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List of works by Andreas Bechthold

A Potential Biocontrol Agent AC12AB for Managing Potato Common Scab ⬇️

article by Arslan Sarwar et al published 2019 in Frontiers in Microbiology

A bacterial glycosyltransferase gene toolbox: generation and applications

scientific article published on 24 June 2009

A cryptic polyene biosynthetic gene cluster in Streptomyces calvus is expressed upon complementation with a functional bldA gene

scientific article

A genomic screening approach to the structure-guided identification of drug candidates from natural sources

scientific article published in May 2007

A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis

scientific article

A transposon-based strategy to identify the regulatory gene network responsible for landomycin E biosynthesis

scientific article

An influence of the copy number of biosynthetic gene clusters on the production level of antibiotics in a heterologous host

scientific article published on 2 June 2016

Aranciamycin analogs generated by combinatorial biosynthesis show improved antitumor activity

scientific article

Bacillus cereus efflux protein BC3310 - a multidrug transporter of the unknown major facilitator family, UMF-2. ⬇️

scientific article published on 12 October 2015

Biological Control of Potato Common Scab With Rare Isatropolone C Compound Produced by Plant Growth Promoting Streptomyces A1RT. ⬇️

scientific article

Biosynthesis of Rishirilide B.

scientific article

Biosynthesis of the Fluorinated Natural Product Nucleocidin in Streptomyces calvus Is Dependent on the bldA-Specified Leu-tRNA(UUA) Molecule

scientific article

Biosynthesis of the terpene phenalinolactone in Streptomyces sp. Tü6071: analysis of the gene cluster and generation of derivatives

scientific article published in April 2006

Chapter 12. The power of glycosyltransferases to generate bioactive natural compounds

scientific article published in January 2009

Characterization and analysis of the regulatory network involved in control of lipomycin biosynthesis in Streptomyces aureofaciens Tü117.

scientific article published on 8 July 2009

Characterization of representative rpoB gene mutations leading to a significant change in toyocamycin production of Streptomyces diastatochromogenes 1628.

scientific article published on 20 January 2016

Cloning and heterologous expression of the aranciamycin biosynthetic gene cluster revealed a new flexible glycosyltransferase

scientific article published on April 2007

Cloning and heterologous expression of three type II PKS gene clusters from Streptomyces bottropensis

scientific article

Cloning and sequencing of the biosynthetic gene cluster for saquayamycin Z and galtamycin B and the elucidation of the assembly of their saccharide chains

scientific article published in May 2009

Combinatorial and synthetic biosynthesis in actinomycetes

scientific article published on January 2010

Complete genome sequence of Saccharothrix espanaensis DSM 44229(T) and comparison to the other completely sequenced Pseudonocardiaceae

scientific article

Complete genome sequence of producer of the glycopeptide antibiotic Aculeximycin Kutzneria albida DSM 43870T, a representative of minor genus of Pseudonocardiaceae ⬇️

scientific article

Coordination of export and glycosylation of landomycins in Streptomyces cyanogenus S136.

scientific article published on 4 June 2008

Crystal Structure of the Avilamycin Resistance-conferring Methyltransferase AviRa from Streptomyces viridochromogenes ⬇️

scientific article (publication date: 23 May 2003)

Deoxysugars in bioactive natural products: development of novel derivatives by altering the sugar pattern

scientific article published in January 2008

Development of intergeneric conjugal gene transfer system in Streptomyces diastatochromogenes 1628 and its application for improvement of toyocamycin production

scientific article

Differences in the substrate specificity of glycosyltransferases involved in landomycins A and E biosynthesis

scientific article

Early Steps in the Biosynthetic Pathway of Rishirilide B

scientific article published on 23 April 2020

Engineered urdamycin glycosyltransferases are broadened and altered in substrate specificity

scientific article

Engineering a function into a glycosyltransferase

scientific article published in January 2009

Exploiting Pseudomonas putida for drug development

scientific article

Features and applications of bacterial glycosyltransferases: current state and prospects

scientific article published on 06 September 2008

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028.

scientific article published on 13 January 2017

Function of lanGT3, a glycosyltransferase gene involved in landomycin A biosynthesis

scientific article published in November 2004

Functional characterization of different ORFs including luciferase-like monooxygenase genes from the mensacarcin gene cluster

scientific article published on 23 April 2015

Functional expression of the Cre recombinase in actinomycetes

scientific article

Functions of genes and enzymes involved in phenalinolactone biosynthesis

scientific article published in July 2010

Generation of Streptomyces globisporus SMY622 strain with increased landomycin E production and it's initial characterization

scientific article

Generation of new landomycins with altered saccharide patterns through over-expression of the glycosyltransferase gene lanGT3 in the biosynthetic gene cluster of landomycin A in Streptomyces cyanogenus S-136.

scientific article

Generation of novel landomycins M and O through targeted gene disruption

scientific article

Genes and enzymes involved in bacterial isoprenoid biosynthesis

scientific article

Genes encoding enzymes responsible for biosynthesis of L-lyxose and attachment of eurekanate during avilamycin biosynthesis

scientific article published in October 2005

Genes involved in formation and attachment of a two-carbon chain as a component of eurekanate, a branched-chain sugar moiety of avilamycin A.

scientific article

Genome sequence of Streptomyces sp. strain Tü6071.

