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List of works by Scott W Leonard

5-nitro-gamma-tocopherol increases in human plasma exposed to cigarette smoke in vitro and in vivo.

scientific article published in December 2003

Acute Lung Injury-Induced Collagen Deposition is Associated with Elevated Asymmetric Dimethylarginine and Arginase Activity ⬇️

scientific article published on March 1, 2011

Alpha-tocopherol beta-oxidation localized to rat liver mitochondria.

scientific article published on 9 October 2009

Alpha-tocopherol modulates Cyp3a expression, increases gamma-CEHC production, and limits tissue gamma-tocopherol accumulation in mice fed high gamma-tocopherol diets.

scientific article

Alpha-tocopherol modulates genes involved in hepatic xenobiotic pathways in mice

scientific article published on 11 September 2008

Antioxidant supplementation lowers circulating IGF-1 but not F(2)-isoprostanes immediately following anterior cruciate ligament surgery.

scientific article published in January 2009

Antioxidant supplements reduced oxidative stress and stabilized liver function tests but did not reduce inflammation in a randomized controlled trial in obese children and adolescents

scientific article published on 18 December 2013

Burn and smoke inhalation injury in sheep depletes vitamin E: kinetic studies using deuterated tocopherols.

scientific article published in February 2007

Cigarette smoking increases human vitamin E requirements as estimated by plasma deuterium-labeled CEHC.

scientific article

Comparisons of plasma/serum micronutrients between Okinawan and Oregonian elders: a pilot study.

scientific article

Conjugated Linoleic Acid and Fish Oil in Laying Hen Diets: Effects on Egg Fatty Acids, Thiobarbituric Acid Reactive Substances, and Tocopherols During Storage

scientific article published on 01 May 2007

Daily Consumption of Oregon Hazelnuts Affects α-Tocopherol Status in Healthy Older Adults: A Pre-Post Intervention Study

scientific article published on 01 December 2018

Deuterium-labeled phylloquinone fed to α-tocopherol-injected rats demonstrates sensitivity of low phylloquinone-containing tissues to menaquinone-4 depletion

scientific article

Dietary zinc restriction in rats alters antioxidant status and increases plasma F2 isoprostanes

scientific article published on 04 December 2006

Enhanced inflammatory responses in alpha-tocopherol transfer protein null mice.

scientific article published in March 2004

Faster plasma vitamin E disappearance in smokers is normalized by vitamin C supplementation.

scientific article published on 15 November 2005

Gamma-tocopherol supplementation alone and in combination with alpha-tocopherol alters biomarkers of oxidative stress and inflammation in subjects with metabolic syndrome.

scientific article published on 23 December 2007

Gene-nutrient interactions exemplified by the alpha-tocopherol content of tissues from alpha-tocopherol transfer protein-null mice fed different dietary vitamin E concentrations.

scientific article

Genome wide responses of murine lungs to dietary alpha-tocopherol

scientific article published on January 2007

High-Dietary Alpha-Tocopherol or Mixed Tocotrienols Have No Effect on Bone Mass, Density, or Turnover in Male Rats During Skeletal Maturation

scientific article published on 6 April 2017

Human vitamin E requirements assessed with the use of apples fortified with deuterium-labeled alpha-tocopheryl acetate.

scientific article

Increased static and decreased capacity oxidation-reduction potentials in plasma are predictive of metabolic syndrome

scientific article (publication date: 14 February 2017)

Increased vitamin E intake is associated with higher alpha-tocopherol concentration in the maternal circulation but higher alpha-carboxyethyl hydroxychroman concentration in the fetal circulation.

scientific article

Lower plasma alpha-carboxyethyl-hydroxychroman after deuterium-labeled alpha-tocopherol supplementation suggests decreased vitamin E metabolism in smokers

scientific article published on 01 May 2005

Metabolic syndrome increases dietary α-tocopherol requirements as assessed using urinary and plasma vitamin E catabolites: a double-blind, crossover clinical trial.

scientific article published on 11 January 2017

Novel function of vitamin E in regulation of zebrafish (Danio rerio) brain lysophospholipids discovered using lipidomics.

scientific article published on 8 April 2015

Quantitation of rat liver vitamin E metabolites by LC-MS during high-dose vitamin E administration.

scientific article

Regulation of the alpha-tocopherol transfer protein in mice: lack of response to dietary vitamin E or oxidative stress.

scientific article published in February 2006

Regulatory mechanisms to control tissue alpha-tocopherol.

scientific article published on 31 May 2007

Resistance of young rat hepatic mitochondria to bile acid-induced permeability transition: potential role of alpha-tocopherol

scientific article

Response to Harri Hemilä, “Conclusions about intervention effects should not be based on surrogate end points”

scientific article published on 01 February 2007

Sex differences in the inhibition of gamma-tocopherol metabolism by a single dose of dietary sesame oil in healthy subjects.

scientific article published on June 2008

Stability of antioxidant vitamins in whole human blood during overnight storage at 4°C and frozen storage up to 6 months

scientific article published on 01 June 2018

Studies in humans using deuterium-labeled alpha- and gamma-tocopherols demonstrate faster plasma gamma-tocopherol disappearance and greater gamma-metabolite production.

scientific article

Three non-allelic epistatically interacting methyltransferase mutations produce novel tocopherol (vitamin E) profiles in sunflower

scientific article published on 04 August 2006

Vitamin E absorption and kinetics in healthy women, as modulated by food and by fat, studied using 2 deuterium-labeled α-tocopherols in a 3-phase crossover design

scientific article published on 01 November 2019

Vitamin E and C supplementation does not ameliorate muscle dysfunction after anterior cruciate ligament surgery.

scientific article published on 12 September 2009

Vitamin E bioavailability from fortified breakfast cereal is greater than that from encapsulated supplements.

scientific article published in January 2004

Vitamin E decreases extra-hepatic menaquinone-4 concentrations in rats fed menadione or phylloquinone.

scientific article published in June 2012

Vitamin E delivery to human skin: studies using deuterated alpha-tocopherol measured by APCI LC-MS.

scientific article

Vitamin E status and metabolism in adult and aged aryl hydrocarbon receptor null mice.

scientific article

Vitamin E supplementation increases circulating vitamin E metabolites tenfold in end-stage renal disease patients.

scientific article published in August 2003

Vitamin e kinetics and the function of tocopherol regulatory proteins ⬇️

scientific article published on October 1, 2001

Vitamins C and E improve regrowth and reduce lipid peroxidation of blackberry shoot tips following cryopreservation.

scientific article published on 7 November 2009

Vitamins E and C modulate the association between reciprocally regulated cytokines after an anterior cruciate ligament injury and surgery.

scientific article published in August 2011

Zinc deficiency affects DNA damage, oxidative stress, antioxidant defenses, and DNA repair in rats.

scientific article

α-Tocopherol injections in rats up-regulate hepatic ABC transporters, but not cytochrome P450 enzymes

scientific article published on 3 September 2011

α-Tocopherol regulation of hepatic cytochrome P450s and ABC transporters in rats

scientific article published on 04 July 2006

α-Tocopherol supplementation reduces 5-nitro-γ-tocopherol accumulation by decreasing γ-tocopherol in young adult smokers

scientific article published on 12 May 2015

ω-Hydroxylation of phylloquinone by CYP4F2 is not increased by α-tocopherol.

scientific article published on 03 May 2013

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