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List of works by Knut Erik Tollefsen

17α-Ethinylestradiol (EE2) effect on global gene expression in primary rainbow trout (Oncorhynchus mykiss) hepatocytes

scientific article published on 28 October 2015

6TH NORWEGIAN ENVIRONMENTAL TOXICOLOGY SYMPOSIUM: Assessing and solving environmental challenges in a multiple stressor world

scientific article published on 22 August 2017

A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment

scientific article

Accumulation and disposition of hexabromocyclododecane (HBCD) in juvenile rainbow trout (Oncorhynchus mykiss).

scientific article published on 4 September 2009

Applying Adverse Outcome Pathways (AOPs) to support Integrated Approaches to Testing and Assessment (IATA).

scientific article published on 27 September 2014

Assessing combined toxicity of estrogen receptor agonists in a primary culture of rainbow trout (Oncorhynchus mykiss) hepatocytes ⬇️

scientific article published on October 25, 2010

Assessment of a novel device for onsite integrative large-volume solid phase extraction of water samples to enable a comprehensive chemical and effect-based analysis

scientific article published on 3 January 2017

Assessment of toxicological profiles of the municipal wastewater effluents using chemical analyses and bioassays

scientific article published on 15 December 2010

Automated high-throughput in vitro screening of the acetylcholine esterase inhibiting potential of environmental samples, mixtures and single compounds

scientific article published on 13 April 2016

Balsa raft crossing the Pacific finds low contaminant levels

scientific article published in July 2009

Bioconcentration of the intense sweetener sucralose in a multitrophic battery of aquatic organisms

Characterization of AhR agonist compounds in roadside snow

scientific article published on 27 April 2012

Characterizing combined effects of antiestrogenic chemicals on vitellogenin production in rainbow trout (Oncorhynchus mykiss) hepatocytes

scientific article published on 29 August 2017

Characterizing cytotoxic and estrogenic activity of Arctic char tissue extracts in primary Arctic char hepatocytes

scientific article published in September 2017

Combined effects of oestrogen receptor antagonists on in vitro vitellogenesis ⬇️

scientific article published on February 6, 2012

Deciphering the Combined Effects of Environmental Stressors on Gene Transcription: A Conceptual Approach

scientific article published on 11 April 2018

Development of a list of reference chemicals for evaluating alternative methods to in vivo fish bioaccumulation tests.

scientific article published on 6 November 2014

Development of a screening system for the detection of chemically induced DNA methylation alterations in a zebrafish liver cell line

scientific article published on January 2014

Diofenolan induces male offspring production through binding to the juvenile hormone receptor in Daphnia magna

scientific article published on 24 November 2014

Dose-dependent hepatic transcriptional responses in Atlantic salmon (Salmo salar) exposed to sublethal doses of gamma radiation

scientific article published on 04 August 2014

Early stress responses in Atlantic salmon (Salmo salar) exposed to environmentally relevant concentrations of uranium

scientific article published on 3 February 2012

Ecdysone Receptor Agonism Leading to Lethal Molting Disruption in Arthropods: Review and Adverse Outcome Pathway Development

scientific article published on 29 March 2017

Ecdysteroid and juvenile hormone biosynthesis, receptors and their signaling in the freshwater microcrustacean Daphnia

scientific article published on 13 December 2017

Effects of chronic dietary petroleum exposure on reproductive development in polar cod (Boreogadus saida).

scientific article published on 4 October 2016

Effects of silver and gold nanoparticles on rainbow trout (Oncorhynchus mykiss) hepatocytes

scientific article published in October 2009

Environmental risk assessment of combined effects in aquatic ecotoxicology: a discussion paper

scientific article

European demonstration program on the effect-based and chemical identification and monitoring of organic pollutants in European surface waters

scientific article published on 14 June 2017

Evaluation of the sensitivity, responsiveness and reproducibility of primary rainbow trout hepatocyte vitellogenin expression as a screening assay for estrogen mimics

scientific article published on 18 December 2014

Exposure of brown trout (Salmo trutta L.) to tunnel wash water runoff--chemical characterisation and biological impact

scientific article published on 9 April 2010

Framework for the quantitative weight-of-evidence analysis of 'omics data for regulatory purposes

