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List of works by Megan Othus

A Class of Semiparametric Mixture Cure Survival Models with Dependent Censoring

scientific article

A Gaussian Copula Model for Multivariate Survival Data

scientific article

A model for prediction of FLT3-ITD and NPM1 (without FLT3-ITD) positivity in patients with newly diagnosed acute myeloid leukaemia

scientific article published on 6 July 2013

A phase 2 trial of azacitidine and gemtuzumab ozogamicin therapy in older patients with acute myeloid leukemia

scientific article published on 03 October 2013

A pilot surrogate endpoint biomarker study of celecoxib in oral premalignant lesions

scientific article published in October 2008

Accounting for Cured Patients in Cost-Effectiveness Analysis

scientific article published on 9 June 2016

Addition of gemtuzumab ozogamicin to induction chemotherapy in adult patients with acute myeloid leukaemia: a meta-analysis of individual patient data from randomised controlled trials

scientific article

Adjuvant vaccine immunotherapy of resected, clinically node-negative melanoma: long-term outcome and impact of HLA class I antigen expression on overall survival

scientific article

Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid Leukemia: Time to Move Toward a Minimal Residual Disease-Based Definition of Complete Remission?

scientific article published on 14 December 2015

Arsenic trioxide during consolidation for patients with previously untreated low/intermediate risk acute promyelocytic leukaemia may eliminate the need for maintenance therapy

scientific article

Association between early promoter-specific DNA methylation changes and outcome in older acute myeloid leukemia patients

scientific article published on 15 January 2016

Central nervous system involvement in acute myeloid leukemia patients undergoing hematopoietic cell transplantation

scientific article

Change-point cure models with application to estimating the change-point effect of age of diagnosis among prostate cancer patients ⬇️

scientific article published on March 12, 2012

Clinical Experience With Modified, Single-Tube T-Cell Receptor Vβ Flow Cytometry Analysis for T-Cell Clonality

scientific article published on April 2016

Comparable Outcomes of Patients Eligible versus Ineligible for SWOG Leukemia Studies

scientific article

Comparative analysis of total body irradiation (TBI)-based and non-TBI-based myeloablative conditioning for acute myeloid leukemia in remission with or without measurable residual disease

scientific article published on 03 December 2019

Continuous versus intermittent BRAF and MEK inhibition in patients with BRAF-mutated melanoma: a randomized phase 2 trial

scientific article published on 05 October 2020

Cure Models as a Useful Statistical Tool for Analyzing Survival ⬇️

scientific article published on 06 June 2012

Cyclosporine modulation of multidrug resistance in combination with pravastatin, mitoxantrone and etoposide for adult patients with relapsed/refractory acute myeloid leukemia: a phase 1/2 study ⬇️

scientific article published on March 27, 2013

Cytogenetic heterogeneity negatively impacts outcomes in patients with acute myeloid leukemia

scientific article

Deep NPM1 Sequencing Following Allogeneic Hematopoietic Cell Transplantation Improves Risk Assessment in Adults with NPM1-Mutated AML.

scientific article published on 20 April 2018

Determinants of fatal bleeding during induction therapy for acute promyelocytic leukemia in the ATRA era.

scientific article published on 12 January 2017

Does outcome of second salvage therapy in relapsed or refractory acute myeloid leukemia depend on intensity of either first or second salvage therapy?

scientific article published on 23 December 2015

Dose to larynx predicts for swallowing complications after intensity-modulated radiotherapy

scientific article published on 28 May 2008

Early achievement of measurable residual disease (MRD)-negative complete remission as predictor of outcome after myeloablative allogeneic hematopoietic cell transplantation in acute myeloid leukemia

scientific article published on 04 November 2019

Early hospital discharge after intensive induction chemotherapy for adults with acute myeloid leukemia or other high-grade myeloid neoplasm

scientific article published on 04 October 2019

Effect of allogeneic hematopoietic cell transplantation in first complete remission on post-relapse complete remission rate and survival in acute myeloid leukemia

scientific article published on 20 March 2015

Elevated lymphocyte count at time of acute myeloid leukemia diagnosis is associated with shorter remission

scientific article

Empiric definition of eligibility criteria for clinical trials in relapsed/refractory acute myeloid leukemia: analysis of 1,892 patients from HOVON/SAKK and SWOG.

