List of works - Håkan Wallin

A Multilaboratory Toxicological Assessment of a Panel of 10 Engineered Nanomaterials to Human Health--ENPRA Project--The Highlights, Limitations, and Current and Future Challenges

scientific article published on January 2016

A haplotype of polymorphisms in ASE-1, RAI and ERCC1 and the effects of tobacco smoking and alcohol consumption on risk of colorectal cancer: a Danish prospective case-cohort study

scientific article

A specific haplotype of single nucleotide polymorphisms on chromosome 19q13.2-3 encompassing the gene RAI is indicative of post-menopausal breast cancer before age 55.

scientific article published on May 2003

A sucrose-rich diet induces mutations in the rat colon.

scientific article published in August 2002

Acute and subacute pulmonary toxicity and mortality in mice after intratracheal instillation of ZnO nanoparticles in three laboratories

scientific article published on 7 August 2015

Airway irritation, inflammation, and toxicity in mice following inhalation of metal oxide nanoparticles

scientific article published on 21 June 2016

An experimental protocol for maternal pulmonary exposure in developmental toxicology

scientific article

Associations between COX-2 polymorphisms, blood cholesterol and risk of acute coronary syndrome

scientific article published on 28 August 2009

Associations between GPX1 Pro198Leu polymorphism, erythrocyte GPX activity, alcohol consumption and breast cancer risk in a prospective cohort study

scientific article published on 14 November 2005

Biodistribution of Carbon Nanotubes in Animal Models

scientific article published on 16 November 2016

Biodistribution of gold nanoparticles in mouse lung following intratracheal instillation

scientific article

COX-2 and p53 in human sinonasal cancer: COX-2 expression is associated with adenocarcinoma histology and wood-dust exposure

scientific article published on May 2008

Carbon black nanoparticle instillation induces sustained inflammation and genotoxicity in mouse lung and liver ⬇️

scientific article published on February 2, 2012

Carbon black nanoparticle intratracheal instillation does not alter cardiac gene expression

scientific article published in December 2013

Carbon black nanoparticles induce biphasic gene expression changes associated with inflammatory responses in the lungs of C57BL/6 mice following a single intratracheal instillation

scientific article published on 6 November 2015

Changes in cholesterol homeostasis and acute phase response link pulmonary exposure to multi-walled carbon nanotubes to risk of cardiovascular disease

scientific article published on 22 January 2015

Characterization of genotoxic response to 15 multiwalled carbon nanotubes with variable physicochemical properties including surface functionalizations in the FE1-Muta(TM) mouse lung epithelial cell line

scientific article

Chromatin structure studied by linear dichroism at different salt concentrations

scientific article published in 1982

Combinations of polymorphisms in XPD, XPC and XPA in relation to risk of lung cancer

scientific article

Comparative hazard identification by a single dose lung exposure of zinc oxide and silver nanomaterials in mice

scientific article

Comparison of dust release from epoxy and paint nanocomposites and conventional products during sanding and sawing.

scientific article published on 16 July 2014

Correction: Effects of prenatal exposure to surface-coated nanosized titanium dioxide (UV-Titan). A study in mice.

scientific article published on 5 May 2011

Cytokine expression in mice exposed to diesel exhaust particles by inhalation. Role of tumor necrosis factor

scientific article

DNA adduct formation and oxidative stress in colon and liver of Big Blue rats after dietary exposure to diesel particles

scientific article

DNA damage in lung after oral exposure to diesel exhaust particles in Big Blue rats

scientific article published in June 2004

DNA strand breaks, acute phase response and inflammation following pulmonary exposure by instillation to the diesel exhaust particle NIST1650b in mice.

