List of works - Khalid Mohammed Khan

1-[(4'-Chlorophenyl) carbonyl-4-(aryl) thiosemicarbazide derivatives as potent urease inhibitors: Synthesis, in vitro and in silico studies

scientific article published on 23 May 2018

2'-Aryl and 4'-arylidene substituted pyrazolones: As potential α-amylase inhibitors

scientific article published on 21 September 2018

2-Arylquinazolin-4(3H)-ones: A new class of α-glucosidase inhibitors.

scientific article published on 29 October 2015

2-Arylquinazolin-4(3H)-ones: A novel class of thymidine phosphorylase inhibitors.

scientific article published on 29 October 2015

3,4-Dimethoxybenzohydrazide derivatives as antiulcer: Molecular modeling and density functional studies.

scientific article published on 7 October 2017

4-Arylamino-6-nitroquinazolines: Synthesis and their activities against neglected disease leishmaniasis.

scientific article published on 14 November 2015

5-Bromo-2-aryl benzimidazole derivatives as non-cytotoxic potential dual inhibitors of α-glucosidase and urease enzymes.

scientific article

A new glycotoxins inhibitor attenuates insulin resistance in liver and fat cells.

scientific article

Acridine-based (thio)semicarbazones and hydrazones: Synthesis, in vitro urease inhibition, molecular docking and in-silico ADME evaluation

scientific article published on 22 September 2018

Anthranilic Acid Derivatives: Novel Inhibitors of Protein Glycation and the Associated Oxidative Stress in the Hepatocytes.

scientific article published on 20 October 2017

Benzimidazole derivatives protect against cytokine-induced apoptosis in pancreatic β-Cells

scientific article published on 22 August 2015

Benzylidine indane-1,3-diones: As novel urease inhibitors; synthesis, in vitro, and in silico studies

scientific article published on 19 September 2018

Biology-Oriented Synthesis (BIOS) of Piperine Derivatives and their Comparative Analgesic and Antiinflammatory Activities.

scientific article published on 22 June 2017

Biology-oriented drug synthesis (BIODS), in vitro urease inhibitory activity, and in silico study of S-naproxen derivatives

scientific article published on 11 October 2018

Biology-oriented drug synthesis (BIODS): In vitro β-glucuronidase inhibitory and in silico studies on 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl aryl carboxylate derivatives.

scientific article published on 14 November 2016

Carbohydrazones as new class of carbonic anhydrase inhibitors: Synthesis, kinetics, and ligand docking studies.

scientific article published on 30 March 2017

Chelation-Assisted Copper-Mediated Direct Acetylamination of 2-Arylpyridine C-H Bonds with Cyanate Salts

scientific article published on 27 June 2016

Coumarin sulfonates: As potential leads for ROS inhibition

scientific article published on 19 September 2016

Coumarin sulfonates: New alkaline phosphatase inhibitors; in vitro and in silico studies.

scientific article

Crystal structure and Hirshfeld surface analysis of 1-(4-bromo-phen-yl)-2-{[5-(pyridin-3-yl)-1,3,4-oxa-diazol-2-yl]sulfan-yl}ethan-1-one

scientific article published on 31 March 2017

Crystal structure and Hirshfeld surface analysis of 1-(4-chloro-phen-yl)-2-{[5-(4-chloro-phen-yl)-1,3,4-oxa-diazol-2-yl]sulfan-yl}ethanone.

scientific article published on 17 March 2017

Crystal structure of 6-amino-4-(3-bromo-4-meth-oxy-phen-yl)-3-methyl-2,4-di-hydro-pyrano[2,3-c]pyrazole-5-carbo-nitrile dimethyl sulfoxide monosolvate.

scientific article published on 6 June 2015

Derivatives of 6-Nitrobenzimidazole Inhibit Fructose-Mediated Protein Glycation and Intracellular Reactive Oxygen Species Production.

scientific article published on 16 February 2017

Development of microwave assisted spectrophotometric method for the determination of glucose

scientific article published on 07 August 2015

Diclofenac 1,3,4-Oxadiazole Derivatives; Biology-Oriented Drug Synthesis (BIODS) in Search of Better Non-Steroidal, Non-Acid Antiinflammatory Agents

scientific article published on 21 March 2018

Dihydropyrimidones: As novel class of β-glucuronidase inhibitors.

scientific article published on 4 June 2016

Efficient Double Suzuki Cross-Coupling Reactions of 2,5-Dibromo-3-hexylthiophene: Anti-Tumor, Haemolytic, Anti-Thrombolytic and Biofilm Inhibition Studies.

