List of works by David Meyre

A Candidate-Gene Approach Identifies Novel Associations Between Common Variants in/Near Syndromic Obesity Genes and BMI in Pediatric and Adult European Populations

scientific article published on 28 January 2019

A POMC variant implicates beta-melanocyte-stimulating hormone in the control of human energy balance

scientific article published in February 2006

A Rare Variant in the Visfatin Gene (NAMPT/PBEF1) Is Associated With Protection From Obesity

article

A genetic link between prepregnancy body mass index, postpartum weight retention, and offspring weight in early childhood.

scientific article published on 24 November 2016

A genome-wide association meta-analysis identifies new childhood obesity loci

scientific article

A genome-wide association search for type 2 diabetes genes in African Americans

scientific article published on 4 January 2012

A genome-wide association study identifies novel risk loci for type 2 diabetes

scientific article

A genome-wide association study identifies rs2000999 as a strong genetic determinant of circulating haptoglobin levels

scientific article (publication date: 2012)

A genome-wide scan for childhood obesity-associated traits in French families shows significant linkage on chromosome 6q22.31-q23.2.

scientific article

A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels

scientific article published in May 2008

A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity

scientific article published on 01 October 2019

A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk

scientific article

ACDC/Adiponectin Polymorphisms Are Associated With Severe Childhood and Adult Obesity

scientific article published on 01 February 2006

Adiponectin is associated with cardio-metabolic traits in Mexican children

scientific article published on 28 February 2019

Adiponectin, type 2 diabetes and the metabolic syndrome: lessons from human genetic studies

scientific article

Analysis of novel risk loci for type 2 diabetes in a general French population: the D.E.S.I.R. study

scientific article

Analysis of the SIM1 contribution to polygenic obesity in the French population

scientific article

Analysis of the contribution of FTO, NPC1, ENPP1, NEGR1, GNPDA2 and MC4R genes to obesity in Mexican children.

scientific article

Assessing the Heritability of Complex Traits in Humans: Methodological Challenges and Opportunities

scientific article

Assessing the effects of 35 European-derived BMI-associated SNPs in Mexican children.

scientific article published on 3 August 2016

Association analysis indicates that a variant GATA-binding site in the PIK3CB promoter is a Cis-acting expression quantitative trait locus for this gene and attenuates insulin resistance in obese children

scientific article published on 31 October 2007

Association between PPAR-γ2 Pro12Ala genotype and insulin resistance is modified by circulating lipids in Mexican children

scientific article published on 14 April 2016

Association of AMY1A/AMY2A copy numbers and AMY1/AMY2 serum enzymatic activity with obesity in Mexican children

scientific article published on 20 April 2020

Association of Melanin-Concentrating Hormone Receptor 1 5' Polymorphism With Early-Onset Extreme Obesity

scientific article published on 26 September 2005

Association of gut microbiome with fasting triglycerides, fasting insulin and obesity status in Mexican children

scientific article published on 15 November 2020

Association studies on ghrelin and ghrelin receptor gene polymorphisms with obesity

scientific article published on 22 January 2009

Bardet-Biedl syndrome gene variants are associated with both childhood and adult common obesity in French Caucasians.

scientific article published in October 2006

Benefits and limitations of genome-wide association studies

scientific article published on 01 August 2019

Blood CSF1 and CXCL12 as Causal Mediators of Coronary Artery Disease

scientific article published on 09 July 2018

Causal association of haptoglobin with obesity in Mexican children: a Mendelian randomization study

scientific article published on 20 April 2020

Causal relationship between adiponectin and metabolic traits: a Mendelian randomization study in a multiethnic population

scientific article

Childhood obesity is associated with shorter leukocyte telomere length

scientific article

Combined effects of MC4R and FTO common genetic variants on obesity in European general populations.

scientific article published on 3 March 2009

Comment on "A Common Genetic Variant Is Associated with Adult and Childhood Obesity"

scientific article published in Science

Comment on: Valette et al. Melanocortin-4 receptor mutations and polymorphisms do not affect weight loss after bariatric surgery. PLOS ONE 2012; 7(11):E48221.