scientific article published on 14 March 2015

Diesel exhaust particles are mutagenic in FE1-MutaMouse lung epithelial cells

scientific article

Diesel exhaust particles: effects on neurofunction in female mice

scientific article published on 27 March 2009

Dietary elevated sucrose modulation of diesel-induced genotoxicity in the colon and liver of Big Blue rats

scientific article

Dietary exposure to diesel exhaust particles and oxidatively damaged DNA in young oxoguanine DNA glycosylase 1 deficient mice

scientific article published on 21 September 2007

Dietary low-dose sucrose modulation of IQ-induced genotoxicity in the colon and liver of Big Blue rats

scientific article published in June 2003

Does intranasal instillation TiO2 cause pulmonary tumorigenesis in male mice?

scientific article published on 21 October 2017

Effect of increased intake of dietary animal fat and fat energy on oxidative damage, mutation frequency, DNA adduct level and DNA repair in rat colon and liver

scientific journal article

Effects of polymorphisms in ERCC1, ASE-1 and RAI on the risk of colorectal carcinomas and adenomas: a case control study

scientific article

Effects of prenatal exposure to diesel exhaust particles on postnatal development, behavior, genotoxicity and inflammation in mice

scientific article published on 11 March 2008

Effects of prenatal exposure to surface-coated nanosized titanium dioxide (UV-Titan). A study in mice

scientific article

Engineered nanomaterial risk. Lessons learnt from completed nanotoxicology studies: potential solutions to current and future challenges

scientific article

Epoxy composite dusts with and without carbon nanotubes cause similar pulmonary responses, but differences in liver histology in mice following pulmonary deposition

scientific article

Exposure of pregnant mice to carbon black by intratracheal instillation: toxicogenomic effects in dams and offspring

scientific article published on 6 October 2011

FIB-SEM imaging of carbon nanotubes in mouse lung tissue

scientific article

Gene-environment interactions between smoking and a haplotype of RAI, ASE-1 and ERCC1 polymorphisms among women in relation to risk of lung cancer in a population-based study

article

Genotoxicity, cytotoxicity, and reactive oxygen species induced by single-walled carbon nanotubes and C(60) fullerenes in the FE1-Mutatrade markMouse lung epithelial cells

scientific article

Genotoxicity, inflammation and physico-chemical properties of fine particle samples from an incineration energy plant and urban air.

scientific article

Hepatic and pulmonary toxicogenomic profiles in mice intratracheally instilled with carbon black nanoparticles reveal pulmonary inflammation, acute phase response, and alterations in lipid homeostasis

scientific article

Identification of Gene Transcription Start Sites and Enhancers Responding to Pulmonary Carbon Nanotube Exposure in Vivo

scientific article published on 27 March 2017

In utero exposure to nanosized carbon black (Printex90) does not induce tandem repeat mutations in female murine germ cells

scientific article

In vitro assessment of engineered nanomaterials using a hepatocyte cell line: cytotoxicity, pro-inflammatory cytokines and functional markers

scientific article published on 20 January 2012

Increased mRNA expression levels of ERCC1, OGG1 and RAI in colorectal adenomas and carcinomas

scientific article

Increased mutant frequency by carbon black, but not quartz, in the lacZ and cII transgenes of muta mouse lung epithelial cells

scientific article

Inflammation and Vascular Effects after Repeated Intratracheal Instillations of Carbon Black and Lipopolysaccharide

scientific article

Inflammation but no DNA (deoxyribonucleic acid) damage in mice exposed to airborne dust from a biofuel plant

scientific article published in August 2008

Inflammatory and genotoxic effects of diesel particles in vitro and in vivo

scientific article published on August 2004

Inflammatory and genotoxic effects of sanding dust generated from nanoparticle-containing paints and lacquers

scientific article published on 13 October 2011

Inflammatory response and genotoxicity of seven wood dusts in the human epithelial cell line A549.