scientific article published on 27 July 2016

Evaluation of 2-indolcarbohydrazones as potent α-glucosidase inhibitors, in silico studies and DFT based stereochemical predictions.

scientific article published on 10 September 2015

Facile dimethyl amino group triggered cyclic sulfonamides synthesis and evaluation as alkaline phosphatase inhibitors

scientific article published on 18 January 2017

Hybrid benzothiazole analogs as antiurease agent: Synthesis and molecular docking studies

scientific article published on 24 March 2016

Hydrazinyl arylthiazole based pyridine scaffolds: Synthesis, structural characterization, in vitro α-glucosidase inhibitory activity, and in silico studies.

scientific article published on 26 June 2017

In silico binding analysis and SAR elucidations of newly designed benzopyrazine analogs as potent inhibitors of thymidine phosphorylase.

scientific article published on 25 July 2016

Insulinotropic action of 2, 4-dinitroanilino-benzoic acid through the attenuation of pancreatic beta-cell lesions in diabetic rats.

scientific article published on 15 June 2017

Modification of Bischler-Möhlau indole derivatives through palladium catalyzed Suzuki reaction as effective cholinesterase inhibitors, their kinetic and molecular docking studies

scientific article published on 17 November 2017

Molecular hybridization conceded exceptionally potent quinolinyl-oxadiazole hybrids through phenyl linked thiosemicarbazide antileishmanial scaffolds: In silico validation and SAR studies

scientific article published on 19 February 2017

New Bis-Pyrazolones as Potential Leads for ROS Inhibition; Environment Friendly Green Synthesis, Structural Characterization, and In Vitro Studies.

scientific article published on 12 January 2018

New Hybrid Hydrazinyl Thiazole Substituted Chromones: As Potential α-Amylase Inhibitors and Radical (DPPH & ABTS) Scavengers

scientific article published on 5 December 2017

New indole based hybrid oxadiazole scaffolds with N-substituted acetamides: As potent anti-diabetic agents

scientific article published on 18 August 2018

New isatin derivative inhibits neurodegeneration by restoring insulin signaling in brain.

scientific article published on 13 January 2017

Novel acridine-based thiosemicarbazones as 'turn-on' chemosensors for selective recognition of fluoride anion: a spectroscopic and theoretical study

scientific article published on 04 July 2018

One-pot synthesis of tetrazole-1,2,5,6-tetrahydronicotinonitriles and cholinesterase inhibition: Probing the plausible reaction mechanism via computational studies.

scientific article

Oxindole based oxadiazole hybrid analogs: Novel α-glucosidase inhibitors

scientific article published on 2 December 2017

Palladium-catalyzed regioselective benzylation-annulation of pyridine N-oxides with toluene derivatives via multiple C-H bond activations: benzylation versus arylation

scientific article published on 21 January 2015

Quinazoline and quinazolinone as important medicinal scaffolds: a comparative patent review (2011-2016).

scientific article published on 25 January 2018

ROS Inhibitory Activity and Cytotoxicity Evaluation of Benzoyl, Acetyl, Alkyl Ester, and Sulfonate Ester Substituted Coumarin Derivatives

scientific article published on 26 August 2019

Schiff bases in medicinal chemistry: a patent review (2010-2015).

scientific article

Small molecules as activators in medicinal chemistry (2000-2016).

scientific article published on 4 July 2017

Syntheses of new 3-thiazolyl coumarin derivatives, in vitro α-glucosidase inhibitory activity, and molecular modeling studies

scientific article published on 24 June 2016

Synthesis and Characterization of Thiocarbohydrazones and their Inhibitory Potential Against Ignored Disease Leishmaniasis

scientific article published on 14 January 2018

Synthesis and in silico studies of novel sulfonamides having oxadiazole ring: As β-glucuronidase inhibitors.

scientific article

Synthesis and in vitro urease inhibitory activity of benzohydrazide derivatives, in silico and kinetic studies

scientific article published on 10 October 2018

Synthesis and molecular modelling studies of phenyl linked oxadiazole-phenylhydrazone hybrids as potent antileishmanial agents.

scientific article

Synthesis of 4-substituted ethers of benzophenone and their antileishmanial activities.

scientific article

Synthesis of 6-chloro-2-Aryl-1H-imidazo[4,5-b]pyridine derivatives: Antidiabetic, antioxidant, β-glucuronidase inhibiton and their molecular docking studies

scientific article published on 01 February 2016

Synthesis of Bis-indolylmethane sulfonohydrazides derivatives as potent α-Glucosidase inhibitors

scientific article published on 02 June 2018

Synthesis of indole analogs as potent β-glucuronidase inhibitors.

