List of works by Alexander Meissner

A comparison of genetically matched cell lines reveals the equivalence of human iPSCs and ESCs

scientific article

A comparison of non-integrating reprogramming methods

scientific article

A model for genetic and epigenetic regulatory networks identifies rare pathways for transcription factor induced pluripotency

scientific article

A qPCR ScoreCard quantifies the differentiation potential of human pluripotent stem cells

scientific article published on 26 October 2015

A unique regulatory phase of DNA methylation in the early mammalian embryo

scientific article published on 28 March 2012

Alexander Meissner: learning the reprogramming code

scientific article published on August 2009

Analysing human neural stem cell ontogeny by consecutive isolation of Notch active neural progenitors

scientific article

Association of Brain DNA methylation in SORL1, ABCA7, HLA-DRB5, SLC24A4, and BIN1 with pathological diagnosis of Alzheimer disease

scientific article

Association of DNA methylation in the brain with age in older persons is confounded by common neuropathologies

scientific article

Author Correction: Global delay in nascent strand DNA methylation.

scientific article published on 26 March 2018

Automated, high-throughput derivation, characterization and differentiation of induced pluripotent stem cells

scientific article

Browsing (Epi)genomes: a guide to data resources and epigenome browsers for stem cell researchers

scientific article

Cancer-Germline Antigen Expression Discriminates Clinical Outcome to CTLA-4 Blockade.

scientific article published on 6 April 2018

Charting a dynamic DNA methylation landscape of the human genome

scientific article published on 07 August 2013

Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications.

scientific article

Corrigendum: DNA methylation signatures link prenatal famine exposure to growth and metabolism

scientific article published on 7 July 2015

Coverage recommendations for methylation analysis by whole-genome bisulfite sequencing

scientific article

Cre-lox-regulated conditional RNA interference from transgenes

scientific article

DNA methylation dynamics during in vivo differentiation of blood and skin stem cells

scientific article published on 26 July 2012

DNA methylation dynamics of the human preimplantation embryo

scientific article

DNA methylation signatures link prenatal famine exposure to growth and metabolism

scientific article

DUSP9 Modulates DNA Hypomethylation in Female Mouse Pluripotent Stem Cells

scientific article

Derepression of BDNF Transcription Involves Calcium-Dependent Phosphorylation of MeCP2 ⬇️

scientific article published on October 31, 2003

Derivation and manipulation of murine embryonic stem cells.

scientific article published in January 2009

Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells

scientific article published on 27 August 2007

Dissecting the Functional Consequences of De Novo DNA Methylation Dynamics in Human Motor Neuron Differentiation and Physiology.

scientific article published on 14 March 2018

Dnmt3a is essential for hematopoietic stem cell differentiation

scientific article

Dynamic single-cell imaging of direct reprogramming reveals an early specifying event

scientific article

Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells

scientific article

Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells.

scientific article

Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia

scientific article published on 15 May 2019

Epigenetic hierarchy governing Nestin expression

scientific article published on May 2009

Epigenetic modifications in pluripotent and differentiated cells ⬇️

scientific article published on October 1, 2010

Epigenetic obstacles encountered by transcription factors: reprogramming against all odds

scientific article published on 23 August 2012

Epigenetic predisposition to reprogramming fates in somatic cells

scientific article published on 18 January 2015

Epigenetic regulation of pluripotency

scientific article published on January 2010

Epigenetic restriction of extraembryonic lineages mirrors the somatic transition to cancer

scientific article published on 20 September 2017

Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal

scientific article

Epigenomics and chromatin dynamics

scientific article published on 24 February 2012

Erosion of dosage compensation impacts human iPSC disease modeling

scientific article published on May 2012

Extensive Regulatory Changes in Genes Affecting Vocal and Facial Anatomy Separate Modern from Archaic Humans

article

Gel-free multiplexed reduced representation bisulfite sequencing for large-scale DNA methylation profiling

scientific article

Generation of organized anterior foregut epithelia from pluripotent stem cells using small molecules

scientific article

Genetic and Epigenetic Variation, but Not Diet, Shape the Sperm Methylome

scientific article

Genome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution

scientific article published on 10 January 2010

Genome-scale DNA methylation maps of pluripotent and differentiated cells

scientific article

Genome-wide chromatin state transitions associated with developmental and environmental cues

scientific article

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

scientific article

Genome-wide tracking of dCas9-methyltransferase footprints

scientific article published on 9 February 2018

Genomic distribution and inter-sample variation of non-CpG methylation across human cell types

scientific article

Global DNA demethylation during mouse erythropoiesis in vivo

scientific article published on November 2011

Global delay in nascent strand DNA methylation.

scientific article published on 12 March 2018

Ground State Conditions Induce Rapid Reorganization of Core Pluripotency Factor Binding before Global Epigenetic Reprogramming

scientific article published on 29 July 2015

Guiding DNA methylation.