scientific article

Inhalation of ozone induces DNA strand breaks and inflammation in mice

scientific article published in September 2002

Interaction between ADH1C Arg(272)Gln and alcohol intake in relation to breast cancer risk suggests that ethanol is the causal factor in alcohol related breast cancer

scientific article published on 28 March 2010

K-ras mutations in sinonasal cancers in relation to wood dust exposure

scientific article

Kupffer cells are central in the removal of nanoparticles from the organism

scientific article

MWCNTs of different physicochemical properties cause similar inflammatory responses, but differences in transcriptional and histological markers of fibrosis in mouse lungs

scientific article published on 29 December 2014

Maternal inhalation of surface-coated nanosized titanium dioxide (UV-Titan) in C57BL/6 mice: effects in prenatally exposed offspring on hepatic DNA damage and gene expression

scientific article published on 28 November 2011

Meta-analysis of transcriptomic responses as a means to identify pulmonary disease outcomes for engineered nanomaterials

scientific article

Multi-walled carbon nanotube-induced genotoxic, inflammatory and pro-fibrotic responses in mice: Investigating the mechanisms of pulmonary carcinogenesis

scientific article

Multi-walled carbon nanotube-physicochemical properties predict the systemic acute phase response following pulmonary exposure in mice

scientific article

Mutagenicity of 2-amino-3-methylimidazo[4,5-f]quinoline in colon and liver of Big Blue rats: role of DNA adducts, strand breaks, DNA repair and oxidative stress

scientific article published in August 2002

Mutation spectrum in FE1-MUTA(TM) Mouse lung epithelial cells exposed to nanoparticulate carbon black

scientific article published on 20 October 2010

Mutations in TP53 tumor suppressor gene in wood dust-related sinonasal cancer

article

Nano-risk Science: application of toxicogenomics in an adverse outcome pathway framework for risk assessment of multi-walled carbon nanotubes

scientific article

Nanomaterial translocation--the biokinetics, tissue accumulation, toxicity and fate of materials in secondary organs--a review

scientific article published on 03 July 2015

Nanotitanium dioxide toxicity in mouse lung is reduced in sanding dust from paint

scientific article published on 2 February 2012

No association between OGG1 Ser326Cys and risk of basal cell carcinoma.

scientific article

No association between the DNA repair gene XRCC3 T241M polymorphism and risk of skin cancer and breast cancer.

scientific article

Oxidative DNA damage and defence gene expression in the mouse lung after short-term exposure to diesel exhaust particles by inhalation

scientific article published on 14 August 2003

Oxidative DNA damage in vitamin C-supplemented guinea pigs after intratracheal instillation of diesel exhaust particles

scientific article published in May 2003

Oxidative stress, DNA damage, and inflammation induced by ambient air and wood smoke particulate matter in human A549 and THP-1 cell lines

scientific article published on 14 January 2011

Oxidative stress, inflammation, and DNA damage in rats after intratracheal instillation or oral exposure to ambient air and wood smoke particulate matter

scientific article published on 23 September 2010

PPARgamma Pro12Ala polymorphism and risk of acute coronary syndrome in a prospective study of Danes

scientific article

Peroxisome proliferator-activated [corrected] receptor-gamma2 [corrected] Pro12Ala, interaction with alcohol intake and NSAID use, in relation to risk of breast cancer in a prospective study of Danes

scientific article published on 6 September 2006

Personal exposure to PM2.5 and biomarkers of DNA damage

scientific article published in March 2003

Polymorphisms in COX-2, NSAID use and risk of basal cell carcinoma in a prospective study of Danes

scientific article

Polymorphisms of the XRCC1, XRCC3 and XPD genes and risk of colorectal adenoma and carcinoma, in a Norwegian cohort: a case control study

scientific article published on 16 March 2006

Prenatal exposure to carbon black (printex 90): effects on sexual development and neurofunction

scientific article published on 20 July 2011

Prenatal exposure to diesel exhaust particles and effect on the male reproductive system in mice.