scientific article published on 7 May 2017

Synthesis of new oxadiazole derivatives as α-glucosidase inhibitors

scientific article published on 02 July 2015

Synthesis of novel benzohydrazone-oxadiazole hybrids as β-glucuronidase inhibitors and molecular modeling studies

scientific article published on 26 October 2015

Synthesis of novel bisindolylmethanes: New carbonic anhydrase II inhibitors, docking, and 3D pharmacophore studies.

scientific article published on 25 July 2016

Synthesis of novel inhibitors of α-glucosidase based on the benzothiazole skeleton containing benzohydrazide moiety and their molecular docking studies

scientific article published on 9 January 2015

Synthesis of piperazine sulfonamide analogs as diabetic-II inhibitors and their molecular docking study

scientific article published on 12 October 2017

Synthesis, biological evaluation, and docking studies of novel thiourea derivatives of bisindolylmethane as carbonic anhydrase II inhibitor

scientific article published on 05 August 2015

Synthesis, in vitro [Formula: see text]-glucosidase inhibitory activity, and in silico study of (E)-thiosemicarbazones and (E)-2-(2-(arylmethylene)hydrazinyl)-4-arylthiazole derivatives

scientific article published on 29 May 2018

Synthesis, in vitro urease inhibitory activity, and molecular docking studies of thiourea and urea derivatives

scientific article published on 05 June 2018

Synthesis, in vitro α-glucosidase inhibitory activity and molecular docking studies of new thiazole derivatives

scientific article published on 24 August 2016

Synthesis, in vitro α-glucosidase inhibitory potential and molecular docking study of thiadiazole analogs

scientific article published on 20 March 2018

Synthesis, in vitro β-glucuronidase inhibitory activity and in silico studies of novel (E)-4-Aryl-2-(2-(pyren-1-ylmethylene)hydrazinyl)thiazoles.

scientific article published on 31 December 2016

Synthesis, in vitro β-glucuronidase inhibitory potential and molecular docking studies of quinolines

scientific article published on 24 August 2017

Synthesis, molecular docking and xanthine oxidase inhibitory activity of 5-aryl-1H-tetrazoles

scientific article published on 01 May 2018

Synthesis, molecular docking and α-glucosidase inhibition of 5-aryl-2-(6'-nitrobenzofuran-2'-yl)-1,3,4-oxadiazoles

scientific article published on 26 April 2016

Synthesis, molecular docking study and in vitro thymidine phosphorylase inhibitory potential of oxadiazole derivatives

scientific article published on 07 March 2018

Synthesis, α-glucosidase inhibition and molecular docking study of coumarin based derivatives

scientific article published on 17 February 2018

Synthesis, α-glucosidase inhibitory activity and in silico study of tris-indole hybrid scaffold with oxadiazole ring: As potential leads for the management of type-II diabetes mellitus.

scientific article

Synthesis, α-glucosidase inhibitory, cytotoxicity and docking studies of 2-aryl-7-methylbenzimidazoles

scientific article published on 13 February 2016

Synthesis,In vitroand Docking Studies of New Flavone Ethers asα-Glucosidase Inhibitors

scientific article published on 13 November 2015

Synthetic indole Mannich bases: Their ability to modulate in vitro cellular immunity.

scientific article published on 8 May 2015

The immunomodulation potential of the synthetic derivatives of benzothiazoles: Implications in immune system disorders through in vitro and in silico studies.

scientific article published on 19 November 2015

Thiadiazole derivatives as New Class of β-glucuronidase inhibitors.

scientific article published on 10 March 2016

Xanthine Oxidase Inhibitory and Molecular Docking Studies on Pyrimidones

scientific article published on 29 November 2017

List of works by Khalid Mohammed Khan

1-[(4'-Chlorophenyl) carbonyl-4-(aryl) thiosemicarbazide derivatives as potent urease inhibitors: Synthesis, in vitro and in silico studies

2'-Aryl and 4'-arylidene substituted pyrazolones: As potential α-amylase inhibitors

2-Arylquinazolin-4(3H)-ones: A new class of α-glucosidase inhibitors.

2-Arylquinazolin-4(3H)-ones: A novel class of thymidine phosphorylase inhibitors.

3,4-Dimethoxybenzohydrazide derivatives as antiulcer: Molecular modeling and density functional studies.

4-Arylamino-6-nitroquinazolines: Synthesis and their activities against neglected disease leishmaniasis.

5-Bromo-2-aryl benzimidazole derivatives as non-cytotoxic potential dual inhibitors of α-glucosidase and urease enzymes.

A new glycotoxins inhibitor attenuates insulin resistance in liver and fat cells.

