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List of works by Amit Kumar

(1)H NMR and FT-IR dataset based structural investigation of poly(amic acid)s and polyimides from 4,4'-diaminostilbene.

scientific article published on 09 February 2016

9-Demethoxy-medicarpin promotes peak bone mass achievement and has bone conserving effect in ovariectomized mice: Positively regulates osteoblast functions and suppresses osteoclastogenesis

scientific article published on 5 May 2015

A Crystal Structure of a Model of the Repeating r(CGG) Transcript Found in Fragile X Syndrome ⬇️

scientific article published on July 15, 2011

A Decade of Boon or Burden: What Has the CHIP Ever Done for Cellular Protein Quality Control Mechanism Implicated in Neurodegeneration and Aging?

scientific article

A combined experimental and theoretical (DFT and AIM) studies on synthesis, molecular structure, spectroscopic properties and multiple interactions analysis in a novel ethyl-4-[2-(thiocarbamoyl)hydrazinylidene]-3,5-dimethyl-1H-pyrrole-2-carboxylate

scientific article published on 12 April 2013

Acetylamine derivative of diospyrin, a plant-derived binaphthylquinonoid, inhibits human colon cancer growth in Nod-Scid mice.

scientific article published on 30 September 2014

An expedient route to imidazo[1,4]diazepin-7-ones via a post-Ugi gold-catalyzed heteroannulation

scientific article published on 01 April 2013

An unprecedented alteration in mode of action of IsCT resulting its translocation into bacterial cytoplasm and inhibition of macromolecular syntheses

scientific article

Analytical techniques for characterization of biological molecules - proteins and aptamers/oligonucleotides

scientific article published on 26 November 2018

Aptamers in the Therapeutics and Diagnostics Pipelines

scientific article published on 01 July 2018

Benzothiazole Derivative as a Novel Mycobacterium tuberculosis Shikimate Kinase Inhibitor: Identification and Elucidation of Its Allosteric Mode of Inhibition.

scientific article

Biosorption of Cd(II) on jatropha fruit coat and seed coat.

scientific article published on 7 June 2015

Characterization of G-Quadruplex Motifs in espB, espK, and cyp51 Genes of Mycobacterium tuberculosis as Potential Drug Targets

article

Characterization of highly conserved G-quadruplex motifs as potential drug targets in Streptococcus pneumoniae

scientific article published in Scientific Reports

Conformation and intramolecular relaxation dynamics of semiflexible randomly hyperbranched polymers.

scientific article

Coordination mode of pentadentate ligand derivative of 5-amino-1,3,4-thiadiazole-2-thiol with nickel(II) and copper(II) metal ions: synthesis, spectroscopic characterization, molecular modeling and fungicidal study

scientific article published on 6 October 2014

Design and characterization of short antimicrobial peptides using leucine zipper templates with selectivity towards microorganisms

scientific article published on 29 July 2014

Design, Synthesis, and Evaluation of the Kinase Inhibition Potential of Pyridylpyrimidinylaminophenyl Derivatives.

scientific article

Designing of a multi-epitope vaccine candidate against Nipah virus by in silico approach: a putative prophylactic solution for the deadly virus

scientific article published on 04 March 2020

Development and mechanistic insight into enhanced cytotoxic potential of hyaluronic acid conjugated nanoparticles in CD44 overexpressing cancer cells.

scientific article

Differential diagnosis of lung cancer, its metastasis and chronic obstructive pulmonary disease based on serum Vegf, Il-8 and MMP-9.

scientific article published on 4 November 2016

Differential roles of ATF-2 in survival and DNA repair contributing to radioresistance induced by autocrine soluble factors in A549 lung cancer cells.

scientific article

Discovery of a potent small molecule inhibiting Huntington's disease (HD) pathogenesis via targeting CAG repeats RNA and Poly Q protein

scientific article published on 14 November 2019

Effect of excluded volume on the rheology and transport dynamics of randomly hyperbranched polymers

scientific article published on 01 May 2015

Effect of proton and gamma irradiation on human lung carcinoma cells: Gene expression, cell cycle, cell death, epithelial-mesenchymal transition and cancer-stem cell trait as biological end points

scientific article published on 26 July 2015

Emerging methods for structural analysis of protein aggregation

scientific article published on 6 February 2017

Endothelial Dll4-Notch signaling in tumor microenvironment: is there any hidden therapeutic opportunity?