scientific article published on 24 July 2009

Profile of TP53 gene mutations in sinonasal cancer☆

article

Promise and peril in nanomedicine: the challenges and needs for integrated systems biology approaches to define health risk

scientific article published on 15 March 2017

Prospective study of interaction between alcohol, NSAID use and polymorphisms in genes involved in the inflammatory response in relation to risk of colorectal cancer

article

Pulmonary exposure to carbon black by inhalation or instillation in pregnant mice: effects on liver DNA strand breaks in dams and offspring

scientific article

Pulmonary instillation of low doses of titanium dioxide nanoparticles in mice leads to particle retention and gene expression changes in the absence of inflammation

scientific article published on April 2013

Repeated inhalations of diesel exhaust particles and oxidatively damaged DNA in young oxoguanine DNA glycosylase (OGG1) deficient mice

scientific article

Role of oxidative damage in toxicity of particulates

scientific article published on January 2010

Stat-6 signaling pathway and not Interleukin-1 mediates multi-walled carbon nanotube-induced lung fibrosis in mice: insights from an adverse outcome pathway framework

scientific article published on 13 September 2017

Sucrose and IQ induced mutations in rat colon by independent mechanism

scientific article published in October 2004

Sunlight-induced DNA damage in human mononuclear cells

scientific article

Surface modification does not influence the genotoxic and inflammatory effects of TiO2 nanoparticles after pulmonary exposure by instillation in mice

scientific article

The NFKB1 ATTG ins/del polymorphism and risk of coronary heart disease in three independent populations

scientific article published on 17 June 2011

Time-dependent subcellular distribution and effects of carbon nanotubes in lungs of mice

scientific article

Tissue distribution and elimination after oral and intravenous administration of different titanium dioxide nanoparticles in rats

scientific article

Transcriptional profiling identifies physicochemical properties of nanomaterials that are determinants of the in vivo pulmonary response

scientific article published on 11 December 2014

Tumor necrosis factor is not required for particle-induced genotoxicity and pulmonary inflammation

Two regions in chromosome 19q13.2-3 are associated with risk of lung cancer

scientific article published on February 2004

Urinary 1-hydroxypyrene and mutagenicity in bus drivers and mail carriers exposed to urban air pollution in Denmark

scientific article published on January 2004

XPA A23G, XPC Lys939Gln, XPD Lys751Gln and XPD Asp312Asn polymorphisms, interactions with smoking, alcohol and dietary factors, and risk of colorectal cancer

scientific article

List of works by Håkan Wallin

A Multilaboratory Toxicological Assessment of a Panel of 10 Engineered Nanomaterials to Human Health--ENPRA Project--The Highlights, Limitations, and Current and Future Challenges

A haplotype of polymorphisms in ASE-1, RAI and ERCC1 and the effects of tobacco smoking and alcohol consumption on risk of colorectal cancer: a Danish prospective case-cohort study

A specific haplotype of single nucleotide polymorphisms on chromosome 19q13.2-3 encompassing the gene RAI is indicative of post-menopausal breast cancer before age 55.

A sucrose-rich diet induces mutations in the rat colon.

Acute and subacute pulmonary toxicity and mortality in mice after intratracheal instillation of ZnO nanoparticles in three laboratories

Airway irritation, inflammation, and toxicity in mice following inhalation of metal oxide nanoparticles

An experimental protocol for maternal pulmonary exposure in developmental toxicology

Associations between COX-2 polymorphisms, blood cholesterol and risk of acute coronary syndrome

Associations between GPX1 Pro198Leu polymorphism, erythrocyte GPX activity, alcohol consumption and breast cancer risk in a prospective cohort study

Biodistribution of Carbon Nanotubes in Animal Models

Biodistribution of gold nanoparticles in mouse lung following intratracheal instillation

COX-2 and p53 in human sinonasal cancer: COX-2 expression is associated with adenocarcinoma histology and wood-dust exposure

Carbon black nanoparticle instillation induces sustained inflammation and genotoxicity in mouse lung and liver ⬇️