Acridine-based (thio)semicarbazones and hydrazones: Synthesis, in vitro urease inhibition, molecular docking and in-silico ADME evaluation

Anthranilic Acid Derivatives: Novel Inhibitors of Protein Glycation and the Associated Oxidative Stress in the Hepatocytes.

Benzimidazole derivatives protect against cytokine-induced apoptosis in pancreatic β-Cells

Benzylidine indane-1,3-diones: As novel urease inhibitors; synthesis, in vitro, and in silico studies

Biology-Oriented Synthesis (BIOS) of Piperine Derivatives and their Comparative Analgesic and Antiinflammatory Activities.

Biology-oriented drug synthesis (BIODS), in vitro urease inhibitory activity, and in silico study of S-naproxen derivatives

Biology-oriented drug synthesis (BIODS): In vitro β-glucuronidase inhibitory and in silico studies on 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl aryl carboxylate derivatives.

Carbohydrazones as new class of carbonic anhydrase inhibitors: Synthesis, kinetics, and ligand docking studies.

Chelation-Assisted Copper-Mediated Direct Acetylamination of 2-Arylpyridine C-H Bonds with Cyanate Salts

Coumarin sulfonates: As potential leads for ROS inhibition

Coumarin sulfonates: New alkaline phosphatase inhibitors; in vitro and in silico studies.

Crystal structure and Hirshfeld surface analysis of 1-(4-bromo-phen-yl)-2-{[5-(pyridin-3-yl)-1,3,4-oxa-diazol-2-yl]sulfan-yl}ethan-1-one

Crystal structure and Hirshfeld surface analysis of 1-(4-chloro-phen-yl)-2-{[5-(4-chloro-phen-yl)-1,3,4-oxa-diazol-2-yl]sulfan-yl}ethanone.

Crystal structure of 6-amino-4-(3-bromo-4-meth-oxy-phen-yl)-3-methyl-2,4-di-hydro-pyrano[2,3-c]pyrazole-5-carbo-nitrile dimethyl sulfoxide monosolvate.

Derivatives of 6-Nitrobenzimidazole Inhibit Fructose-Mediated Protein Glycation and Intracellular Reactive Oxygen Species Production.

Development of microwave assisted spectrophotometric method for the determination of glucose

Diclofenac 1,3,4-Oxadiazole Derivatives; Biology-Oriented Drug Synthesis (BIODS) in Search of Better Non-Steroidal, Non-Acid Antiinflammatory Agents

Dihydropyrimidones: As novel class of β-glucuronidase inhibitors.

Efficient Double Suzuki Cross-Coupling Reactions of 2,5-Dibromo-3-hexylthiophene: Anti-Tumor, Haemolytic, Anti-Thrombolytic and Biofilm Inhibition Studies.

Evaluation of 2-indolcarbohydrazones as potent α-glucosidase inhibitors, in silico studies and DFT based stereochemical predictions.

Facile dimethyl amino group triggered cyclic sulfonamides synthesis and evaluation as alkaline phosphatase inhibitors

Hybrid benzothiazole analogs as antiurease agent: Synthesis and molecular docking studies

Hydrazinyl arylthiazole based pyridine scaffolds: Synthesis, structural characterization, in vitro α-glucosidase inhibitory activity, and in silico studies.

In silico binding analysis and SAR elucidations of newly designed benzopyrazine analogs as potent inhibitors of thymidine phosphorylase.

Insulinotropic action of 2, 4-dinitroanilino-benzoic acid through the attenuation of pancreatic beta-cell lesions in diabetic rats.

Modification of Bischler-Möhlau indole derivatives through palladium catalyzed Suzuki reaction as effective cholinesterase inhibitors, their kinetic and molecular docking studies

Molecular hybridization conceded exceptionally potent quinolinyl-oxadiazole hybrids through phenyl linked thiosemicarbazide antileishmanial scaffolds: In silico validation and SAR studies

New Bis-Pyrazolones as Potential Leads for ROS Inhibition; Environment Friendly Green Synthesis, Structural Characterization, and In Vitro Studies.

New Hybrid Hydrazinyl Thiazole Substituted Chromones: As Potential α-Amylase Inhibitors and Radical (DPPH & ABTS) Scavengers

New indole based hybrid oxadiazole scaffolds with N-substituted acetamides: As potent anti-diabetic agents

New isatin derivative inhibits neurodegeneration by restoring insulin signaling in brain.

Novel acridine-based thiosemicarbazones as 'turn-on' chemosensors for selective recognition of fluoride anion: a spectroscopic and theoretical study

One-pot synthesis of tetrazole-1,2,5,6-tetrahydronicotinonitriles and cholinesterase inhibition: Probing the plausible reaction mechanism via computational studies.