scientific article published on 13 October 2017

Future water quality monitoring--adapting tools to deal with mixtures of pollutants in water resource management

scientific article published on 31 January 2015

Gamma radiation induces dose-dependent oxidative stress and transcriptional alterations in the freshwater crustacean Daphnia magna

scientific article published on 9 February 2018

Global transcriptional analysis of short-term hepatic stress responses in Atlantic salmon (Salmo salar) exposed to depleted uranium

scientific article published on 7 October 2014

Hepatic transcriptional responses in Atlantic salmon (Salmo salar) exposed to gamma radiation and depleted uranium singly and in combination

scientific article published on 18 April 2016

Hepatic transcriptomic profiling reveals early toxicological mechanisms of uranium in Atlantic salmon (Salmo salar)

scientific article

Identification of petrogenic produced water components as acetylcholine esterase inhibitors

scientific article published on 11 May 2016

Individual and molecular level effects of produced water contaminants on nauplii and adult females of Calanus finmarchicus

scientific article published in January 2016

Linking mode of action of the model respiratory and photosynthesis uncoupler 3,5-dichlorophenol to adverse outcomes in Lemna minor

scientific article published on 10 February 2018

Mixture toxicity of five biocides with dissimilar modes of action on the growth and photosystem II efficiency of Chlamydomonas reinhardtii

scientific article published on 29 August 2017

Monitoring North Sea oil production discharges using passive sampling devices coupled with in vitro bioassay techniques ⬇️

scientific article published on August 4, 2010

Monitoring the freely dissolved concentrations of polycyclic aromatic hydrocarbons (PAH) and alkylphenols (AP) around a Norwegian oil platform by holistic passive sampling

scientific article published on 13 August 2009

Mortality and transcriptional effects of inorganic mercury in the marine copepod Calanus finmarchicus

scientific article published on 25 August 2017

Occurrence and removal of selected organic micropollutants at mechanical, chemical and advanced wastewater treatment plants in Norway

scientific article

Oxidative stress in the algae Chlamydomonas reinhardtii exposed to biocides

scientific article published on 31 May 2017

Practical approaches to adverse outcome pathway development and weight-of-evidence evaluation as illustrated by ecotoxicological case studies

scientific article published on 15 February 2017

Presence, fate and effects of the intense sweetener sucralose in the aquatic environment ⬇️

scientific article published on September 30, 2012

Primary hepatocytes from Arctic char (Salvelinus alpinus) as a relevant Arctic in vitro model for screening contaminants and environmental extracts

scientific article

Repeatability and Reproducibility of the RTgill-W1 Cell Line Assay for Predicting Fish Acute Toxicity.

scientific article

Sensitivity of the green algae Chlamydomonas reinhardtii to gamma radiation: Photosynthetic performance and ROS formation

scientific article

The Challenge: Adverse outcome pathways in research and regulation--Current status and future perspectives

scientific article

The Role of Omics in the Application of Adverse Outcome Pathways for Chemical Risk Assessment

scientific article

The SOLUTIONS project: challenges and responses for present and future emerging pollutants in land and water resources management

scientific article

Toxicity of organic compounds from unresolved complex mixtures (UCMs) to primary fish hepatocytes

scientific article published on 29 June 2017

Transcriptional changes in Atlantic salmon (Salmo salar) after embryonic exposure to road salt

scientific article published on 22 October 2015

Transcriptomic analysis reveals dose-dependent modes of action of benzo(a)pyrene in polar cod (Boreogadus saida)

article published in 2018

Transcriptomic analysis reveals dose-dependent modes of action of benzo(a)pyrene in polar cod (Boreogadus saida)

Transgenic (cyp19a1b-GFP) zebrafish embryos as a tool for assessing combined effects of oestrogenic chemicals

scientific article published on 9 May 2013

Uptake and effects of manufactured silver nanoparticles in rainbow trout (Oncorhynchus mykiss) gill cells

scientific article published on 25 September 2010

Uptake of some selected aquatic pollutants in semipermeable membrane devices (SPMDs) and the polar organic chemical integrative sampler (POCIS).

scientific article

Whole-Organism Transcriptomic Analysis Provides Mechanistic Insight into the Acute Toxicity of Emamectin Benzoate in Daphnia magna

scientific article published on 5 October 2016

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