Carbon black nanoparticle intratracheal instillation does not alter cardiac gene expression

Carbon black nanoparticles induce biphasic gene expression changes associated with inflammatory responses in the lungs of C57BL/6 mice following a single intratracheal instillation

Changes in cholesterol homeostasis and acute phase response link pulmonary exposure to multi-walled carbon nanotubes to risk of cardiovascular disease

Characterization of genotoxic response to 15 multiwalled carbon nanotubes with variable physicochemical properties including surface functionalizations in the FE1-Muta(TM) mouse lung epithelial cell line

Chromatin structure studied by linear dichroism at different salt concentrations

Combinations of polymorphisms in XPD, XPC and XPA in relation to risk of lung cancer

Comparative hazard identification by a single dose lung exposure of zinc oxide and silver nanomaterials in mice

Comparison of dust release from epoxy and paint nanocomposites and conventional products during sanding and sawing.

Correction: Effects of prenatal exposure to surface-coated nanosized titanium dioxide (UV-Titan). A study in mice.

Cytokine expression in mice exposed to diesel exhaust particles by inhalation. Role of tumor necrosis factor

DNA adduct formation and oxidative stress in colon and liver of Big Blue rats after dietary exposure to diesel particles

DNA damage in lung after oral exposure to diesel exhaust particles in Big Blue rats

DNA strand breaks, acute phase response and inflammation following pulmonary exposure by instillation to the diesel exhaust particle NIST1650b in mice.

Diesel exhaust particles are mutagenic in FE1-MutaMouse lung epithelial cells

Diesel exhaust particles: effects on neurofunction in female mice

Dietary elevated sucrose modulation of diesel-induced genotoxicity in the colon and liver of Big Blue rats

Dietary exposure to diesel exhaust particles and oxidatively damaged DNA in young oxoguanine DNA glycosylase 1 deficient mice

Dietary low-dose sucrose modulation of IQ-induced genotoxicity in the colon and liver of Big Blue rats

Does intranasal instillation TiO2 cause pulmonary tumorigenesis in male mice?

Effect of increased intake of dietary animal fat and fat energy on oxidative damage, mutation frequency, DNA adduct level and DNA repair in rat colon and liver

Effects of polymorphisms in ERCC1, ASE-1 and RAI on the risk of colorectal carcinomas and adenomas: a case control study

Effects of prenatal exposure to diesel exhaust particles on postnatal development, behavior, genotoxicity and inflammation in mice

Effects of prenatal exposure to surface-coated nanosized titanium dioxide (UV-Titan). A study in mice

Engineered nanomaterial risk. Lessons learnt from completed nanotoxicology studies: potential solutions to current and future challenges

Epoxy composite dusts with and without carbon nanotubes cause similar pulmonary responses, but differences in liver histology in mice following pulmonary deposition

Exposure of pregnant mice to carbon black by intratracheal instillation: toxicogenomic effects in dams and offspring

FIB-SEM imaging of carbon nanotubes in mouse lung tissue

Gene-environment interactions between smoking and a haplotype of RAI, ASE-1 and ERCC1 polymorphisms among women in relation to risk of lung cancer in a population-based study

Genotoxicity, cytotoxicity, and reactive oxygen species induced by single-walled carbon nanotubes and C(60) fullerenes in the FE1-Mutatrade markMouse lung epithelial cells

Genotoxicity, inflammation and physico-chemical properties of fine particle samples from an incineration energy plant and urban air.