scientific article

Common nonsynonymous variants in PCSK1 confer risk of obesity

article

Common variants in FTO, MC4R, TMEM18, PRL, AIF1, and PCSK1 show evidence of association with adult obesity in the Greek population

scientific article

Common variants near BDNF and SH2B1 show nominal evidence of association with snacking behavior in European populations

scientific article published on 3 May 2013

Common variants near MC4R are associated with fat mass, weight and risk of obesity

scientific article

Common variation in SIM1 is reproducibly associated with BMI in Pima Indians

scientific article published on 28 April 2009

Comprehensive identification of pleiotropic loci for body fat distribution using the NHGRI-EBI Catalog of published genome-wide association studies

scientific article published on 22 November 2018

Concordance of two multiple analytical approaches demonstrate that interaction between BMI and ADIPOQ haplotypes is a determinant of LDL cholesterol in a general French population

scientific article

Contribution of common non-synonymous variants in PCSK1 to body mass index variation and risk of obesity: a systematic review and meta-analysis with evidence from up to 331 175 individuals

scientific article

Contribution of rare coding mutations in CD36 to type 2 diabetes and cardio-metabolic complications

scientific article published on 20 November 2019

Does genetic heterogeneity account for the divergent risk of type 2 diabetes in South Asian and white European populations?

scientific article

Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human

scientific journal article

Early detrimental metabolic outcomes of rs17300539-A allele of ADIPOQ gene despite higher adiponectinemia

scientific article published on 5 November 2009

Eating Behavior, Low-Frequency Functional Mutations in the Melanocortin-4 Receptor (MC4R) Gene, and Outcomes of Bariatric Operations: A 6-Year Prospective Study

scientific article

Effect of living arrangement on anthropometric traits in first-year university students from Canada: The GENEiUS study

scientific article published on 06 November 2020

Effect of sex/gender on obesity traits in Canadian first year university students: The GENEiUS study

scientific article published in 2021

Effects of TCF7L2 polymorphisms on obesity in European populations

scientific article published on February 2008

Endocannabinoid receptor 1 gene variations increase risk for obesity and modulate body mass index in European populations

scientific article published on 28 March 2008

Erratum: Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia

scholarly article by Johan Rung et al published October 2009 in Nature Genetics

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article published in May 2010

Established and emerging strategies to crack the genetic code of obesity

scientific article published on 23 October 2018

Estimation of newborn risk for child or adolescent obesity: lessons from longitudinal birth cohorts

scientific article

Evaluating the Association of FAAH Common Gene Variation with Childhood, Adult Severe Obesity and Type 2 Diabetes in the French Population

article

Evaluating the transferability of 15 European-derived fasting plasma glucose SNPs in Mexican children and adolescents

scientific article published on 26 October 2016

Evaluation of A2BP1 as an obesity gene ⬇️

scientific article

Fine-mapping of 98 obesity loci in Mexican children

scientific article published on 12 March 2018

From big data analysis to personalized medicine for all: challenges and opportunities

scientific article

Gain-of-function variants in the melanocortin 4 receptor gene confer susceptibility to binge eating disorder in subjects with obesity: a systematic review and meta-analysis

article

Genetic Study of the Melanin-Concentrating Hormone Receptor 2 in Childhood and Adulthood Severe Obesity

article by Maya Ghoussaini et al published November 2007 in The Journal of Clinical Endocrinology and Metabolism

Genetic and functional assessment of the role of the rs13431652-A and rs573225-A alleles in the G6PC2 promoter that are strongly associated with elevated fasting glucose levels.

scientific article published on 9 July 2010

Genetic contribution to lipid levels in early life based on 158 loci validated in adults: the FAMILY study.

scientific article published on 6 March 2017

Genetic contribution to waist-to-hip ratio in Mexican children and adolescents based on 12 loci validated in European adults

scientific article published on 13 March 2018

Genetic dissection of diabetes: facing the giant

scientific article published on October 2013

Genetic evidence of assortative mating in humans

article

Genetic information and the prediction of incident type 2 diabetes in a high-risk multiethnic population: the EpiDREAM genetic study

scientific article published on 19 April 2013

Genetic markers of inflammation may not contribute to metabolic traits in Mexican children.

scientific article published on 23 June 2016

Genetic variant in HK1 is associated with a proanemic state and A1C but not other glycemic control-related traits

scientific article published on 03 August 2009

Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia

scientific article published on 6 September 2009

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

scientific journal article

Genetics of Obesity: What have we Learned?

scientific article

Genome-wide Linkage Analysis for Severe Obesity in French Caucasians Finds Significant Susceptibility Locus on Chromosome 19q

article

Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention ⬇️

scientific article published on 7 September 2022

Genome-wide association scans identified CTNNBL1 as a novel gene for obesity.