scientific article

High-throughput bisulfite sequencing in mammalian genomes

scientific article published on 12 May 2009

Highly efficient derivation of ventricular cardiomyocytes from induced pluripotent stem cells with a distinct epigenetic signature

scientific article

Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA.

scientific article

Identification of novel imprinted differentially methylated regions by global analysis of human-parthenogenetic-induced pluripotent stem cells

scientific article published on 4 June 2013

In vivo Monitoring of Transcriptional Dynamics After Lower-Limb Muscle Injury Enables Quantitative Classification of Healing

scientific article

In vivo control of CpG and non-CpG DNA methylation by DNA methyltransferases

scientific article

Induced Pluripotent Stem Cell Differentiation Enables Functional Validation of GWAS Variants in Metabolic Disease

scientific article published on April 2017

Induced pluripotent stem cells: current progress and potential for regenerative medicine

scientific article published on 21 January 2009

Integrative Analyses of Human Reprogramming Reveal Dynamic Nature of Induced Pluripotency

scientific article published in July 2015

In Vivo and in vitro dynamics of undifferentiated embryonic cell transcription factor 1.

scientific article published on 20 February 2014

KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance

LKB1 loss links serine metabolism to DNA methylation and tumorigenesis

scientific article published on 31 October 2016

Locally disordered methylation forms the basis of intratumor methylome variation in chronic lymphocytic leukemia

scientific article

Mammalian nuclear transfer

scientific article published on September 2006

Molecular features of cellular reprogramming and development

scientific article published on 17 February 2016

Molecular pathological epidemiology of epigenetics: emerging integrative science to analyze environment, host, and disease

scientific article

Mouse ooplasm confers context-specific reprogramming capacity

scientific article

Notch inhibition allows oncogene-independent generation of iPS cells

scientific article

PRC2 Is Required to Maintain Expression of the Maternal Gtl2-Rian-Mirg Locus by Preventing De Novo DNA Methylation in Mouse Embryonic Stem Cells

scientific article published on 19 August 2015

Paternally induced transgenerational environmental reprogramming of metabolic gene expression in mammals

scientific article

Paying PIs from grants blocks talent and diversity

scientific article published in Nature

Pluripotency factors in embryonic stem cells regulate differentiation into germ layers

scientific article

Preparation of reduced representation bisulfite sequencing libraries for genome-scale DNA methylation profiling

scientific article

Probabilistic Modeling of Reprogramming to Induced Pluripotent Stem Cells

scientific article published on December 2016

Proliferation-dependent alterations of the DNA methylation landscape underlie hematopoietic stem cell aging

scientific article published on 14 February 2013

Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells

scientific article

Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation

scientific article published on February 2008

RRBSMAP: a fast, accurate and user-friendly alignment tool for reduced representation bisulfite sequencing

scientific article published on 6 December 2011

Recommendations for the design and analysis of epigenome-wide association studies

scientific article published on October 2013

Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis

scientific article

Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines

scientific article

Reprogramming factor expression initiates widespread targeted chromatin remodeling

scientific article

Saturation analysis for whole-genome bisulfite sequencing data

scientific article

Sequential ChIP-bisulfite sequencing enables direct genome-scale investigation of chromatin and DNA methylation cross-talk

scientific article

Somatic cell nuclear transfer and derivation of embryonic stem cells in the mouse

scientific article published on 02 June 2008

Sprouty-2 regulates oncogenic K-ras in lung development and tumorigenesis

scientific article published on March 2007

Suppression of intestinal neoplasia by deletion of Dnmt3b

scientific article

Targeted bisulfite sequencing of the dynamic DNA methylome

scientific article published on 3 December 2016

Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells

scientific article published on 30 March 2015

Targets and genomic constraints of ectopic Dnmt3b expression

Tet1 regulates adult hippocampal neurogenesis and cognition

scientific article published on 13 June 2013

The simplest explanation: passive DNA demethylation in PGCs

scientific article published on 8 January 2013

The use of small molecules in somatic-cell reprogramming

scientific article

Transcription factor binding dynamics during human ES cell differentiation

scientific article

Transcription factor-mediated epigenetic reprogramming

scientific article

Transcriptional and Chromatin Dynamics of Muscle Regeneration after Severe Trauma

scientific article

Transcriptional and epigenetic dynamics during specification of human embryonic stem cells

scientific article published on 09 May 2013

What can epigenomics do for you?

scientific article published on 23 October 2012

X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs.

scientific article

Zika Virus Alters DNA Methylation of Neural Genes in an Organoid Model of the Developing Human Brain

scientific article published in January 2018

c-Myc is dispensable for direct reprogramming of mouse fibroblasts.

scientific article

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