Hepatic and pulmonary toxicogenomic profiles in mice intratracheally instilled with carbon black nanoparticles reveal pulmonary inflammation, acute phase response, and alterations in lipid homeostasis

Identification of Gene Transcription Start Sites and Enhancers Responding to Pulmonary Carbon Nanotube Exposure in Vivo

In utero exposure to nanosized carbon black (Printex90) does not induce tandem repeat mutations in female murine germ cells

In vitro assessment of engineered nanomaterials using a hepatocyte cell line: cytotoxicity, pro-inflammatory cytokines and functional markers

Increased mRNA expression levels of ERCC1, OGG1 and RAI in colorectal adenomas and carcinomas

Increased mutant frequency by carbon black, but not quartz, in the lacZ and cII transgenes of muta mouse lung epithelial cells

Inflammation and Vascular Effects after Repeated Intratracheal Instillations of Carbon Black and Lipopolysaccharide

Inflammation but no DNA (deoxyribonucleic acid) damage in mice exposed to airborne dust from a biofuel plant

Inflammatory and genotoxic effects of diesel particles in vitro and in vivo

Inflammatory and genotoxic effects of sanding dust generated from nanoparticle-containing paints and lacquers

Inflammatory response and genotoxicity of seven wood dusts in the human epithelial cell line A549.

Inhalation of ozone induces DNA strand breaks and inflammation in mice

Interaction between ADH1C Arg(272)Gln and alcohol intake in relation to breast cancer risk suggests that ethanol is the causal factor in alcohol related breast cancer

K-ras mutations in sinonasal cancers in relation to wood dust exposure

Kupffer cells are central in the removal of nanoparticles from the organism

MWCNTs of different physicochemical properties cause similar inflammatory responses, but differences in transcriptional and histological markers of fibrosis in mouse lungs

Maternal inhalation of surface-coated nanosized titanium dioxide (UV-Titan) in C57BL/6 mice: effects in prenatally exposed offspring on hepatic DNA damage and gene expression

Meta-analysis of transcriptomic responses as a means to identify pulmonary disease outcomes for engineered nanomaterials

Multi-walled carbon nanotube-induced genotoxic, inflammatory and pro-fibrotic responses in mice: Investigating the mechanisms of pulmonary carcinogenesis

Multi-walled carbon nanotube-physicochemical properties predict the systemic acute phase response following pulmonary exposure in mice

Mutagenicity of 2-amino-3-methylimidazo[4,5-f]quinoline in colon and liver of Big Blue rats: role of DNA adducts, strand breaks, DNA repair and oxidative stress

Mutation spectrum in FE1-MUTA(TM) Mouse lung epithelial cells exposed to nanoparticulate carbon black

Mutations in TP53 tumor suppressor gene in wood dust-related sinonasal cancer

Nano-risk Science: application of toxicogenomics in an adverse outcome pathway framework for risk assessment of multi-walled carbon nanotubes

Nanomaterial translocation--the biokinetics, tissue accumulation, toxicity and fate of materials in secondary organs--a review

Nanotitanium dioxide toxicity in mouse lung is reduced in sanding dust from paint

No association between OGG1 Ser326Cys and risk of basal cell carcinoma.

No association between the DNA repair gene XRCC3 T241M polymorphism and risk of skin cancer and breast cancer.

Oxidative DNA damage and defence gene expression in the mouse lung after short-term exposure to diesel exhaust particles by inhalation

Oxidative DNA damage in vitamin C-supplemented guinea pigs after intratracheal instillation of diesel exhaust particles

Oxidative stress, DNA damage, and inflammation induced by ambient air and wood smoke particulate matter in human A549 and THP-1 cell lines

Oxidative stress, inflammation, and DNA damage in rats after intratracheal instillation or oral exposure to ambient air and wood smoke particulate matter

PPARgamma Pro12Ala polymorphism and risk of acute coronary syndrome in a prospective study of Danes

Peroxisome proliferator-activated [corrected] receptor-gamma2 [corrected] Pro12Ala, interaction with alcohol intake and NSAID use, in relation to risk of breast cancer in a prospective study of Danes

Personal exposure to PM2.5 and biomarkers of DNA damage

Polymorphisms in COX-2, NSAID use and risk of basal cell carcinoma in a prospective study of Danes