scientific article

Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations

scientific article

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genomic insights into early-onset obesity

scientific article

Give GWAS a Chance

scientific article

Helicobacter pylori colonization and obesity - a Mendelian randomization study

scientific article published on 31 October 2017

Heterozygous mutations causing partial prohormone convertase 1 deficiency contribute to human obesity

scientific article published on 30 December 2011

INS VNTR is not associated with childhood obesity in 1,023 families: a family-based study

scientific article

Identification of two novel loss-of-function SIM1 mutations in two overweight children with developmental delay

scientific article published on 19 September 2014

Impact of common type 2 diabetes risk polymorphisms in the DESIR prospective study

scientific article published on 31 October 2007

Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity

scientific article

Implication of the Pro12Ala polymorphism of the PPAR-gamma 2 gene in type 2 diabetes and obesity in the French population

scientific article

Influence of depression on genetic predisposition to type 2 diabetes in a multiethnic longitudinal study

scientific article

Is glutamate decarboxylase 2 (GAD2) a genetic link between low birth weight and subsequent development of obesity in children?

scientific article published on 25 January 2005

Jumping on the Train of Personalized Medicine: A Primer for Non- Geneticist Clinicians: Part 3. Clinical Applications in the Personalized Medicine Area

scientific article

Jumping on the Train of Personalized Medicine: A Primer for Non-Geneticist Clinicians: Part 1. Fundamental Concepts in Molecular Genetics

scientific article

Jumping on the Train of Personalized Medicine: A Primer for Non-Geneticist Clinicians: Part 2. Fundamental Concepts in Genetic Epidemiology

scientific article

Lack of Association of CD36 SNPs With Early Onset Obesity: A Meta-Analysis in 9,973 European Subjects

article

Longitudinal relationships between glycemic status and body mass index in a multiethnic study: evidence from observational and genetic epidemiology

scientific article published on 02 August 2016

Loss-of-function mutation in the dioxygenase-encoding FTO gene causes severe growth retardation and multiple malformations

scientific article published on 25 June 2009

Loss-of-function mutations in MC4R are very rare in the Greek severely obese adult population

scientific article published on 26 March 2012

Loss-of-function mutations in SIM1 contribute to obesity and Prader-Willi-like features

scientific article published on 17 June 2013

Loss-of-function mutations in the melanocortin-3 receptor gene confer risk for human obesity: A systematic review and meta-analysis

scientific article published on 14 May 2019

MTNR1B G24E variant associates With BMI and fasting plasma glucose in the general population in studies of 22,142 Europeans

scientific article

Medium term post-bariatric surgery deficit of vitamin B12 is predicted by deficit at time of surgery

scientific article published on 25 April 2020

Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design?

scientific article published on 23 October 2009

Modelling of OGTT curve identifies 1 h plasma glucose level as a strong predictor of incident type 2 diabetes: results from two prospective cohorts

scientific article published on 8 October 2014

Molecular basis of obesity: current status and future prospects

scientific article

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article

No contribution of angiotensin-converting enzyme (ACE) gene variants to severe obesity: a model for comprehensive case/control and quantitative cladistic analysis of ACE in human diseases

article

Non-synonymous polymorphisms in melanocortin-4 receptor protect against obesity: the two facets of a Janus obesity gene

article

Novel association approach for variable number tandem repeats (VNTRs) identifies DOCK5 as a susceptibility gene for severe obesity

scientific article

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits

scientific article published on 12 October 2020

Obesity genes and risk of major depressive disorder in a multiethnic population: a cross-sectional study

scientific article published on December 2015

Obesity genetics in mouse and human: back and forth, and back again

scientific article

Obesity status modifies the association between rs7556897T>C in the intergenic region SLC19A3-CCL20 and blood pressure in French children

scientific article published on 01 April 2020

Parental and offspring contribution of genetic markers of adult blood pressure in early life: The FAMILY study

scientific article published on 18 October 2017

Penetrance of Polygenic Obesity Susceptibility Loci across the Body Mass Index Distribution

scientific article published in December 2017

Physical activity and genetic predisposition to obesity in a multiethnic longitudinal study

scientific article

Polymorphisms in the amino acid transporter solute carrier family 6 (neurotransmitter transporter) member 14 gene contribute to polygenic obesity in French Caucasians

scientific article

Post genome-wide association studies of novel genes associated with type 2 diabetes show gene-gene interaction and high predictive value

scientific article published in 2008

Preferential reciprocal transfer of paternal/maternal DLK1 alleles to obese children: first evidence of polar overdominance in humans.

