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List of works by Nicolle H R Litjens

A killer on the road: circulating CD4(+)CD28null T cells as cardiovascular risk factor in ESRD patients.

scientific article published on March 2012

Allogeneic Mature Human Dendritic Cells Generate Superior Alloreactive Regulatory T Cells in the Presence of IL-15.

scientific article

Belatacept Does Not Inhibit Follicular T Cell-Dependent B-Cell Differentiation in Kidney Transplantation.

scientific article published on 31 May 2017

CD4+ CD28null T cells are not alloreactive unless stimulated by interleukin-15.

scientific article published on 31 August 2017

CMV Primary Infection Is Associated With Donor-Specific T Cell Hyporesponsiveness and Fewer Late Acute Rejections After Liver Transplantation.

scientific article published on 5 May 2015

Chronic kidney disease and premature ageing of the adaptive immune response.

scientific article

Circulating CD4(+)CD28null T Cells May Increase the Risk of an Atherosclerotic Vascular Event Shortly after Kidney Transplantation.

scientific article published in October 2013

Circulating pro-inflammatory CD4posCD28null T cells are independently associated with cardiovascular disease in ESRD patients

scientific article published on 16 April 2010

Co-inhibitory profile and cytotoxicity of CD57+ PD-1- T cells in end-stage renal disease patients.

scientific article

Differential effects of age, cytomegalovirus-seropositivity and end-stage renal disease (ESRD) on circulating T lymphocyte subsets.

scientific article published on 8 January 2011

Effects of monomethylfumarate on dendritic cell differentiation.

scientific article

Encapsulating peritoneal sclerosis is associated with T-cell activation.

scientific article

End-Stage Renal Disease Causes Skewing in the TCR Vβ-Repertoire Primarily within CD8+ T Cell Subsets

scientific article published on 15 December 2017

Follicular T helper cells and humoral reactivity in kidney transplant patients

scientific article

IL-2 producing memory CD4+ T lymphocytes are closely associated with the generation of IgG-secreting plasma cells.

scientific article published in September 2008

Identification of circulating human antigen-reactive CD4+ FOXP3+ natural regulatory T cells.

scientific article

Impaired immune responses and antigen-specific memory CD4+ T cells in hemodialysis patients

scientific article published on 14 May 2008

In vitro pharmacokinetics of anti-psoriatic fumaric acid esters

scientific article

Latency for cytomegalovirus impacts T cell ageing significantly in elderly end-stage renal disease patients

scientific article published on 27 July 2016

Loss of CD28 on Peripheral T Cells Decreases the Risk for Early Acute Rejection after Kidney Transplantation

scientific article

Loss of renal function causes premature aging of the immune system.

scientific article published on 20 December 2013

Lymph node and circulating T cell characteristics are strongly correlated in end-stage renal disease patients, but highly differentiated T cells reside within the circulation.

scientific article published on 31 January 2017

Mesenchymal stem cells control alloreactive CD8(+) CD28(-) T cells

scientific article published in December 2013

Monomethylfumarate affects polarization of monocyte-derived dendritic cells resulting in down-regulated Th1 lymphocyte responses.

scientific article published in February 2004

Natural regulatory T cells from patients with end-stage renal disease can be used for large-scale generation of highly suppressive alloantigen-specific Tregs

scientific article published on 14 December 2016

Pharmacokinetics of oral fumarates in healthy subjects.

scientific article published in October 2004

Potential Beneficial Effects of Cytomegalovirus Infection after Transplantation.

scientific article published in March 2018

Premature aging of circulating T cells in patients with end-stage renal disease.

scientific article

Pretransplant Numbers of CD16+ Monocytes as a Novel Biomarker to Predict Acute Rejection After Kidney Transplantation: A Pilot Study.

scientific article published on 23 March 2017

Primary Cytomegalovirus Infection Significantly Impacts Circulating T Cells in Kidney Transplant Recipients.

scientific article published on 24 July 2015

Progressive loss of renal function is associated with activation and depletion of naive T lymphocytes.

scientific article published on 27 October 2005

Protective Cytomegalovirus (CMV)-Specific T-Cell Immunity Is Frequent in Kidney Transplant Patients without Serum Anti-CMV Antibodies

scientific article published on 12 September 2017

Rotterdam: main port for organ transplantation research in the Netherlands

scientific article published on 18 September 2014

Seropositivity for cytomegalovirus in patients with end-stage renal disease is strongly associated with atherosclerotic disease

scientific article published on 27 June 2007

Substantial proliferation of human renal tubular epithelial cell-reactive CD4+CD28null memory T cells, which is resistant to tacrolimus and everolimus

scientific article published in January 2014

Systemic varicella zoster virus reactive effector memory T-cells impaired in the elderly and in kidney transplant recipients.

scientific article published in December 2012

T-Cell Composition of the Lymph Node Is Associated with the Risk for Early Rejection after Renal Transplantation.

scientific article published on 27 October 2017

T-cell ageing in end-stage renal disease patients: Assessment and clinical relevance.

scientific article

Terminally differentiated CD8+ Temra cells are associated with the risk for acute kidney allograft rejection.

scientific article published in July 2012

The human alloreactive CD4+ T-cell repertoire is biased to a Th17 response and the frequency is inversely related to the number of HLA class II mismatches.

scientific article published on 27 August 2009

Time course of atrial fibrillation-induced cellular structural remodeling in atria of the goat

scientific article published on 01 December 2001

Uremia causes premature ageing of the T cell compartment in end-stage renal disease patients.

scientific article published on 12 September 2012

Uremia-Associated Premature Aging of T Cells Does Not Predict Infectious Complications After Renal Transplantation

scientific article

Uremia-associated immunological aging is stably imprinted in the T-cell system and not reversed by kidney transplantation.

scientific article published on 30 September 2014

pERK-dependent defective TCR-mediated activation of CD4+ T cells in end-stage renal disease patients.

scientific article published on 19 June 2017