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List of works by E. Sally Ward

3D RESOLUTION MEASURE FOR MULTIFOCAL PLANE MICROSCOPY.

scientific article

3D single molecule tracking and superresolution microscopy using multifocal plane microscopy

scientific article published on December 2012

3D single molecule tracking of quantum-dot labeled antibody molecules using multifocal plane microscopy

scientific article

3D single molecule tracking with multifocal plane microscopy reveals rapid intercellular transferrin transport at epithelial cell barriers

scientific article

A 3D Resolution Measure for Optical Microscopy

scientific article

A Distinct Class of Antibodies May Be an Indicator of Gray Matter Autoimmunity in Early and Established Relapsing Remitting Multiple Sclerosis Patients.

scientific article

A comparative study of high resolution microscopy imaging modalities using a three-dimensional resolution measure.

scientific article

A resolution measure for three-dimensional microscopy.

scientific article

A software framework for the analysis of complex microscopy image data.

scientific article

A state space based approach to localizing single molecules from multi-emitter images.

scientific article published in January 2017

A stochastic analysis of distance estimation approaches in single molecule microscopy - quantifying the resolution limits of photon-limited imaging systems.

scientific article published in September 2013

A two-stage method for automated detection of ring-like endosomes in fluorescent microscopy images

scientific article published on 27 June 2019

Achievable accuracy of parameter estimation for multidimensional NMR experiments.

scientific article published in July 2002

An information-theoretic approach to designing the plane spacing for multifocal plane microscopy.

scientific article published on February 2015

Analyses of TCR clustering at the T cell-antigen-presenting cell interface and its impact on the activation of naive CD4+ T cells

scientific article published on 27 September 2006

Analyses of the recycling receptor, FcRn, in live cells reveal novel pathways for lysosomal delivery.

scientific article

Analysis of autoreactive T cells associated with murine collagen-induced arthritis using peptide-MHC multimers.

scientific article

Analysis of exponential data using a noniterative technique: application to surface plasmon experiments.

scientific article

Antibody engineering: the use of Escherichia coli as an expression host ⬇️

scientific article published on April 1, 1992

Antibody targeting of HER2/HER3 signaling overcomes heregulin-induced resistance to PI3K inhibition in prostate cancer

scientific article

Antigen dynamics govern the induction of CD4(+) T cell tolerance during autoimmunity.

scientific article published on 25 May 2016

Antigen specificity of clonally expanded and receptor edited cerebrospinal fluid B cells from patients with relapsing remitting MS

scientific article published on 23 April 2007

Autoantibody depletion ameliorates disease in murine experimental autoimmune encephalomyelitis

scientific article published on 19 June 2013

Autoantigen immunization at different sites reveals a role for anti-inflammatory effects of IFN-gamma in regulating susceptibility to experimental autoimmune encephalomyelitis.

scientific article published on May 2009

BCAP links IL-1R to the PI3K-mTOR pathway and regulates pathogenic Th17 cell differentiation

scientific article published on 09 August 2018

Beyond Rayleigh's criterion: a resolution measure with application to single-molecule microscopy.

scientific article

Catabolism of the murine IgG1 molecule: evidence that both CH2-CH3 domain interfaces are required for persistence of IgG1 in the circulation of mice

scientific article published on 01 October 1994

Chapter 4: Multitasking by exploitation of intracellular transport functions the many faces of FcRn.

scientific article published on January 2009

Cloning and expression inEscherichia coliof the insecticidal δ-endotoxin gene ofBacillus thuringiensisvar.israelensis ⬇️

scientific article published on October 1, 1984

Commentary: "There's been a Flaw in Our Thinking".

scientific article published on 16 July 2015

Comparative stabilities in vitro and in vivo of a recombinant mouse antibody FvCys fragment and a bisFvCys conjugate ⬇️

scientific article published on July 1, 1992

Comparison of estimation algorithms in single-molecule localization.

scientific article published on February 2010

Compensation for loss of ligand activity in surface plasmon resonance experiments.

scientific article published in July 2002

Conditional deletion of the MHC class I-related receptor FcRn reveals the sites of IgG homeostasis in mice

scholarly article

Conferring the binding properties of the mouse MHC class I-related receptor, FcRn, onto the human ortholog by sequential rounds of site-directed mutagenesis

scientific article published on 16 December 2004

Crystal structure of a T cell receptor Valpha11 (AV11S5) domain: new canonical forms for the first and second complementarity determining regions

scientific article

Designing the focal plane spacing for multifocal plane microscopy

scientific article

Detection of autoreactive T cells in H-2u mice using peptide-MHC multimers

scientific article published on 01 November 2000

Determination of localization accuracy based on experimentally acquired image sets: applications to single molecule microscopy.