scientific article published on December 2013

Erratum to: Biosorption of Cd(II) on jatropha fruit coat and seed coat

scientific article published on 17 July 2015

Evidences for Piperine inhibiting cancer by targeting human G-quadruplex DNA sequences.

scientific article published on 20 December 2016

Experimental and theoretical (FT-IR, FT-Raman, UV-vis, NMR) spectroscopic analysis and first order hyperpolarizability studies of non-linear optical material: (2E)-3-[4-(methylsulfanyl) phenyl]-1-(4-nitrophenyl) prop-2-en-1-one using density functio

scientific article published on 8 April 2014

Exploring the Potential of Small Molecule-Based Therapeutic Approaches for Targeting Trinucleotide Repeat Disorders

scientific article published on 09 August 2019

G-Quadruplex-Forming DNA Aptamers Inhibit the DNA-Binding Function of HupB and Mycobacteriumtuberculosis Entry into Host Cells

scientific article published on 22 August 2018

G-quadruplex stabilization in the ions and maltose transporters inhibit Salmonella enterica growth and virulence

scientific article published on 27 June 2018

G4IPDB: A database for G-quadruplex structure forming nucleic acid interacting proteins.

scientific article published on December 2016

Generation and application of DNA aptamers against HspX for accurate diagnosis of tuberculous meningitis

scientific article published on 10 July 2018

Global temperature change potential of nitrogen use in agriculture: A 50-year assessment.

scientific article

Gp78 E3 Ubiquitin Ligase: Essential Functions and Contributions in Proteostasis

scientific article published on 25 August 2017

Heavy Metal Contamination of Soil, Irrigation Water and Vegetables in Peri-Urban Agricultural Areas and Markets of Delhi

scientific article published on January 2015

Identification and characterization of two conserved G-quadruplex forming motifs in the Nipah virus genome and their interaction with G-quadruplex specific ligands

scientific article published on 30 January 2020

Intramolecular relaxation of flexible dendrimers with excluded volume

scientific article published on 01 July 2014

Lanosterol Suppresses the Aggregation and Cytotoxicity of Misfolded Proteins Linked with Neurodegenerative Diseases.

scientific article published on 19 January 2017

Lomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects

scientific article

Magnetic nanoparticle-mediated hyperthermia therapy induces tumour growth inhibition by apoptosis and Hsp90/AKT modulation.

scientific article published on 29 September 2015

Modulation of anti-endotoxin property of Temporin L by minor amino acid substitution in identified phenylalanine zipper sequence

scientific article published on 8 September 2016

Molecular Understanding of Growth Inhibitory Effect from Irradiated to Bystander Tumor Cells in Mouse Fibrosarcoma Tumor Model ⬇️

scientific article

Molecular structure (monomeric and dimeric) and hydrogen bonds in 5-benzyl 2-thiohydantoin studied by FT-IR and FT-Raman spectroscopy and DFT calculations

scientific article published on 30 April 2014

Myricetin Reduces Toxic Level of CAG Repeats RNA in Huntington's Disease (HD) and Spino Cerebellar Ataxia (SCAs).

scientific article published on 27 November 2017

NALDB: nucleic acid ligand database for small molecules targeting nucleic acid.

scientific article published on 20 February 2016

Nanoemulsion based concomitant delivery of curcumin and etoposide: impact on cross talk between prostate cancer cells and osteoblast during metastasis.

scientific article published on November 2014

Orientational relaxation in semiflexible dendrimers.

scientific article published in December 2013

Pharmacological activation of protein kinase A improves memory loss and neuropathological changes in a mouse model of dementia of Alzheimer's type

scientific article published on 7 February 2017

Piperine Modulates Protein Mediated Toxicity in Fragile X-Associated Tremor/Ataxia Syndrome through Interacting Expanded CGG Repeat (r(CGG)exp) RNA

scientific article published on 02 July 2019

Piscidin-1-analogs with double L- and D-lysine residues exhibited different conformations in lipopolysaccharide but comparable anti-endotoxin activities

scientific article published on 04 January 2017

Polyphenolic flavonoid (Myricetin) upregulated proteasomal degradation mechanisms: Eliminates neurodegenerative proteins aggregation

