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List of works by Jonathan A Phillips

A Multiplatform Approach for the Discovery of Novel Drug-Induced Kidney Injury Biomarkers.

scientific article published on 8 September 2017

A Predominant Oxidative Renal Metabolite of Empagliflozin in Male Mice Is Cytotoxic in Mouse Renal Tubular Cells but not Genotoxic.

scientific article

A pharmaceutical industry perspective on microphysiological kidney systems for evaluation of safety for new therapies

scientific article published on 28 January 2020

Assessment of Inhibin B as a Biomarker of Testicular Injury Following Administration of Carbendazim, Cetrorelix, or 1,2‐Dibromo‐3‐Chloropropane in Wistar Han Rats ⬇️

scientific article published on January 30, 2013

Fibroblasts regulate contractile force independent of MMP activity in 3D-collagen.

scientific article published in December 2003

Identification of sperm mRNA biomarkers associated with testis injury during preclinical testing of pharmaceutical compounds.

scientific article published on 3 February 2017

Matrix metalloproteinase activity synergizes with alpha2beta1 integrins to enhance collagen remodeling.

scientific article published on October 2005

Microphysiological systems for ADME-related applications: current status and recommendations for system development and characterization

scientific article published on 14 January 2020

Navigating tissue chips from development to dissemination: A pharmaceutical industry perspective.

scientific article published in January 2017

Net Reclassification Index and Integrated Discrimination Index Are Not Appropriate for Testing Whether a Biomarker Improves Predictive Performance.

scientific article

Pathogenesis of Renal Injury and Gene Expression Changes in the Male CD-1 Mouse Associated with Exposure to Empagliflozin

scientific article published on 26 June 2018

Rat Urinary Osteopontin and Neutrophil Gelatinase-Associated Lipocalin Improve Certainty of Detecting Drug-Induced Kidney Injury.

scientific article

Renal biomarker qualification submission: a dialog between the FDA-EMEA and Predictive Safety Testing Consortium

article

Total-body irradiation of postpubertal mice with (137)Cs acutely compromises the microarchitecture of cancellous bone and increases osteoclasts.

scientific article published on March 2009

Towards consensus practices to qualify safety biomarkers for use in early drug development

article

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