scientific article published on March 2015

Divergent activities of an engineered antibody in murine and human systems have implications for therapeutic antibodies

scholarly article

Dual objective fluorescence microscopy for single molecule imaging applications

scientific article

Elucidation of intracellular recycling pathways leading to exocytosis of the Fc receptor, FcRn, by using multifocal plane microscopy

scientific article

Engineered clearing agents for the selective depletion of antigen-specific antibodies

scientific article

Engineering a HER2-specific antibody-drug conjugate to increase lysosomal delivery and therapeutic efficacy

scientific article published on 01 April 2019

Engineering multivalent antibodies to target heregulin-induced HER3 signaling in breast cancer cells

scientific article published on 26 December 2013

Engineering the Fc region of immunoglobulin G to modulate in vivo antibody levels

scientific article published on 25 September 2005

Evidence that the hinge region plays a role in maintaining serum levels of the murine IgG1 molecule

scientific article published on 01 May 1995

Evidence to support the cellular mechanism involved in serum IgG homeostasis in humans

scientific article published on 01 February 2003

Exocytosis of IgG as mediated by the receptor, FcRn: an analysis at the single-molecule level

scientific article

Expression and Secretion of T-Cell Receptor Valpha and Vbeta Domains using Escherichia coli as a Host ⬇️

scientific article published on 01 August 1991

Expression of the tyrosine phosphatase SRC homology 2 domain-containing protein tyrosine phosphatase 1 determines T cell activation threshold and severity of experimental autoimmune encephalomyelitis.

scientific article published in May 2002

FISHER INFORMATION FOR EMCCD IMAGING WITH APPLICATION TO SINGLE MOLECULE MICROSCOPY

scientific article

FcRn: from molecular interactions to regulation of IgG pharmacokinetics and functions

scientific article published on January 2014

Feedback regulation of murine autoimmunity via dominant anti-inflammatory effects of interferon gamma.

scientific article

Fisher information matrix for branching processes with application to electron-multiplying charge-coupled devices

scientific article

Fisher information theory for parameter estimation in single molecule microscopy: tutorial

scientific article published on July 2016

Fluorescent Microspheres as Point Sources: A Localization Study.

scientific article published on 28 July 2015

From sorting endosomes to exocytosis: association of Rab4 and Rab11 GTPases with the Fc receptor, FcRn, during recycling.

scientific article

Functional expression of the MHC class I-related receptor, FcRn, in endothelial cells of mice.

scientific article

Generation of mutated variants of the human form of the MHC class I-related receptor, FcRn, with increased affinity for mouse immunoglobulin G.

scientific article published in September 2003

Hepatic function of FcRn revealed: Implications for overcoming drug-mediated hepatotoxicity.

scientific article

High accuracy 3D quantum dot tracking with multifocal plane microscopy for the study of fast intracellular dynamics in live cells

scientific article

How Accurately Can a Single Molecule be Localized when Imaged Through an Optical Microscope?

scientific article

How accurately can a single molecule be localized in three dimensions using a fluorescence microscope?

scientific article

Identification and function of neonatal Fc receptor in mammary gland of lactating mice.

scientific article

Improved single particle localization accuracy with dual objective multifocal plane microscopy.

scientific article

Increasing the affinity of a human IgG1 for the neonatal Fc receptor: biological consequences.

scientific article published in November 2002

Increasing the serum persistence of an IgG fragment by random mutagenesis.

scientific article published on July 1997

Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development

scientific article

Intensity-based axial localization approaches for multifocal plane microscopy.

scientific article

Investigating the usage of point spread functions in point source and microsphere localization.

scientific article published on February 2016

Investigation of the numerics of point spread function integration in single molecule localization

scientific article published in June 2015

Localization accuracy in single molecule microscopy using electron-multiplying charge-coupled device cameras.

scientific article published on March 2012

Localization accuracy in single-molecule microscopy

scientific article

Localizing single molecules in three dimensions - a brief review

scientific article

Loss of expression of the recycling receptor, FcRn, promotes tumor cell growth by increasing albumin consumption

scientific article published on 10 December 2016

Macrophage and NK-mediated killing of precursor-B acute lymphoblastic leukemia cells targeted with a-fucosylated anti-CD19 humanized antibodies

scientific article

Macrophage-Mediated Trogocytosis Leads to Death of Antibody-Opsonized Tumor Cells

scientific article published on 25 May 2016

Mapping the site on human IgG for binding of the MHC class I-related receptor, FcRn

scientific article published on 01 September 1999

Microscope calibration protocol for single-molecule microscopy

scientific article published on 01 January 2021

Molecular mimics can induce a nonautoaggressive repertoire that preempts induction of autoimmunity.

scientific article

Molecular requirements for T cell recognition by a major histocompatibility complex class II-restricted T cell receptor: the involvement of the fourth hypervariable loop of the Valpha domain.