scientific article published on 9 April 2008

Prevalence of loss-of-function FTO mutations in lean and obese individuals

scientific article

Prevalence of melanocortin-4 receptor deficiency in Europeans and their age-dependent penetrance in multigenerational pedigrees.

scientific article published on 16 June 2008

Rare genomic structural variants in complex disease: lessons from the replication of associations with obesity

scientific article

Rationale and design of GENEiUS: a prospective observational study on the genetic and environmental determinants of body mass index evolution in Canadian undergraduate students

scientific article published on 10 December 2017

Recent progress in genetics, epigenetics and metagenomics unveils the pathophysiology of human obesity

scientific article published on June 2016

Revisiting the evolutionary origins of obesity: lazy versus peppy-thrifty genotype hypothesis

scientific article published on 27 September 2018

Risk Alleles in/near ADCY5, ADRA2A, CDKAL1, CDKN2A/B, GRB10, and TCF7L2 Elevate Plasma Glucose Levels at Birth and in Early Childhood: Results from the FAMILY Study

scientific article

SREBF-1 gene polymorphisms are associated with obesity and type 2 diabetes in French obese and diabetic cohorts

scientific article published on 01 August 2004

Secretory granule neuroendocrine protein 1 (SGNE1) genetic variation and glucose intolerance in severe childhood and adult obesity

scientific article

Serum adiponectin is related to plasma high-density lipoprotein cholesterol but not to plasma insulin-concentration in healthy children: the FLVS II study

scientific article

Sex/gender modifies the association between the MC4R p.Ile269Asn mutation and type 2 diabetes in the Mexican population

scientific article published on 13 October 2020

Should we have blind faith in bioinformatics software? Illustrations from the SNAP web-based tool

scientific article

Signatures of natural selection and ethnic-specific prevalence of NPC1 pathogenic mutations contributing to obesity and Niemann-Pick disease type C1

scientific article published on 02 November 2020

Study of TNFalpha -308G/A and IL6 -174G/C polymorphisms in type 2 diabetes and obesity risk in the Tunisian population

scientific article

TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups: a global meta-analysis

scientific article published on 3 May 2007

TCF7L2 rs7903146 variant does not associate with smallness for gestational age in the French population

scientific article

TCF7L2 variation predicts hyperglycemia incidence in a French general population: the data from an epidemiological study on the Insulin Resistance Syndrome (DESIR) study

scientific article

The Melanocortin 4 Receptor p.Ile269Asn Mutation Is Associated with Childhood and Adult Obesity in Mexicans

scientific article published in April 2020

The Q121 variant of ENPP1 may protect from childhood overweight/obesity in the Italian population

scientific article

The T-381C SNP in BNP gene may be modestly associated with type 2 diabetes: an updated meta-analysis in 49 279 subjects

scientific article published on 18 April 2009

The effect of race/ethnicity on obesity traits in first year university students from Canada: The GENEiUS study

scientific article published on 25 November 2020

The extending spectrum of NPC1-related human disorders: from Niemann-Pick C1 Disease to obesity

scientific article published on 9 January 2018

The genetic susceptibility to type 2 diabetes may be modulated by obesity status: implications for association studies

scientific article

The importance of gene-environment interactions in human obesity.

scientific article

The imprinted gene neuronatin is regulated by metabolic status and associated with obesity.

scientific article

TheINSVNTR Locus Does Not Associate with Smallness for Gestational Age (SGA) but Interacts with SGA to Increase Insulin Resistance in Young Adults

scholarly article by Thuy-Ai Vu-Hong et al published June 2006 in The Journal of Clinical Endocrinology and Metabolism

Transcription Factor TCF7L2 Genetic Study in the French Population: Expression in Human -Cells and Adipose Tissue and Strong Association With Type 2 Diabetes

article

Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups

scientific journal article

Type 2 diabetes whole-genome association study in four populations: the DiaGen consortium

scientific article

Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes

scientific article published on 17 July 2005

Variation in FTO contributes to childhood obesity and severe adult obesity

scientific article

[ENPP1, the first example of common genetic link between childhood and adult obesity and type 2 diabetes].

scientific article published in March 2006

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