February 2007

Targeting Mutated Plus Germline Epitopes Confers Pre-clinical Efficacy of an Instantly Formulated Cancer Nano-Vaccine.

scientific article published on 15 May 2019

Targeting osteoporosis and rheumatoid arthritis by active vaccination against RANKL

scientific article published on 01 January 2007

Taurine: Energy drink for T cells ⬇️

scientific article published on April 1, 2012

The 3Ds in virus-like particle based-vaccines: "Design, Delivery and Dynamics"

scientific article published on 30 May 2020

The 5th virus-like particle and nano-particle vaccines (VLPNPV) conference

scientific article published on 13 December 2018

The Prospects of an Active Vaccine Against Asthma Targeting IL-5

scientific article published on 24 October 2018

The coming of age of virus-like particle vaccines

scientific article published on May 2008

The human membrane cofactor CD46 is a receptor for species B adenovirus serotype 3

scientific article published in May 2004

The next generation virus‐like particle platform for the treatment of peanut allergy

scientific article published in 2023

The novel TLR-9 agonist QbG10 shows clinical efficacy in persistent allergic asthma

scientific article published on 4 February 2013

The second-generation active Aβ immunotherapy CAD106 reduces amyloid accumulation in APP transgenic mice while minimizing potential side effects.

scientific article published in June 2011

The thioredoxin-1 and glutathione/glutaredoxin-1 systems redundantly fuel murine B-cell development and responses

scientific article published on 01 March 2019

Therapeutic silence of pleiotrophin by targeted delivery of siRNA and its effect on the inhibition of tumor growth and metastasis

scientific article

Therapeutic vaccination for chronic diseases: a new class of drugs in sight

scientific article published on January 2004

Therapeutic vaccination to block receptor-ligand interactions

scientific article

Therapeutic vaccines for chronic diseases: successes and technical challenges

scientific article published on October 2011

Therapeutic vaccines for nicotine dependence.

scientific article

Treating insect-bite hypersensitivity in horses with active vaccination against IL-5.

scientific article published on 28 March 2018

Type of RNA Packed in VLPs Impacts IgG Class Switching-Implications for an Influenza Vaccine Design

scientific article published on 04 June 2019

Universal vaccine against influenza virus: linking TLR signaling to anti-viral protection

scientific article published in April 2012

VSIG4, a B7 family-related protein, is a negative regulator of T cell activation

scientific journal article

Vaccination Against Amyloidogenic Aggregates in Pancreatic Islets Prevents Development of Type 2 Diabetes Mellitus

scientific article published on 02 March 2020

Vaccination against Allergy: A Paradigm Shift?

scientific article published on 13 February 2020

Vaccination against Alzheimer disease: an update on future strategies

scientific article published on 17 February 2014

Vaccination against GIP for the treatment of obesity

scientific article

Vaccination against IL-17 suppresses autoimmune arthritis and encephalomyelitis

scientific article published on 01 November 2006

Vaccination against IL-31 for the treatment of atopic dermatitis in dogs

scientific article published on 04 April 2018

Vaccination against nerve growth factor is an effective pain treatment in murine osteoarthritis

Vaccination against nicotine: an emerging therapy for tobacco dependence

scientific article published on November 2007

Vaccination with nanoparticles combined with micro-adjuvants protects against cancer

scientific article published on 26 April 2019

Vaccine against peanut allergy based on engineered virus-like particles displaying single major peanut allergens

scientific article published on 19 December 2019

Vaccine delivery: a matter of size, geometry, kinetics and molecular patterns

scientific article published on 15 October 2010

Vaccines against non-communicable diseases

scientific article published on 24 March 2010

Versatile virus-like particle carrier for epitope based vaccines

scientific article (publication date: 23 March 2010)

Virus-Like Particle (VLP) Plus Microcrystalline Tyrosine (MCT) Adjuvants Enhance Vaccine Efficacy Improving T and B Cell Immunogenicity and Protection against Plasmodium berghei/vivax

scientific article

Virus-Specific Secondary Plasma Cells Produce Elevated Levels of High-Avidity Antibodies but Are Functionally Short Lived

scientific article published on 06 August 2019

Virus-induced humoral immunity: on how B cell responses are initiated

scientific article published on June 2013

Virus-like particles (VLP) in prophylaxis and immunotherapy of allergic diseases.

scientific article published on 9 July 2018

Virus-like particles as a modular system for novel vaccines

scientific article

Virus-like particles as carriers for T-cell epitopes: limited inhibition of T-cell priming by carrier-specific antibodies

scientific article published on January 2005

Virus-like particles for vaccination against cancer

scientific article published on 27 August 2019

Virus-like particles induce robust human T-helper cell responses

scientific article

Zika Virus-Derived E-DIII Protein Displayed on Immunologically Optimized VLPs Induces Neutralizing Antibodies without Causing Enhancement of Dengue Virus Infection

scientific article published on 23 July 2019

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