scientific article published on 19 April 2019

Post-Ugi gold-catalyzed diastereoselective domino cyclization for the synthesis of diversely substituted spiroindolines

scientific article

Proteolysis to Identify Protease Substrates: Cleave to Decipher

scientific article

Radioprotection by macerated extract of Nigella sativa in normal tissues of fibrosarcoma bearing mice ⬇️

scientific article published on September 1, 2012

Rational truncation of aptamer for cross-species application to detect krait envenomation

scientific article published in Scientific Reports

Rationally designed small molecules targeting toxic CAG repeat RNA that causes Huntington's disease (HD) and spinocerebellar ataxia (SCAs)

scientific article published on 08 May 2019

Roles for root iron plaque in sequestration and uptake of heavy metals and metalloids in aquatic and wetland plants

scientific article

SMMDB: a web-accessible database for small molecule modulators and their targets involved in neurological diseases

scientific article published on 01 January 2018

Scrutinizing the SARS-CoV-2 protein information for the designing an effective vaccine encompassing both the T-cell and B-cell epitopes

scientific article published on 01 April 2020

Selenate mitigates arsenite toxicity in rice (Oryza sativa L.) by reducing arsenic uptake and ameliorates amino acid content and thiol metabolism.

scientific article published on 3 August 2016

Selenium ameliorates arsenic induced oxidative stress through modulation of antioxidant enzymes and thiols in rice (Oryza sativa L.).

scientific article published on 2 July 2014

Silymarin ameliorates memory deficits and neuropathological changes in mouse model of high-fat-diet-induced experimental dementia

scientific article published on 28 May 2014

Single Amino Acid Substitutions at Specific Positions of the Heptad Repeat Sequence of Piscidin-1 Yielded Novel Analogs That Show Low Cytotoxicity and In Vitro and In Vivo Antiendotoxin Activity

scientific article published on 11 April 2016

Structural Insight into the interaction of Flavonoids with Human Telomeric Sequence

scientific article published on 2 December 2015

Structural Insights Reveal the Dynamics of the Repeating r(CAG) Transcript Found in Huntington's Disease (HD) and Spinocerebellar Ataxias (SCAs)

scientific article published on 6 July 2015

Structural insight for the recognition of G-quadruplex structure at human c-myc promoter sequence by flavonoid Quercetin

scientific article

Structural switching electrochemical DNA aptasensor for the rapid diagnosis of tuberculous meningitis

scientific article published on 26 March 2019

Switching the regioselectivity via indium(III) and gold(I) catalysis: a post-Ugi intramolecular hydroarylation to azepino- and azocino-[c,d]indolones.

scientific article published in August 2013

Synthesis of 2-alkoxy and 2-benzyloxy analogues of estradiol as anti-breast cancer agents through microtubule stabilization

scientific article published on 10 September 2014

Synthesis of combretastatin A4 analogues on steroidal framework and their anti-breast cancer activity ⬇️

scientific article published on February 28, 2013

Synthesis of neolignans as microtubule stabilisers.

scientific article published on 9 January 2014

Synthesis of oleic acid functionalized Fe3O4 magnetic nanoparticles and studying their interaction with tumor cells for potential hyperthermia applications ⬇️

scientific article published on March 14, 2013

Synthesis of β-C-Glycopyranosyl Aldehydes and 2,6-Anhydro-heptitols

scientific article published on 08 October 2015

Synthesis, characterization and augmented anticancer potential of PEG-betulinic acid conjugate.

scientific article

Synthesis, molecular structure, hydrogen-bonding, NBO and chemical reactivity analysis of a novel 1,9-bis(2-cyano-2-ethoxycarbonylvinyl)-5-(4-hydroxyphenyl)-dipyrromethane: A combined experimental and theoretical (DFT and QTAIM) approach ⬇️

scientific article published on May 15, 2013

Thorium induced cytoproliferative effect in human liver cell HepG2: role of insulin-like growth factor 1 receptor and downstream signaling.

scientific article published on 22 January 2014

Variants of self-assembling peptide, KLD-12 that show both rapid fracture healing and antimicrobial properties.

scientific article published on 16 April 2015

Withaferin A: a proteasomal inhibitor promotes healing after injury and exerts anabolic effect on osteoporotic bone ⬇️

scientific article published on August 22, 2013

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