scientific article published on 9 July 2015

Failure of three novel regimens to improve outcome for patients with relapsed or refractory acute myeloid leukaemia: a report from the Eastern Cooperative Oncology Group

scientific article

Fate of patients with newly diagnosed acute myeloid leukemia who fail primary induction therapy

scientific article

Four different regimens of farnesyltransferase inhibitor tipifarnib in older, untreated acute myeloid leukemia patients: North American Intergroup Phase II study SWOG S0432.

scientific article

G-CSF priming, clofarabine, and high dose cytarabine (GCLAC) for upfront treatment of acute myeloid leukemia, advanced myelodysplastic syndrome or advanced myeloproliferative neoplasm

scientific article

High frequency of brain metastases after adjuvant therapy for high-risk melanoma

scientific article published on 10 October 2017

Impact of Specimen Heterogeneity on Biomarkers in Repository Samples from Patients with Acute Myeloid Leukemia: A SWOG Report

scientific article published on 27 November 2017

Impact of body-mass index on the outcome of adult patients with acute myeloid leukemia

scientific article

Impact of pretransplant measurable residual disease on the outcome of allogeneic hematopoietic cell transplantation in adult monosomal karyotype AML

scientific article published on 23 January 2020

Impact of residual normal metaphases in core binding factor acute myeloid leukemia ⬇️

scientific article published on September 16, 2011

Influence of obesity on efficacy and toxicity of induction chemotherapy in patients with newly diagnosed acute myeloid leukemia ⬇️

scientific article published on August 22, 2012

Influence of residual normal metaphases in acute myeloid leukemia patients with monosomal karyotype ⬇️

scientific article published on February 17, 2011

Information time scales for interim analyses of randomized clinical trials

scientific article

Infusion of a non-HLA-matched ex-vivo expanded cord blood progenitor cell product after intensive acute myeloid leukaemia chemotherapy: a phase 1 trial

scientific article published on 7 June 2016

NUP98/NSD1 and FLT3/ITD coexpression is more prevalent in younger AML patients and leads to induction failure: a COG and SWOG report

scientific article

Next-Generation Sequencing in Adult B Cell Acute Lymphoblastic Leukemia Patients

scientific article published on 3 January 2017

Outcome of adolescents and young adults with acute myeloid leukemia treated on COG trials compared to CALGB and SWOG trials

scientific article published on 19 September 2013

Outcome of patients with acute myeloid leukemia with monosomal karyotype who undergo hematopoietic cell transplantation ⬇️

scientific article published on June 16, 2011

Outcomes of patients with stage III nonsmall cell lung cancer treated with chemotherapy and radiation with and without surgery

scientific article published on September 2009

Phase 1/2 trial of cladribine, high-dose cytarabine, mitoxantrone, and G-CSF with dose-escalated mitoxantrone for relapsed/refractory acute myeloid leukemia or other high-grade myeloid neoplasms

scholarly article by Anna B Halpern et al published 8 November 2018 in Haematologica

Phase 2 study of RO4929097, a gamma-secretase inhibitor, in metastatic melanoma: SWOG 0933.