scientific article published on 24 June 2011

Glycosyltransferases involved in the biosynthesis of biologically active natural products that contain oligosaccharides

scientific article published on 23 June 2005

Glycosyltransferases, important tools for drug design

scientific article published on January 2008

Heterologous expression and genetic engineering of the phenalinolactone biosynthetic gene cluster by using red/ET recombineering

scientific article published in February 2008

Identification and Characterization of a Novel N- and O-Glycosyltransferase from Saccharopolyspora erythraea

scientific article published on 27 July 2020

Identification of the function of gene lndM2 encoding a bifunctional oxygenase-reductase involved in the biosynthesis of the antitumor antibiotic landomycin E by Streptomyces globisporus 1912 supports the originally assigned structure for landomycin ⬇️

scientific article

Impact of otrA expression on morphological differentiation, actinorhodin production, and resistance to aminoglycosides in Streptomyces coelicolor M145 ⬇️

Insights into the bioactivity of mensacarcin and epoxide formation by MsnO8

scientific article

It works: combinatorial biosynthesis for generating novel glycosylated compounds

scientific article published in October 2005

Iteratively acting glycosyltransferases involved in the hexasaccharide biosynthesis of landomycin A.

scientific article published in July 2005

LanGT2 Catalyzes the First Glycosylation Step during landomycin A biosynthesis

scientific article published in August 2005

LanV, a bifunctional enzyme: aromatase and ketoreductase during landomycin A biosynthesis

scientific article

Marker removal from actinomycetes genome using Flp recombinase

scientific article published on 29 April 2008

Minimum Information about a Biosynthetic Gene cluster.

scientific article published on August 2015

New Simocyclinones: Surprising Evolutionary and Biosynthetic Insights

scientific article published on 25 November 2015

Novel avilamycin derivatives with improved polarity generated by targeted gene disruption ⬇️

scientific article

Novel natural compounds obtained by genome-based screening and genetic engineering.

scientific article

On the acceptor substrate of C-glycosyltransferase UrdGT2: three prejadomycin C-Glycosides from an engineered mutant of Streptomyces globisporus 1912 DeltalndE(urdGT2).

scientific article

Organisation of the biosynthetic gene cluster and tailoring enzymes in the biosynthesis of the tetracyclic quinone glycoside antibiotic polyketomycin

scientific article

Overexpression of ribosome recycling factor is responsible for improvement of nucleotide antibiotic-toyocamycin in Streptomyces diastatochromogenes 1628.

scientific article

Oxidative Carbon Backbone Rearrangement in Rishirilide Biosynthesis

scientific article published on 19 March 2020

Rational Design of Hybrid Natural Products by Utilizing the Promiscuity of an Amide Synthetase

scientific article published on 06 August 2019

Rational Design of an Aryl-C-Glycoside Catalyst from a Natural Product O-Glycosyltransferase ⬇️

scientific article published on April 22, 2011

Rational saccharide extension by using the natural product glycosyltransferase LanGT4.

scientific article published in March 2004

Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways

scientific article published in May 2002

Selection of an efficient promoter and its application in toyocamycin production improvement in Streptomyces diastatochromogenes 1628.

scientific article published on 5 January 2017

SimReg1 is a master switch for biosynthesis and export of simocyclinone D8 and its precursors

scientific article published on 3 January 2012

Site-specific recombination strategies for engineering actinomycete genomes

scientific article published on 13 January 2012

SnoaW/SnoaL2: A Different Two-Component Monooxygenase ⬇️

scientific article published on May 25, 2012

Structural characterization of O- and C-glycosylating variants of the landomycin glycosyltransferase LanGT2

scientific article published on 7 January 2015

Structure and action of the C-C bond-forming glycosyltransferase UrdGT2 involved in the biosynthesis of the antibiotic urdamycin

scientific article

Structure and function of the antibiotic resistance-mediating methyltransferase AviRb from Streptomyces viridochromogenes

scientific article

Thailandins A and B, New Polyene Macrolactone Compounds Isolated from Actinokineospora bangkokensis Strain 44EHW(T), Possessing Antifungal Activity against Anthracnose Fungi and Pathogenic Yeasts

scientific article published on 7 June 2016

The C-Glycosyltransferase UrdGT2 is unselective toward d- and l-configured nucleotide-bound rhodinoses

scientific article published in April 2003

The Draft Genome Sequence of Actinokineospora bangkokensis 44EHWT Reveals the Biosynthetic Pathway of the Antifungal Thailandin Compounds with Unusual Butylmalonyl-CoA Extender Units

scientific article published on 23 November 2016

The Gene bldA, a regulator of morphological differentiation and antibiotic production in streptomyces

scientific article published on 27 April 2015

The active conformation of avilamycin A is conferred by AviX12, a radical AdoMet enzyme

scientific article published on 14 March 2006

The avilamycin resistance determinants AviRa and AviRb methylate 23S rRNA at the guanosine 2535 base and the uridine 2479 ribose

scientific article

The future of natural products as a source of new antibiotics.

scientific article published on August 2007

The glycosyltransferase UrdGT2 catalyzes both C- and O-glycosidic sugar transfers

scientific article

Tracking down biotransformation to the genetic level: identification of a highly flexible glycosyltransferase from Saccharothrix espanaensis

scientific article published on 21 June 2013

Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork

scientific article published on 22 November 2006

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