scientific article

Myelin oligodendrocyte glycoprotein-specific antibodies from multiple sclerosis patients exacerbate disease in a humanized mouse model.

scientific article

Negative selection during the peripheral immune response to antigen

scientific article

Neonatal Fc receptor antagonist efgartigimod safely and sustainably reduces IgGs in humans

scientific article published on 24 July 2018

Neonatal Fc receptor blockade by Fc engineering ameliorates arthritis in a murine model

scientific article

Neonatal Fc receptor expression in macrophages is indispensable for IgG homeostasis

scientific article published on 30 April 2019

New results on the single molecule localization problem in two and three dimensions

scientific article published on August 2015

Noise suppression of point spread functions and its influence on deconvolution of three-dimensional fluorescence microscopy image sets.

scientific article

Phagocytosis of antibody-opsonized tumor cells leads to the formation of a discrete vacuolar compartment in macrophages.

scientific article published on 13 February 2018

Phase 2 study of efgartigimod, a novel FcRn antagonist, in adult patients with primary immune thrombocytopenia

scientific article published on 10 December 2019

Potential of a unique antibody gene signature to predict conversion to clinically definite multiple sclerosis.

scientific article published on 24 July 2009

Protection against experimental autoimmune encephalomyelitis generated by a recombinant adenovirus vector expressing the V beta 8.2 TCR is disrupted by coadministration with vectors expressing either IL-4 or -10.

scientific article published in January 2003

Quantitative Aspects of Single Molecule Microscopy

scientific article published in January 2015

Quantitative study of single molecule location estimation techniques

scientific article

Randomized phase 2 study of FcRn antagonist efgartigimod in generalized myasthenia gravis

scientific article published on 4 June 2019

Remote focusing multifocal plane microscopy for the imaging of 3D single molecule dynamics with cellular context

scientific article published on January 2017

Secretion of T cell receptor fragments from recombinant Escherichia coli cells

scientific article published on April 20, 1992

Selective depletion of antigen-specific antibodies for the treatment of demyelinating disease

scientific article published on 16 November 2020

Simultaneous imaging of different focal planes in fluorescence microscopy for the study of cellular dynamics in three dimensions.

scientific article

State space approach to single molecule localization in fluorescence microscopy.

scientific article

Structural snapshot of aberrant antigen presentation linked to autoimmunity: the immunodominant epitope of MBP complexed with I-Au

scientific article

T cell recognition of distinct peptide:I-Au conformers in murine experimental autoimmune encephalomyelitis.

scientific article published in September 2003

Targeting FcRn for the modulation of antibody dynamics

scientific article

Targeting FcRn for therapy: from live cell imaging to in vivo studies in mice.

scientific article

Targeting FcRn to Generate Antibody-Based Therapeutics

scientific article published on 22 August 2018

Targeting Phosphatidylserine with Calcium-Dependent Protein-Drug Conjugates for the Treatment of Cancer

scientific article published on 22 September 2017

Targeting the neonatal fc receptor for antigen delivery using engineered fc fragments.

scientific article published on December 2008

The MHC class I related Fc receptor, FcRn, is expressed in the epithelial cells of the human mammary gland.

scientific article

The MHC class I-related receptor, FcRn, plays an essential role in the maternofetal transfer of gamma-globulin in humans

scientific article (publication date: August 2001)

The central residues of a T cell receptor sequence motif are key determinants of autoantigen recognition in murine experimental autoimmune encephalomyelitis.

scientific article published in January 2005

The choice of reference cell in the analysis of kinetic data using BIAcore.

scientific article

The effect of pH dependence of antibody-antigen interactions on subcellular trafficking dynamics

scientific article

The encephalitogenic, human myelin oligodendrocyte glycoprotein-induced antibody repertoire is directed toward multiple epitopes in C57BL/6-immunized mice.

scientific article published in July 2013

The influence of signal noise on the accuracy of kinetic constants measured by surface plasmon resonance experiments

scientific article published on 01 August 1999

The level of HER2 expression is a predictor of antibody-HER2 trafficking behavior in cancer cells

scientific article published on January 2014

Transcytosis and catabolism of antibody

scientific article

Two approximations for the geometric model of signal amplification in an electron-multiplying charge-coupled device detector.

scientific article

Ultrahigh accuracy imaging modality for super-localization microscopy.

scientific article

Use of Fc-Engineered Antibodies as Clearing Agents to Increase Contrast During PET.

scientific article

Using multifocal plane microscopy to reveal novel trafficking processes in the recycling pathway

scientific article

Vaccination with a recombinant V alpha domain of a TCR prevents the development of collagen-induced arthritis ⬇️

scientific article published on November 1, 1995

Visualizing the site and dynamics of IgG salvage by the MHC class I-related receptor, FcRn.

scientific article

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