Oxindole based oxadiazole hybrid analogs: Novel α-glucosidase inhibitors

Palladium-catalyzed regioselective benzylation-annulation of pyridine N-oxides with toluene derivatives via multiple C-H bond activations: benzylation versus arylation

Quinazoline and quinazolinone as important medicinal scaffolds: a comparative patent review (2011-2016).

ROS Inhibitory Activity and Cytotoxicity Evaluation of Benzoyl, Acetyl, Alkyl Ester, and Sulfonate Ester Substituted Coumarin Derivatives

Schiff bases in medicinal chemistry: a patent review (2010-2015).

Small molecules as activators in medicinal chemistry (2000-2016).

Syntheses of new 3-thiazolyl coumarin derivatives, in vitro α-glucosidase inhibitory activity, and molecular modeling studies

Synthesis and Characterization of Thiocarbohydrazones and their Inhibitory Potential Against Ignored Disease Leishmaniasis

Synthesis and in silico studies of novel sulfonamides having oxadiazole ring: As β-glucuronidase inhibitors.

Synthesis and in vitro urease inhibitory activity of benzohydrazide derivatives, in silico and kinetic studies

Synthesis and molecular modelling studies of phenyl linked oxadiazole-phenylhydrazone hybrids as potent antileishmanial agents.

Synthesis of 4-substituted ethers of benzophenone and their antileishmanial activities.

Synthesis of 6-chloro-2-Aryl-1H-imidazo[4,5-b]pyridine derivatives: Antidiabetic, antioxidant, β-glucuronidase inhibiton and their molecular docking studies

Synthesis of Bis-indolylmethane sulfonohydrazides derivatives as potent α-Glucosidase inhibitors

Synthesis of indole analogs as potent β-glucuronidase inhibitors.

Synthesis of new oxadiazole derivatives as α-glucosidase inhibitors

Synthesis of novel benzohydrazone-oxadiazole hybrids as β-glucuronidase inhibitors and molecular modeling studies

Synthesis of novel bisindolylmethanes: New carbonic anhydrase II inhibitors, docking, and 3D pharmacophore studies.

Synthesis of novel inhibitors of α-glucosidase based on the benzothiazole skeleton containing benzohydrazide moiety and their molecular docking studies

Synthesis of piperazine sulfonamide analogs as diabetic-II inhibitors and their molecular docking study

Synthesis, biological evaluation, and docking studies of novel thiourea derivatives of bisindolylmethane as carbonic anhydrase II inhibitor

Synthesis, in vitro [Formula: see text]-glucosidase inhibitory activity, and in silico study of (E)-thiosemicarbazones and (E)-2-(2-(arylmethylene)hydrazinyl)-4-arylthiazole derivatives

Synthesis, in vitro urease inhibitory activity, and molecular docking studies of thiourea and urea derivatives

Synthesis, in vitro α-glucosidase inhibitory activity and molecular docking studies of new thiazole derivatives

Synthesis, in vitro α-glucosidase inhibitory potential and molecular docking study of thiadiazole analogs

Synthesis, in vitro β-glucuronidase inhibitory activity and in silico studies of novel (E)-4-Aryl-2-(2-(pyren-1-ylmethylene)hydrazinyl)thiazoles.

Synthesis, in vitro β-glucuronidase inhibitory potential and molecular docking studies of quinolines

Synthesis, molecular docking and xanthine oxidase inhibitory activity of 5-aryl-1H-tetrazoles

Synthesis, molecular docking and α-glucosidase inhibition of 5-aryl-2-(6'-nitrobenzofuran-2'-yl)-1,3,4-oxadiazoles

Synthesis, molecular docking study and in vitro thymidine phosphorylase inhibitory potential of oxadiazole derivatives

Synthesis, α-glucosidase inhibition and molecular docking study of coumarin based derivatives

Synthesis, α-glucosidase inhibitory activity and in silico study of tris-indole hybrid scaffold with oxadiazole ring: As potential leads for the management of type-II diabetes mellitus.

Synthesis, α-glucosidase inhibitory, cytotoxicity and docking studies of 2-aryl-7-methylbenzimidazoles

Synthesis,In vitroand Docking Studies of New Flavone Ethers asα-Glucosidase Inhibitors

Synthetic indole Mannich bases: Their ability to modulate in vitro cellular immunity.

The immunomodulation potential of the synthetic derivatives of benzothiazoles: Implications in immune system disorders through in vitro and in silico studies.

Thiadiazole derivatives as New Class of β-glucuronidase inhibitors.

Xanthine Oxidase Inhibitory and Molecular Docking Studies on Pyrimidones