scientific article

Phase II trial of sorafenib in combination with carboplatin and paclitaxel in patients with metastatic uveal melanoma: SWOG S0512 ⬇️

scientific article published on November 30, 2012

Prediction of adverse events during intensive induction chemotherapy for acute myeloid leukemia or high-grade myelodysplastic syndromes

scientific article

Prediction of early death after induction therapy for newly diagnosed acute myeloid leukemia with pretreatment risk scores: a novel paradigm for treatment assignment

scientific article published on 3 October 2011

Prediction of early death in adults with relapsed or refractory acute myeloid leukemia

scientific article published on 11 January 2016

Prognostic impact of monosomal karyotype in young adult and elderly acute myeloid leukemia: the Southwest Oncology Group (SWOG) experience

scientific article published on 18 June 2010

Prognostic methylation markers for overall survival in cytogenetically normal patients with acute myeloid leukemia treated on SWOG trials

scientific article published on 21 February 2017

Prognostic significance of NPM1 mutations in the absence of FLT3-internal tandem duplication in older patients with acute myeloid leukemia: a SWOG and UK National Cancer Research Institute/Medical Research Council report

scientific article

Quality of life from the perspective of the patient with acute myeloid leukemia

scientific article published on 7 September 2017

Randomized Phase II Study of Azacitidine Alone or in Combination With Lenalidomide or With Vorinostat in Higher-Risk Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia: North American Intergroup Study SWOG S1117.

scientific article

Randomized Phase II Trial of Sorafenib with Temsirolimus or Tipifarnib in Untreated Metastatic Melanoma (S0438) ⬇️

scientific article published on January 6, 2012

Randomized phase II study of two schedules of flavopiridol given as timed sequential therapy with cytosine arabinoside and mitoxantrone for adults with newly diagnosed, poor-risk acute myelogenous leukemia ⬇️

scientific article published on June 24, 2012

Recent drug approvals for newly diagnosed acute myeloid leukemia: gifts or a Trojan horse?

scientific article published on 08 January 2020

Regimen-intensity per count-recovery and hospitalization index: A new tool to assign regimen intensity for AML

scientific article published on 24 July 2020

Relationship between event-free survival and overall survival in acute myeloid leukemia: a report from SWOG, HOVON/SAKK, and MRC/NCRI.

scientific article published on 24 March 2016

Relative survival following response to 7 + 3 versus azacytidine is similar in acute myeloid leukemia and high-risk myelodysplastic syndromes: an analysis of four SWOG studies

scientific article published on 12 October 2018

Report of the relapsed/refractory cohort of SWOG S0919: A phase 2 study of idarubicin and cytarabine in combination with pravastatin for acute myelogenous leukemia (AML).

scientific article published on 31 January 2018

Resource Utilization and Safety of Outpatient Management Following Intensive Induction or Salvage Chemotherapy for Acute Myeloid Leukemia or Myelodysplastic Syndrome: A Nonrandomized Clinical Comparative Analysis

scientific article

SWOG S0910: a phase 2 trial of clofarabine/cytarabine/epratuzumab for relapsed/refractory acute lymphocytic leukaemia

scientific article

SWOG0919: a Phase 2 study of idarubicin and cytarabine in combination with pravastatin for relapsed acute myeloid leukaemia

scientific article

Significance of FAB subclassification of "acute myeloid leukemia, NOS" in the 2008 WHO classification: analysis of 5848 newly diagnosed patients

scientific article published on 16 January 2013

Southwest Oncology Group S0008: a phase III trial of high-dose interferon Alfa-2b versus cisplatin, vinblastine, and dacarbazine, plus interleukin-2 and interferon in patients with high-risk melanoma--an intergroup study of cancer and leukemia Group

scientific article

Statistics and measurable residual disease (MRD) testing: uses and abuses in hematopoietic cell transplantation

scientific article published on 30 October 2019

Tumor volume is a prognostic factor in non-small-cell lung cancer treated with chemoradiotherapy

scientific article published on 03 June 2010

Unsatisfactory efficacy in randomized study of reduced-dose CPX-351 for medically less fit adults with newly diagnosed acute myeloid leukemia or other high-grade myeloid neoplasm

scientific article published on 14 December 2017

Unsuccessful diagnostic cytogenetic analysis is a poor prognostic feature in acute myeloid leukaemia

scientific article

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