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List of works by Edward A. Fon

A light-inducible protein clustering system for in vivo analysis of α-synuclein aggregation in Parkinson disease

scientific article published on 09 March 2022

A new pathway for mitochondrial quality control: mitochondrial-derived vesicles

scientific article

A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling

scientific article published on 23 July 2006

Analysis of common and rare VPS13C variants in late-onset Parkinson disease

scientific article published on 09 January 2020

Association study of essential tremor genetic loci in Parkinson's disease

scientific article published on 6 January 2018

Ataxin-3 Deubiquitination Is Coupled to Parkin Ubiquitination via E2 Ubiquitin-conjugating Enzyme ⬇️

scientific article published on November 11, 2011

Ataxin-3 and its e3 partners: implications for machado-joseph disease

scientific article published on 06 May 2013

BAG5 inhibits parkin and enhances dopaminergic neuron degeneration

scientific article

Clearance of intracellular tau protein from neuronal cells via VAMP8-induced secretion

scientific article published on 22 October 2020

Cyberinfrastructure for Open Science at the Montreal Neurological Institute

scientific article (publication date: 6 January 2017)

Defending the mitochondria: The pathways of mitophagy and mitochondrial-derived vesicles

scientific article

Disruption of GRIN2B Impairs Differentiation in Human Neurons

Endocytic membrane trafficking and neurodegenerative disease

scientific article published on 31 December 2015

EphA4 is localized in clathrin-coated and synaptic vesicles in adult mouse brain

scientific article published on 12 January 2010

EphA4 signaling regulates phospholipase Cgamma1 activation, cofilin membrane association, and dendritic spine morphology.

scientific article

Expanding horizons at Big Sky. Symposium on ubiquitin and signaling

scientific article published on 6 July 2007

Fine-Mapping of SNCA in Rapid Eye Movement Sleep Behavior Disorder and Overt Synucleinopathies

scientific article published on 12 February 2020

Full sequencing and haplotype analysis of MAPT in Parkinson's disease and rapid eye movement sleep behavior disorder

scholarly article by Jiao Li et al published July 2018 in Movement Disorders

Genetic, Structural, and Functional Evidence Link TMEM175 to Synucleinopathies

scientific article published on 18 November 2019

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Investigation of C9orf72 repeat expansions in Parkinson's disease ⬇️

scientific article published on December 27, 2012

Isolation of human proteasomes and putative proteasome-interacting proteins using a novel affinity chromatography method

scientific article

LRRK2 localizes to endosomes and interacts with clathrin-light chains to limit Rac1 activation

scientific article

Long-term potentiation in isolated dendritic spines

scientific article

MFN2 retrotranslocation boosts mitophagy by uncoupling mitochondria from the ER

scholarly article by Gian-Luca McLelland published in January 2018

Methamphetamine-induced degeneration of dopaminergic neurons involves autophagy and upregulation of dopamine synthesis.

scientific article

Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy.

scientific article

Midbrain organoids with an <i>SNCA</i> gene triplication model key features of synucleinopathy

scientific article published on 25 September 2021

Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment ⬇️

scientific article published on April 1, 2012

Mitochondrial quality control in health and in Parkinson’s disease

scientific article published in 2022

Mutant ataxin-3 promotes the autophagic degradation of parkin ⬇️

scientific article published on 01 February 2011

Normal biogenesis and cycling of empty synaptic vesicles in dopamine neurons of vesicular monoamine transporter 2 knockout mice

scientific article published on 20 October 2004

One Step Into the Future: New iPSC Tools to Advance Research in Parkinson’s Disease and Neurological Disorders

scientific article published on 23 May 2019

Parkin and CASK/LIN-2 associate via a PDZ-mediated interaction and are co-localized in lipid rafts and postsynaptic densities in brain

scientific journal article

Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control

scientific journal article

Parkin- and PINK1-Dependent Mitophagy in Neurons: Will the Real Pathway Please Stand Up?

scientific article published on 19 July 2013

Parkin-mediated monoubiquitination of the PDZ protein PICK1 regulates the activity of acid-sensing ion channels

scientific article

Pre-synaptic and post-synaptic localization of EphA4 and EphB2 in adult mouse forebrain

scientific article

Presenting mitochondrial antigens: PINK1, Parkin and MDVs steal the show

scientific article published on 2 September 2016

Proteomic Profiling of Mitochondrial-Derived Vesicles in Brain Reveals Enrichment of Respiratory Complex Sub-assemblies and Small TIM Chaperones

scientific article published on 26 November 2020

SH3 domains from a subset of BAR proteins define a Ubl-binding domain and implicate parkin in synaptic ubiquitination

scientific article

Selective localization of Mfn2 near PINK1 enables its preferential ubiquitination by Parkin on mitochondria

scientific article published on 19 January 2022

Sequencing of the GBA coactivator, Saposin C, in Parkinson disease

scholarly article by Bouchra Ouled Amar Bencheikh et al published 2 July 2018 in Neurobiology of Aging

Short mitochondrial ARF triggers Parkin/PINK1-dependent mitophagy

scientific article

Structure and Function of Parkin, PINK1, and DJ-1, the Three Musketeers of Neuroprotection

scientific article

Structure of parkin reveals mechanisms for ubiquitin ligase activation

scientific article

Structure-guided mutagenesis reveals a hierarchical mechanism of Parkin activation

scientific article

Syntaxin-17 delivers PINK1/parkin-dependent mitochondrial vesicles to the endolysosomal system.

scientific article published on 25 July 2016

TOX3 Variants Are Involved in Restless Legs Syndrome and Parkinson's Disease with Opposite Effects

scientific article

The E3 ubiquitin ligase parkin is recruited to the 26 S proteasome via the proteasomal ubiquitin receptor Rpn13

scientific article

The Machado-Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability

scientific article

The Neuroprotective Role of Protein Quality Control in Halting the Development of Alpha-Synuclein Pathology

scientific article published on 27 September 2017

The TOMM machinery is a molecular switch in PINK1 and PARK2/PARKIN-dependent mitochondrial clearance

scientific article

The three 'P's of mitophagy: PARKIN, PINK1, and post-translational modifications

scientific article

USP8 and PARK2/parkin-mediated mitophagy

scientific article published on January 2015

USP8 regulates mitophagy by removing K6-linked ubiquitin conjugates from parkin

scientific article

USP9x-mediated deubiquitination of EFA6 regulates de novo tight junction assembly

scientific article

Ubiquilin recruits Eps15 into ubiquitin-rich cytoplasmic aggregates via a UIM-UBL interaction

scientific article

Ubiquitin is phosphorylated by PINK1 to activate parkin

scientific article

Variants in the Niemann-Pick type C gene NPC1 are not associated with Parkinson's disease

scientific article published on 08 April 2020

Wengen, the sole tumour necrosis factor receptor in Drosophila, collaborates with moesin to control photoreceptor axon targeting during development

scientific article published on 27 March 2013

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